2,572 research outputs found
The psychometric properties of the CFSS-DS for schoolchildren in Saudi Arabia:a confirmatory factor analytic approach
Aim to test the psychometric properties of an Arabic version of the Child Fear Survey ScheduleâDental Subscale (CFSSâDS) a using confirmatory factor analysis. Methods 2 convenience samples were obtained: Sample [1]: 600 boys (33%) and girls attending 4 public schools in Onizah and Sample [2] 800 girls attending 8 public schools in Buridah. The questionnaire asked the participant's age, gender and completion of the CFSSâDS. The data were subjected to exploratory factor analysis (EFA), parallel factor analysis, Cronbach alpha, confirmatory factor analysis (CFA) and goodness of fit statistics. Results 513 children in Sample [1] and 503 children in Sample [2] participated giving a valid response rate of 86% and 67% respectively. From the EFA 3 factors were identified and confirmed statistically using parallel factor analysis. The internal consistency of the 3âfactors, dental fear subscale (0.86); hospital fear subscale (0.77) and stranger fear subscale (0.71) was good. The CFA showed that the current EFA model was an equivalent fit to the El Housseiny et al1 model, however, the solution using El Housseiny et al's structure was distorted. Conclusions A 3âfactor structure with acceptable reliability exists for this Arabic version of the CFSSâDS, confirmed by a CFA using an additional data set.PostprintPeer reviewe
How standard is standard care? Exploring control group outcomes in behaviour change interventions for young people with type 1 diabetes
Objective: Poor descriptions of standard care may compromise interpretation of results in randomised controlled trials (RCTs) of health interventions. We investigated quality of standard care in RCTs of behaviour change interventions for young people with type 1 diabetes and consider implications for evaluating trial outcomes.
Design: We conducted systematic searches for articles published between 1999 and 2012. We extracted standard care descriptions and contacted trial authors to complete a checklist of standard care activities. The relationship between standard care quality and outcomes was examined via subgroup meta-analyses and meta-regression.
Main outcome measures: Standard care descriptions, standard care quality, and relationships between standard care quality with medical and psychological outcomes.
Results: We identified 20 RCTs described across 26 articles. Published descriptions of standard care were limited to service-level features. Author responses indicated standard care provision extended beyond published accounts. Subgroup analyses suggested control groups receiving higher standard care quality showed larger improvements in both medical and psychological outcomes, although standard care quality did not predict outcomes significantly.
Conclusion: The quality of care delivered to control group participants can influence outcomes of RCTs. Inadequate reporting exacerbates this issue by masking variations between trials. We argue for increased clarity in reporting standard care in future trials
Educational outcomes in extremely preterm children : neuropsychological correlates and predictors of attainment
This study assessed the impact of extremely preterm birth on academic attainment at 11 years of
age, investigated neuropsychological antecedents of attainment in reading and mathematics, and
examined early predictors of educational outcomes. Children born extremely preterm had significantly
poorer academic attainment and a higher prevalence of learning difficulties than their term
peers. General cognitive ability and specific deficits in visuospatial skills or phoneme deletion at 6
years were predictive of mathematics and reading attainment at 11 years in both extremely preterm
and term children. Phonological processing, attention, and executive functions at 6 years were also
associated with academic attainment in children born extremely preterm. Furthermore, social factors,
neonatal factors (necrotizing enterocolitis, breech delivery, abnormal cerebral ultrasound, early
breast milk provision), and developmental factors at 30 months (head circumference, cognitive development),
were independent predictors of educational outcomes at 11 years. Neonatal complications
combined with assessments of early cognitive function provide moderate prediction for educational
outcomes in children born extremely preterm
Framing and signalling effects of taxes on sugary drinks: a discrete choice experiment among households in Great Britain
Taxes on sugar-sweetened beverages (SSBs) are in place in many countries to combat obesity with emerging evidence that these are effective in reducing purchases of SSBs. In this study, we tested whether signalling and framing the price increase from an SSB tax explicitly as a health-related, earmarked measure reduces the demand for SSBs more than an equivalent price increase. We measured the demand for non-alcoholic beverages with a discrete choice experiment (DCE) administered online to a randomly selected group of n = 603 households with children in Great Britain (GB) who regularly purchase SSBs. We find a suggestive evidence that a price increase leads to a larger reduction in the probability of choosing SSBs when it is signalled as a tax and framed as a health-related and earmarked policy. Respondents who did not support a tax on SSBs, who were also more likely to choose SSBs in the first place, were on average more responsive to a price increase framed as an earmarked tax than those who supported the tax. The predictive validity of the DCE, to capture preferences for beverages, was confirmed using actual purchase data. The findings imply that a well-signalled and earmarked tax on SSBs could improve its effectiveness at reducing the demand
