Multidimensional Perfectionism in Sport : A Meta-Analytical Review

© 2018 American Psychological Association. The current study provides an updated and meta-analytical review of research examining multidimensional perfectionism in sport. In doing so, studies that report the relationships between perfectionistic strivings, perfectionistic concerns and a range of motivation, emotion/well-being, and performance criterion variables are examined. A literature search yielded 52 studies and 697 effect sizes for 29 criterion variables. Random effects models revealed that perfectionistic strivings displayed small-tomedium relationships with a mix of maladaptive and adaptive motivation and emotion/ well-being, and a small-to-medium relationship with better performance. By contrast, perfectionistic concerns displayed a small-to-medium relationship with maladaptive motivation and emotion/well-being and were unrelated to performance. After controlling for the relationship between the two dimensions of perfectionism, the relationships displayed by residual perfectionistic strivings were indicative of it being less problematic, and the relationships displayed by residual perfectionistic concerns were indicative of it being more problematic than their unresidualized counterparts. There was also some preliminary evidence that some of the relationships were moderated by gender, age, sport type, and instrument. The findings suggest that perfectionistic concerns are clearly maladaptive for athletes, whereas perfectionistic strivings are complex and ambiguous

Severity of Nonalcoholic Fatty Liver Disease is Associated with Development of Metabolic Syndrome: Results of a 5-Year Cohort Study

Aims: Nonalcoholic fatty liver disease (NAFLD) is considered to be a hepatic manifestation of metabolic syndrome (MS). However, a few studies have examined the effect of NAFLD on the development of MS. We evaluated the relationship between the development of MS and clinical severity of NAFLD according to alanine aminotransferase (ALT) levels. Methods: A retrospective cohort study was conducted. Participants who underwent abdominal ultrasonography and blood samplings for health check-ups both in 2005 and 2010 were recruited. NAFLD was diagnosed if a person showed fatty liver on ultrasonography without significant alcohol consumption. Subjects with MS at baseline were excluded. Results: A total of 2,728 subjects met the inclusion criteria. Fatty liver (FL) with normal ALT was found in 369 (13.5%) subjects and FL with elevated ALT in 328 (12.0%). During 5 years of follow up, 582 (21.3%) incident cases of MS developed between 2005 and 2010. The incidence of MS was higher in patients with NAFLD compared to control group (41.2% in FL with elevated ALT, 34.7% in FL with normal ALT and 15.7% in control, p<0.001). Multivariate analysis showed that odds ratio (OR) and 95% confidence interval (CI) for MS increased according to the severity of NAFLD [OR (95% CI), 1.29 (0.97−1.71) in FL with normal ALT and 1.54 (1.18−1.33) in FL with elevated ALT, p=0.01]. Conclusions: We have demonstrated that development of MS is significantly increased according to the clinical severity of NAFLD. These findings have implications in the clinical availability of NAFLD as a predictor of MS

Evaluation of the Beliefs of Parents in Iran about How to Care for Children During Dental Visits

Parents play an important role in their children’s dental care and in their behavior during dental visits. Separating children from their parents during dental visits has been a challenging subject of debate for many years. Therefore, this study aims to evaluate parents’ attitudes about being present during their children’s visits to the dentist. The subjects for this cross-sectional study included 340 Iranian parents of five-10-year-old children who had been referred to dental clinics in Kerman, Iran. For this study, the parents of these children completed self-administered questionnaires. Results showed that 218 parents (64.1%) agreed with leaving the practice room during their child’s treatment, while 122 (35.9%) did not agree. The main reason expressed by 41.3% of the parents for leaving the practicing room was that the dentist would be better able to control the child if they were alone. Another reason, cited by 16.5% of the parents, was not wanting to see their child suffering, and 42.2% said they believed that their child would be better treated if they were not present. Most parents who were in agreement with leaving the practice room while their child was receiving dental care felt this would lead to a better treatment outcome

Systematic mapping shows the need for increased socio-ecological research on oil palm

