Microtriatoma trinidadensis (Lent, 1951) (hemiptera, reduviidae, triatominae) : first record in the state of Amazonas, Brazil

Microtriatoma trinidadensis (Lent, 1951), previously known from Venezuela, Colombia, Suriname, Peru, Bolivia, and the Brazilian states of Mato Grosso, Pará, and Tocantins, is reported for the first time in Amazonas state, Brazil. We found in the collection of the Instituto Nacional de Pesquisas da Amazônia an unidentified female specimen of Microtriatoma. The specimen was collected in April 2010, in dried straw and foliage of açai palm, Euterpe precatoria Mart., from Monte Sião, municipality of Codajás, Amazonas state155905909CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESnão temnão te

Bone mineral density, pulmonary function, chronological age, and age at diagnosis in children and adolescents with cystic fibrosis

AbstractObjectiveTo assess bone mineral density in patients with cystic fibrosis (CF), and to correlate it with possible intervening variables.MethodsChildren and adolescents diagnosed with CF, aged 6 to 18 years, followed at the outpatient clinic were included in the study. First, demographic data were collected and, subsequently, patients underwent a spirometric test. All patients answered the Cystic Fibrosis Quality of Life Questionnaire (CFQ) and underwent the six-minute walk test (6MWT) and bone densitometry (DXA).ResultsA total of 25 CF patients were included, of which 56% were males. The mean age was 12.3±3.4 years; mean height was 149.2±14.4 cm; and mean weight was 44.4±13.9 kg. Most results on pulmonary function and bone mineral density (BMD) were within normal limits. The mean forced expiratory volume in one second (FEV) was 92.5±23.6 (% of predicted), mean forced vital capacity (FVC) was 104.4±21.3 (% of predicted), and1 mean BMD z-score was 0.1±1.0. BMD was moderately correlated with FEV (r = 0.43, p = 0.03) and FVC (r = 0.57, p = 0.003). Regarding chronological age and age at diagnosis, a moderate and inverse correlation was also found (r = −0.55, p = 0.004; r = −0.57, p = 0.003, respectively). However, no significant correlations were found with the data from CFQ, 6MWT, and body mass index.ConclusionMost patients had BMD within normal limits and presented a positive correlation with pulmonary function, as well as a negative correlation with chronological age and age at diagnosis

Detecção do vírus da diarréia vírica bovina (BVDV) em touros no Rio Grande do Sul

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Comparisons of Statistical Multifragmentation and Evaporation Models for Heavy Ion Collisions

The results from ten statistical multifragmentation models have been compared with each other using selected experimental observables. Even though details in any single observable may differ, the general trends among models are similar. Thus these models and similar ones are very good in providing important physics insights especially for general properties of the primary fragments and the multifragmentation process. Mean values and ratios of observables are also less sensitive to individual differences in the models. In addition to multifragmentation models, we have compared results from five commonly used evaporation codes. The fluctuations in isotope yield ratios are found to be a good indicator to evaluate the sequential decay implementation in the code. The systems and the observables studied here can be used as benchmarks for the development of statistical multifragmentation models and evaporation codes.Comment: To appear on Euorpean Physics Journal A as part of the Topical Volume "Dynamics and Thermodynamics with Nuclear Degrees of Freedo

Growth inhibitory effects of 3′-nitro-3-phenylamino nor-beta-lapachone against HL-60: A redox-dependent mechanism

AbstractIn this study, the cytotoxicity, genotoxicity and early ROS generation of 2,2-dimethyl-(3H)-3-(N-3′-nitrophenylamino)naphtho[1,2-b]furan-4,5-dione (QPhNO2) were investigated and compared with those of its precursor, nor-beta-lapachone (nor-beta), with the main goal of proposing a mechanism of antitumor action. The results were correlated with those obtained from electrochemical experiments held in protic (acetate buffer pH 4.5) and aprotic (DMF/TBABF4) media in the presence and absence of oxygen and with those from dsDNA biosensors and ssDNA in solution, which provided evidence of a positive interaction with DNA in the case of QPhNO2. QPhNO2 caused DNA fragmentation and mitochondrial depolarization and induced apoptosis/necrosis in HL-60 cells. Pre-treatment with N-acetyl-l-cysteine partially abolished the observed effects related to the QPhNO2 treatment, including those involving apoptosis induction, indicating a partially redox-dependent mechanism. These findings point to the potential use of the combination of pharmacology and electrochemistry in medicinal chemistry

BEC Collapse and Dynamical Squeezing of Vacuum Fluctuations

We analyze the phenomena of Bose Novae, as described by Donley et al [Nature 412, 295 (2001)], by focusing on the behavior of excitations or fluctuations above the condensate, as driven by the dynamics of the condensate (rather than the dynamics of the condensate alone or the kinetics of the atoms). The dynamics of the condensate squeezes and amplifies the quantum excitations, mixing the positive and negative frequency components of their wave functions thereby creating particles which appear as bursts and jets. By analyzing the changing amplitude and particle content of these excitations, our simple physical picture (based on a test field approximation) explains well the overall features of the Bose Novae phenomena and provide excellent quantitative fits with experimental data on several aspects, such as the scaling behavior of the collapse time and the amount of particles in the jet. The predictions of the bursts at this level of approximation is less than satisfactory but may be improved on by including the backreaction of the excitations on the condensate. The mechanism behind the dominant effect -- parametric amplification of vacuum fluctuations and freezing of modes outside of horizon -- is similar to that of cosmological particle creation and structure formation in a rapid quench (which is fundamentally different from Hawking radiation in black holes). This shows that BEC dynamics is a promising venue for doing `laboratory cosmology'.Comment: Latex 36 pages, 6 figure