Identification of most relevant variables and processes to assess the environmental impacts of remediation technologies along their life cycles: Focus on the waste management scenarios

The application of Life Cycle Assessment (LCA) to remediation technologies is still not a consolidated practice and it is especially lacking in the assessment of the environmental impacts associated to the management of the waste produced during remediation. This study aims at addressing these methodological gaps by identifying the typologies of waste typically generated during the remediation of a contaminated site and classifying them according to the European Waste Catalogue (EWC) codes. Thereafter, the following steps are: (i) the identification of the waste management scenarios (WMSs) applicable to the identified waste typologies, (ii) the selection of Life Cycle Assessment processes that can be used to assess the impacts of the different WMSs and (iii) the quantification and comparison of the environmental impacts caused by the different WMSs applied considering hazardousness levels to which the same waste may belong in relation to its contamination levels and characteristics: inert, non-hazardous and hazardous waste (Waste Framework Directive 2008/98/EC). As results, a matrix reporting the classes and typologies of waste, their EWC codes, their different WMSs and the suitable LCA processes from the Ecoinvent database that can be applied to each EWC within a specific WMS, has been developed. Additionally, the comparative assessment of the impacts caused by the Ecoinvent processes applicable to the same waste typology within the same WMS has been performed to support the selection of the most appropriate WMS case by case

The Relationship between Life Course Socioeconomic Conditions and Objective and Subjective Memory in Older Age.

While objective memory performance in older adults was primarily shown to be affected by education as indicator of life course socioeconomic conditions, other life course socioeconomic conditions seem to relate to subjective memory complaints. However, studies differ in which life course stages were investigated. Moreover, studies have explored these effects in an isolated way, but have not yet investigated their unique effect when considering several stages of the life course simultaneously. This study, therefore, examined the respective influence of socioeconomic conditions from childhood up to late-life on prospective memory (PM) performance as an objective indicator of everyday memory as well as on subjective memory complaints (SMC) in older age using structural equation modeling. Data came from two waves of the Vivre-Leben-Vivere aging study (n=993, Mage=80.56). The results indicate that only socioeconomic conditions in adulthood significantly predicted late-life PM performance. PM performance was also predicted by age and self-rated health. In contrast, SMC in older age were not predicted by socioeconomic conditions at any stage of the life course but were predicted by level of depression. In line with the cognitive reserve hypothesis, present results highlight the significance of education and occupation (adulthood socioeconomic conditions) for cognitive functioning in later life

Enhancing Inhibitory Control in Older Adults: A Biofeedback Study.

Multidomain interventions based on bio-/neurofeedback have proven useful in improving executive functions. The present study aimed to explore the potential efficacy and feasibility of an intervention that combined Heart Rate Variability Biofeedback (HRV-BF) and Near Infrared Hemoencephalography Neurofeedback (nirHEG-NF) on inhibitory control (IC) of healthy older adults. Thirty-four participants were randomly assigned to two groups: the biofeedback group (received a 10-week combined intervention of HRV-BF and nirHEG-NF) and the active control group (received a similar protocol without real-time biofeedback). Besides cognitive outcomes, the study examined pre- and post-changes in autonomic regulation and prefrontal blood oxygenation at rest and during training. Results revealed training-induced inhibitory control gains in one of the two interference tasks, whereas no effect was found on response inhibition. After the intervention, HRV increased in participants with the lowest levels of HRV at baseline. Although older adults increased blood oxygenation during training, no significant pre- and post-changes were found in blood flow oxygenation. These findings not only suggest that HRV-BF and nirHEG-NF potentially improve performance in certain subcomponents of inhibition (i.e., interference vs. response inhibition), but it may also be beneficial for parasympathetic activity in participants with low HRV and for increasing blood flow oxygenation on prefrontal areas during training

Analysis of multichannel EEG synchronization before and during generalized epileptic seizures

