29,035 research outputs found

    Bell's inequality and the coincidence-time loophole

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    This paper analyzes effects of time-dependence in the Bell inequality. A generalized inequality is derived for the case when coincidence and non-coincidence [and hence whether or not a pair contributes to the actual data] is controlled by timing that depends on the detector settings. Needless to say, this inequality is violated by quantum mechanics and could be violated by experimental data provided that the loss of measurement pairs through failure of coincidence is small enough, but the quantitative bound is more restrictive in this case than in the previously analyzed "efficiency loophole."Comment: revtex4, 3 figures, v2: epl document class, reformatted w slight change

    A geometric proof of the Kochen-Specker no-go theorem

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    We give a short geometric proof of the Kochen-Specker no-go theorem for non-contextual hidden variables models. Note added to this version: I understand from Jan-Aake Larsson that the construction we give here actually contains the original Kochen-Specker construction as well as many others (Bell, Conway and Kochen, Schuette, perhaps also Peres).Comment: This paper appeared some years ago, before the author was aware of quant-ph. It is relevant to recent developments concerning Kochen-Specker theorem

    How structure of production determines the demand for human capital

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    On the issue of women's status, the objectives of this paper are twofold. First, it attempts to make precise some of the claims and allegations regarding the existence of bias against females in the allocation of resources within the household. The idea is to formulate these questions explicitly, so that it is possible to identify whether and to what degree there is evidence of this bias. Second, it identifies causes of this bias with the objective of isolating key factors that can be used for policy. In contrast to earlier studies that attemptto account for male-female differences in human capital, the authors do not assume any discrimination against females either at home (in the parent's utility function) or in the market (in the returns to human capital). It is assumed, however, that women have a comparative advantage in working in some sectors of the economy. Thus, increases in the shares of these sectors will increase the demand for female human capital. This explicit attention to factors that can be used as policy instruments -- and the relative neglect of factors reflecting gender bias in tastes -- is the point of departure from earlier literature. This paper develops the theory, tests the hypotheses, and concludes with a discussion of the policy implications.Health Monitoring&Evaluation,Economic Theory&Research,Agricultural Knowledge&Information Systems,Housing&Human Habitats,Environmental Economics&Policies

    Is the transition redshift a new cosmological number?

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    Observations from Supernovae Type Ia (SNe Ia) provided strong evidence for an expanding accelerating Universe at intermediate redshifts. This means that the Universe underwent a transition from deceleration to acceleration phases at a transition redshift ztz_t of the order unity whose value in principle depends on the cosmology as well as on the assumed gravitational theory. Since cosmological accelerating models endowed with a transition redshift are extremely degenerated, in principle, it is interesting to know whether the value of ztz_t itself can be observationally used as a new cosmic discriminator. After a brief discussion of the potential dynamic role played by the transition redshift, it is argued that future observations combining SNe Ia, the line-of-sight (or "radial") baryon acoustic oscillations, the differential age of galaxies, as well as the redshift drift of the spectral lines may tightly constrain ztz_t, thereby helping to narrow the parameter space for the most realistic models describing the accelerating Universe.Comment: 12 pages, 5 figures. Some discussions about how to estimate the transition redshift have been added. New data by Planck and H(z) data have been mentioned. New references have been adde

    Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling

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    The relative roles of SULF1 and SULF2 enzymes in tumour growth are controversial, but short SULF1/SULF2 splice variants predominate in human mammary tumours despite their non-detectable levels in normal mammary tissue. Compared with the normal, the level of receptor tyrosine kinase (RTK) activity was markedly increased in triple-positive mammary tumours during later stages of tumour progression showing increased p-EGFR, p-FGFR1 and p-cMet activity in triple-positive but not in triple-negative tumours. The abundance of catalytically inactive short SULF1/SULF2 variants permits high levels of HS sulphation and thus growth driving RTK cell signalling in primary mammary tumours. Also observed in this study, however, was increased N-sulphation detected by antibody 10E4 indicating that not only 6-O sulphation but also N-sulphation may contribute to increased RTK cell signalling in mammary tumours. The levels of such increases in not only SULF1/SULF2 but also in pEGFR, pFGFR1, p-cMet and Smad1/5/8 signalling were further enhanced following lymph node metastasis. The over-expression of Sulf1 and Sulf2 variants in mammary tumour-derived MDA-MB231 and MCF7 cell lines by transfection further confirms Sulf1-/Sulf2-mediated differential modulation of growth. The short variants of both Sulf1 and Sulf2 promoted FGF2-induced MDA-MB231 and MCF7 in vitro growth while full-length Sulf1 inhibited growth supporting in vivo mammary tumour cell signalling patterns of growth. Since a number of mammary tumours become drug resistant to hormonal therapy, Sulf1/Sulf2 inhibition could be an alternative therapeutic approach to target such tumours by down-regulating RTK-mediated cell signalling

    Assessing the cumulative environmental effects of marine renewable energy developments: establishing common ground

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    Assessing and managing the cumulative impacts of human activities on the environment remains a major challenge to sustainable development. This challenge is highlighted by the worldwide expansion of marine renewable energy developments (MREDs) in areas already subject to multiple activities and climate change. Cumulative effects assessments in theory provide decision makers with adequate information about how the environment will respond to the incremental effects of licensed activities and are a legal requirement in many nations. In practise, however, such assessments are beset by uncertainties resulting in substantial delays during the licensing process that reduce MRED investor confidence and limit progress towards meeting climate change targets. In light of these targets and ambitions to manage the marine environment sustainably, reducing the uncertainty surrounding MRED effects and cumulative effects assessment are timely and vital. This review investigates the origins and evolution of cumulative effects assessment to identify why the multitude of approaches and pertinent research have emerged, and discusses key considerations and challenges relevant to assessing the cumulative effects of MREDs and other activities on ecosystems. The review recommends a shift away from the current reliance on disparate environmental impact assessments and limited strategic environmental assessments, and a move towards establishing a common system of coordinated data and research relative to ecologically meaningful areas, focussed on the needs of decision makers tasked with protecting and conserving marine ecosystems and services

    The effects of acceleration stress on human workload and manual control

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    The effects of +Gz stress on operator task performance and workload were assessed. Subjects were presented a two dimensional maze and were required to solve it as rapidly as possible (by moving a light dot through it via a trim switch on a control stick) while under G-stress at levels from +1 Gz to +6 Gz. The G-stress was provided by a human centrifuge. The effects of this stress were assessed by two techniques; (1) objective performance measures on the primary maze-solving task, and (2) subjective workload measures obtained using the subjective workload assessment technique (SWAT). It was found that while neither moderate (+3 Gz) nor high (+5 Gz and +6 Gz) levels of G-stress affected maze solving performance, the high G levels did increase significantly the subjective workload of the maze task
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