Identified particle measurements at large transverse momenta from p+p to Au+Au collisions at RHIC

Measurements of various particle species over an extended momentum range provide a sensitive experimental tool for investigating particle production mechanisms in hadronic collisions. Comparison of the spectral shapes from different collision centralities measured with the STAR detector at RHIC allows one to study the interplay of soft and hard particle production for mesons and investigate various baryon-meson effects. Systematic studies of identified particle spectra for various colliding systems and different incident energies provide additional insights toward the interplay between fragmentation and non-fragmentation contributions to the particle production. In these proceedings we present a systematic study of transverse momentum spectra for charged pions, protons and antiprotons from Au+Au and Cu+Cu data at sqrt(s_NN)=200 and 62.4 GeV as a function of collision centrality. We compare those measurements with p+p and d+Au data, investigating the system effects on energy loss.Comment: 6 pages, 4 figures, proceedings for the Lake Louise Winter Institute 2007, 19th-24th February 2007, Alberta, Canad

Summary of Workshop to Review an OMB Report on Regulatory Risk Assessment and Management

Summary of the results of an invitational workshop conducted to peer review the 1990 OMB report, CURRENT REGULATORY ISSUES IN Risk ASSESSMENT AND Risk MANAGENMENTIN REGULATORY PROGRAM OF THE UNITED STATES GOVERNMENT, APRIL 1, 1990 - MARCH 31, 1991

System size dependence of freeze-out properties at RHIC

The STAR experiment at RHIC has measured identified pi(+/-), K(+/-) and p(pbar) spectra and ratios from sqrt(s_NN) = 62.4 and 200 GeV Cu+Cu collisions. The new Cu+Cu results are studied with hydro-motivated blast-wave and statistical model frameworks in order to characterize the freeze-out properties of this system. Along with measurements from Au+Au and p+p collisions, the obtained freeze-out parameters are discussed as a function of collision energy, system size, centrality and inferred energy density. This multi-dimensional systematic study reveals the importance of the collision geometry and furthers our understanding of the QCD phases.Comment: 6 pages, 6 figures, poster proceedings for the Quark Matter 2006 Conference, Shanghai, China, 14th-20th Novermber 2006, submitted to the International Journal of Modern Physics

Insights into activity-dependent map formation from the retinotectal system: a middle-of-the-brain perspective

ABSTRACT: The development of orderly topographic maps in the central nervous system (CNS) results from a collaboration of chemoaffinity cues that establish the coarse organization of the projection and activity-dependent mechanisms that fine-tune the map. Using the retinotectal projection as a model system, we describe evidence that biochemical tags and patterned neural activity work in parallel to produce topographically ordered axonal projections. Finally, we review recent experiments in other CNS projections that support the proposition that cooperation between molecular guidance cues and activity-dependent processes constitutes a general paradigm for CNS map formation

Short-term exposure to heat stress attenuates appetite and intestinal integrity in growing pigs 1

Acute heat stress (HS) and heat stroke can be detrimental to the health, well-being, and performance of mammals such as swine. Therefore, our objective was to chronologically characterize how a growing pig perceives and initially copes with a severe heat load. Crossbred gilts (n=32; 63.8±2.9 kg) were subjected to HS conditions (37°C and 40% humidity) with ad libitum intake for 0, 2, 4, or 6 h (n=8/time point). Rectal temperature (Tr), respiration rates (RR), and feed intake were determined every 2 h. Pigs were euthanized at each time point and fresh ileum and colon samples were mounted into modified Ussing chambers to assess ex vivo intestinal integrity and function. Transepithelial electrical resistance (TER) and fluorescein isothiocyanate-labeled dextran (FD4) permeability were assessed. As expected, Tr increased linearly over time (P\u3c0.001) with the highest temperature observed at 6 h of HS. Compared to the 0-h thermal-neutral (TN) pigs, RR increased (230%; P\u3c0.001) in the first 2 h and remained elevated over the 6 h of HS (P\u3c0.05). Feed intake was dramatically reduced due to HS and this corresponded with significant changes in plasma glucose, ghrelin, and glucose-dependent insulinotropic peptide (P\u3c0.050). At as early as 2 h of HS, ileum TER linearly decreased (P\u3c0.01), while FD4 linearly increased with time (P\u3c0.05). Colon TER and FD4 changed due to HS in quadratic responses over time (P=0.050) similar to the ileum but were less pronounced. In response to HS, ileum and colon heat shock protein (HSP) 70 mRNA and protein abundance increased linearly over time (P\u3c0.050). Altogether, these data indicated that a short duration of HS (2-6 h) compromised feed intake and intestinal integrity in growing pigs