Physical activity and health related quality of life
Copyright @ 2012 Anokye et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.This article has been made available through the Brunel Open Access Publishing Fund.BACKGROUND: Research on the relationship between Health Related Quality of Life (HRQoL) and physical activity (PA), to date, have rarely investigated how this relationship differ across objective and subjective measures of PA. The aim of this paper is to explore the relationship between HRQoL and PA, and examine how this relationship differs across objective and subjective measures of PA, within the context of a large representative national survey from England. METHODS: Using a sample of 5,537 adults (40â60âyears) from a representative national survey in England (Health Survey for England 2008), Tobit regressions with upper censoring was employed to model the association between HRQoL and objective, and subjective measures of PA controlling for potential confounders. We tested the robustness of this relationship across specific types of PA. HRQoL was assessed using the summary measure of health state utility value derived from the EuroQol-5 Dimensions (EQ-5D) whilst PA was assessed via subjective measure (questionnaire) and objective measure (accelerometer- actigraph model GT1M). The actigraph was worn (at the waist) for 7âdays (during waking hours) by a randomly selected sub-sample of the HSE 2008 respondents (4,507 adults â 16 plus years), with a valid day constituting 10 hours. Analysis was conducted in 2010. RESULTS: Findings suggest that higher levels of PA are associated with better HRQoL (regression coefficient: 0.026 to 0.072). This relationship is consistent across different measures and types of PA although differences in the magnitude of HRQoL benefit associated with objective and subjective (regression coefficient: 0.047) measures of PA are noticeable, with the former measure being associated with a relatively better HRQoL (regression coefficient: 0.072). CONCLUSION: Higher levels of PA are associated with better HRQoL. Using an objective measure of PA compared with subjective shows a relatively better HRQoL.This project was funded by the NIHR Health Technology Assessment programme (project number 08/72/01)
Anxiety and anxious-depression in Parkinson's disease over a 4-year period: A latent transition analysis
Background: Depression and anxiety in Parkinson's disease are common and frequently co-morbid, with significant impact on health outcome. Nevertheless, management is complex and often suboptimal. The existence of clinical subtypes would support stratified approaches in both research and treatment.
Method: Five hundred and thirteen patients with Parkinson's disease were assessed annually for up to 4 years. Latent transition analysis (LTA) was used to identify classes that may conform to clinically meaningful subgroups, transitions between those classes over time, and baseline clinical and demographic features that predict common trajectories.
Results: In total, 64.1% of the sample remained in the study at year 4. LTA identified four classes, a 'Psychologically healthy' class (approximately 50%), and three classes associated with psychological distress: one with moderate anxiety alone (approximately 20%), and two with moderate levels of depression plus moderate or severe anxiety. Class membership tended to be stable across years, with only about 15% of individuals transitioning between the healthy class and one of the distress classes. Stable distress was predicted by higher baseline depression and psychiatric history and younger age of onset of Parkinson's disease. Those with younger age of onset were also more likely to become distressed over the course of the study.
Conclusions: Psychopathology was characterized by relatively stable anxiety or anxious-depression over the 4-year period. Anxiety, with or without depression, appears to be the prominent psychopathological phenotype in Parkinson's disease suggesting a pressing need to understanding its mechanisms and improve management
The effects of social service contact on teenagers in England
Objective: This study investigated outcomes of social service contact during teenage years.
Method: Secondary analysis was conducted of the Longitudinal Survey of Young People in England (N = 15,770), using data on reported contact with social services resulting from teenagersâ behavior. Outcomes considered were educational achievement and aspiration, mental health, and locus of control. Inverse-probability-weighted regression adjustment was used to estimate the effect of social service contact.
Results: There was no significant difference between those who received social service contact and those who did not for mental health outcome or aspiration to apply to university. Those with contact had lower odds of achieving good exam results or of being confident in university acceptance if sought. Results for locus of control were mixed.
Conclusions: Attention is needed to the role of social services in supporting the education of young people in difficulty. Further research is needed on the outcomes of social services contact
Treatment compliance and effectiveness of a cognitive behavioural intervention for low back pain : a complier average causal effect approach to the BeST data set
Background:
Group cognitive behavioural intervention (CBI) is effective in reducing low-back pain and disability in comparison to advice in primary care. The aim of this analysis was to investigate the impact of compliance on estimates of treatment effect and to identify factors associated with compliance.
