Analisis Pengaruh Kinerja Keuangan Terhadap Harga Saham Perusahaan Manufaktur Yang Terdaftar Di Bursa Efek Indonesia 2012-2014

This study aims to determine the effect of the partial significant between the dividend per share (DPS), Earning Per Share (EPS), Price Earning Ratio (PER), Debt to Equity Ratio (DER), the Current Ratio (CR), Net Profit Margin (NPM ), Return on Assets (ROA) on stock price (Common Price) in Manufacturing Companies Listed on the Stock Exchange and to know significant influence between the dividend per share (DPS), Earning Per Share (EPS), Price Earning Ratio (PER), debt Equity Ratio (DER), the Current Ratio (CR), Net Profit Margin (NPM), Return on Assets (ROA) together on stock price (Common Price) in Manufacturing Companies Listed on the Stock Exchange. The sampling technique used in this research is purposive sampling. The sample used in this study were 71 companies that have positive earnings from 2012 to 2014 year stock in order to obtain 71 x 3 = 213 samples.Based on these results the variable DPS, EPS and ROA have partial significant influence on stock price. Variable PER, DER, NPM and CR does not have a partial significant influence on stock price. F test analysis results showed variable DPS, EPS, PER, DER, CR, NPM and ROA jointly significant effect on stock price. And this shows that the model used is fit. The coefficient of determination with adjusted-R2 of 0.933. This means that 93.3% Stock Price variable variation can be explained by the variable DPS, EPS, PER, DER, CR, NPM and ROA while the remaining 6.7% is explained by other factors outside the model studied

PENGARUH BUDAYA ORGANISASI DAN LINGKUNGAN KERJA TERHADAP KEPUASAN KERJA SERTA DAMPAKNYA PADA PRODUKTIVITAS TENAGA KEPENDIDIKAN DI UNIVERSITAS PASUNDAN BANDUNG

ABSTRAK Pendidikan tinggi di Indonesia dikatakan cukup maju walaupun dalam beberapa konteks masih memiliki problematik yang dihadapi. Selain persoalan yang mengarah pada sistem di Pendidikan tinggi, persoalan lain pendidikan tinggi juga terletak pada output. Peranan manajemen sumber daya manusia terutama tenaga kependidikan dalam lembaga pendidikan sangat berkontribusi dalam membantu meningkatkan mutu pendidikan, Berdasarkan fenomena yang terjadi maka diangkatlah judul penelitian ini yaitu “Pengaruh budaya organisasi dan lingkungan kerja terhadap kepuasan kerja yang berdampak pada produktivitas tenaga kependidikan Universitas Pasundan Bandung.Penelitian in bertujuan untuk mengetahui pengaruh budaya organisasi dan lingkungan kerja terhadap kepuasan kerja yang berdampak pada produktivitas tenaga kependidikan di Universitas Pasundan Bandung. Metode yang digunakan adalah metode desktriptif dan verifikatif, teknik sampling yang digunakan adalah probably sampling dengan jumlah sampel sebanyak 80 responden, teknik pengumpulan data yang digunakan penelitian lapangan dan penelitian kepustakaan. Pengujian instrumen penelitian menggunakan uji validitas, uji reliabilitas, uji normalitas. Metode analisis data yang digunakan path analysis, metodh of successive interval (MSI), korelasi berganda dan koefisien determinasi dengan bantuan software SPSS 26. Pengujian hipotesis dilakukan baik secara parsial dengan (Uji T) maupun secara simultan melalui (Uji F). Hasil penelitian ini menunjukan budaya organisasi, lingkungan kerja dan kepuasan kerja berada pada kategori kurang baik serta terdapat pengaruh dan signifikan baik secara parsial maupun simultan. Hasil analisis data menunjukan besarnya pengaruh budaya organisasi dan lingkungan kerja terhadap kepuasan kerja sebesar 83,3%, dan budaya oranisasi berpengaruh lebih besar dari lingkungan kerja. Secara parsial kepuasan kerja berpengaruh positif dan signifikan sebesar 66,3% terhadap produktivitas tenaga kependidikan di Universitas Pasundan Bandung. Kata kunci : Budaya Organisasi, Lingkungan Kerja, Kepuasan Kerja dan Produktivita

Pengaruh Kepuasan Kerja dan Komitmen Organisasional Terhadap Kualitas Layanan Di PT. Asuransi Jasindo (Persero) Kantor Cabang Korporasi Dan Ritel Bandung.

