26 research outputs found

    Soil suitability index identifies potential areas for groundwater banking on agricultural lands

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    Groundwater pumping chronically exceeds natural recharge in many agricultural regions in California. A common method of recharging groundwater — when surface water is available — is to deliberately flood an open area, allowing water to percolate into an aquifer. However, open land suitable for this type of recharge is scarce. Flooding agricultural land during fallow or dormant periods has the potential to increase groundwater recharge substantially, but this approach has not been well studied. Using data on soils, topography and crop type, we developed a spatially explicit index of the suitability for groundwater recharge of land in all agricultural regions in California. We identified 3.6 million acres of agricultural land statewide as having Excellent or Good potential for groundwater recharge. The index provides preliminary guidance about the locations where groundwater recharge on agricultural land is likely to be feasible. A variety of institutional, infrastructure and other issues must also be addressed before this practice can be implemented widely

    A High Density Consensus Map of Rye (Secale cereale L.) Based on DArT Markers

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    L.) is an economically important crop, exhibiting unique features such as outstanding resistance to biotic and abiotic stresses and high nutrient use efficiency. This species presents a challenge to geneticists and breeders due to its large genome containing a high proportion of repetitive sequences, self incompatibility, severe inbreeding depression and tissue culture recalcitrance. The genomic resources currently available for rye are underdeveloped in comparison with other crops of similar economic importance. The aim of this study was to create a highly saturated, multilocus linkage map of rye via consensus mapping, based on Diversity Arrays Technology (DArT) markers.Recombinant inbred lines (RILs) from 5 populations (564 in total) were genotyped using DArT markers and subjected to linkage analysis using Join Map 4.0 and Multipoint Consensus 2.2 software. A consensus map was constructed using a total of 9703 segregating markers. The average chromosome map length ranged from 199.9 cM (2R) to 251.4 cM (4R) and the average map density was 1.1 cM. The integrated map comprised 4048 loci with the number of markers per chromosome ranging from 454 for 7R to 805 for 4R. In comparison with previously published studies on rye, this represents an eight-fold increase in the number of loci placed on a consensus map and a more than two-fold increase in the number of genetically mapped DArT markers.Through the careful choice of marker type, mapping populations and the use of software packages implementing powerful algorithms for map order optimization, we produced a valuable resource for rye and triticale genomics and breeding, which provides an excellent starting point for more in-depth studies on rye genome organization

    Multifocal Ectopic Purkinje-Related Premature Contractions: A New SCN5A-Related Cardiac Channelopathy.: MEPPC: a new SCN5A-related cardiac channelopathy

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    International audienceOBJECTIVES: The aim of this study was to describe a new familial cardiac phenotype and to elucidate the electrophysiological mechanism responsible for the disease. BACKGROUND: Mutations in several genes encoding ion channels, especially SCN5A, have emerged as the basis for a variety of inherited cardiac arrhythmias. METHODS: Three unrelated families comprising 21 individuals affected by multifocal ectopic Purkinje-related premature contractions (MEPPC) characterized by narrow junctional and rare sinus beats competing with numerous premature ventricular contractions with right and/or left bundle branch block patterns were identified. RESULTS: Dilated cardiomyopathy was identified in 6 patients, atrial arrhythmias were detected in 9 patients, and sudden death was reported in 5 individuals. Invasive electrophysiological studies demonstrated that premature ventricular complexes originated from the Purkinje tissue. Hydroquinidine treatment dramatically decreased the number of premature ventricular complexes. It normalized the contractile function in 2 patients. All the affected subjects carried the c.665G>A transition in the SCN5A gene. Patch-clamp studies of resulting p.Arg222Gln (R222Q) Nav1.5 revealed a net gain of function of the sodium channel, leading, in silico, to incomplete repolarization in Purkinje cells responsible for premature ventricular action potentials. In vitro and in silico studies recapitulated the normalization of the ventricular action potentials in the presence of quinidine. CONCLUSIONS: A new SCN5A-related cardiac syndrome, MEPPC, was identified. The SCN5A mutation leads to a gain of function of the sodium channel responsible for hyperexcitability of the fascicular-Purkinje system. The MEPPC syndrome is responsive to hydroquinidine

    Etude de l'atteinte rénale du syndrome oro-facio-digital de type 1 au sein d'une cohorte de 34 patientes

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    DIJON-BU Médecine Pharmacie (212312103) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

    Soil suitability index identifies potential areas for groundwater banking on agricultural lands

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    Groundwater pumping chronically exceeds natural recharge in many agricultural regions in California. A common method of recharging groundwater — when surface water is available — is to deliberately flood an open area, allowing water to percolate into an aquifer. However, open land suitable for this type of recharge is scarce. Flooding agricultural land during fallow or dormant periods has the potential to increase groundwater recharge substantially, but this approach has not been well studied. Using data on soils, topography and crop type, we developed a spatially explicit index of the suitability for groundwater recharge of land in all agricultural regions in California. We identified 3.6 million acres of agricultural land statewide as having Excellent or Good potential for groundwater recharge. The index provides preliminary guidance about the locations where groundwater recharge on agricultural land is likely to be feasible. A variety of institutional, infrastructure and other issues must also be addressed before this practice can be implemented widely
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