2,868 research outputs found
Bordering power Europe? The mobility-bordering nexus in and by the European Union
The EU has been built on the idea that enhanced transnational relations and free movement of persons between Member States have a positive impact on international cooperation and security. However, what we have witnessed in the past decade is a growing pressure to limit mobility, reinvigorated by the Covid-19 pandemic. Calls for a strengthened Schengen area go together with the externalization of European borders and the involvement of third states, but also with the reintroduction of border functions between Member States. Inside the EU free movement has been reduced if not stopped for fear of terrorism, irregular migration or the spread of viruses. Meanwhile, new techniques to govern mobility have emerged, affecting the role and meaning of borders. This article focuses on three dynamics of this process that entail a transformation of sovereignty, territoriality and rights: the externalization of borders, internal rebordering and logistification. The article argues that by focusing on what borders do rather than discussing what borders are, we can observe a more comprehensive transformation of borders within, around and outside the EU, a transformation that goes beyond the Westphalian imaginary and the simplistic alternative between hard and soft borders
A new formulation of oral viscous budesonide in treating of paediatric eosinophilic oesophagitis: a pilot study
OBJECTIVES:
Oral viscous budesonide is a recent therapeutic option for eosinophilic oesophagitis (EoE) compared with dietary restriction and inhaled steroids. This single-centre, open-label, not blinded study aims to evaluate the efficacy and safety of a new, preprepared oral viscous budesonide suspension (PVB) in children and adolescents with EoE.
METHODS:
We treated 36 children with PVB (29 boys; median age 12 years) with EoE diagnosed according to European Society for Paediatric Gastroenterology Hepatology and Nutrition guidelines. Patients <150 and >150 cm height received 2 and 4 mg PVB daily, respectively, for 12 weeks. Upper gastrointestinal endoscopy was performed at baseline, after 12 weeks of therapy and 24 weeks after the end of therapy. Baseline and post-treatment scores were calculated for symptoms, endoscopy, and histology. Serum cortisol was performed at baseline, 12, and 36 weeks.
RESULTS:
At the end of PVB trial, endoscopy showed macroscopic remission in 32 patients (88.9%), whereas at histology median pre- and post-treatment peak eosinophil count/high power field (HPF) markedly decreased from 42.2 (range: 15-100) to 2.9 (range: 0-30); moreover, mean symptom and histology scores impressively improved compared with baseline (P < 0.01). At 24 weeks after the end of PVB therapy, endoscopy showed oesophageal relapse in 21 patients (58.3%), whereas 15 (41.7%) were still in remission. Seven children (19.4%) with positive multichannel intraluminal impedance-pH were treated also with proton pump inhibitors. No significant difference between pre-/post-treatment morning cortisol levels occurred.
CONCLUSIONS:
The new PVB suspension presented in the present study is effective and safe for treating children with proven EoE. Larger placebo-controlled clinical trials would provide more information about dosing, efficacy, and long-term safety of this formulation, specifically designed for the oesophagus
The European Migration System and Global Justice. A First Appraisal
Migration is at the heart of the current political debate in Europe. Moreover,
the migration crisis has disclosed a number of normative and ethical issues
connected to the current management of migration in the EU. This report provides
a preliminary insight into the EU’s policy on migration. It looks specifically
at the terms the EU chooses, the definitions it devises and the concepts and
understandings it endorses in its migration policies. In order to grasp the actual
working of an emerging EU Migration System of Governance (EUMSG), the
same terms, concepts and definitions are also examined with reference to a set
of national cases: Italy, France, Germany, United Kingdom, Hungary, Greece
and Norway
Theoretical Investigation of Optical Conductivity in Ba [Fe(1-x)Co(x)]2 As2
We report on theoretical calculations of the optical conductivity of Ba
[Fe(1-x)Co(x)]2 As2, as obtained from density functional theory within the full
potential LAPW method. A thorough comparison with experiment shows that we are
able to reproduce most of the observed experimental features, in particular a
magnetic peak located at about 0.2 eV which we ascribe to antiferromagnetic
ordered magnetic stripes. We also predict a large in-plane anisotropy of this
feature, which agrees very well with measurements on detwinned crystals. The
effect of Co doping as well as the dependence of plasma frequency on the
magnetic order is also investigated
Chow's theorem and universal holonomic quantum computation
A theorem from control theory relating the Lie algebra generated by vector
