950 research outputs found

    Spin polarization evolution in a boost invariant hydrodynamical background

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    Relativistic hydrodynamic equations for particles with spin one-half are used to determine the space-time evolution of the spin polarization in a boost-invariant and transversely homogeneous background. The hydrodynamic approach uses the forms of the energy-momentum and spin tensors based on de Groot, van Leeuwen, and van Weert formalism. Our calculations illustrate how the formalism of hydrodynamics with spin can be used to determine physical observables related to the spin polarization and how the latter can be compared with the experimental data.Comment: 12 pages, 7 figure

    ESTIMATION OF BACOSIDE-A IN BACOPA MONNIERI AERIAL PARTS USING TLC DENSITOMETRY

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    Objective: To estimate bacoside A in Bacopa monnieri aerial parts using a validated TLC densitometric method.Methods: The content of bacoside A was estimated using standardized procedures. A standard curve was prepared by applying different concentrations of the marker. The estimation of bacoside A was achieved on precoated TLC plate using solvent system, i.e., toluene: ethyl acetate: methanol: formic acid (3:3.5:2.5:1) followed by scanning at 225 nm. The developed method was validated for the parameters described in the ICH guidelines.Results: The content of bacoside A was determined to be 1.13±0.019% w/w in B. monnieri aerial parts. The instrumental precision, repeatability, linearity range, correlation coefficient, intra-day precision, inter-day precision, limit of detection (LOD), limit of quantification (LOQ) and accuracy were found to be 0.61% CV, 0.87% CV, 150-900 ng, 0.998, 1.43% CV, 1.79% CV, 32 ng/spot, 92 ng/spot and 97.19±0.39% respectively.Conclusion: The developed method was found to be simple, economic, accurate, precise, and can be utilized for the quantitative as well as qualitative estimation of bacoside A in Bacopa monnieri.Â

    Lectotypification of four species of Indian Trachyspermum (Apiaceae)

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    Four species of Indian Trachyspermum Link are lectotypified here: Trachyspermum falconeri (C.B. Clarke) H. Wolff, T. khasianum (C.B. Clarke) H. Wolff, T. roxburghianum (DC.) H. Wolff and T. villosum (Haines) P.K. Bhattach. & K. Sarkar

    Lectotypification of Indian taxa of Leucas (Lamiaceae)

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    Seventeen species and five varieties of Indian Leucas R. Br. are lectotypified here: Leucas angustissima Sedgw., L. ciliata Benth., L. clarkei Hook.f., L. decemdentata (Willd.) Sm. var. angustifolia (Wall. ex Benth.) V.Singh, L. eriostoma Hook.f. var. lanata Hook.f., L. helicterifolia Haines, L. hyssopifolia Benth., L. lamiifolia Desf., L. lanata Benth., L. lanceaefolia Desf., L. longifolia Benth., L. montana (B. Heyne ex Roth) Spreng., L. prostrata (Hook.f.) Gamble, L. pubescens Benth., L. rosmarinifolia Benth., L. stelligera Wall. ex Benth., L. stricta Benth., L. suffruticosa Benth., L. vestita Benth. var. angustifolia Hook.f., L. vestita Benth. var. oblongifolia Hook.f., L. vestita Benth. var. sericostoma Hook.f. and L. wightiana Wall. ex Benth

    使用済自動車に関わる政策とイノベーションの連動性に関する分析:潜在的な環境への影響と発展途上国への技術移転

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    この博士論文は内容の要約のみの公開(または一部非公開)になっています筑波大学 (University of Tsukuba)201

    ESTIMATION OF BACOSIDE-A IN BACOPA MONNIERI AERIAL PARTS USING TLC DENSITOMETRY

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    Objective: The objective of the present work was to formulate and evaluate a stable, odour free garlic powder loaded floating matrix tablet for the treatment of peptic ulcers. Methods: A gastro-retentive floating matrix tablet (FMT) formulation of garlic powder (GP) was prepared using various concentrations of hydroxypropyl methylcellulose K4M (HPMC K4 M) and effervescent system (sodium bicarbonate and citric acid in 1:1 % w/w) to achieve desirable floating time (FT), floating lag time (FLT) and drug release. Wet granulation method was selected using ethanol as a binder for preparation of tablet. 32 full factorial designs were used for selection of suitable polymer concentration and effervescent system. Nonenteric film coating was applied to mask GP odour. Results: It was observed that FMT with optimum quantities of HPMC K4M and the effervescent system showed 97 % of drug release in 12 h with FT up to 10 h and minimum FLT of 3 min. There was no significant change in FLT, FT and drug content during the stability study of FMT. Conclusion: A stable, sustained release FMT of GP tablets using HPMC K4M and an effervescent system was successfully prepared. This formulation can overcome problems of taste and odour masking, gastric irritation, and loss of active constituents present in garlic

