16,381 research outputs found

    Subtle biological responses to increased CO2 concentrations by Phaeocystis globosa Scherffel, a harmful algal bloom species

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    Recent investigations into the role of carbon dioxide on phytoplankton growth and composition have clearly shown differential effects among species and assemblages, suggesting that increases in oceanic CO2 may play a critical role in structuring lower trophic levels of marine systems in the future. Furthermore, alarming increases in the occurrence of harmful algal blooms (HABs) in coastal waters have been observed, and while not uniform among systems, appear in some manner to be linked to human impacts (eutrophication) on coastal systems. Models of HABs are in their infancy and do not at present include sophisticated biological effects or their environmental controls. Here we show that subtle biological responses occur in the HAB species Phaeocystis globosa Scherffel as a result of CO2 enrichment induced by gentle bubbling. The alga, which has a polymorphic life history involving the formation of both colonies and solitary cells, exhibited altered growth rates of colonial and solitary forms at [CO2] of 750 ppm, as well as increased colony formation. In addition, substantial modifications of elemental and photosynthetic constituents of the cells (C cell(-1), N cell(-1), potential quantum yield, chl a cell(-1)) occurred under elevated CO2 concentrations compared to those found at present CO2 levels. In contrast, other individual and population variables (e. g., colony diameter, total chlorophyll concentration, carbon/nitrogen ratio) were unaffected by increased CO2. Our results suggest that predictions of the future impacts of Phaeocystis blooms on coastal ecosystems and local biogeochemistry need to carefully examine the subtle biological responses of this alga in addition to community and ecosystem effects. Citation: Wang, Y., W. O. Smith Jr., X. Wang, and S. Li (2010), Subtle biological responses to increased CO2 concentrations by Phaeocystis globosa Scherffel, a harmful algal bloom species, Geophys. Res. Lett., 37, L09604, doi: 10.1029/2010GL042666

    Revisiting models of concurrent vowel identification: the critical case of no pitch differences

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    When presented with two vowels simultaneously, humans are often able to identify the constituent vowels. Computational models exist that simulate this ability, however they predict listener confusions poorly, particularly in the case where the two vowels have the same fundamental frequency. Presented here is a model that is uniquely able to predict the combined representation of concurrent vowels. The given model is able to predict listener’s systematic perceptual decisions to a high degree of accuracy

    Three-dimensional flow in Kupffer's Vesicle.

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    Whilst many vertebrates appear externally left-right symmetric, the arrangement of internal organs is asymmetric. In zebrafish, the breaking of left-right symmetry is organised by Kupffer's Vesicle (KV): an approximately spherical, fluid-filled structure that begins to form in the embryo 10 hours post fertilisation. A crucial component of zebrafish symmetry breaking is the establishment of a cilia-driven fluid flow within KV. However, it is still unclear (a) how dorsal, ventral and equatorial cilia contribute to the global vortical flow, and (b) if this flow breaks left-right symmetry through mechanical transduction or morphogen transport. Fully answering these questions requires knowledge of the three-dimensional flow patterns within KV, which have not been quantified in previous work. In this study, we calculate and analyse the three-dimensional flow in KV. We consider flow from both individual and groups of cilia, and (a) find anticlockwise flow can arise purely from excess of cilia on the dorsal roof over the ventral floor, showing how this vortical flow is stabilised by dorsal tilt of equatorial cilia, and (b) show that anterior clustering of dorsal cilia leads to around 40 % faster flow in the anterior over the posterior corner. We argue that these flow features are supportive of symmetry breaking through mechano-sensory cilia, and suggest a novel experiment to test this hypothesis. From our new understanding of the flow, we propose a further experiment to reverse the flow within KV to potentially induce situs inversus.This is the final version of the article. It first appeared from Springer via http://dx.doi.org/10.1007/s00285-016-0967-

    Intravenous immunoglobulin in acute Sydenham's chorea: A systematic review.

