240 research outputs found
Interviewer influences on the ratings given values questions by farmers
This thesis is an investigation of interviewer bias. The data upon which this thesis is based were collected from two surveys which were conducted in Bradley and White Counties, Tennessee. A survey was conducted at the beginning and one at the termination of the āTrial-Acre Fertilizer Demonstration and Education Experiment.ā The terminal survey, it was anticipated, would measure the change that had taken place since the experiment was initiated. A brief background of the āTrial-Acreā program is given before the problem of interviewer bias is approached
Effects of leading-edge devices on the low-speed aerodynamic characteristics of a highly-swept arrow-wing
An investigation was conducted in the Texas A&M University 7 by 10 foot Low Speed Wind Tunnel to provide a direct comparison of the effect of several leading edge devices on the aerodynamic performance of a highly swept wing configuration. Analysis of the data indicates that for the configuration with undeflected leading edges, vortex separation first occurs on the outboard wing panel for angles of attack of approximately 2, and wing apex vorticies become apparent for alpha or = 4 deg. However, the occurrence of the leading edge vortex flow may be postponed with leading edge devices. Of the devices considered, the most promising were a simple leading edge deflection of 30 deg and a leading edge slat system. The trailing edge flap effectiveness was found to be essentially the same for the configuration employing either of these more promising leading edge devices. Analysis of the lateral directional data showed that for all of the concepts considered, deflecting leading edge downward in an attempt to postpone leading edge vortex flows, has the favorable effect of reducing the effective dihedral
Insights into oscillator network dynamics using a phase-isostable framework
Networks of coupled nonlinear oscillators can display a wide range of emergent behaviors under the variation of the strength of the coupling. Network equations for pairs of coupled oscillators where the dynamics of each node is described by the evolution of its phase and slowest decaying isostable coordinate have previously been shown to capture bifurcations and dynamics of the network, which cannot be explained through standard phase reduction. An alternative framework using isostable coordinates to obtain higher-order phase reductions has also demonstrated a similar descriptive ability for two oscillators. In this work, we consider the phase-isostable network equations for an arbitrary but finite number of identical coupled oscillators, obtaining conditions required for the stability of phase-locked states including synchrony. For the mean-field complex GinzburgāLandau equation where the solutions of the full system are known, we compare the accuracy of the phase-isostable network equations and higher-order phase reductions in capturing bifurcations of phase-locked states. We find the former to be the more accurate and, therefore, employ this to investigate the dynamics of globally linearly coupled networks of MorrisāLecar neuron models (both two and many nodes). We observe qualitative correspondence between results from numerical simulations of the full system and the phase-isostable description demonstrating that in both small and large networks, the phase-isostable framework is able to capture dynamics that the first-order phase description cannot
Myc stimulates B lymphocyte differentiation and amplifies calcium signaling
Deregulated expression of the Myc family of transcription factors (c-, N-, and L-myc) contributes to the development of many cancers by a mechanism believed to involve the stimulation of cell proliferation and inhibition of differentiation. However, using B cellāspecific c-/N-myc double-knockout mice and EĪ¼-myc transgenic mice bred onto genetic backgrounds (recombinase-activating gene 2ā/ā and Btkā/ā Tecā/ā) whereby B cell development is arrested, we show that Myc is necessary to stimulate both proliferation and differentiation in primary B cells. Moreover, Myc expression results in sustained increases in intracellular Ca2+ ([Ca2+]i), which is required for Myc to stimulate B cell proliferation and differentiation. The increase in [Ca2+]i correlates with constitutive nuclear factor of activated T cells (NFAT) nuclear translocation, reduced Ca2+ efflux, and decreased expression of the plasma membrane Ca2+āadenosine triphosphatase (PMCA) efflux pump. Our findings demonstrate a revised model whereby Myc promotes both proliferation and differentiation, in part by a remarkable mechanism whereby Myc amplifies Ca2+ signals, thereby enabling the concurrent expression of Myc- and Ca2+-regulated target genes
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Chemical composition of air masses transported from Asia to the U.S. West coast during ITCT 2K2: Fossil fuel combustion versus biomass-burning signatures
As part of the Intercontinental Transport and Chemical Transformation experiment in 2002 (ITCT 2K2), a National Oceanic and Atmospheric Administration (NOAA) WP-3D research aircraft was used to study the long-range transport of Asian air masses toward the west coast of North America. During research flights on 5 and 17 May, strong enhancements of carbon monoxide (CO) and other species were observed in air masses that had been transported from Asia. The hydrocarbon composition of the air masses indicated that the highest CO levels were related to fossil fuel use. During the flights on 5 and 17 May and other days, the levels of several biomass-buming indicators increased with altitude. This was true for acetonitrile (CH3CN), methyl chloride (CH3Cl), the ratio of acetylene (C2H2) to propane (C3H8), and, on May 5, the percentage of particles measured by the particle analysis by laser mass spectrometry (PALMS) instrument that were attributed to biomass burning based on their carbon and potassium content. An ensemble of back-trajectories, calculated from the U.S. west coast over a range of latitudes and altitudes for the entire ITCT 2K2 period, showed that air masses from Southeast Asia and China were generally observed at higher altitudes than air from Japan and Korea. Emission inventories estimate the contribution of biomass burning to the total emissions to be low for Japan and Korea, higher for China, and the highest for Southeast Asia. Combined with the origin of the air masses versus altitude, this qualitatively explains the increase with altitude, averaged over the whole ITCT 2K2 period, of the different biomass-burning indicators. Copyright 2004 by the American Geophysical Union
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Gas-phase chemical characteristics of Asian emission plumes observed during ITCT 2K2 over the eastern North Pacific Ocean
