506 research outputs found

    The Implications of Insurance Status on Presentation, Surgical Management and Mortality among Non-Metastatic Breast Cancer Patients in Indiana

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    Background The National Breast and Cervical Cancer Early Detection Program seeks to reduce health care disparities by providing uninsured and underinsured women access to screening mammograms. The objective of this study is to identify the differences in presentation, surgical management, and mortality among nonmetastatic uninsured patients diagnosed through Indiana's Breast and Cervical Cancer Program compared with patients with private and government (Medicare or Medicaid) insurance. Methods Study data were obtained using the Indiana state cancer registry and Indiana's Breast and Cervical Cancer Program. Women aged 50 to 64 with an index diagnosis of stage 0 to III breast cancer from January 1, 2006 to December 31, 2013, were included in the study. Bivariate intergroup analysis was conducted. Kaplan-Meier estimates between insurance types were compared using the log rank test. All-cause mortality was evaluated using a mixed effects model. Results The groups differed significantly for sociodemographic and clinical variables. Uninsured Indiana Breast and Cervical Cancer Program patients presented with later disease stage (P < .001) and had the highest overall mortality (hazard ratio 2.2, P = .003). Surgical management only differed among stage III patients (P = .012). Conclusion To improve insurance-based disparities in Indiana, implementation of the Breast and Cervical Cancer Program in conjunction with expansion of insurance coverage to vulnerable low-income populations need to be optimized

    Genotype by environment interaction and stability of extra-early maize hybrids (Zea Mays L.) for yield evaluated under irrigation.

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    Maize (Zea mays L.) is the most important cereal crop produced in Ghana. However the change in environmental conditions, the expansion of maize to new agro-ecologies coupled with inadequate maize varieties available for the different environments affects yield improvement programmes in Ghana. Hence, the study is to investigate the influence of genotype by environment interaction on the maize hybrids and to identify stable and high yielding hybrids with superior agronomic for famers use in the country. The objectives of the study was to investigate the influence of genotype by environment interaction on the maize hybrids and to identify stable and high yielding hybrids with superior agronomic performance for famers use in Ghana. Thus, fifteen extra-early maize hybrids and three locally released checks were evaluated in a randomized complete block design with three replications in two locations in Ghana. The experiment was carried out at KNUST and Akomadan which represent the forest and forest transition zones of Ghana. Nine of the hybrids out of the fifteen hybrids evaluated produce above the average yield and the effect of genotype, location and genotype by location interaction was significant for grain yield. The GGE biplot used in this study revealed that TZEEI-1 x TZEEI-21, TZEEI-6 x TZEEI-21, TZEEI-15 x TZEEI-1 and TZEEI-29 x TZEEI-21 were high yielding and stable hybrids because they were closer to the ideal. The GGE biplot also identified Akomadan as the most ideal testing environment for these hybrids under irrigation

    Agronomic potential of “Dodzi”, an extra early-maturing maize cultivar

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    Production of short-cycle crop varieties reduces the risk of crop loss due to terminal droughts and ensures early harvest to fill the hunger gap. Two experiments were used to determine the yield potentials of elite extra-early (75- 80 days) maturing maize (Zea mays L.) varieties to recommend the best extra-early variety for commercial productionand use in Ghana. In the first experiment, two extra-early and eight early (90-95 days) maize varieties were evaluated in replicated field trials at 10 research stations in 1995 and 1996. In the second experiment, thetwo extra-early varieties, one recommended early variety, and the farmers’ check variety were evaluated at 38 and 28 farm sites in 1995 and 1996, respectively. Mean grain yields across the 10 on-station sites in 2 years were 3.5, 4.1, 4.6, and 3.4 t ha-1 for NAES EE W-SR (extraearly), NAES Pool 16 DT (extra-early), Dorke SR (early), and the farmers’ check variety, respectively. Mean yields of the four varieties across 66 farm sites in both years were 3.2, 3.4, 3.4, and 3.6 t ha-1, respectively. NAES EE W-SR was the earliest of all the varieties tested and the farmers’ variety was latest. Food preference tests showed that NAES EE W-SR was comparable to the farmers’ check variety in suitability for local dish preparations. The National Variety Release Committee subsequently approved and released NAES EE W-SR under the local name “Dodzi”. “Dodzi” is recommended for early planting and harvesting throughout Ghana

    Broadband Dielectric Spectroscopic Detection of Ethanol: A Side-by-Side Comparison of ZnO and HKUST-1 MOFs as Sensing Media