This study aims to determine job satisfaction, organizational commitment and service quality as well as to analyze the influence of job satisfaction and organizational commitment to the service quality. The object of this research is PT. Asuransi Jasindo (Persero) Corporate and Retail Branch Office Bandung. Descriptive method is used with quantitative approach. Data collection techniques used were observation, interviews and questionnaires with a sample of 70 people. The hypothesis tested by using path analysis. The results showed that job satisfaction, organizational commitment, and quality of service are in the quite well category. Job satisfaction has reached 18.93% influence on service quality, organizational commitment has the effect of 29.79% of job satisfaction. Overall influence of service quality and organizational commitment on service quality is 48.72%

Immune function in female B6C3F1 mice is modulated by DE-71, a commercial polybrominated diphenyl ether mixture

Polybrominated diphenyl ethers (PBDEs) are an important class of flame-retardants that are environmentally persistent and bioaccumulative. Toxicity of these compounds has become a concern because detectable levels of PBDEs are present in humans and wildlife and they are structurally similar to polychlorinated biphenyls (PCBs). This study examined the effects of the commercial penta-BDE mixture, DE-71, in adult female B6C3F1 mice on hematology, serum clinical chemistry, thyroid hormones, tissue histology, and several immunotoxicity end-points (lymphocyte proliferation, NK cell activity, splenic immunophenotypes, and SRBC-specific-IgM production). Mice were exposed via oral gavage for 28 days to achieve total administered doses (TAD) of 0, 0.5, 5, 50, or 100 mg/kg. No changes in histology, clinical chemistry, body or organ weights were observed. Serum total T3 and T4 levels were not altered by any of the DE-71 treatments. Peripheral blood monocyte numbers were decreased by the 0.5, 5, and 50 mg/kg treatments, but not by the 100 mg/kg TAD concentration. Compared to controls, mitogen-stimulated T- and B-cell proliferation was increased by the 100 mg/kg TAD concentration (ED50 = 60 mg/kg TAD [2.14 mg/kg/day] and 58 mg/kg TAD [2.57 mg/kg/day], respectively). NK cell activity was decreased compared to controls by the 100 mg/kg TAD concentration (ED50 = 20 mg/kg TAD [0.7 mg/kg/day]). No alterations were noted in thymic T-cell populations or in SRBC-specific-IgM production. Numbers of CD19+CD21−, CD19+CD21+, CD4+CD8−, CD4−CD8+, CD4−CD8−, and MHC-II+ cells in the spleen were not affected. However, the numbers of splenic CD4+CD8+ cells were decreased compared to the controls by 0.5, 5, and 100 mg/kg TAD. This study provides an assessment of the systemic toxicity and immunotoxicity of DE-71, and indicates that immune parameters are modulated at exposure concentrations lower than previously reported

Massive stars as thermonuclear reactors and their explosions following core collapse

Nuclear reactions transform atomic nuclei inside stars. This is the process of stellar nucleosynthesis. The basic concepts of determining nuclear reaction rates inside stars are reviewed. How stars manage to burn their fuel so slowly most of the time are also considered. Stellar thermonuclear reactions involving protons in hydrostatic burning are discussed first. Then I discuss triple alpha reactions in the helium burning stage. Carbon and oxygen survive in red giant stars because of the nuclear structure of oxygen and neon. Further nuclear burning of carbon, neon, oxygen and silicon in quiescent conditions are discussed next. In the subsequent core-collapse phase, neutronization due to electron capture from the top of the Fermi sea in a degenerate core takes place. The expected signal of neutrinos from a nearby supernova is calculated. The supernova often explodes inside a dense circumstellar medium, which is established due to the progenitor star losing its outermost envelope in a stellar wind or mass transfer in a binary system. The nature of the circumstellar medium and the ejecta of the supernova and their dynamics are revealed by observations in the optical, IR, radio, and X-ray bands, and I discuss some of these observations and their interpretations.Comment: To be published in " Principles and Perspectives in Cosmochemistry" Lecture Notes on Kodai School on Synthesis of Elements in Stars; ed. by Aruna Goswami & Eswar Reddy, Springer Verlag, 2009. Contains 21 figure

Electroless plating as surface finishing in electronic packaging

Electroless plating is one type of surface finish deposition method in electronic packaging. With advancements in electronic products, the industry is shifting toward this process based on its advantages. However, the electroless plating process itself is unstable. Its stability fully depends on the substrate material, the pretreatment process, the type of solution used, and the pH and temperature during plating. In this article, focus is given to the three different types of electroless plating formulations used in electronic packaging that have been studied by previous researchers: electroless nickel, electroless palladium, and electroless gold

Using citizen science to understand floating plastic debris distribution and abundance: A case study from the North Cornish coast (United Kingdom)

This is the final version. Available on open access from Elsevier via the DOI in this recordData availability: Data will be made available on request.Citizen science is now commonly employed to collect data on plastic pollution and is recognised as a valuable tool for furthering our understanding of the issue. Few studies, however, use citizen science to gather information on water-borne plastic debris. Here, citizen scientists adopted a globally standardised methodology to sample the sea-surface for small (1-5 mm) floating plastic debris off the Cornish coast (UK). Twenty-eight trawls were conducted along five routes, intersecting two Marine Protected Areas. Of the 509 putative plastic items, fragments were most common (64%), then line (19%), foam (7%), film (6%), and pellets (4%). Fourier-transform infrared spectroscopy identified the most common polymer type as polyethylene (31%), then nylon (12%), polypropylene (8 %), polyamide (5%) and polystyrene (3%). This study provides the first globally comparative baseline of floating plastic debris for the region (mean: 8512 items km−2), whilst contributing to an international dataset aimed at understanding plastic abundance and distribution worldwide.Polzeath Marine Conservation GroupSt Agnes Marine Conservation GroupNewquay Sea Safaris and FishingEngineering and Physical Sciences Research Council (EPSRC)Natural Environment Research Council (NERC