    Design, synthesis and anticonvulsant activity of some new 5,7-dibromoisatin semicarbazone derivatives

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    A series of 5,7-dibromoisatin semicarbazones have been synthesized in good yield, involving aryl urea and aryl semicarbazide formation. The structures of the synthesized compounds were confirmed on the basis of their spectral data. All the compounds were evaluated for anticonvulsant and CNS depressant activities. Anticonvulsant activity was determined after intraperitoneal (i.p.) administration to mice by maximal electroshock (MES) induced seizure method and minimal motor impairment was determined by rotarod test. A computational study was carried out for prediction of pharmacokinetic properties and making them potentially promising agents for the treatment of epilepsy. Compounds (Z)-1-(5,7-dibromo-2-oxoindolin-3-ylidene)-4-(4-chlorophenyl)semicarbazide (DH-05), (Z)-1-(5,7-dibromo-2-oxoindolin-3-ylidene)-4-(3-chloro-4-fluorophenyl)semicarbazide (DH-11) and (Z)-1-(5,7-dibromo-1-methyl-2-oxoindolin-3-ylidene)-4-(3-chloro-4-fluorophenyl)semicarbazide (DH-12) exhibited prominent anticonvulsant effect in the series with little or no neurotoxicity and little CNS depressant effect as compared to standard drug

    Level of cattle rearing practices followed by farmers of Indo-Gangetic plain zone

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    The sample of 90 respondents’ was collected for present study from Shamli district in Indo-Gangetic plain zone. Sugarcane tops were the main fodder crop from October to May months. The sugarcane tops were fed with mix of berseem or mustard cake or others concentrates from January to May. 31.11% respondents used wheat straw mixed with other green fodders followed by jowar, karbi, berseem and lobia as 27.77, 3.33, 2.22 and 2.22%, respectively. It was found that 28.80% animals were milch animal in study area. 38.88% of the respondents provided colostrums within 2 h of birth, 2–4 within hours and the placenta. It was also observed that 43.33% allowed suckling of their calf upto six months. However, 91.11% of the respondents did not dehorn calve. The adoption level regarding feeding practices of cow rearing was providing clean and fresh drinking water which have higher180 score (I rank) of feeding and lowest score was grazing which found only 17score (X ranks), followed 172, 103, 98, 96,102, 97, 69, and 47 score occupied the ranks III, IV, V, VI, VII, VIII and IX, respectively. Out of eight practices included in adoption of calf rearing management practices, Feeding of colostrum to newly born calves within 2 h after the birth was the highest score and occupied (Ist rank). The II and III ranks were occupied by attending newly born calf and proper cleaning of mucous from mouth and nostrils 139 score and trimming of hooves 94 score, respectively. Lighting and disinfection of naval cord, regular deworming of calves, right time method of dehorning and right time castration were VI, V, VI, VII, and VIII ranks, respectively. However, such types of practices are followed for sustainable livestock husbandry in this area since long time

    Study of Antibacterial Activity of Leaf Extracts of Dalbergia Sisso (Roxb.)

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    Antibacterial activity of ethanolic, distilled water and methanol extract of the leaves of Dalbergia Sisso (Roxb.) were studied against Escherichia coli and Bacillus licheniformis by agar well diffusion method. Results obtained showed that the growth of both E.coli and B.licheniformis were inhibited by all the three extracts of dried Leaf Extracts of Dalbergia Sisso (Roxb.). The antibacterial activity of these extracts against selected bacterial stains depends on the type of solvent used for extraction. The present study revealed that Leaf Extracts of Dalbergia Sisso (Roxb.) can be exploited for new potent antibacterial agents
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