6,549 research outputs found
Kawasaki disease: the role of immune complexes revisited
Kawasaki disease (KD) is an inflammatory disease in children associated with vasculitis affecting predominantly the coronary arteries and is now the most common cause of acquired heart disease in children in developed countries. The etiology of KD is unknown but epidemiological studies implicate an infectious agent or toxin, which causes disease in genetically predisposed individuals. The presence of immune complexes (ICs) in the serum of children with KD was established in numerous studies during the 1970s and 80s. More recent genetic studies have identified variation in Fcγ receptors and genes controlling immunoglobulin production associated with KD. In this review we link the genetic findings and IC studies and suggest a key role for their interaction in pathophysiology of the disease
Distance measures to compare real and ideal quantum processes
With growing success in experimental implementations it is critical to
identify a "gold standard" for quantum information processing, a single measure
of distance that can be used to compare and contrast different experiments. We
enumerate a set of criteria such a distance measure must satisfy to be both
experimentally and theoretically meaningful. We then assess a wide range of
possible measures against these criteria, before making a recommendation as to
the best measures to use in characterizing quantum information processing.Comment: 15 pages; this version in line with published versio
Memory texts and memory work: Performances of memory in and with visual media
The online version of this article can be found at: http://mss.sagepub.com/content/early/2010/05/24/175069801037003
Fabrication of high quality plan-view TEM specimens using the focused ion beam
We describe a technique using a focused ion beam instrument to fabricate high quality plan-view specimens for transmission electron microscopy studies. The technique is simple, site-specific and is capable of fabricating multiple large, >100 μm2 electron transparent windows within epitaxially-grown thin films. A film of La0.67Sr0.33MnO3 is used to demonstrate the technique and its structural and functional properties are surveyed by high resolution imaging, electron spectroscopy, atomic force microscopy and Lorentz electron microscopy. The window is demonstrated to have good thickness uniformity and a low defect density that does not impair the film’s Curie temperature. The technique will enable the study of in–plane structural and functional properties of a variety of epitaxial thin film systems
A simple high-sensitivity technique for purity analysis of xenon gas
We report on the development and performance of a high-sensitivity
purity-analysis technique for gaseous xenon. The gas is sampled at macroscopic
pressure from the system of interest using a UHV leak valve. The xenon present
in the sample is removed with a liquid-nitrogen cold trap, and the remaining
impurities are observed with a standard vacuum mass-spectroscopy device. Using
calibrated samples of xenon gas spiked with known levels of impurities, we find
that the minimum detectable levels of N2, O2, and methane are 1 ppb, 160 ppt,
and 60 ppt respectively. This represents an improvement of about a factor of
10,000 compared to measurements performed without a coldtrap.Comment: 20 pages, 5 figure
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