Research Needs and Learning Format Preferences of Graduate Students at a Large Public University: An Exploratory Study

This article reports on a study of research needs and learning preferences of graduate students at a public research university. A sequential exploratory mixed-method design was used, with a survey instrument developed from an initial qualitative stage. Significant differences were found between master’s and doctoral students’ and on-campus and online students’ confidence with several research skills. Graduate students overall prefer asynchronous online options and in-person workshops over synchronous online instruction and in-class presentations for learning research skills. The article concludes with a discussion of the value of the sequential exploratory mixed-method design for informing practice at an individual institution.Publisher allows immediate open acces

Experimental measurement of efficiency and transport coherence of a cold atom Brownian motor in optical lattices

The rectification of noise into directed movement or useful energy is utilized by many different systems. The peculiar nature of the energy source and conceptual differences between such Brownian motor systems makes a characterization of the performance far from straightforward. In this work, where the Brownian motor consists of atoms interacting with dissipative optical lattices, we adopt existing theory and present experimental measurements for both the efficiency and the transport coherence. We achieve up to 0.3% for the efficiency and 0.01 for the P\'eclet number

Pyometra in Bitches Induces Elevated Plasma Endotoxin and Prostaglandin F(2α )Metabolite Levels

Endotoxemia in bitches with pyometra can cause severe systemic effects directly or via the release of inflammatory mediators. Plasma endotoxin concentrations were measured in ten bitches suffering from pyometra with moderately to severely deteriorated general condition, and in nine bitches admitted to surgery for non-infectious reasons. Endotoxin samples were taken on five occasions before, during and after surgery. In addition, urine and uterine bacteriology was performed and hematological, blood biochemical parameters, prostaglandin F(2α )metabolite 15-ketodihydro-PGF(2α )(PG-metabolite), progesterone and oestradiol (E(2)-17β) levels were analysed. The results confirm significantly increased plasma levels of endotoxin in bitches with pyometra and support previous reports of endotoxin involvement in the pathogenesis of the disease. Plasma concentrations of PG-metabolite were elevated in pyometra bitches and provide a good indicator of endotoxin release since the concentrations were significantly correlated to the endotoxin levels and many other hematological and chemistry parameters. The γ-globulin serum protein electrophoresis fraction and analysis of PG-metabolite can be valuable in the diagnosis of endotoxin involvement if a reliable, rapid and cost-effective test for PG-metabolite analysis becomes readily available in the future. Treatment inhibiting prostaglandin biosynthesis and related compounds could be beneficial for bitches suffering from pyometra

Assessment of decorin-binding protein A to the infectivity of Borrelia burgdorferi in the murine models of needle and tick infection

<p>Abstract</p> <p>Background</p> <p>Decorin-binding proteins (Dbps) A and B of <it>Borrelia burgdorferi</it>, the agent of Lyme disease, are surface-exposed lipoproteins that presumably bind to the extracellular matrix proteoglycan, decorin. <it>B. burgdorferi </it>infects various tissues including the bladder, heart, joints, skin and the central nervous system, and the ability of <it>B. burgdorferi </it>to bind decorin has been hypothesized to be important for this disseminatory pathogenic strategy.</p> <p>Results</p> <p>To determine the role of DbpBA in the infectious lifecycle of <it>B. burgdorferi</it>, we created a DbpBA-deficient mutant of <it>B. burgdorferi </it>strain 297 and compared the infectious phenotype of the mutant to the wild-type strain in the experimental murine model of Lyme borreliosis. The mutant strain exhibited a 4-log decrease in infectivity, relative to the wild-type strain, when needle inoculated into mice. Upon complementation of the DbpBA-mutant strain with DbpA, the wild-type level of infectivity was restored. In addition, we demonstrated that the DbpBA-deficient mutant was able to colonize <it>Ixodes scapularis </it>larval ticks after feeding on infected mice and persist within the ticks during the molt to the nymphal state. Moreover, surprisingly, the DbpBA-mutant strain was capable of being transmitted to naïve mice via tick bite, giving rise to infected mice.</p> <p>Conclusion</p> <p>These results suggest that DbpBA is not required for the natural tick-transmission process to mammals, despite inferences from needle-inoculation experiments implying a requirement for DbpBA during mammalian infection. The combined findings also send a cautionary note regarding how results from needle-inoculation experiments with mice should be interpreted.</p

