Krull Dimension of Tame Generalized Multicoil Algebras

We determine the Krull dimension of the module category of finite dimensional tame generalized multicoil algebras over an algebraically closed field, which are domestic

The role of endothelial cilia in post-embryonic vascular development

BACKGROUND: Cilia are essential for morphogenesis and maintenance of many tissues. Loss-of-function of cilia in early zebrafish development causes a range of vascular defects including cerebral haemorrhage and reduced arterial vascular mural cell coverage. In contrast, loss of endothelial cilia in mice has little effect on vascular development. We therefore used a conditional rescue approach to induce endothelial cilia ablation after early embryonic development and examined the effect on vascular development and mural cell development in post-embryonic, juvenile and adult zebrafish. RESULTS: ift54(elipsa) mutant zebrafish are unable to form cilia. We rescued cilia formation and ameliorated the phenotype of ift54 mutants using a novel Tg(ubi:loxP-ift54-loxP-myr-mcherry,myl7:EGFP)sh488 transgene expressing wildtype ift54 flanked by recombinase sites, then used a Tg(kdrl:cre)s898 transgene to induce endothelial-specific inactivation of ift54 at post-embryonic ages. Fish without endothelial ift54 function could survive to adulthood and exhibited no vascular defects. Endothelial inactivation of ift54 did not affect development of tagln-positive vascular mural cells around either the aorta or the caudal fin vessels, nor formation of vessels after tailfin resection in adult animals. CONCLUSIONS: Endothelial cilia are not essential for development and remodelling of the vasculature in juvenile and adult zebrafish when inactivated after embryogenesis

Cycle-finite module categories

We describe the structure of module categories of finite dimensional algebras over an algebraically closed field for which the cycles of nonzero nonisomorphisms between indecomposable finite dimensional modules are finite (do not belong to the infinite Jacobson radical of the module category). Moreover, geometric and homological properties of these module categories are exhibited

Effectiveness of „mobile” and stationary X-ray units and computed tomography in brachytherapy treatment planning

CT, mobile and stationary x-ray cameras were used with the aim of comparing the source localization effectiveness in brachytherapy planning. Properties of orthogonal X-ray pictures were discussed and their impact on dose planning in brachytherapy was evaluated.Differences between doses calculated for applicator positions localized by stationary and „mobile” X-ray units ranged between 6% and 11% in the rectum and 10% in the bladder, respectively

56 Efektywność elektronicznego obrazowania napromienianego pola w kontroli jakości radioterapii

Celem pracy jest ocena jakości i efektywności elektronicznego systemu portal imaging (EPID) z możliwością cyfrowego ulepszenia i analizowania otrzymanych obrazów w kontroli jakości radioterapii.Elektroniczne zdjęcia weryfikacyjne wykonano przed rozpoczęciem leczenia u 57% (97/170) napromienianych chorych. Procedura wykonywania djęć weryfikacyjnych przedłuża czas pojedynczej sesji napromieniania o 10% – 20% (1–2 minut). 87% z otrzymanych zdjęć elektronicznych nadawało się do oceny pod względem jakościowym. U 20% (19/97) chorych monitorowanych przy pomocy EPID wprowadzono poprawki przed rozpoczęciem napromieniania na podstawie zdjęć weryfikacyjnych.W monitorowanej grupie tygodniowe zdjęcia weryfikacyjne wykonano 78% napromienianych chorych. Codzienne zdjęcia weryfikacyjne z seriami zdjęć w trakcie napromieniania chorych. Różne błędy zostały zarejestrowane u 33% monitorowanych chorych w trakcie radioterapii. Większość błędów została skorygowana w trakcie leczenia, niektóre zostały zauważone podczas analizy po zakończeniu napromieniania. Zarejestrowano 2132 zdjęć elektronicznych do dalszej analizy. Target View umożliwia weryfikowanie poprawności leczenia u większości leczonych chorych bez zmniejszenia liczby napromienianych pacjentów. Otrzymane zdjęcia elektroniczne są dobrej jakości, co umożliwia zarejestrowanie i korekcję różnych błędów geometrycznych przed rozpoczęciem i w trakcie leczenia.Zarejestrowane zdjęcia elektroniczne mogą być precyzyjnie analizowane poprzez nakładanie na siebie i pomiary zauważonych rozbieżności w celu poprawy jakości radioterapii

Tilted algebras and short chains of modules

We provide an affirmative answer for the question raised almost twenty years ago concerning the characterization of tilted artin algebras by the existence of a sincere finitely generated module which is not the middle of a short chain

Clinical significance of morphological variations of the inferior phrenic arteries

