17 research outputs found
The effective bandwidth problem revisited
The paper studies a single-server queueing system with autonomous service and
priority classes. Arrival and departure processes are governed by marked
point processes. There are buffers corresponding to priority classes,
and upon arrival a unit of the th priority class occupies a place in the
th buffer. Let , denote the quota for the total
th buffer content. The values are assumed to be large, and
queueing systems both with finite and infinite buffers are studied. In the case
of a system with finite buffers, the values characterize buffer
capacities.
The paper discusses a circle of problems related to optimization of
performance measures associated with overflowing the quota of buffer contents
in particular buffers models. Our approach to this problem is new, and the
presentation of our results is simple and clear for real applications.Comment: 29 pages, 11pt, Final version, that will be published as is in
Stochastic Model
A new discrete velocity method for Navier-Stokes equations
The relation between Latttice Boltzmann Method, which has recently become
popular, and the Kinetic Schemes, which are routinely used in Computational
Fluid Dynamics, is explored. A new discrete velocity model for the numerical
solution of the Navier-Stokes equations for incompressible fluid flow is
presented by combining both the approaches. The new scheme can be interpreted
as a pseudo-compressibility method and, for a particular choice of parameters,
this interpretation carries over to the Lattice Boltzmann Method.Comment: 28 pages, 8 figure
Moduli of Abelian varieties, Vinberg theta-groups, and free resolutions
We present a systematic approach to studying the geometric aspects of Vinberg
theta-representations. The main idea is to use the Borel-Weil construction for
representations of reductive groups as sections of homogeneous bundles on
homogeneous spaces, and then to study degeneracy loci of these vector bundles.
Our main technical tool is to use free resolutions as an "enhanced" version of
degeneracy loci formulas. We illustrate our approach on several examples and
show how they are connected to moduli spaces of Abelian varieties. To make the
article accessible to both algebraists and geometers, we also include
background material on free resolutions and representation theory.Comment: 41 pages, uses tabmac.sty, Dedicated to David Eisenbud on the
occasion of his 65th birthday; v2: fixed some typos and added reference
Large closed queueing networks in semi-Markov environment and its application
The paper studies closed queueing networks containing a server station and
client stations. The server station is an infinite server queueing system,
and client stations are single-server queueing systems with autonomous service,
i.e. every client station serves customers (units) only at random instants
generated by a strictly stationary and ergodic sequence of random variables.
The total number of units in the network is . The expected times between
departures in client stations are . After a service completion
in the server station, a unit is transmitted to the th client station with
probability , and being processed in the th client
station, the unit returns to the server station. The network is assumed to be
in a semi-Markov environment. A semi-Markov environment is defined by a finite
or countable infinite Markov chain and by sequences of independent and
identically distributed random variables. Then the routing probabilities
and transmission rates (which are expressed via
parameters of the network) depend on a Markov state of the environment. The
paper studies the queue-length processes in client stations of this network and
is aimed to the analysis of performance measures associated with this network.
The questions risen in this paper have immediate relation to quality control of
complex telecommunication networks, and the obtained results are expected to
lead to the solutions to many practical problems of this area of research.Comment: 35 pages, 1 figure, 12pt, accepted: Acta Appl. Mat
Role of the factor VIII-binding capacity of endogenous von Willebrand factor on the development of factor VIII inhibitors in patients with severe hemophilia A
International audienc
The CHEMDNER corpus of chemicals and drugs and its annotation principles
The automatic extraction of chemical information from text requires the recognition of chemical entity mentions as one
of its key steps. When developing supervised named entity recognition (NER) systems, the availability of a large,
manually annotated text corpus is desirable. Furthermore, large corpora permit the robust evaluation and comparison
of different approaches that detect chemicals in documents. We present the CHEMDNER corpus, a collection of 10,000
PubMed abstracts that contain a total of 84,355 chemical entity mentions labeled manually by expert chemistry
literature curators, following annotation guidelines specifically defined for this task. The abstracts of the CHEMDNER
corpus were selected to be representative for all major chemical disciplines. Each of the chemical entity mentions was
manually labeled according to its structure-associated chemical entity mention (SACEM) class: abbreviation, family,
formula, identifier, multiple, systematic and trivial. The difficulty and consistency of tagging chemicals in text was
measured using an agreement study between annotators, obtaining a percentage agreement of 91. For a subset of the
CHEMDNER corpus (the test set of 3,000 abstracts) we provide not only the Gold Standard manual annotations, but also
mentions automatically detected by the 26 teams that participated in the BioCreative IV CHEMDNER chemical mention
recognition task. In addition, we release the CHEMDNER silver standard corpus of automatically extracted mentions
from 17,000 randomly selected PubMed abstracts. A version of the CHEMDNER corpus in the BioC format has been
generated as well. We propose a standard for required minimum information about entity annotations for the
construction of domain specific corpora on chemical and drug entities. The CHEMDNER corpus and annotation
guidelines are available at: http://www.biocreative.org/resources/biocreative-iv/chemdner-corpus