Methods:
In this multicentre trial, 701 adults with troublesome sub-acute or chronic low-back pain were recruited from 56 general practices. Participants were randomised to advice (control nâ=â233) or advice plus CBI (nâ=â468). Compliance was specified a priori as attending a minimum of three group sessions and the individual assessment. We estimated the complier average causal effect (CACE) of treatment.
Results:
Comparison of the CACE estimate of the mean treatment difference to the intention-to-treat (ITT) estimate at 12 months showed a greater benefit of CBI amongst participants compliant with treatment on the Roland Morris Questionnaire (CACE: 1.6 points, 95% CI 0.51 to 2.74; ITT: 1.3 points, 95% CI 0.55 to 2.07), the Modified Von Korff disability score (CACE: 12.1 points, 95% CI 6.07 to 18.17; ITT: 8.6 points, 95% CI 4.58 to 12.64) and the Modified von Korff pain score (CACE: 10.4 points, 95% CI 4.64 to 16.10; ITT: 7.0 points, 95% CI 3.26 to 10.74). People who were non-compliant were younger and had higher pain scores at randomisation.
Conclusions:
Treatment compliance is important in the effectiveness of group CBI. Younger people and those with more pain are at greater risk of non-compliance
The substantive and practical significance of citation impact differences between institutions: Guidelines for the analysis of percentiles using effect sizes and confidence intervals
In our chapter we address the statistical analysis of percentiles: How should
the citation impact of institutions be compared? In educational and
psychological testing, percentiles are already used widely as a standard to
evaluate an individual's test scores - intelligence tests for example - by
comparing them with the percentiles of a calibrated sample. Percentiles, or
percentile rank classes, are also a very suitable method for bibliometrics to
normalize citations of publications in terms of the subject category and the
publication year and, unlike the mean-based indicators (the relative citation
rates), percentiles are scarcely affected by skewed distributions of citations.
The percentile of a certain publication provides information about the citation
impact this publication has achieved in comparison to other similar
publications in the same subject category and publication year. Analyses of
percentiles, however, have not always been presented in the most effective and
meaningful way. New APA guidelines (American Psychological Association, 2010)
suggest a lesser emphasis on significance tests and a greater emphasis on the
substantive and practical significance of findings. Drawing on work by Cumming
(2012) we show how examinations of effect sizes (e.g. Cohen's d statistic) and
confidence intervals can lead to a clear understanding of citation impact
differences
An exploratory cluster randomised controlled trial of knowledge translation strategies to support evidence-informed decision-making in local governments (The KT4LG study)
Background: Childhood overweight and obesity is the most prevalent and, arguably, politically complex child health problem internationally. Governments, communities and industry have important roles to play, and are increasingly expected to deliver an evidence-informed system-wide prevention program. However, efforts are impeded by a lack of organisational access to and use of research evidence. This study aims to identify feasible, acceptable and ideally, effective knowledge translation (KT) strategies to increase evidence-informed decision making in local governments, within the context of childhood obesity prevention as a national policy priority.Methods/Design: This paper describes the methods for KT4LG, a cluster randomised controlled trial which is exploratory in nature, given the limited evidence base and methodological advances. KT4LG aims to examine a program of KT strategies to increase the use of research evidence in informing public health decisions in local governments. KT4LG will also assess the feasibility and acceptability of the intervention. The intervention program comprises a facilitated program of evidence awareness, access to tailored research evidence, critical appraisal skills development, networking and evidence summaries and will be compared to provision of evidence summaries alone in the control program. 28 local governments were randomised to intervention or control, using computer generated numbers, stratified by budget tertile (high, medium or low). Questionnaires will be used to measure impact, costs, and outcomes, and key informant interviews will be used to examine processes, feasibility, and experiences. Policy tracer studies will be included to examine impact of intervention on policies within relevant government policy documents.Discussion: Knowledge translation intervention studies with a focus on public health and prevention are very few in number. Thus, this study will provide essential data on the experience of program implementation and evaluation of a system-integrated intervention program employed within the local government public health context. Standardised programs of system, organisational and individual KT strategies have not been described or rigorously evaluated. As such, the findings will make a significant contribution to understanding whether a facilitated program of KT strategies hold promise for facilitating evidence-informed public health decision making within complex multisectoral government organisations.<br /
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