The gas-phase chemical characteristics of emission plumes transported from Asia across the Pacific Ocean observed during the Intercontinental Transport and Chemical Transformation experiment in 2002 (ITCT 2K2) are described. Plumes measured in the troposphere from an aircraft were separated from the background air in data analysis using 1-s measurements of carbon monoxide (CO), total reactive nitrogen (NOy), and other gasphase species along with back trajectory analysis. On the basis of these measurements, Asian transport plumes with CO mixing ratios greater than 150 ppbv were observed on seven flights. Correlations between 1-s observations of CO, ozone (O3), and NOy are used to characterize the plumes. The NOy/CO ratios were similar in each plume and significantly lower than those derived from estimated Asian emission ratios, indicating substantial removal of soluble NOy species during transport. Observations of nitric oxide (NO), nitrogen dioxide (NO2) nitric acid (HNO3) peroxyacetyl nitrate (PAN), peroxypropionyl nitrate (PPN), and alkyl nitrates are used with the NOy measurements to further distinguish the transport plumes by their NOy partitioning. NOy was primarily in the form of PAN in plumes that were transported in cold high-latitude and high-altitude regions, whereas in plumes transported in warmer, lower latitude and altitude regions, NOy was mainly HNO3. Additional gas-phase species enhanced in these plumes include sulfuric acid, methanol, acetone, propane, and ethane. The O3/CO ratio varied among the plumes and was affected by the mixing of anthropogenic and stratospheric influences. The complexity of this mixing prevents the determination of the relative contribution of anthropogenic and stratospheric influences to the observed O3 levels. Copyright 2004 by the American Geophysical Union
An investigation of the chemistry of ship emission plumes during ITCT 2002
A ship emission plume experiment was conducted about 100 km off the California coast during the NOAA Intercontinental Transport and Chemical Transformation (ITCT) 2K2 airborne field campaign. Measurements of chemical species were made from the NOAA WP-3D aircraft in eight consecutive transects of a ship plume around midday during 2.5 hours of flight. The measured species include NOx, HNO3, peroxyacetylnitrate (PAN), SO2, H2SO4, O3, CO, CO2, nonmethane hydrocarbons (NMHC), and particle number and size distributions. Observations demonstrate a NOx lifetime of ā¼1.8 hours inside the ship plume compared to ā¼6.5 hours (at noontime) in the moderately polluted background marine boundary layer of the experiment. This confirms the earlier hypothesis of highly enhanced in-plume NOx destruction. Consequently, one would expect the impact of ship emissions is much less severe than those predicted by global models that do not include rapid NOx destruction. Photochemical model calculations suggest that more than 80% of the NOx loss was due to the NO2 + OH reaction; the remainder was by PAN formation. The model underestimated in-plume NOx loss rate by about 30%. In addition, a comparison of measured to predicted H2SO4 in the plumes suggests that the photochemical model predicts OH variability reasonably well but may underestimate actual values. Predictions of in-plume O3 production agree well with the observations, suggesting that model-predicted peroxy radical (HO2 + RO2) levels are reasonable. The model estimated ozone production efficiency ranges from 6 to 30. The largest model bias was seen in the comparison with measured HNO3. The model overestimated in-plume HNO3 by about a factor of 6. This is most likely caused by underestimated HNO3 sinks possibly involving particle scavenging. However, limited data availability precluded a conclusive test of this possible loss process. Copyright 2005 by the American Geophysical Union
Potential Unintended Consequences Due to Medicareās āNo Pay for Errors Ruleā? A Randomized Controlled Trial of an Educational Intervention with Internal Medicine Residents
Medicare has selected 10 hospital-acquired conditions for which it will not reimburse hospitals unless the condition was documented as āpresent on admission.ā This āno pay for errorsā rule may have a profound effect on the clinical practice of physicians.
To determine how physicians might change their behavior after learning about the Medicare rule.
We conducted a randomized trial of a brief educational intervention embedded in an online survey, using clinical vignettes to estimate behavioral changes.
At a university-based internal medicine residency program, 168 internal medicine residents were eligible to participate.
Residents were randomized to receive a one-page description of Medicareās āno pay for errorsā rule with pre-vignette reminders (intervention group) or no information (control group). Residents responded to five clinical vignettes in which āno pay for errorsā conditions might be present on admission.
Primary outcome was selection of the single most clinically appropriate option from three clinical practice choices presented for each clinical vignette.
Survey administered from December 2008 to March 2009. There were 119 responses (71%). In four of five vignettes, the intervention group was less likely to select the most clinically appropriate response. This was statistically significant in two of the cases. Most residents were aware of the rule but not its impact and specifics. Residents acknowledged responsibility to know Medicare documentation rules but felt poorly trained to do so. Residents educated about the Medicareās āno pay for errorsā were less likely to select the most clinically appropriate responses to clinical vignettes. Such choices, if implemented in practice, have the potential for causing patient harm through unnecessary tests, procedures, and other interventions
Inactivation of pyruvate dehydrogenase complex in heart muscle mitochondria of gold-thioglucose-induced obese mice is not due to a stable increase in activity of pyruvate dehydrogenase kinase
Slow escaping points of quasiregular mappings
This article concerns the iteration of quasiregular mappings on Rd and entire functions on C. It is shown that there are always points at which the iterates of a quasiregular map tend to infinity at a controlled rate. Moreover, an asymptotic rate of escape result is proved that is new even for transcendental entire functions. Let f:RdāRd be quasiregular of transcendental type. Using novel methods of proof, we generalise results of Rippon and Stallard in complex dynamics to show that the Julia set of f contains points at which the iterates fn tend to infinity arbitrarily slowly. We also prove that, for any large R, there is a point x with modulus approximately R such that the growth of |fn(x)| is asymptotic to the iterated maximum modulus Mn(R,f)
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