5,108 research outputs found
Radiation Hardness Studies in a CCD with High-Speed Column Parallel Readout
Charge Coupled Devices (CCDs) have been successfully used in several high
energy physics experiments over the past two decades. Their high spatial
resolution and thin sensitive layers make them an excellent tool for studying
short-lived particles. The Linear Collider Flavour Identification (LCFI)
collaboration is developing Column-Parallel CCDs (CPCCDs) for the vertex
detector of the International Linear Collider (ILC). The CPCCDs can be read out
many times faster than standard CCDs, significantly increasing their operating
speed. The results of detailed simulations of the charge transfer inefficiency
(CTI) of a prototype CPCCD are reported and studies of the influence of gate
voltage on the CTI described. The effects of bulk radiation damage on the CTI
of a CPCCD are studied by simulating the effects of two electron trap levels,
0.17 and 0.44 eV, at different concentrations and operating temperatures. The
dependence of the CTI on different occupancy levels (percentage of hit pixels)
and readout frequencies is also studied. The optimal operating temperature for
the CPCCD, where the effects of the charge trapping are at a minimum, is found
to be about 230 K for the range of readout speeds proposed for the ILC. The
results of the full simulation have been compared with a simple analytic model.Comment: 3 pages, 6 figures; presented at IEEE'07, ALCPG'07, ICATPP'0
Nutrients increase epiphyte loads: broad-scale observations and an experimental assessment
The original publication can be found at www.springerlink.comThere is a global trend towards elevated nutrients in coastal waters, especially on human-dominated coasts. We assessed local- to regional-scale relationships between the abundance of epiphytic algae on kelp ( Ecklonia radiata) and nutrient concentrations across much of the temperate coast of Australia, thus assessing the spatial scales over which nutrients may affect benthic assemblages. We tested the hypotheses that (1) percentage cover of epiphytic algae would be greater in areas with higher water nutrient concentrations, and (2) that an experimental enhancement of nutrient concentrations on an oligotrophic coast, to match more eutrophic coasts, would cause an increase in percentage cover of epiphytic algae to match those in more nutrient rich waters. Percentage cover of epiphytes was most extensive around the coast of Sydney, the study location with the greatest concentration of coastal chlorophyll a (a proxy for water nutrient concentration). Elevation of nitrate concentrations at a South Australian location caused an increase in percentage cover of epiphytes that was comparable to percentage covers observed around Sydneyâs coastline. This result was achieved despite our inability to match nutrient concentrations observed around Sydney (<5% of Sydney concentrations), suggesting that increases to nutrient concentrations may have disproportionately larger effects in oligotrophic waters.Bayden D. Russell, Travis S. Elsdon Bronwyn M. Gillanders and Sean D. Connel
First Observation of the Rare Decay Mode K-long -> e+ e-
In an experiment designed to search for and study very rare two-body decay
modes of the K-long, we have observed four examples of the decay K-long -> e+
e-, where the expected background is 0.17+-0.10 events. This observation
translates into a branching fraction of 8.7^{+5.7}_{-4.1} X 10^{-12},
consistent with recent theoretical predictions. This result represents by far
the smallest branching fraction yet measured in particle physics.Comment: 9 pages, 3 figure
Postprandial Diabetic Glucose Tolerance Is Normalized by Gastric Bypass Feeding as Opposed to Gastric Feeding and Is Associated With Exaggerated GLP-1 Secretion: A case report
Evaluation of HIV Protease Inhibitor Use and the Risk of Sudden Death or Nonhemorrhagic Stroke
Concerns have arisen about possible effects of protease inhibitors (PIs) on cardiac conductivity. We found no significant association between current or recent PI exposure and sudden death or nonhemorrhagic stroke (adjusted rate ratio, 1.22; 95% confidence interval, .95-1.57), whereas cumulative exposure to PIs was associated with an increased risk (adjusted rate ratio, 1.06 per year of exposure; 95% confidence interval, 1.01-1.11
Operational experience, improvements, and performance of the CDF Run II silicon vertex detector
The Collider Detector at Fermilab (CDF) pursues a broad physics program at
Fermilab's Tevatron collider. Between Run II commissioning in early 2001 and
the end of operations in September 2011, the Tevatron delivered 12 fb-1 of
integrated luminosity of p-pbar collisions at sqrt(s)=1.96 TeV. Many physics
analyses undertaken by CDF require heavy flavor tagging with large charged
particle tracking acceptance. To realize these goals, in 2001 CDF installed
eight layers of silicon microstrip detectors around its interaction region.
These detectors were designed for 2--5 years of operation, radiation doses up
to 2 Mrad (0.02 Gy), and were expected to be replaced in 2004. The sensors were
not replaced, and the Tevatron run was extended for several years beyond its
design, exposing the sensors and electronics to much higher radiation doses
than anticipated. In this paper we describe the operational challenges
encountered over the past 10 years of running the CDF silicon detectors, the
preventive measures undertaken, and the improvements made along the way to
ensure their optimal performance for collecting high quality physics data. In
addition, we describe the quantities and methods used to monitor radiation
damage in the sensors for optimal performance and summarize the detector
performance quantities important to CDF's physics program, including vertex
resolution, heavy flavor tagging, and silicon vertex trigger performance.Comment: Preprint accepted for publication in Nuclear Instruments and Methods
A (07/31/2013
A straw drift chamber spectrometer for studies of rare kaon decays
We describe the design, construction, readout, tests, and performance of
planar drift chambers, based on 5 mm diameter copperized Mylar and Kapton
straws, used in an experimental search for rare kaon decays. The experiment
took place in the high-intensity neutral beam at the Alternating Gradient
Synchrotron of Brookhaven National Laboratory, using a neutral beam stop, two
analyzing dipoles, and redundant particle identification to remove backgrounds
Characterisation of the key determinants of Phd antitoxin mediated Doc toxin inactivation in Salmonella
In the search for novel antimicrobial therapeutics, toxin-antitoxin (TA) modules are promising yet underexplored targets for overcoming antibiotic failure. The bacterial toxin Doc has been associated with the persistence of Salmonella in macrophages, enabling its survival upon antibiotic exposure. After developing a novel method to produce the recombinant toxin, we have used antitoxin-mimicking peptides to thoroughly investigate the mechanism by which its cognate antitoxin Phd neutralizes the activity of Doc. We reveal insights into the molecular detail of the PhdâDoc relationship and discriminate antitoxin residues that stabilize the TA complex from those essential for inhibiting the activity of the toxin. Coexpression of Doc and antitoxin peptides in Salmonella was able to counteract the activity of the toxin, confirming our in vitro results with equivalent sequences. Our findings provide key principles for the development of chemical tools to study and therapeutically interrogate this important class of proteinâprotein interactions
Loss of heterozygosity at 9q33 and hypermethylation of the DBCCR1 gene in oral squamous cell carcinoma
Search for the Weak Decay of an H Dibaryon
We have searched for a neutral dibaryon decaying via and
. Our search has yielded two candidate events from which we set
an upper limit on the production cross section. Normalizing to the
inclusive production cross section, we find at 90% C.L., for an of mass
2.15 GeV/.Comment: 11 pages, 6 postscript figures, epsfig, aps, preprint, revte
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