1,173 research outputs found
Quantum teleportation of EPR pair by three-particle entanglement
Teleportation of an EPR pair using triplet in state of the
Horne-Greenberger-Zeilinger form to two receivers is considered. It needs a
three-particle basis for joint measurement. By contrast the one qubit
teleportation the required basis is not maximally entangled. It consists of the
states corresponding to the maximally entanglement of two particles only. Using
outcomes of measurement both receivers can recover an unknown EPR state however
one of them can not do it separately. Teleportation of the N-particle
entanglement is discussed.Comment: 7 pages, LaTeX, 3 figure
Influence of Spin Wave Excitations on the Ferromagnetic Phase Diagram in the Hubbard-Model
The subject of the present paper is the theoretical description of collective
electronic excitations, i.e. spin waves, in the Hubbard-model. Starting with
the widely used Random-Phase-Approximation, which combines Hartree-Fock theory
with the summation of the two-particle ladder, we extend the theory to a more
sophisticated single particle approximation, namely the
Spectral-Density-Ansatz. Doing so we have to introduce a `screened`
Coulomb-interaction rather than the bare Hubbard-interaction in order to obtain
physically reasonable spinwave dispersions. The discussion following the
technical procedure shows that comparison of standard RPA with our new
approximation reduces the occurrence of a ferromagnetic phase further with
respect to the phase-diagrams delivered by the single particle theories.Comment: 8 pages, 9 figures, RevTex4, accepted for publication in Phys. Rev.
The Influence of Polygenic Risk Scores on Heritability of Anti-CCP Level in RA
Objective: To study genetic factors that influence quantitative anti-cyclic citrullinated peptide (anti-CCP) antibody levels in RA patients. Methods: We carried out a genome wide association study (GWAS) meta-analysis using 1,975 anti-CCP+ RA patients from 3 large cohorts, the Brigham Rheumatoid Arthritis Sequential Study (BRASS), North American Rheumatoid Arthritis Consortium (NARAC), and the Epidemiological Investigation of RA (EIRA). We also carried out a genome-wide complex trait analysis (GCTA) to estimate the heritability of anti-CCP levels. Results: GWAS-meta analysis showed that anti-CCP levels were most strongly associated with the human leukocyte antigen (HLA) region with a p-value of 2×10−11 for rs1980493. There were 112 SNPs in this region that exceeded the genome-wide significance threshold of 5×10−8, and all were in linkage disequilibrium (LD) with the HLA- DRB1*03 allele with LD r2 in the range of 0.25-0.88. Suggestive novel associations outside of the HLA region were also observed for rs8063248 (near the GP2 gene) with a p-value of 3×10−7. None of the known RA risk alleles (~52 loci) were associated with anti-CCP level. Heritability analysis estimated that 44% of anti-CCP variation was attributable to genetic factors captured by GWAS variants. Conclusions: Anti-CCP level is a heritable trait. HLA-DR3 and GP2 are associated with lower anti-CCP levels
Do contaminants originating from state-of-the-art treated wastewater impact the ecological quality of surface waters?