Abstract In the past century, oil palm has developed from a sustenance crop in West Africa to a major global agricultural commodity, with substantial impacts on biodiversity, the environment, society, and livelihoods. Although the oil palm industry contributes to local and national economies across the tropics, there are significant concerns about the negative effects of oil palm cultivation on biodiversity and ecosystem functioning, as well on local communities and farmers. There is a growing awareness of the need for managing agricultural landscapes more sustainably, and the importance of ecological, social, and also interdisciplinary research to inform this. To understand the current status of research across these areas for oil palm, we carried out a systematic mapping exercise to quantify social, ecological, and interdisciplinary socio-ecological research on oil palm cultivation, assess trends in the research, and to identify priority knowledge gaps in the literature. Literature was searched using adapted preferred reporting items for systematic reviews and meta-analyses and Collaboration for Environmental Evidence protocols. We reviewed 4959 publications on the ecological, social, and socioecological effects of oil palm cultivation. Each publication was classified according to study context (the study site location and type), comparators (the type of comparison the study makes), intervention (the potential action or decision being studied), and outcome (the effects of the intervention on the population). This resulted in 443 classified papers, which we then analyzed in more detail, to identify co-occurrence of different research foci between the disciplines and in socio-ecological research. We found a global increase in oil palm research over the past three decades, with a clear bias to Malaysia and Indonesia, mirroring global production trends. Over 70% of the research was focused on ecological outcomes, 19% on social, and less than 10% interdisciplinary. The majority of studies were conducted within industrial plantations, with comparisons to non-modified habitats, such as forests. Research has focused most on the effects of cultivation on yield, invertebrate biodiversity, and livelihood. To place our findings in context of production of palm oil and sustainability priorities, we used information on regional oil palm production in Tonnes, priorities of sustainable certification bodies, and recognized causes of yield gaps. The most pressing knowledge gaps included a lack of studies on the effects of plantation inputs on pollination and herbivory, the relationship between ecological factors and human health and wellbeing, and comparisons of different management practices within oil palm plantations. We advocate that these gaps become the focus of future research attention, as they lie in identified priority research areas and outcomes are likely to be critical to informing the development of more sustainable palm oil production.Gates Cambridge Trus

Systematic mapping shows the need for increased socio-ecological research on oil palm

Abstract In the past century, oil palm has developed from a sustenance crop in West Africa to a major global agricultural commodity, with substantial impacts on biodiversity, the environment, society, and livelihoods. Although the oil palm industry contributes to local and national economies across the tropics, there are significant concerns about the negative effects of oil palm cultivation on biodiversity and ecosystem functioning, as well on local communities and farmers. There is a growing awareness of the need for managing agricultural landscapes more sustainably, and the importance of ecological, social, and also interdisciplinary research to inform this. To understand the current status of research across these areas for oil palm, we carried out a systematic mapping exercise to quantify social, ecological, and interdisciplinary socio-ecological research on oil palm cultivation, assess trends in the research, and to identify priority knowledge gaps in the literature. Literature was searched using adapted preferred reporting items for systematic reviews and meta-analyses and Collaboration for Environmental Evidence protocols. We reviewed 4959 publications on the ecological, social, and socioecological effects of oil palm cultivation. Each publication was classified according to study context (the study site location and type), comparators (the type of comparison the study makes), intervention (the potential action or decision being studied), and outcome (the effects of the intervention on the population). This resulted in 443 classified papers, which we then analyzed in more detail, to identify co-occurrence of different research foci between the disciplines and in socio-ecological research. We found a global increase in oil palm research over the past three decades, with a clear bias to Malaysia and Indonesia, mirroring global production trends. Over 70% of the research was focused on ecological outcomes, 19% on social, and less than 10% interdisciplinary. The majority of studies were conducted within industrial plantations, with comparisons to non-modified habitats, such as forests. Research has focused most on the effects of cultivation on yield, invertebrate biodiversity, and livelihood. To place our findings in context of production of palm oil and sustainability priorities, we used information on regional oil palm production in Tonnes, priorities of sustainable certification bodies, and recognized causes of yield gaps. The most pressing knowledge gaps included a lack of studies on the effects of plantation inputs on pollination and herbivory, the relationship between ecological factors and human health and wellbeing, and comparisons of different management practices within oil palm plantations. We advocate that these gaps become the focus of future research attention, as they lie in identified priority research areas and outcomes are likely to be critical to informing the development of more sustainable palm oil production.Gates Cambridge Trus

Emerging pharmacotherapy of tinnitus

Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life. Because tinnitus is frequently associated with irritability, agitation, stress, insomnia, anxiety and depression, the social and economic burdens of tinnitus can be enormous. No curative treatments are available. However, tinnitus symptoms can be alleviated to some extent. The most widespread management therapies consist of auditory stimulation and cognitive behavioral treatment, aiming at improving habituation and coping strategies. Available clinical trials vary in methodological rigor and have been performed for a considerable number of different drugs. None of the investigated drugs have demonstrated providing replicable long-term reduction of tinnitus impact in the majority of patients in excess of placebo effects. Accordingly, there are no FDA or European Medicines Agency approved drugs for the treatment of tinnitus. However, in spite of the lack of evidence, a large variety of different compounds are prescribed off-label. Therefore, more effective pharmacotherapies for this huge and still growing market are desperately needed and even a drug that produces only a small but significant effect would have an enormous therapeutic impact. This review describes current and emerging pharmacotherapies with current difficulties and limitations. In addition, it provides an estimate of the tinnitus market. Finally, it describes recent advances in the tinnitus field which may help overcome obstacles faced in the pharmacological treatment of tinnitus. These include incomplete knowledge of tinnitus pathophysiology, lack of well-established animal models, heterogeneity of different forms of tinnitus, difficulties in tinnitus assessment and outcome measurement and variability in clinical trial methodology. © 2009 Informa UK Ltd.Fil: Langguth, Berthold. Universitat Regensburg; AlemaniaFil: Salvi, Richard. State University of New York; Estados UnidosFil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentin