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    Abstract Sydenham's chorea (SC) is a major manifestation seen in 25% of patients with acute rheumatic fever. SC is the prototypic autoimmune neurological disorder, which has a less appreciated associated risk of psychiatric morbidity. We undertook a systematic review to examine whether the use of intravenous immunoglobulin affects clinical recovery and morbidity

    Construct, Merge, Solve and Adapt: Application to the repetition-free longest common subsequence problem

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    In this paper we present the application of a recently proposed, general, algorithm for combinatorial optimization to the repetition-free longest common subsequence problem. The applied algorithm, which is labelled Construct, Merge, Solve & Adapt, generates sub-instances based on merging the solution components found in randomly constructed solutions. These sub-instances are subsequently solved by means of an exact solver. Moreover, the considered sub-instances are dynamically changing due to adding new solution components at each iteration, and removing existing solution components on the basis of indicators about their usefulness. The results of applying this algorithm to the repetition-free longest common subsequence problem show that the algorithm generally outperforms competing approaches from the literature. Moreover, they show that the algorithm is competitive with CPLEX for small and medium size problem instances, whereas it outperforms CPLEX for larger problem instances.Peer ReviewedPostprint (author's final draft

    Population genetic diversity in an Iraqi population and gene flow across the Arabian Peninsula

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    Abstract: Y-STRs have emerged as important forensic and population genetic markers for human identification and population differentiation studies. Therefore, population databases for these markers have been developed for almost all major populations around the world. The Iraqi population encompasses several ethnic groups that need to be genetically characterised and evaluated for possible substructures. Previous studies on the Iraqi population based on Y-STR markers were limited by a restricted number of markers. A larger database for Iraqi Arab population needed to be developed to help study and compare the population with other Middle Eastern populations. Twenty-three Y-STR loci included in the PowerPlex Y23 (Promega, Madison, WI, USA) were typed in 254 males from the Iraqi Arab population. Global and regional Y-STR analysis demonstrated regional genetic continuity among the populations of Iraq, the Arabian Peninsula and the Middle East. The Iraqi Arab haplotypes were used to allocate samples to their most likely haplogroups using Athey’s Haplogroup Predictor tool. Prediction indicated predominance (36.6%) of haplogroup J1 in Iraqi Arabs. The migration rate between other populations and the Iraqis was inferred using coalescence theory in the Migrate-n program. Y-STR data were used to test different out-of-Africa migration models as well as more recent migrations within the Arabian Peninsula. The migration models demonstrated that gene flow to Iraq began from East Africa, with the Levantine corridor the most probable passageway out of Africa. The data presented here will enrich our understanding of genetic diversity in the region and introduce a PowerPlex Y23 database to the forensic community

    PHP21 DETERMINANTS OF STATE MEDICAID PER CAPITA PRESCRIPTION DRUG EXPENDITURES:A STRUCTURE EQUATION MODELING APPROACH

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    Simulation of an Optional Strategy in the Prisoner's Dilemma in Spatial and Non-spatial Environments

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    This paper presents research comparing the effects of different environments on the outcome of an extended Prisoner's Dilemma, in which agents have the option to abstain from playing the game. We consider three different pure strategies: cooperation, defection and abstinence. We adopt an evolutionary game theoretic approach and consider two different environments: the first which imposes no spatial constraints and the second in which agents are placed on a lattice grid. We analyse the performance of the three strategies as we vary the loner's payoff in both structured and unstructured environments. Furthermore we also present the results of simulations which identify scenarios in which cooperative clusters of agents emerge and persist in both environments.Comment: 12 pages, 8 figures. International Conference on the Simulation of Adaptive Behavio

    Predicted Causality in Decision Making: The Role of Culture

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    In the wider sense, decision making is embedded in the problem-solving process and its many stages (Davidson and Sternberg, 2003; Güss et al., 2010). In the narrow sense, decision making is understood as the ability to select one of several alternatives and to act accordingly (Güss 2004). Previous research has often focused on decision making in relatively predictable environments with clear goals (e.g., expected utility theory of von Neumann and Morgenstern, 1944). In recent decades the focus has been on decision making heuristics, i.e., strategies or rules of thumb, applied in uncertain situations (e.g., Tversky and Kahneman, 1974; Simon, 1979; Gigerenzer and Gaissmaier, 2011). Causality plays an important role in many cognitive processes – and causal cognition is itself influenced by culture (e.g., Norenzayan and Nisbett, 2000; Medin and Atran, 2004; Beller et al., 2009; Bender and Beller, 2011; for a controversial discussion of causal cognition, see Sperber et al., 1995). Causality is especially important during the decision-making process, because the decision maker has to predict what consequences specific decisions bring about before making a decision
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