25 research outputs found
ONYX-015: mechanisms of action and clinical potential of a replication-selective adenovirus
Get PDFAccumulated knowledge in the molecular processes of tumour development combined with the availability of genetically modified viruses resemble the basis for new promising cancer therapeutics. The main advantages of employing replication-competent viruses are achievement of tumour selective killing and amplification of their oncolytic potential within the tumour mass. In this review, we describe the development of ONYX-015, one of the first and most advanced replication-competent viruses for cancer therapy. We discuss the molecular biology of this therapeutic approach and the interesting results obtained with this virus in clinical trials
Psychometric properties of the eating disorder examination-questionnaire in Japanese adolescents
Full text linkThe Importance of Responsivity Factors in Predicting Reductions in Antisocial Attitudes and Cognitive Distortions Among Adult Male Offenders
No full textHeavy drinking occasions in relation to ischaemic heart disease mortality-- An 11-22 year follow-up of the 1984 and 1995 US National Alcohol Surveys
No full textPsychological Functioning and Substance Abuse Before andAfter the 1992 LosAngeles Riot in a Community Sample ofWODlent
No full textPhysical Activity in Gastric Bypass Patients: Associations with Weight Loss and Psychosocial Functioning at 12-Month Follow-Up
No full textThe Effects of a Problem Solving-Based Intervention on Depressive Symptoms and HIV Medication Adherence Are Independent
No full textDepressive symptoms are a risk factor for all-cause mortality: results from a prospective population-based study among 3,080 cancer survivors from the PROFILES registry
No full textPsychometric Evaluation of the Eating Disorder Examination-Questionnaire for Bariatric Surgery Candidates
No full text