The genesis of seizures in idiopatic generalized epilepsy (IGE) is investigated in a population of 10 patients (5 affected by Juvenile Absence Epilepsy, or JAE, and 5 affected by Juvenile Myoclonic Epilepsy, or JME). Aim of the study is the identification of a talamic or cortical origin of the paroxistic activity. The mutual synchronization among EEG channels was evaluated trough the cross conditional corrected entropy (CCCE) calculated on the row signals and after the application of the Laplacian operator. In JAE patients a leading role of the left frontal lobe was put into evidence in correspondence of the seizure, while in JME patients a leading electrode was not identified, suggesting a possible talamic origin of the seizure

Sustainability assessment of two digestate treatments: A comparative life cycle assessment

Digestate derived from the anaerobic digestion of biowaste is a nutrient-rich substance whose direct use on land is not permitted by the Italian Legislation. The possibility of recovering its nutrients can be given by the processes of stabilisation and sanitation required by the Italian Legislation. Among these processes, composting and calcium hydrolysis with neutralization (CHN) permit to obtain useful soil improvers like compost and defecation gypsum (DG). In this paper a gate-to-gate Life Cycle Assessment (LCA) of these two processes is performed to evaluate their relative environmental sustainability, by using the ReCiPe H midpoint and endpoint impact assessment methods. The functional units (FUs) used in this analysis are one tonne of digestate treated by each process, and the amount of compost and DG necessary to amend one hectare of maize cultivation. Data used in the assessment were collected from plants located in Northern Italy and were referred to one year of operation. The processes of transport and spreading on land of the final products were not considered. The results of both the analyses show that CHN is the process with the largest environmental impacts, mainly due to the use of chemicals (i.e., sulfuric acid and calcium oxide). For both processes and FUs, the most impacted midpoint categories are Natural land transformation, Marine ecotoxicity and Freshwater ecotoxicity. Among the endpoint categories Resources is the most impacted one (followed by Human Health and Ecosystems), for both FUs, although showing larger differences for the agronomic use

Flavonoid Oligoglycosides from Ophioglossum vulgatum L. Having Wound Healing Properties

Two new glycosylated and acylated flavonols, viz. quercetin-3-O-[(6-caffeoyl)-\u3b2-glucopyranosyl (1\u21923)\u3b1-rhamnopyranoside]-7-O-\u3b1-rhamnopyranoside (2), and kaempferol-3-O-[(6-caffeoyl)-\u3b2-glucopyranosyl (1\u21923)\u3b1-rhamnopyranoside]-7-O-\u3b1-rhamnopyranoside (3), together with the known quercetin-3-O-methyl ether (1), were isolated from the aerial parts of the fern Ophioglossum vulgatum L. Their structures were established by means of 1D and 2D NMR spectra, as well as ESI\u2011MS and ESI-HRMS spectra. Compounds 1\u20133 were all found to be active in scratch-wound healing assays on keratinocytes, with 3 being the most active one and showing maximum activity at 20 \u3bcM

Laboratory diagnosis of renal failure: urine conductivity and tubular function.

AIM: Conductivity is a measure of a material's ability to conduct an electric current and it works thanks to movable charges. Conductivity in urine is directly proportional to ionic contents. The aim of this study was to evaluate the significance of urine conductivity by using the Sismex UF-100 analyser in correlations with other surrogate parameters of osmolality and renal diuresis, relative density, electrolytes and creatinine concentration. METHODS: For this study 140 urine samples were submitted for diagnostic urinalysis to the Clinical Pathology laboratory. Samples were collected from 70 healthy subjects, 42 diabetics with poor metabolic control and significant glicosuria, 28 patients with monoclonal gammopathy of uncertain significance, with significant proteinuria. All the samples were assessed for conductivity (UF-100 Sysmex), relative density (refract meter Zeiss), sodium, potassium, chlorine, creatinine, urea, glucose, protein (Olympus AU-2700). RESULTS: Urine conductivity appears to be related to ionic concentration but not to glucose and/or protein presence. CONCLUSIONS: This study results suggest that conductivity determination should be useful in diabetic patients to study the tubular function minimising interferences due to osmotic action of glucose