164 research outputs found

    Hard macrocells for DC/DC converter in automotive embedded mechatronic systems

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    A novel configurable DC/DC converter architecture, to be integrated as hard macrocell in automotive embedded systems, is proposed in the paper. It aims at realizing an intelligent voltage regulator. With respect to the state of the art, the challenge is the integration into an automotive-qualified chip of several advanced features like dithering of switching frequency, nested control loops with both current and voltage feedback, asynchronous hysteretic control for low power mode, slope control of the power FET gate driver, and diagnostic block against out-of-range current or voltage or temperature conditions. Moreover, the converter macrocell can be connected to the in-vehicle digital network, exchanging with the main vehicle control unit status/diagnostic flags and commands. The proposed design can be configured to work both in step-up and step-down modes, to face a very wide operating input voltage range from 2.5 to 60 V and absolute range from −0.3 to 70 V. The main target is regulating all voltages required in the emerging hybrid/electric vehicles where, besides the conventional 12 V DC bus, also a 48 V DC bus is present. The proposed design supports also digital configurability of the output regulated voltage, through a programmable divider, and of the coefficients of the proportional-integrative controller inside the nested control loops. Fabricated in 0.35 μm CMOS technology, experimental measurements prove that the IC can operate in harsh automotive environments since it meets stringent requirements in terms of electrostatic discharge (ESD) protection, operating temperature range, out-of-range current, or voltage condition

    The conodont genus Teridontus (Miller, 1980) from the Early Ordovician of Montagne Noire, France

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    THE CONODONT genus Teridontus was introduced in 1980 by Miller and was based on the Late Cambrian species Oneotodus nakamurai Nogami, 1967 from the Yencho Member of the Fengshan Fm. of northeast China. Teridontus was later reported from either the Upper Cambrian or Lower Ordovician (Landing et al., 1980; Miller, 1980; Landing and Barnes, 1981; Landing,1983; An et al., 1983, 1985; Ni et al., 1983; Peng et al., 1983; Nowlan, 1985; Landing et al., 1986; Bagnoli et al., 1987; An, 1987; Buggisch and Repetski, 1987; Pohler and Orchard, 1990; An and Zheng, 1990; Seo and Ethington, 1993; Wang, 1993; Lehnert, 1994; Nicoll, 1994; Seo et al., 1994; Ji and Barnes, 1994; Taylor et al., 1996; Lehnert et al., 1997; Jia, 2000; Dubinina, 2000; Pyle and Barnes, 2002; Zeballo et al., 2005) sediments in numerous localities around the world, but a unanimous interpretation of the composition of the Teridontus apparatus organization was far from accepted

    Effect of two gaps on the flux lattice internal field distribution: evidence of two length scales from muSR in Mg1-xAlxB2

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    We have measured the transverse field muon spin precession in the flux lattice (FL) state of the two gap superconductor MgB2 and of the electron doped compounds Mg1-xAlxB2 in magnetic fields up to 2.8T. We show the effect of the two gaps on the internal field distribution in the FL, from which we determine two coherence length parameters and the doping dependence of the London penetration depth. This is an independent determination of the complex vortex structure already suggested by the STM observation of large vortices in a MgB2 single crystal. Our data agrees quantitatively with STM and we thus validate a new phenomenological model for the internal fields.Comment: now in press Phys. Rev. Lett., small modifications required by the edito

    Differential ABC transporter gene expression in adult Dirofilaria immitis males and females following in vitro treatment with ivermectin, doxycycline or a combination of both

