Incidental neuroendocrine tumor of the appendiceal base less than20 mm in diameter: is appendectomy enough?

The appendixis the second primary site for neuroendocrine tumors. The management of incidentelly discovered neuroendocrine tumor of the appendiceal base less than 20 mm in diameter is still controversal. The aim of this study was to discuss the management of such tumors. Three patients were operated on for acute  appendicitis. Histopathologic examination of surgery specimens revealed neuroendocrine tumors of the appendiceal base less than 20 mm in diameter. Since no one presented with poor prognostic factors, no complementary right hemicolectomy was performed. No recurrence was observed. The existence of  poorprognostic factors at histopathologic examination should indicate complementary right hemicolectomy for incidental neuroendocrine tumor of the appendiceal base less than 20 mm in diameter.Key words: Neuroendocrine tumors, appendix, treatmen

Incidental neuroendocrine tumor of the appendiceal base less than20 mm in diameter: is appendectomy enough? Case series Open Access

Abstract The appendixis the second primary site for neuroendocrine tumors. The management of incidentelly discovered neuroendocrine tumor of the appendiceal base less than 20 mm in diameter is still controversal. The aim of this study was to discuss the management of such tumors. Three patients were operated on for acute appendicitis. Histopathologic examination of surgery specimens revealed neuroendocrine tumors of the appendiceal base less than 20 mm in diameter. Since no one presented with poor prognostic factors, no complementary right hemicolectomy was performed. No recurrence was observed. The existence of poorprognostic factors at histopathologic examination should indicate complementary right hemicolectomy for incidental neuroendocrine tumor of the appendiceal base less than 20 mm in diameter

A multi-scale patch approximation for Poisson problems with a small inhomogeneous inclusion

The paper deals with the multi-scale approximation of the influence of a small inhomogeneity of arbitrary shape in an elastic medium. A new multi-scale patch method is introduced, whose caracteristic is to deal with a large scale problem without inclusion, a small-scale problem on a patch surrounding the inclusion defining a corrector and an iterative procedure between these two problems. Theoretical results of convergence of the iterations, a posteriori error estimate and comparison of the corrector with the asymptotic expansion are provided. The finite element approximation is also addressed together with some numerical tests