Since the 1980s, advances in wastewater treatment technology have led to considerably improved surface water quality in the urban areas of many high income countries. However, trace concentrations of organic wastewater-associated contaminants may still pose a key environmental hazard impairing the ecological quality of surface waters. To identify key impact factors, we analyzed the effects of a wide range of anthropogenic and environmental variables on the aquatic macroinvertebrate community. We assessed ecological water quality at 26 sampling sites in four urban German lowland river systems with a 0–100% load of state-of-the-art biological activated sludge treated wastewater. The chemical analysis suite comprised 12 organic contaminants (five phosphor organic flame retardants, two musk fragrances, bisphenol A, nonylphenol, octylphenol, diethyltoluamide, terbutryn), 16 polycyclic aromatic hydrocarbons, and 12 heavy metals. Non-metric multidimensional scaling identified organic contaminants that are mainly wastewater-associated (i.e., phosphor organic flame retardants, musk fragrances, and diethyltoluamide) as a major impact variable on macroinvertebrate species composition. The structural degradation of streams was also identified as a significant factor. Multiple linear regression models revealed a significant impact of organic contaminants on invertebrate populations, in particular on Ephemeroptera, Plecoptera, and Trichoptera species. Spearman rank correlation analyses confirmed wastewater-associated organic contaminants as the most significant variable negatively impacting the biodiversity of sensitive macroinvertebrate species. In addition to increased aquatic pollution with organic contaminants, a greater wastewater fraction was accompanied by a slight decrease in oxygen concentration and an increase in salinity. This study highlights the importance of reducing the wastewater-associated impact on surface waters. For aquatic ecosystems in urban areas this would lead to: (i) improvement of the ecological integrity, (ii) reduction of biodiversity loss, and (iii) faster achievement of objectives of legislative requirements, e.g., the European Water Framework Directive
Hyperon weak radiative decays in chiral perturbation theory
We investigate the leading-order amplitudes for weak radiative decays of
hyperons in chiral perturbation theory. We consistently include contributions
from the next-to-leading order weak-interaction Lagrangian. It is shown that
due to these terms Hara's theorem is violated. The data for the decays of
charged hyperons can be easily accounted for. However, at this order in the
chiral expansion, the four amplitudes for the decays of neutral hyperons
satisfy relations which are in disagreement with the data. The asymmetry
parameters for all the decays can not be accounted for without higher-order
terms. We shortly comment on the effect of the 27-plet part of the weak
interaction.Comment: 8 pages of REVTeX and using macro-package "feynman.tex" (available at
http://xxx.lanl.gov/ftp/hep-ph/papers/macros) for the 2 figure
A Stronger Innate Immune Response During Hyperacute Human Immunodeficiency Virus Type 1 (HIV-1) Infection Is Associated With Acute Retroviral Syndrome
Background: Acute retroviral syndrome (ARS) is associated with human immunodeficiency virus type 1 (HIV-1) subtype and disease progression, but the underlying immunopathological pathways are poorly understood. We aimed to elucidate associations between innate immune responses during hyperacute HIV-1 infection (hAHI) and ARS. // Methods: Plasma samples obtained from volunteers (≥18.0 years) before and during hAHI, defined as HIV-1 antibody negative and RNA or p24 antigen positive, from Kenya, Rwanda, Uganda, Zambia, and Sweden were analyzed. Forty soluble innate immune markers were measured using multiplexed assays. Immune responses were differentiated into volunteers with stronger and comparatively weaker responses using principal component analysis. Presence or absence of ARS was defined based on 11 symptoms using latent class analysis. Logistic regression was used to determine associations between immune responses and ARS. // Results: Of 55 volunteers, 31 (56%) had ARS. Volunteers with stronger immune responses (n = 36 [65%]) had increased odds of ARS which was independent of HIV-1 subtype, age, and risk group (adjusted odds ratio, 7.1 [95% confidence interval {CI}: 1.7–28.8], P = .003). Interferon gamma-induced protein (IP)-10 was 14-fold higher during hAHI, elevated in 7 of the 11 symptoms and independently associated with ARS. IP-10 threshold >466.0 pg/mL differentiated stronger immune responses with a sensitivity of 84.2% (95% CI: 60.4–96.6) and specificity of 100.0% (95% CI]: 90.3–100.0). //
Conclusions: A stronger innate immune response during hAHI was associated with ARS. Plasma IP-10 may be a candidate biomarker of stronger innate immunity. Our findings provide further insights on innate immune responses in regulating ARS and may inform the design of vaccine candidates harnessing innate immunity
Darwin -— an experimental astronomy mission to search for extrasolar planets
As a response to ESA call for mission concepts for its Cosmic Vision 2015–2025 plan, we propose a mission called Darwin. Its primary goal is the study of terrestrial extrasolar planets and the search for life on them. In this paper, we describe different characteristics of the instrument
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