fields on a manifold to the controllability of the dynamical system is shown to
apply to Holonomic Quantum Computation. Conditions for deriving the holonomy
algebra are presented by taking covariant derivatives of the curvature
associated to a non-Abelian gauge connection. When applied to the Optical
Holonomic Computer, these conditions determine that the holonomy group of the
two-qubit interaction model contains . In particular, a
universal two-qubit logic gate is attainable for this model.Comment: 13 page
Anisotropic in-plane optical conductivity in detwinned Ba(Fe1-xCox)2As2
We study the anisotropic in-plane optical conductivity of detwinned
Ba(Fe1-xCox)2As2 single crystals for x=0, 2.5% and 4.5% in a broad energy range
(3 meV-5 eV) across their structural and magnetic transitions. For temperatures
below the Neel transition, the topology of the reconstructed Fermi surface,
combined with the distinct behavior of the scattering rates, determines the
anisotropy of the low frequency optical response. For the itinerant charge
carriers, we are able to disentangle the evolution of the Drude weights and
scattering rates and to observe their enhancement along the orthorhombic
antiferromagnetic a-axis with respect to the ferromagnetic b-axis. For
temperatures above Ts, uniaxial stress leads to a finite in-plane anisotropy.
The anisotropy of the optical conductivity, leading to a significant dichroism,
extends to high frequencies in the mid- and near-infrared regions. The
temperature dependence of the dichroism at all dopings scales with the
anisotropy ratio of the dc conductivity, suggesting the electronic nature of
the structural transition. Our findings bear testimony to a large nematic
susceptibility that couples very effectively to the uniaxial lattice strain. In
order to clarify the subtle interplay of magnetism and Fermi surface topology
we compare our results with theoretical calculations obtained from density
functional theory within the full-potential linear augmented plane-wave method.Comment: 17 pages, 9 figure
PIXE and ToF-SIMS analysis of streaker samplers filters
This paper presents methodological innovations introduced in the characterisation of urban aerosol collected in Italy in a recent campaign. Two complementary ion beam analysis (IBA) techniques were used to analyse Nuclepore filters used in continuous streaker samplers to collect airborne particles in four Italian towns. Na to Pb elemental concentrations were obtained by particle induced X-ray emission (PIXE), while time of flight secondary ion mass spectrometry (ToF-SIMS) produced, on the same samples, time trends for several elements and molecular fragments. In addition, light attenuation measurements were used as a tracer for black carbon. The data produced by these three techniques was merged into a unique data set to address the characterisation of particulate matter sources. Correlations between elemental concentration trends (PIXE) and relative trends for molecular fragments (ToF-SIMS) and black carbon (light attenuation) have been studied by cluster and principal component analysis
Long and short term changes in abundance and distribution of butterflies: hints from the Lazio database
The DB on the occurrence data of the butterflies (Papilionoidea) of Lazio, at 14th February 2022 consisted of 36244 records including 154 species istributed throughout a total of 6719 sites. The data set included geoeferenced and chrono-referenced data collected from the literature, specialist-validated occurrences from websites (Forum Natura Mediterraneo, iNaturalist, Ornitho), as well as an important amount of original observations included in the database of the Lazio Biodiversity Observatory. All observations were used to create distribution maps. In order to evaluate any change in observations over time for the various species, all records were divided into three different periods: before 1980
(4425 records), 1980-2000 (6498 records) and post 2000 (25321 records). A finer subdivision was then examined within the post-2000 period: 2001-2007 (11888 records), 2008-2014 (4977 records), 2014-2021 (8456 records). Further analyses were carried out to highlight differences in the distribution of species as a function of altitude and / or changes in land use that have occurred in the last decades. The results show that qualitatively the species present in the region before 1980 are all still present today,
however the abundance of related observations in several cases has changed considerably. Observations of an important portion of the species have significantly decreased in recent years. This trend is observed in the majority of mountain species and various habitat-specialist butterflies regardless of altitude. In some other species, often the most common or habitat-generalist butterflies, an increase was observed. The causes of
these trends can be identified in the human land use and climate change, without excluding, however, the differences in data recording over time that could favor the most common species
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