Reliability and Diagnostic Performance of CT Imaging Criteria in the Diagnosis of Tuberculous Meningitis

The original publication is available at http:// www.plosone.orgPublication of this article was funded by the Stellenbosch University Open Access Fund.Introduction: Abnormalities on CT imaging may contribute to the diagnosis of tuberculous meningitis (TBM). Recently, an expert consensus case definition (CCD) and set of imaging criteria for diagnosing basal meningeal enhancement (BME) have been proposed. This study aimed to evaluate the sensitivity, specificity and reliability of these in a prospective cohort of adult meningitis patients. Methods: Initial diagnoses were based on the CCD, classifying patients into: ‘Definite TBM’ (microbiological confirmation), ‘Probable TBM’ (diagnostic score $10), ‘Possible TBM’ (diagnostic score 6–9), ‘Not TBM’ (confirmation of an alternative diagnosis) or ‘Uncertain’ (diagnostic score of ,6). CT images were evaluated independently on two occasions by four experienced reviewers. Intra-rater and inter-rater agreement were calculated using the kappa statistic. Sensitivities and specificities were calculated using both ‘Definite TBM’ and either ‘Definite TBM’ or ‘Probable TBM’ as gold standards. Results: CT scan criteria for BME had good intra-rater agreement (k range 0.35–0.78) and fair to moderate inter-rater agreement (k range 0.20–0.52). Intra- and inter-rater agreement on the CCD components were good to fair (k = ranges 0.47–0.81 and 0.21–0.63). Using ‘Definite TBM’ as a gold standard, the criteria for BME were very specific (61.5%–100%), but insensitive (5.9%–29.4%). Similarly, the imaging components of the CCD were highly specific (69.2–100%) but lacked sensitivity (0–56.7%). Similar values were found when using ‘Definite TBM’ or ‘Probable TBM’ as a gold standard. Discussion: The fair to moderate inter-rater agreement and poor sensitivities of the criteria for BME suggest that little reliance should be placed in these features in isolation. While the presence of the CCD criteria of acute infarction or tuberculoma(s) appears useful as rule-in criteria, their absence is of little help in excluding TBM. The CCD and criteria for BME, as well as any new criteria, need to be standardized and validated in prospective cohort studies.Funding: KB received funding from the Discovery Foundation (Academic Fellowship Award; http://www.discovery.co.za/portal/loggedout-individual/discoverycommunity- about), College of Neurology of South Africa (K.M. Browse Award; http://www.collegemedsa.ac.za/Default.aspx ) and the University of Stellenbosch. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Publisher's versio

Male breast cancer

Male breast cancer (MBC) is a rare disease representing less than 1% of all breast cancers (BC) and less than 1% of cancers in men. Age at presentation is mostly in the late 60s. MBC is recognized as an estrogen-driven disease, specifically related to hyperestrogenism. About 20% of MBC patients have family history for BC. Mutations in BRCA1 and, predominantly, BRCA2, account for approximately 10% of MBC cases. Because of its rarity, MBC is often compared with female BC (FBC). Based on age-frequency distribution, age-specific incidence rate patterns and prognostic factors profiles, MBC is considered similar to late-onset, postmenopausal estrogen/progesterone receptor positive (ER+/PR+) FBC. However, clinical and pathological characteristics of MBC do not exactly overlap FBC. Compared with FBC, MBC has been reported to occur later in life, present at a higher stage, and display lower histologic grade, with a higher proportion of ER+ and PR+ tumors. Although rare, MBC remains a substantial cause for morbidity and mortality in men, probably because of its occurrence in advanced age and delayed diagnosis. Diagnosis and treatment of MBC generally is similar to that of FBC. Men tend to be treated with mastectomy rather than breast-conserving surgery. The backbone of adjuvant therapy or palliative treatment for advanced disease is endocrine, mostly tamoxifen. Use of FBC-based therapy led to the observation that treatment outcomes for MBC are worse and that survival rates for MBC do not improve like FBC. These different outcomes may suggest a non-appropriate utilization of treatments and that different underlying pathogenetic mechanisms may exist between male and female BC