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    The most common gas sensors are based on chemically induced changes in electrical resistivity and necessarily involve making imperfect electrical contacts to the sensing materials, which introduce errors into the measurements. We leverage thermal- and chemical-induced changes in microwave propagation characteristics (i.e., S-parameters) to compare ZnO and surface-anchored metal-organic-framework (HKUST-1 MOF) thin films as sensing materials for detecting ethanol vapor, a typical volatile organic compound (VOC), at low temperatures. We show that the microwave propagation technique can detect ethanol at relatively low temperatures (\u3c100 \u3e°C), and afford new mechanistic insights that are inaccessible with the traditional dc-resistance-based measurements. In addition, the metrological technique avoids the inimical measurand distortions due to parasitic electrical effects inherent in the conductometric volatile organic compound detection

    Broadband Dielectric Spectroscopic Detection of Ethanol: A Side-by-Side Comparison of ZnO and HKUST-1 MOFs as Sensing Media†,‡

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    The most common gas sensors are based on chemically induced changes in electrical resistivity and necessarily involve making imperfect electrical contacts to the sensing materials, which introduce errors into the measurements. We leverage thermal- and chemical-induced changes in microwave propagation characteristics (i.e., S-parameters) to compare ZnO and surface-anchored metal–organic-framework (HKUST-1 MOF) thin films as sensing materials for detecting ethanol vapor, a typical volatile organic compound (VOC), at low temperatures. We show that the microwave propagation technique can detect ethanol at relatively low temperatures (<100 °C), and afford new mechanistic insights that are inaccessible with the traditional dc-resistance-based measurements. In addition, the metrological technique avoids the inimical measurand distortions due to parasitic electrical effects inherent in the conductometric volatile organic compound detection

    Broadband Dielectric Spectroscopic Detection of Aliphatic Alcohol Vapors with Surface-Mounted HKUST-1 MOFs as Sensing Media †

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    We leveraged chemical-induced changes to microwave signal propagation characteristics (i.e., S-parameters) to characterize the detection of aliphatic alcohol (methanol, ethanol, and 2-propanol) vapors using TCNQ-doped HKUST-1 metal-organic-framework films as the sensing material, at temperatures under 100 ◩C. We show that the sensitivity of aliphatic alcohol detection depends on the oxidation potential of the analyte, and the impedance of the detection setup depends on the analyte-loading of the sensing medium. The microwaves-based detection technique can also afford new mechanistic insights into VOC detection, with surface-anchored metal-organic frameworks (SURMOFs), which is inaccessible with the traditional coulometric (i.e., resistance-based) measurements

    Broadband Dielectric Spectroscopic Detection of Aliphatic Alcohol Vapors With Surface-Mounted HKUST-1 MOFs as Sensing Media

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    We leveraged chemical-induced changes to microwave signal propagation characteristics (i.e., S-parameters) to characterize the detection of aliphatic alcohol (methanol, ethanol, and 2-propanol) vapors using TCNQ-doped HKUST-1 metal-organic-framework films as the sensing material, at temperatures under 100 °C. We show that the sensitivity of aliphatic alcohol detection depends on the oxidation potential of the analyte, and the impedance of the detection setup depends on the analyte-loading of the sensing medium. The microwaves-based detection technique can also afford new mechanistic insights into VOC detection, with surface-anchored metal-organic frameworks (SURMOFs), which is inaccessible with the traditional coulometric (i.e., resistance-based) measurements

