2,564 research outputs found
Projections of the healthcare costs and disease burden due to hepatitis C infection under different treatment policies in Malaysia, 2018-2040
The World Health Organisation (WHO) has set ambitious goals to reduce the global disease burden associated with, and eventually eliminate, viral hepatitis
Chaos in the Gauge/Gravity Correspondence
We study the motion of a string in the background of the Schwarzschild black
hole in AdS_5 by applying the standard arsenal of dynamical systems. Our
description of the phase space includes: the power spectrum, the largest
Lyapunov exponent, Poincare sections and basins of attractions. We find
convincing evidence that the motion is chaotic. We discuss the implications of
some of the quantities associated with chaotic systems for aspects of the
gauge/gravity correspondence. In particular, we suggest some potential
relevance for the information loss paradox.Comment: 29 pages, 11 figure
Sommerfeld Enhancement from Multiple Mediators
We study the Sommerfeld enhancement experienced by a scattering object that
couples to a tower of mediators. This can occur in, e.g., models of secluded
dark matter when the mediator scale is generated naturally by hidden-sector
confinement. Specializing to the case of a confining CFT, we show that
off-resonant values of the enhancement can be increased by ~ 20% for cases of
interest when (i) the (strongly-coupled) CFT admits a weakly-coupled dual
description and (ii) the conformal symmetry holds up to the Planck scale.
Larger enhancements are possible for lower UV scales due to an increase in the
coupling strength of the tower.Comment: 17p, 2 figures; v2 JHEP version (inconsequential typo fixed,
references added
The SKA and "High-Resolution" Science
"High-resolution", or "long-baseline", science with the SKA and its
precursors covers a broad range of topics in astrophysics. In several research
areas, the coupling between improved brightness sensitivity of the SKA and a
sub-arcsecond resolution would uncover truly unique avenues and opportunities
for studying extreme states of matter, vicinity of compact relativistic
objects, and complex processes in astrophysical plasmas. At the same time, long
baselines would secure excellent positional and astrometric measurements with
the SKA and critically enhance SKA image fidelity at all scales. The latter
aspect may also have a substantial impact on the survey speed of the SKA, thus
affecting several key science projects of the instrument.Comment: JENAM-2010: Invited talk at JENAM session S7: The Square Kilometre
Array: Paving the way for the new 21st century radio astronomy paradigm; 9
page
Virtual Sensor Based on a Deep Learning Approach for Estimating Efficiency in Chillers
P. 307-319Intensive use of heating, ventilation and air conditioning
(HVAC) systems in buildings entails an analysis and monitoring of their
e ciency. Cooling systems are key facilities in large buildings, and par-
ticularly critical in hospitals, where chilled water production is needed
as an auxiliary resource for a large number of devices. A chiller plant
is often composed of several HVAC units running at the same time, be-
ing impossible to assess the individual cooling production and e ciency,
since a sensor is seldom installed due to the high cost. We propose a
virtual sensor that provides an estimation of the cooling production,
based on a deep learning architecture that features a 2D CNN (Convolu-
tional Neural Network) to capture relevant features on two-way matrix
arrangements of chiller data involving thermodynamic variables and the
refrigeration circuits of the chiller unit. Our approach has been tested
on an air-cooled chiller in the chiller plant at a hospital, and compared
to other state-of-the-art methods using 10-fold cross-validation. Our re-
sults report the lowest errors among the tested methods and include a
comparison of the true and estimated cooling production and e ciency
for a period of several daysS
Secluded Dark Matter Coupled to a Hidden CFT
Models of secluded dark matter offer a variant on the standard WIMP picture
and can modify our expectations for hidden sector phenomenology and detection.
In this work we extend a minimal model of secluded dark matter, comprised of a
U(1)'-charged dark matter candidate, to include a confining hidden-sector CFT.
This provides a technically natural explanation for the hierarchically small
mediator-scale, with hidden-sector confinement generating m_{gamma'}>0.
Furthermore, the thermal history of the universe can differ markedly from the
WIMP picture due to (i) new annihilation channels, (ii) a (potentially) large
number of hidden-sector degrees of freedom, and (iii) a hidden-sector phase
transition at temperatures T << M_{dm} after freeze out. The mediator allows
both the dark matter and the Standard Model to communicate with the CFT, thus
modifying the low-energy phenomenology and cosmic-ray signals from the secluded
sector.Comment: ~50p, 8 figs; v2 JHEP versio
Neutrino Mass and from a Mini-Seesaw
The recently proposed "mini-seesaw mechanism" combines naturally suppressed
Dirac and Majorana masses to achieve light Standard Model neutrinos via a
low-scale seesaw. A key feature of this approach is the presence of multiple
light (order GeV) sterile-neutrinos that mix with the Standard Model. In this
work we study the bounds on these light sterile-neutrinos from processes like
\mu ---> e + \gamma, invisible Z-decays, and neutrinoless double beta-decay. We
show that viable parameter space exists and that, interestingly, key
observables can lie just below current experimental sensitivities. In
particular, a motivated region of parameter space predicts a value of BR(\mu
---> e + \gamma) within the range to be probed by MEG.Comment: 1+26 pages, 7 figures. v2 JHEP version (typo's fixed, minor change to
presentation, results unchanged
Does the impact of a plant-based diet during pregnancy on birth weight differ by ethnicity? A dietary pattern analysis from a prospective Canadian birth cohort alliance
Objective: Birth weight is an indicator of newborn health and a strong predictor of health outcomes in later life. Signicant variation in diet during pregnancy between ethnic groups in high-income countries provides an ideal opportunity to investigate the influence of maternal diet on birth weight. Setting: Four multiethnic birth cohorts based in Canada (the NutriGen Alliance). Participants: 3997 full-term mother–infant pairs of diverse ethnic groups who had principal component analysis-derived diet pattern scores—plant-based, Western and health-conscious—and birth weight data. Results: No associations were identified between the Western and health-conscious diet patterns and birth weight; however, the plant-based dietary pattern was inversely associated with birth weight (β=−67.6 g per 1-unit increase; P<0.001), and an interaction with non-white ethnicity and birth weight was observed. Ethnically stratified analyses demonstrated that among white Europeans, maternal consumption of a plant-based diet associated with lower birth weight (β=−65.9 g per 1-unit increase; P<0.001), increased risk of small-for-gestational age (SGA; OR=1.46; 95% CI 1.08 to 1.54;P=0.005) and reduced risk of large-for-gestational age (LGA; OR=0.71; 95% CI 0.53 to 0.95;P=0.02). Among South Asians, maternal consumption of a plant-based diet associated with a higher birth weight (β=+40.5 g per 1-unit increase; P=0.01), partially explained by cooked vegetable consumption. Conclusions: Maternal consumption of a plant-based diet during pregnancy is associated with birth weight. Among white Europeans, a plant-based diet is associated with lower birth weight, reduced odds of an infant born LGA and increased odds of SGA, whereas among South Asians living in Canada, a plant-based diet is associated with increased birth weight
Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study.
National Coordinating Centre for Research Methodology; Medical Research Council, UK Department of Health; Chief Scientist OfficeNot peer reviewedPublisher PD
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