Control Growth Factor Release Using a Self-Assembled [polycation∶heparin] Complex

The importance of growth factors has been recognized for over five decades; however their utilization in medicine has yet to be fully realized. This is because free growth factors have short half-lives in plasma, making direct injection inefficient. Many growth factors are anchored and protected by sulfated glycosaminoglycans in the body. We set out to explore the use of heparin, a well-characterized sulfated glycosaminoglycan, for the controlled release of fibroblast growth factor-2 (FGF-2). Heparin binds a multitude of growth factors and maintains their bioactivity for an extended period of time. We used a biocompatible polycation to precipitate out the [heparin∶FGF-2] complex from neutral buffer to form a release matrix. We can control the release rate of FGF-2 from the resultant matrix by altering the molecular weight of the polycation. The FGF-2 released from the delivery complex maintained its bioactivity and initiated cellular responses that were at least as potent as fresh bolus FGF-2 and fresh heparin stabilized FGF-2. This new delivery platform is not limited to FGF-2 but applicable to the large family of heparin-binding growth factors

Mapping gene associations in human mitochondria using clinical disease phenotypes

Nuclear genes encode most mitochondrial proteins, and their mutations cause diverse and debilitating clinical disorders. To date, 1,200 of these mitochondrial genes have been recorded, while no standardized catalog exists of the associated clinical phenotypes. Such a catalog would be useful to develop methods to analyze human phenotypic data, to determine genotype-phenotype relations among many genes and diseases, and to support the clinical diagnosis of mitochondrial disorders. Here we establish a clinical phenotype catalog of 174 mitochondrial disease genes and study associations of diseases and genes. Phenotypic features such as clinical signs and symptoms were manually annotated from full-text medical articles and classified based on the hierarchical MeSH ontology. This classification of phenotypic features of each gene allowed for the comparison of diseases between different genes. In turn, we were then able to measure the phenotypic associations of disease genes for which we calculated a quantitative value that is based on their shared phenotypic features. The results showed that genes sharing more similar phenotypes have a stronger tendency for functional interactions, proving the usefulness of phenotype similarity values in disease gene network analysis. We then constructed a functional network of mitochondrial genes and discovered a higher connectivity for non-disease than for disease genes, and a tendency of disease genes to interact with each other. Utilizing these differences, we propose 168 candidate genes that resemble the characteristic interaction patterns of mitochondrial disease genes. Through their network associations, the candidates are further prioritized for the study of specific disorders such as optic neuropathies and Parkinson disease. Most mitochondrial disease phenotypes involve several clinical categories including neurologic, metabolic, and gastrointestinal disorders, which might indicate the effects of gene defects within the mitochondrial system. The accompanying knowledgebase (http://www.mitophenome.org/) supports the study of clinical diseases and associated genes

Bladder metastases of appendiceal mucinous adenocarcinoma: a case presentation

<p>Abstract</p> <p>Background</p> <p>Appendiceal adenocarcinoma is rare with a frequency of 0.08% of all surgically removed appendices. Few cases of appendiceal carcinoma infiltrating the bladder wall for spatial contiguity have been documented.</p> <p>Case Presentation</p> <p>A case is reported of a 45-years old woman with mucinous cystadenocarcinoma of the appendix with bladder metastasis. Although ultrasonography and voided urinary cytology were negative, abdomen computed tomography (CT) scan and cystoscopy and subsequent pathological examination revealed a mass exclusively located in the anterior wall of the bladder. Histopathology of the transurethral bladder resection revealed a bladder adenocarcinoma [6 cm (at the maximum diameter) × 2,5 cm; approximate weight: 10 gr] with focal mucinous aspects penetrating the muscle and perivisceral fat. Laparotomy evidenced the presence of a solid mass of the appendix (2,5 cm × 3 cm × 2 cm) extending to the loco-regional lymph nodes. Appendectomy and right hemicolectomy, linfoadenectomy and partial cystectomy were performed. The subsequent pathological examination revealed a mucinous cystadenocarcinoma of the appendix with metastatic cells colonising the anterior bladder wall and several colic lymph nodes.</p> <p>Conclusions</p> <p>The rarity of the appendiceal carcinoma invading the urinary bladder and its usual involvement of nearest organs and the posterior bladder wall, led us to describe this case which demonstrates the ability of the appendiceal cancer to metastasize different regions of urinary bladder.</p