    Agronomic potentials of quality protein maize hybrids developed in Ghana

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    A quality protein maize (QPM) hybrid programme was started in 1991 to develop and promote high and stableyielding QPM hybrids to increase production of nutritionally superior maize varieties in Ghana. Six 3- way QPM hybrids developed from inbred lines originating from germplasm of the International Centre for Maize and Wheat Improvement (CIMMYT) were evaluated on research stations and in farmers\' fields in Ghana from 1995 to 1996. In the on-station evaluations, grain yields across 10 sites in both years averaged 6.0 ton ha-1 for the three hybrids (GH132-28, GH110-5 and GH2328-88), 5.22 ton ha-1 for Obatanpa, and 3.60 ton ha-1 for the local maize variety. In farmers\' fields, data from over 50 farm sites in 1995 and 1996 showed mean yields of 4.95 ton ha-1 for the three hybrids, and 4.28 ton ha-1 for Obatanpa compared to 3.59 ton ha-1 for farmers\' varieties. On the average, the hybrids were similar to Obatanpa in days to 50 per cent silking, but were shorter in plant height and ear placement. Consumer preference tests showed that the three hybrids were rated similar to the local variety in popular traditional food preparations such as ‘kenkey\' and ‘tuo zafi\'. In 1997, the National Variety Release Committee approved the release of GH132-28, GH110-5, and GH2328-88 under the local names Dadaba, Mamaba, and CIDA-ba, respectively. These hybrids are recommended for planting in all the major agro-ecologies to boost maize production in Ghana.Les variĂ©tĂ©s de maĂŻs hybride (Zea mays L.) dont les plus sĂ©sirĂ©es que les variĂ©tĂ©s de pollinisation libre Ă  cause de leur uniformtĂ© et leurs potentiels de rendement plus Ă©levĂ©s. Pour augmenter la production de variĂ©tĂ©s de maĂŻs nutritionnellement supĂ©rieures au Ghana, I\'Institut de Recherche de Cultures a mis en place un programme hybrid de maĂŻs protĂ©ique de qualitĂ© (MPQ) en 1991 pour dĂ©velopper et promouvoir des hybrides de MPQ de rendement Ă©levĂ©s et stable. Six hybrids en trois de MPQ dĂ©veloppĂ©s d\'issu de la mĂȘme souch provenant de germeplasmes de CIMMYT (Centre International pour I\'amĂ©lioration de maĂŻs et de blĂ©) Ă©taient Ă©valuĂ©s aux stations de recherches et aux champs d\'agriculteurs au Ghana de 1995 Ă  1996. Dans les Ă©valuations sur place, les rendements de grain Ă  travers 10 sites dans les deux annĂ©es ont atteint la moyenne de 6.0 ton ha-1 pour les trois hybrids (GH132-28, GH110-5 et GH2328-88), 5.22 ton ha-1 pour \'Obatanpa\' et 3.60 ton ha-1 pour la variĂ©tĂ©s de maĂŻs local. Sur les champs d\'agriculteurs des donnĂ©es de plus que 50 sites de champs en 1995 et 1996 montraient les rendements moyens de 4.95 ton ha-1 pour les trois hybrids et 4.28 ton ha-1 pour les \'Obatanpa\' comparĂ©es Ă  3.59 ton ha-1 pour les variĂ©tĂ©s d\'agriculteurs. En moyenne, les hybrides Ă©taient semblables Ă  \'Obatanpa\' en jours jusqu Ă  50% d\'apparition de soie maĂŻs Ă©taient plus courtes en taille de plante et en placement d\'Ă©pi. Les essais de prĂ©fĂ©rence de consommateur montraient que les trios hybrides Ă©taient Ă©valuĂ©s semblables Ă  la variĂ©tĂ© locale dans les prĂ©parations de nouriture traditionnelle populaire telle que \'kenkey\' et \'tuo zafi\'. En 1997, le comitĂ© pour la mise en vente de VariĂ©tĂ© Nationale a approuvĂ© la mise en vente de GH132-28, GH110-5 et GH2328-88 sous les noms locaux respectifs de Dadaba, Mamaba, et CIDA-ba. Ce hybrides sont recommandĂ©s pour la popultion dans toutes les agroĂ©clogies majeures pour stimuler la production de maĂŻs au Ghana. Ghana Journal of Agricultural Science Vol. 40 (1) 2007: pp. 81-8

    Influence of operating parameters on the biodegradation of steroid estrogens and nonylphenolic compounds during biological wastewater treatment processes

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    This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Environmental Science & Technology, copyright © American Chemical Society after peer review. To access the final edited and published work see http://pubs.acs.org/doi/abs/10.1021/es901612v.This study investigated operational factors influencing the removal of steroid estrogens and nonylphenolic compounds in two sewage treatment works, one a nitrifying/denitrifying activated sludge plant and the other a nitrifying/denitrifying activated sludge plant with phosphorus removal. Removal efficiencies of >90% for steroid estrogens and for longer chain nonylphenol ethoxylates (NP4−12EO) were observed at both works, which had equal sludge ages of 13 days. However, the biological activity in terms of milligrams of estrogen removed per day per tonne of biomass was found to be 50−60% more efficient in the nitrifying/denitrifying activated sludge works compared to the works which additionally incorporated phosphorus removal. A temperature reduction of 6 °C had no impact on the removal of free estrogens, but removal of the conjugated estrone-3-sulfate was reduced by 20%. The apparent biomass sorption (LogKp) values were greater in the nitrifying/denitrifying works than those in the nitrifying/denitrifying works with phosphorus removal for both steroid estrogens and nonylphenolic compounds possibly indicating a different cell surface structure and therefore microbial population. The difference in biological activity (mg tonne−1 d−1) identified in this study, of up to seven times, suggests that there is the potential for enhancing the removal of estrogens and nonylphenols if more detailed knowledge of the factors responsible for these differences can be identified and maximized, thus potentially improving the quality of receiving waters.Public Utilities Board (Singapore), Anglian Water Ltd, Severn Trent Water Ltd, Thames Water Utilities Ltd, United Utilities 393 Plc and Yorkshire Water Services
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