The rapid development of sciences such as genetics and molecular biology offers hope that better therapeutic methods can be developed and diagnosis and treatment made more effective. However, we must not forget that the basis for understanding the complex mechanisms of diseases and associated symptoms is knowledge of the relevant location and correlation among organs. In the present study, we focus on the clinical significance of the inferior phrenic artery. The diaphragm is a muscular structure that separatesthe abdominal and chest cavities. Thanks to this position, the inferior phrenic artery is much more significant than formerly assumed. A rich network of collaterals makes this vessel important in the development of neoplasms and metastases. Knowledge of anatomical variants of the inferior phrenic artery is also crucial for radiological procedures such as embolization. The main aim of this study is to review the involvement of the inferior phrenic artery in physiological and pathophysiological processes. This work has value for all practicing doctors, especially radiologists and surgeons

Extent, Awareness and Perception of Dissemination Bias in Qualitative Research: An Explorative Survey

BACKGROUND: Qualitative research findings are increasingly used to inform decision-making. Research has indicated that not all quantitative research on the effects of interventions is disseminated or published. The extent to which qualitative researchers also systematically underreport or fail to publish certain types of research findings, and the impact this may have, has received little attention. METHODS: A survey was delivered online to gather data regarding non-dissemination and dissemination bias in qualitative research. We invited relevant stakeholders through our professional networks, authors of qualitative research identified through a systematic literature search, and further via snowball sampling. RESULTS: 1032 people took part in the survey of whom 859 participants identified as researchers, 133 as editors and 682 as peer reviewers. 68.1% of the researchers said that they had conducted at least one qualitative study that they had not published in a peer-reviewed journal. The main reasons for non-dissemination were that a publication was still intended (35.7%), resource constraints (35.4%), and that the authors gave up after the paper was rejected by one or more journals (32.5%). A majority of the editors and peer reviewers "(strongly) agreed" that the main reasons for rejecting a manuscript of a qualitative study were inadequate study quality (59.5%; 68.5%) and inadequate reporting quality (59.1%; 57.5%). Of 800 respondents, 83.1% "(strongly) agreed" that non-dissemination and possible resulting dissemination bias might undermine the willingness of funders to support qualitative research. 72.6% and 71.2%, respectively, "(strongly) agreed" that non-dissemination might lead to inappropriate health policy and health care. CONCLUSIONS: The proportion of non-dissemination in qualitative research is substantial. Researchers, editors and peer reviewers play an important role in this. Non-dissemination and resulting dissemination bias may impact on health care research, practice and policy. More detailed investigations on patterns and causes of the non-dissemination of qualitative research are needed

Economic analysis and food security contribution of supplemental irrigation and farm ponds: evidence from northern Burkina Faso

Background: Dry spells are serious obstacles to rainfed agriculture in Sahelian countries. Various water harvesting techniques are used by farmers to reduce the impact of climate variability, but are not sufficient in the case of a prolonged drought lasting 2–3 weeks. The farmers believe supplemental irrigation is a good way to adapt rainfed agriculture to dry spells. In this study, we evaluated the food contribution and profitability of supplemental irrigation of rainfed crops comparing various farm ponds that collect runoff water from the surrounding landscape. Methods: We analyzed the contribution of supplemental irrigation to food security and compared the profitability of different types of ponds constructed by farmers in northern Burkina Faso. Human cereal requirement was used as indicators to analyze the contribution of supplemental irrigation to food security. The criteria for analyzing the profitability of the selected ponds were gross margin (GM), net present value (NPV), internal rate of return (IRR) and payback period (PBP). Results: Our results show that the additional yield of corn obtained with supplemental irrigation makes it possible to meet the monthly cereal needs of at least 17 people and generates an additional GM of FCFA 178,483 (US$ 309.26) compared to no irrigation. The estimate of the NPV, from IRR and PBP showed that the profitability of supplemental irrigation in 15 agricultural seasons varies between the type of ponds constructed. Conclusions: Given the up-front cost and the farmers’ lack of resources, the ponds require a subsidy or a credit policy to facilitate the adoption of supplemental irrigation in Sahelian countries. However, the irrigation strategies to optimize agricultural income remain a field of research to be explored

Current status of MELCOR 2.2 for fusion safety analyses

MELCOR is an integral code developed by Sandia National Laboratories (SNL) for the US Nuclear Regulatory Commission (USNRC) to perform severe accident analyses of Light Water Reactors (LWR). More recently, MELCOR capabilities are being extended also to analyze non-LWR fission technologies. Within the European MELCOR User Group (EMUG), organized in the framework of USNRC Cooperative Severe Accident Research Program (CSARP), an activity on the evaluation of the applicability of MELCOR 2.2 for fusion safety analyses has been launched and it has been coordinated by ENEA. The aim of the activity was to identify the physical models to be possibly implemented in MELCOR 2.2 necessary for fusion safety analyses, and to check if those models are already available in MELCOR 1.8.6 for fusion version, developed by Idaho National Laboratory (INL). From this activity, a list of modeling needs emerged from the safety analyses of fusion-related installations have been identified and described. Then, the importance of the various needs, intended as the priority for model implementation in the MELCOR 2.2 code, has been evaluated according to the technical expert judgement of the authors. In the present paper, the identified modeling needs are discussed. The ultimate goal would be to propose to have a single integrated MELCOR 2.2 code release capable to cover both fission and fusion applications