PERFORMANCE DETERMINING FACTORS IN ELITE SPRINTERS DURING SPRINT START AND TWO FOLLOWING SUCCESSIVE SUPPORTS

Sprint start out of the blocks and successive acceleration are technically challenging as the athlete goes from a bended to a forward leaning position. Therefore, the body center of mass (COM) has to be accelerated forward and upwards. Optimal sprinting performance relies on attaining maximal forward acceleration. However, adequate vertical acceleration must be generated to reach sufficient height to prepare for the following step (Weyand, 2000). Horizontal acceleration is mainly determined by the horizontal ground reaction force that will affect sprint velocity and therefore final sprint performance (Mero, 1988). Kinematics and kinetics of the start action and maximal sprinting were intensively studied; however little is known on the transition from the set position to the running position during the first two strides. This study aims to identify the factors in the start action as well as in the first and second contact after block clearance that determine sprinting performance in terms of speed and acceleration

Influence of the lattice topography on a three-dimensional, controllable Brownian motor

We study the influence of the lattice topography and the coupling between motion in different directions, for a three-dimensional Brownian motor based on cold atoms in a double optical lattice. Due to controllable relative spatial phases between the lattices, our Brownian motor can induce drifts in arbitrary directions. Since the lattices couple the different directions, the relation between the phase shifts and the directionality of the induced drift is non trivial. Here is therefore this relation investigated experimentally by systematically varying the relative spatial phase in two dimensions, while monitoring the vertically induced drift and the temperature. A relative spatial phase range of 2pi x 2pi is covered. We show that a drift, controllable both in speed and direction, can be achieved, by varying the phase both parallel and perpendicular to the direction of the measured induced drift. The experimental results are qualitatively reproduced by numerical simulations of a simplified, classical model of the system

Characterisation of a three-dimensional Brownian motor in optical lattices

We present here a detailed study of the behaviour of a three dimensional Brownian motor based on cold atoms in a double optical lattice [P. Sjolund et al., Phys. Rev. Lett. 96, 190602 (2006)]. This includes both experiments and numerical simulations of a Brownian particle. The potentials used are spatially and temporally symmetric, but combined spatiotemporal symmetry is broken by phase shifts and asymmetric transfer rates between potentials. The diffusion of atoms in the optical lattices is rectified and controlled both in direction and speed along three dimensions. We explore a large range of experimental parameters, where irradiances and detunings of the optical lattice lights are varied within the dissipative regime. Induced drift velocities in the order of one atomic recoil velocity have been achieved.Comment: 8 pages, 14 figure

The effect of paternalistic alternatives on attitudes toward default nudges

Nudges are increasingly being proposed and used as a policy tool around the world. The success of nudges depends on public acceptance. However, several questions about what makes a nudge acceptable remain unanswered. In this paper, we examine whether policy alternatives to nudges influence the public's acceptance of these nudges: Do attitudes change when the nudge is presented alongside either a more paternalistic policy alternative (legislation) or a less paternalistic alternative (no behavioral intervention)? In two separate samples drawn from the Swedish general public, we find a very small effect of alternatives on the acceptability of various default nudges overall. Surprisingly, we find that when the alternative to the nudge is legislation, acceptance decreases and perceived intrusiveness increases (relative to conditions where the alternative is no regulation). An implication of this finding is that acceptance of nudges may not always automatically increase when nudges are explicitly compared to more paternalistic alternatives

Particle Dark Matter Physics: An Update

This write--up gives a rather elementary introduction into particle physics aspects of the cosmological Dark Matter puzzle. A fairly comprehensive list of possible candidates is given; in each case the production mechanism and possible ways to detect them (if any) are described. I then describe detection of the in my view most promising candidates, weakly interacting massive particles or WIMPs, in slightly more detail. The main emphasis will be on recent developments.Comment: Invited talk at the 5th Workshop on Particle Physics Phenomenology, Pune, India, January 1998; 21 pages, LaTeX with equation.st