Using Semantic Technologies in Digital Libraries- A Roadmap to Quality Evaluation

Abstract. In digital libraries semantic techniques are often deployed to reduce the expensive manual overhead for indexing documents, maintaining metadata, or caching for future search. However, using such techniques may cause a decrease in a collection’s quality due to their statistical nature. Since data quality is a major concern in digital libraries, it is important to be able to measure the (loss of) quality of metadata automatically generated by semantic techniques. In this paper we present a user study based on a typical semantic technique use

Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci.

Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, but the nature of the suggestive comorbidity is still unknown. We used a novel genetic pleiotropy-informed conditional False Discovery Rate (FDR) method to identify single nucleotide polymorphisms (SNPs) associated with BMD by leveraging cardiovascular disease (CVD) associated disorders and metabolic traits. By conditioning on SNPs associated with the CVD-related phenotypes, type 1 diabetes, type 2 diabetes, systolic blood pressure, diastolic blood pressure, high density lipoprotein, low density lipoprotein, triglycerides and waist hip ratio, we identified 65 novel independent BMD loci (26 with femoral neck BMD and 47 with lumbar spine BMD) at conditional FDR < 0.01. Many of the loci were confirmed in genetic expression studies. Genes validated at the mRNA levels were characteristic for the osteoblast/osteocyte lineage, Wnt signaling pathway and bone metabolism. The results provide new insight into genetic mechanisms of variability in BMD, and a better understanding of the genetic underpinnings of clinical comorbidity

MultiBeeBrowse - Accessible Browsing on Unstructured Metadata

Abstract. Growing abundance of information on the Internet, especially the Next Generation Internet, poses even more challenges on more efficient information management; hence it has brought attention of the researchers to the faceted navigation. Existing solutions, however, do not address the majority of users, who are still inexperienced in using the faceted navigation solutions or who do not understand underlying concepts of the Semantic Web technologies, or both. The query refinement process, while using the faceted navigation interface, is more complex than, e.g., refining a simple keyword-based query. In this article we present MultiBeeBrowse (MBB), an accessible faceted navigation solution that solves aforementioned problems in the browsing environment. We present how to improve users ’ access to their history of refinements; we discuss how users can share their browsing experience. And last bust not least, we present an adaptable user interface, which aims to decrease information overload.

D-FOAF: Distributed Identity Management with Access Rights Delegation

WWW provides a large number of services, which often require identification of it¿s users. This has lead to the fact that today users have to maintain a large number of different credentials for different websites - distributed or shared identification system are not widely deployed. Furthermore current authorisation systems requires strict centralisation of the authorisation procedure - users themselves are usually not enabled to authorise their trusted friends to access services, although often this would be beneficial for services and businesses on the Web. In this article we present D-FOAF, a distributed identity management system which deploys social networks. We show how information inherent in social networks can be utilised to provide community driven access rights delegation and we analyse algorithms for managing distributed identity, authorisation and access rights checking. Finally we show how the social networking information can be protected in a distributed environment.peer-reviewe

JeromeDL - Adding Semantic Web Technologies to Digital Libraries

Abstract. In recent years more and more information has been made available on the Web. High quality information is often stored in dedicated databases of digital libraries, which are on their way to become expanding islands of well organized information. However, managing this information still poses challenges. The Semantic Web provides technologies that are about help to meet these challenges. In this article we present JeromeDL, a full fledged open-source digital library system. We exemplify how digital library content management can benefit from the Semantic Web. We define and evaluate browsing and searching features. We describe how the semantic descriptions of resources and users profiles improve the usability of a digital library. We present how digital libraries can be interconnected into one heterogeneous database with use of semantic technologies.

Associations between baseline demographic, clinical and lifestyle factors, and changes in fatigue, depression, and health-related quality of life in long-term cancer survivors: a cohort study

Purpose To investigate the longitudinal associations between demographic, clinical and lifestyle factors, and changes in patient-reported outcomes (PROs) in cancer survivors 6-9 years post-diagnosis in Western Australia. Methods A total of 290 individuals participated in this study. Three-quarters of participants were female, and 55%, 31%, and 14% were survivors of breast cancer, colon cancer, and non-Hodgkin lymphoma (NHL), respectively. PROs (fatigue, depression, and health-related quality of life (HRQOL)) were reported at two time points (2012-13 and 2017). Descriptive statistics were used to assess the overall changes over time and linear mixed models were used to identify factors associated with changes over time, after adjusting for confounders. Results No significant changes were observed in PROs between time point 1 and follow-up at the population level, yet a notable proportion of participants (23% for fatigue, 10% for depression, and 39% for HRQOL) reported a negative minimal clinically important difference (MCID). Being non-Caucasian and having had NHL were associated with negative changes over time. Being obese and having had radiotherapy were related to improved outcomes. Conclusion Cancer survivors whose levels of fatigue, depression, and quality of life are compromised during cancer treatment may require intervention even 6-9 years post-treatment. Our results suggest particular attention should be paid to those who are non-Caucasian and who have had NHL. This is crucial for providing appropriate care and to support those who are at increased risk of deteriorating naturally over time

The late Quaternary sedimentary record of Reykjanes Ridge, North Atlantic

From the 17th International Radiocarbon Conference held in Jerusalem, Israel, June 18-23, 2000.Variability in surface and deep ocean circulation in the North Atlantic is inferred from grain-size characteristics and the composition of terrigenous sediments from a deep-sea core taken on Reykjanes Ridge, south of Iceland. End-member modeling of grain size data shows that deep-ocean circulation in this area decreased significantly during periods of maximum iceberg discharge. The episodes of reduced circulation correlate with the cold and abrupt warming phases of the Dansgaard-Oeschger cycles as recognized in the Greenland ice cores.The Radiocarbon archives are made available by Radiocarbon and the University of Arizona Libraries. Contact [email protected] for further information.Migrated from OJS platform February 202