Zur Bewährung ehemaliger Funktionäre der Pionierorganisation "Ernst Thälmann" im sozialistischen Jugendverband: Parlamentsstudie 1975 ; Zusatzbericht

Im Rahmen der Parlamentsstudie wurden ca. 7.400 junge Arbeitnehmer und ca. 2.500 Studenten schriftlich befragt. Dabei wurde auch die eventuelle frühere Tätigkeit als Funktionär in der Pionierorganisation thematisiert. Für diejenigen, die eine Funktion innehatten wurde weiterhin ihre heutige Aktivität in der FDJ untersucht. Es zeigt sich, daß diejenigen Jugendlichen, die bereits in der Pionierorganisation eine Funktion übernahmen, dem Jugendverband positiver gegenüberstehen als andere Jugendliche. Sie übernahmen auch häufiger wieder eine Funktion in der FDJ. "Offensichtlich zeigen sich hier Fortschritte in der Kontinuität der Kaderentwicklung im sozialistischen Jugendverband." Weiterhin wenden sich die ehemaligen Pionierfunktionäre weniger häufig den Rundfunk- und Fernsehsendungen des "Klassengegners" zu als die anderen Jugendlichen. (psz

The 3-GDDs of type g3u2g^3u^2

A 3-GDD of type ${g^3u^2}$ exists if and only if $g$ and $u$ have the same parity, $3$ divides $u$ and $u\leq 3g$.Such a 3-GDD of type ${g^3u^2}$ is equivalent to an edge decomposition of $K_{g,g,g,u,u}$ into triangles

Uniformly resolvable decompositions of Kv in 1-factors and 4-stars

If X is a connected graph, then an X-factor of a larger graph is a spanning subgraph in which all of its components are isomorphic to X. A uniformly resolvable {X, Y }-decomposition of the complete graph Kv is an edge decomposition of Kv into exactly r X-factors and s Y -factors. In this article we determine necessary and sufficient conditions for when the complete graph Kv has a uniformly resolvable decompositions into 1-factors and K1,4-factors

Ozone-depleting substances (ODSs) and related chemicals

The amended and adjusted Montreal Protocol continues to be successful at reducing emissions and atmospheric abundances of most controlled ozone-depleting substances (ODSs).Global Ozone Research and Monitoring Projec

Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20

Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently inhibit the replication of bunyaviruses. We used a flow cytometry-based method to screen the ability of ∼500 unique ISGs from humans and rhesus macaques to inhibit the replication of Bunyamwera orthobunyavirus (BUNV), the prototype of both the Peribunyaviridae family and Bunyavirales order. Candidates possessing antibunyaviral activity were further examined using a panel of divergent bunyaviruses. Interestingly, one candidate, ISG20, exhibited potent antibunyaviral activity against most viruses examined from the Peribunyaviridae, Hantaviridae and Nairoviridae families, whereas phleboviruses (Phenuiviridae) largely escaped inhibition. Similar to other viruses known to be targeted by ISG20, the antibunyaviral activity of ISG20 is dependent upon its functional ribonuclease activity. Through use of an infectious VLP assay (based on the BUNV minigenome system), we confirmed that gene expression from all 3 viral segments is strongly inhibited by ISG20. Using in vitro evolution, we generated a substantially ISG20-resistant BUNV and mapped the determinants of ISG20 sensitivity/resistance. Taken together, we report that ISG20 is a broad and potent antibunyaviral factor yet some bunyaviruses are remarkably ISG20 resistant. Thus, ISG20 sensitivity/resistance could influence the pathogenesis of bunyaviruses, many of which are emerging viruses of clinical or veterinary significance