Diode laser surgery in the treatment of oral proliferative verrucous leukoplakia associated with HPV-16 infection

Proliferative verrucous leukoplakia (PVL) is an oral potentially malignant disorder, characterized by multifocal expression, progressive clinical evolution, and a high rate of malignant transformation. Evidence-based information regarding optimal PVL management is lacking, due to the paucity of data. The present report describes a case of PVL associated with HPV-16 infection and epithelial dysplasia treated by diode laser surgery, and the outcome of disease clinical remission over a 2-year follow-up period

Nerve Sheath Myxoma of the Tongue

Nerve sheath myxoma (NSM) of the oral mucosa is aslow-growing, benign, often asymptomatic submucosal mass. Wereport on a case of classical NSM of the tongue, with diagnostic andtherapeutic approach to the case.Many NSM arise within the endoneurium of a peripheral nerve. It isa rare condition with no apparent differences between sexes in itsprealence. It can occur at any age..</p

Az égő száj szindrómáról. Diagnózis és etiológia

A dolgozat célja az „égő száj szindrómával” (Burning Mouth Syndrome – BMS) kapcsolatos nemzetközi irodalom legfontosabb megállapításainak összegzése és áttekintése. Az eltelt évtizedek alatt számos kutató gyakorlatban és elméletben is foglalkozott ezzel a különös betegséggel. Ennek ellenére sem világos teljesen a szindróma etiológiája és pathogenezise. A szerzők az etiopathogenezissel kapcsolatos eddigi irodalmi adatokat analizálva nem találtak egyetértést sem a BMS klasszifikációja, sem a diagnózis tekintetében. Ezért egy úgynevezett „Gold Standard” osztályozást tartanak szükségesnek a betegség jobb megértése érdekében, melynek első lépéseit megtették

Anxiety and depression in keratotic oral lichen planus: a multicentric study from the SIPMO

Objectives: Oral lichen planus with exclusive keratotic reticular, papular, and/or plaque-like lesions (K-OLP) is a clinical pattern of OLP that may be associated with a complex symptomatology and psychological alteration. The aim of the study was to evaluate the prevalence of anxiety (A) and depression (D) in patients with K-OLP, analyzing the potential predictors which can affect mental health status. Methods: Three hundred K-OLP patients versus 300 healthy controls (HC) were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), and Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A) were administered. Results: The K-OLP patients showed statistically higher scores in the NRS, T-PRI, HAM-D, and HAM-A compared with the HC (p-value < 0.001**). A and D were found in 158 (52.7%) and 148 (49.3%) K-OLP patients. Strong linear correlations were identified between HAM-A, HAM-D, NRS, T-PRI, and employment status and between HAM-D, HAM-A, NRS, T-PRI, employment status, and female gender. Multivariate logistic regression revealed that HAM-D and HAM-A showed the greatest increase in the R2 value for A and D in the K-OLP patients, respectively (DR2 = 55.5% p-value < 0.001**; DR2 = 56.5% p-value < 0.001**). Conclusions: The prevalence of A and D is higher in the K-OLP patients compared with the HC, also found in K-OLP subjects without pain, suggesting that the processing of pain may be in a certain way independent of the processing of mood. Clinical relevance: Mood disorders and pain assessment should be carefully performed in relation to K-OLP to obtain a complete analysis of the patients

Le basi patogenetiche delle malattie chirurgiche nei piccoli animali. Prima edizione italiana

M.J.BOJRA

Pain Assessment in Oral Medicine through Its Different Dimensions: A Comprehensive Review

Orofacial pain is a complex experience made up of different features and involving various aspects of life. It has demonstrated a connection, especially when chronic, with conditions such as anxiety, depression, and sleep disorders, through paths that still have not been completely clarified. A deep understanding of orofacial pain and its impact on an individual’s life is critical for planning accurate diagnostic and therapeutic approaches. This review seeks to provide a comprehensive overview of the components constituting the pain experience, its implications in an individual’s life, the different tools for multidimensional pain assessment, and the specific applications for each tool. A comprehensive review was performed using the PubMed, Scopus, and Web of Science electronic databases. Ninety-five studies, including observational studies, clinical trials, case–control studies, and case reports, were included and analyzed in this review. Orofacial pain assessment exploits several methods, ranging from clinical evaluation to rating scales, questionnaires, and daily diaries. The choice of the correct instrument requires an evaluation of the type of pain experienced, of the patient’s characteristics and abilities to complete particular tasks, and finally, of the assessment tool features