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    BACKGROUND: Combination doxycycline/macrocyclic lactone (ML) protocols have been shown to provide a more rapid adulticidal and microfilaricidal effect than either MLs or doxycycline alone, although female worms were reported to have a higher tolerance to treatments compared to male worms. The present study aimed to evaluate how ABC transporters may be involved in the synergic effect of the combination treatment. Adult worms of D. immitis were treated in vitro for 24 hours with doxycycline (DOXY), ivermectin (IVM) and a combination of both, and changes in the modulation of ABC transporter genes were measured. Levels of doxycycline inside different treatment media, post-treatment, were determined through HPLC analysis. RESULTS: Quantitative RT-PCR analysis showed the presence of changes in the modulation of ABC transporter genes evaluated in this study. In particular, in female worms, the combination treatment induced a substantial increase in gene expressions, especially of Dim-pgp-10 and Dim-haf-4; whereas in male worms, the greatest increase in gene expression was observed for Dim-pgp-10 and Dim-pgp-11 when treated with DMSO\u2009+\u2009IVM and DMSO\u2009+\u2009DOXY/IVM. HPLC analysis of the DOXY concentrations in the media after in vitro treatments of male worms showed a slight difference between the DMSO\u2009+\u2009DOXY samples and the combination (DMSO\u2009+\u2009DOXY\u2009+\u2009IVM), while no difference was observed among females. CONCLUSIONS: Further studies are required to explain whether the modulation of cellular efflux plays a role, even partially, in the adulticide effect of doxycycline/macrocyclic lactone combinations in heartworm-infected dogs. To the authors' knowledge, this is the first study to evaluate P-gp expression in adult D. immitis

    Nonequilibrium superconducting thin films with sub-gap and pair-breaking photon illumination

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    We calculate nonequilibrium quasiparticle and phonon distributions for a number of widely-used low transition temperature thin-film superconductors under constant, uniform illumination by sub-gap probe and pair-breaking signal photons simultaneously. From these distributions we calculate material-characteristic parameters that allow rapid evaluation of an effective quasiparticle temperature using a simple analytical expression, for all materials studied (Mo, Al, Ta, Nb, and NbN) for all photon energies. We also explore the temperature and energy-dependence of the low-energy quasiparticle generation efficiency η\eta by pair-breaking signal photons finding η0.6\eta \approx 0.6 in the limit of thick films at low bath temperatures that is material-independent. Taking the energy distribution of excess quasiparticles into account, we find η1\eta \to 1 as the bath temperature approaches the transition temperature in agreement with the assumption of the two-temperature model of the nonequilibrium response that is appropriate in that regime. The behaviour of η\eta with signal frequency scaled by the superconducting energy gap is also shown to be material-independent, and is in qualitative agreement with recent experimental results. An enhancement of η\eta in the presence of sub-gap (probe) photons is shown to be most significant at signal frequencies near the superconducting gap frequency and arises due to multiple photon absorption events that increase the average energy of excess quasiparticles above that in the absence of the probe.This is the author accepted manuscript. The final version is available via IOP Science at http://iopscience.iop.org/0953-2048/28/5/054002/

    11^{11}B NMR study of pure and lightly carbon doped MgB2_2 superconductors

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    We report a 11^{11}B NMR line shape and spin-lattice relaxation rate (1/(T1T)1/(T_1T)) study of pure and lightly carbon doped MgB2x_{2-x}Cx_{x} for x=0x=0, 0.02, and 0.04, in the vortex state and in magnetic field of 23.5 kOe. We show that while pure MgB2_2 exhibits the magnetic field distribution from superposition of the normal and the Abrikosov state, slight replacement of boron with carbon unveils the magnetic field distribution of the pure Abrikosov state. This indicates a considerable increase of Hc2cH_{c2}^c with carbon doping with respect to pure MgB2_2. The spin-lattice relaxation rate 1/(T1T)1/(T_1T) demonstrates clearly the presence of a coherence peak right below TcT_c in pure MgB2_2, followed by a typical BCS decrease on cooling. However, at temperatures lower than 10\approx 10K strong deviation from the BCS behavior is observed, probably from residual contribution of the vortex dynamics. In the carbon doped systems both the coherence peak and the BCS temperature dependence of 1/(T1T)1/(T_1T) weaken, an effect attributed to the gradual shrinking of the σ\sigma hole cylinders of the Fermi surface with electron doping.Comment: 8 pages, 6 figures, submitted to Phys. Rev.
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