29 research outputs found
Prioritized Repairing and Consistent Query Answering in Relational Databases
A consistent query answer in an inconsistent database is an answer obtained
in every (minimal) repair. The repairs are obtained by resolving all conflicts
in all possible ways. Often, however, the user is able to provide a preference
on how conflicts should be resolved. We investigate here the framework of
preferred consistent query answers, in which user preferences are used to
narrow down the set of repairs to a set of preferred repairs. We axiomatize
desirable properties of preferred repairs. We present three different families
of preferred repairs and study their mutual relationships. Finally, we
investigate the complexity of preferred repairing and computing preferred
consistent query answers.Comment: Accepted to the special SUM'08 issue of AMA
Schemas for Unordered XML on a DIME
We investigate schema languages for unordered XML having no relative order
among siblings. First, we propose unordered regular expressions (UREs),
essentially regular expressions with unordered concatenation instead of
standard concatenation, that define languages of unordered words to model the
allowed content of a node (i.e., collections of the labels of children).
However, unrestricted UREs are computationally too expensive as we show the
intractability of two fundamental decision problems for UREs: membership of an
unordered word to the language of a URE and containment of two UREs.
Consequently, we propose a practical and tractable restriction of UREs,
disjunctive interval multiplicity expressions (DIMEs).
Next, we employ DIMEs to define languages of unordered trees and propose two
schema languages: disjunctive interval multiplicity schema (DIMS), and its
restriction, disjunction-free interval multiplicity schema (IMS). We study the
complexity of the following static analysis problems: schema satisfiability,
membership of a tree to the language of a schema, schema containment, as well
as twig query satisfiability, implication, and containment in the presence of
schema. Finally, we study the expressive power of the proposed schema languages
and compare them with yardstick languages of unordered trees (FO, MSO, and
Presburger constraints) and DTDs under commutative closure. Our results show
that the proposed schema languages are capable of expressing many practical
languages of unordered trees and enjoy desirable computational properties.Comment: Theory of Computing System
Enhancing the water capacity in Zr-based metal-organic framework for heat pump and atmospheric water generator applications
\u3cp\u3eAccording to the European Commission, in 2016 the residential sector represented 25.4% of the final energy consumption. Heating and cooling in EU households account for 69.1% of the total energy consumption. The fraction of 84% for heating and cooling is still generated from fossil fuels, and only 16% is generated from renewable energy. To decrease carbon dioxide emissions of fossil fuel consumption, it is crucial to find alternatives to supply the heating and cooling demand. Alternatives such as adsorption-based heat pumps and desiccant cooling systems are receiving much attention because of their moderate energy consumption. These systems are based on the energetic exchange during the adsorption/desorption of working fluids. In this work, we combined experiments and simulations to evaluate the viability of several zeolites and MOFs with water for cooling systems applications. We combined the study of adsorption mechanisms and the dynamics of water inside the pores of the structures, thereby obtaining an overall understanding of the working pair. We found that the Al content in FAU-topology zeolites is a key factor for an efficient process. We also identify ZJNU-30 metal-organic framework as a suitable candidate for cooling applications because of its outstanding water capacity, cooling capacity, and coefficient of performance.\u3c/p\u3
π-Complexation for olefin/paraffin separation using aluminosilicates
International audienc
Enhancing the Water Capacity in Zr-Based Metal–Organic Framework for Heat Pump and Atmospheric Water Generator Applications
According to the European Commission, in 2016 the residential sector represented 25.4% of the final energy consumption. Heating and cooling in EU households account for 69.1% of the total energy consumption. The fraction of 84% for heating and cooling is still generated from fossil fuels, and only 16% is generated from renewable energy. To decrease carbon dioxide emissions of fossil fuel consumption, it is crucial to find alternatives to supply the heating and cooling demand. Alternatives such as adsorption-based heat pumps and desiccant cooling systems are receiving much attention because of their moderate energy consumption. These systems are based on the energetic exchange during the adsorption/desorption of working fluids. In this work, we combined experiments and simulations to evaluate the viability of several zeolites and MOFs with water for cooling systems applications. We combined the study of adsorption mechanisms and the dynamics of water inside the pores of the structures, thereby obtaining an overall understanding of the working pair. We found that the Al content in FAU-topology zeolites is a key factor for an efficient process. We also identify ZJNU-30 metal–organic framework as a suitable candidate for cooling applications because of its outstanding water capacity, cooling capacity, and coefficient of performance.Accepted Author ManuscriptEngineering Thermodynamic
SCENIC: single-cell regulatory network inference and clustering
We present SCENIC, a computational method for simultaneous gene regulatory network reconstruction and cell-state identification from single-cell RNA-seq data (http://scenic.aertslab.org). On a compendium of single-cell data from tumors and brain, we demonstrate that cis-regulatory analysis can be exploited to guide the identification of transcription factors and cell states. SCENIC provides critical biological insights into the mechanisms driving cellular heterogeneity
Clinical variability of neuroacanthocytosis syndromes : A series of six patients with long follow-up
Objective To provide clinical clues to differential diagnosis in patients with chorea and other movement disorders with blood acanthocytes. Methods We present a long-term video accompanied follow-up of six Caucasian patients with neuroacanthocytosis from several centers, three diagnosed with chorea-acanthocytosis (ChAc): 34-y.o.(no.1), 36-y.o.(no.2), 43-y.o.(no.3), two diagnosed with McLeod Syndrome (MLS): 52-y.o.(no.4), 61-y.o.(no.5) and one 63-y.o.(no.6), a brother of no.5, with clinical suspicion of MLS. Additionally we report pathological findings of the mother of two brothers with MLS reported in our series with acanthocytes on peripheral blood smear Results The patients had an unremarkable family history and were asymptomatic until adulthood. Patients no. 1,2,4,5,6 developed generalized chorea and patient no. 3 had predominant bradykinesia. Patients no. 1,2,3 had phonic and motor tics, additionally patients no. 1 and 2 exhibited peculiar oromandibular dystonia with tongue thrusting. In patients no. 2 and 3 dystonic supination of feet was observed, patient no. 3 subsequently developed bilateral foot drop. Patients no. 2 and 4 had signs of muscle atrophy. Tendon reflexes were decreased or absent and electroneurography demonstrated sensorimotor neuropathy in patients no. 1,2,3,4,5, except no. 6. Generalized seizures were seen in patients no. 2,3,5,6 and myoclonic jerks in patient no. 1. Cognitive deterioration was reported in patients no. 1,2,3,5,6. Serum creatine kinase levels were elevated in all six patients. Conclusion We highlight the variability of clinical presentation of neuroacanthocytosis syndromes and the long time from the onset to diagnosis with the need to screen the blood smears in uncertain cases, however, as in one of our cases acanthocytes may even be not found. Based on our observations and data from the literature we propose several red flags that should raise the suspicion of an NA syndrome in a patient with a movement disorder: severe orofacial dyskinesia with tongue and lip-biting (typical of ChAc), feeding dystonia, psychiatric and cognitive disturbances, seizures, peripheral neuropathy, elevation of creatine kinase, elevation of transaminases, hepatosplenomegaly, cardiomyopathy and arrhythmias, and an X-linked pattern of inheritance (McLeod Syndrome, MLS)