Dietary sulfur concentration has no effect on In Vitro fermentative activity of ruminal mixed microorganisms

Beef Cattle Research, 2011 is known as Cattlemen’s Day, 2011We previously reported that elevated concentrations of dietary sulfur (0.65% sulfur, dry basis) in finishing diets containing dried distillers grains with solubles decreased dry matter intake and average daily gains of feedlot cattle. Furthermore, high dietary sulfur concentrations yielded lower ruminal concentrations of volatile fatty acids, but were associated with increased ruminal ammonia concentrations and improved total tract digestibility of the diet. The objective of this study was to investigate, in culture tubes, effects of added sulfur on in vitro dry matter disappearance, volatile fatty acid profiles, and ammonia concentrations from substrates containing different sulfur concentrations when fermented by mixed ruminal microorganisms from a steer fed a diet based on corn and alfalfa

Correlations for Boundary-Layer Transition on Mars Science Laboratory Entry Vehicle Due to Heat-Shield Cavities

The influence of cavities (for attachment bolts) on the heat-shield of the proposed Mars Science Laboratory entry vehicle has been investigated experimentally and computationally in order to develop a criterion for assessing whether the boundary layer becomes turbulent downstream of the cavity. Wind tunnel tests were conducted on the 70-deg sphere-cone vehicle geometry with various cavity sizes and locations in order to assess their influence on convective heating and boundary layer transition. Heat-transfer coefficients and boundary-layer states (laminar, transitional, or turbulent) were determined using global phosphor thermography

Lentiviral vectors with amplified beta cell-specific gene expression.

An important goal of gene therapy is to be able to deliver genes, so that they express in a pattern that recapitulates the expression of an endogenous cellular gene. Although tissue-specific promoters confer selectivity, in a vector-based system, their activity may be too weak to mediate detectable levels in gene-expression studies. We have used a two-step transcriptional amplification system to amplify gene expression from lentiviral vectors using the human insulin promoter. In this system, the human insulin promoter drives expression of a potent synthetic transcription activator (the yeast GAL4 DNA-binding domain fused to the activation domain of the Herpes simplex virus-1 VP16 activator), which in turn activates a GAL4-responsive promoter, driving the enhanced green fluorescent protein reporter gene. Vectors carrying the human insulin promoter did not express in non-beta-cell lines, but expressed in murine insulinoma cell lines, indicating that the human insulin promoter was capable of conferring cell specificity of expression. The insulin-amplifiable vector was able to amplify gene expression five to nine times over a standard insulin-promoter vector. In primary human islets, gene expression from the insulin-promoted vectors was coincident with insulin staining. These vectors will be useful in gene-expression studies that require a detectable signal and tissue specificity

Detection of Voigt Spectral Line Profiles of Hydrogen Radio Recombination Lines toward Sagittarius B2(N)

We report the detection of Voigt spectral line profiles of radio recombination lines (RRLs) toward Sagittarius B2(N) with the 100-m Green Bank Telescope (GBT). At radio wavelengths, astronomical spectra are highly populated with RRLs, which serve as ideal probes of the physical conditions in molecular cloud complexes. An analysis of the Hn(alpha) lines presented herein shows that RRLs of higher principal quantum number (n>90) are generally divergent from their expected Gaussian profiles and, moreover, are well described by their respective Voigt profiles. This is in agreement with the theory that spectral lines experience pressure broadening as a result of electron collisions at lower radio frequencies. Given the inherent technical difficulties regarding the detection and profiling of true RRL wing spans and shapes, it is crucial that the observing instrumentation produce flat baselines as well as high sensitivity, high resolution data. The GBT has demonstrated its capabilities regarding all of these aspects, and we believe that future observations of RRL emission via the GBT will be crucial towards advancing our knowledge of the larger-scale extended structures of ionized gas in the interstellar medium (ISM)