Effects of Daily News Sentiment on Stock Price Forecasting

Predicting future prices of a stock is an arduous task to perform. However, incorporating additional elements can significantly improve our predictions, rather than relying solely on a stock's historical price data to forecast its future price. Studies have demonstrated that investor sentiment, which is impacted by daily news about the company, can have a significant impact on stock price swings. There are numerous sources from which we can get this information, but they are cluttered with a lot of noise, making it difficult to accurately extract the sentiments from them. Hence the focus of our research is to design an efficient system to capture the sentiments from the news about the NITY50 stocks and investigate how much the financial news sentiment of these stocks are affecting their prices over a period of time. This paper presents a robust data collection and preprocessing framework to create a news database for a timeline of around 3.7 years, consisting of almost half a million news articles. We also capture the stock price information for this timeline and create multiple time series data, that include the sentiment scores from various sections of the article, calculated using different sentiment libraries. Based on this, we fit several LSTM models to forecast the stock prices, with and without using the sentiment scores as features and compare their performances.Comment: 9th ICBAI conference on December'2022 at IIM Bangalor

Periodontitis and Systemic Diseases: A Review

Periodontitis is one of the inflammatory-infectious diseases of the oral cavity, which results in an alteration in the production of host inflammatory mediators. Oral cavity has plentiful diverse bacteria that can spread different sites of the body particularly in immune compromised individuals and results in various systemic diseases. As the oral cavity is the mirror image of our systemic health, hence maintenance of oral health is equally important. This paper reviews the etiology of periodontitis and systemic relation

Steps towards understanding variation for water and nitrogen uptake and use in Brassica napus

Non-Peer Reviewe

Site amplification in the Kathmandu Valley during the 2015 M7.6 Gorkha, Nepal earthquake

The 25th April 2015 M7.6 Gorkha earthquake caused significant damage to buildings and infrastructure in both Kathmandu and surrounding areas as well as triggering numerous, large landslides. This resulted in the loss of approximately 8600 lives. In order to learn how the impact of such events can be reduced on communities both in Nepal and elsewhere, the Earthquake Engineering Field Investigation Team (EEFIT) reconnaissance mission was undertaken, aiming to look at damage patterns within the country. Passive, microtremor recordings in severely damaged areas of the Kathmandu Valley, as well as at the main seismic recording station in Kathmandu (USGS station KATNP) are used to determined preliminary shear wave velocity (Vs) profiles for each site. These profiles are converted into spectral acceleration using the input motion of the Gorkha earthquake. The results are limited, but show clear site amplification within the Siddhitol Region. The resulting ground motions exceed the design levels from the Nepalese Building Codes, indicating the need for site-specific hazard analysis and for revision of the building code to address the effect of site amplificatio

The homeobox gene BREVIPEDICELLUS is a key regulator of inflorescence architecture in Arabidopsis

Flowering plants display a remarkable range of inflorescence architecture, and pedicel characteristics are one of the key contributors to this diversity. However, very little is known about the genes or the pathways that regulate pedicel development. The brevipedicellus (bp) mutant of Arabidopsis thaliana displays a unique phenotype with defects in pedicel development causing downward-pointing flowers and a compact inflorescence architecture. Cloning and molecular analysis of two independent mutant alleles revealed that BP encodes the homeodomain protein KNAT1, a member of the KNOX family. bp-1 is a null allele with deletion of the entire locus, whereas bp-2 has a point mutation that is predicted to result in a truncated protein. In both bp alleles, the pedicels and internodes were compact because of fewer cell divisions; in addition, defects in epidermal and cortical cell differentiation and elongation were found in the affected regions. The downward-pointing pedicels were produced by an asymmetric effect of the bp mutation on the abaxial vs. adaxial sides. Cell differentiation, elongation, and growth were affected more severely on the abaxial than adaxial side, causing the change in the pedicel growth angle. In addition, bp plants displayed defects in cell differentiation and radial growth of the style. Our results show that BP plays a key regulatory role in defining important aspects of the growth and cell differentiation of the inflorescence stem, pedicel, and style in Arabidopsis

Target of Rapamycin Signaling Regulates Metabolism, Growth, and Life Span in Arabidopsis

Target of Rapamycin (TOR) is a major nutrition and energy sensor that regulates growth and life span in yeast and animals. In plants, growth and life span are intertwined not only with nutrient acquisition from the soil and nutrition generation via photosynthesis but also with their unique modes of development and differentiation. How TOR functions in these processes has not yet been determined. To gain further insights, rapamycin-sensitive transgenic Arabidopsis thaliana lines (BP12) expressing yeast FK506 Binding Protein12 were developed. Inhibition of TOR in BP12 plants by rapamycin resulted in slower overall root, leaf, and shoot growth and development leading to poor nutrient uptake and light energy utilization. Experimental limitation of nutrient availability and light energy supply in wild-type Arabidopsis produced phenotypes observed with TOR knockdown plants, indicating a link between TOR signaling and nutrition/light energy status. Genetic and physiological studies together with RNA sequencing and metabolite analysis of TOR-suppressed lines revealed that TOR regulates development and life span in Arabidopsis by restructuring cell growth, carbon and nitrogen metabolism, gene expression, and rRNA and protein synthesis. Gain- and loss-of-function Ribosomal Protein S6 (RPS6) mutants additionally show that TOR function involves RPS6-mediated nutrition and light-dependent growth and life span in Arabidopsis

Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis.

Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and numerous internal organs and a severe fibroproliferative vasculopathy resulting frequently in severe disability and high mortality. Although the etiology of SSc is unknown and the detailed mechanisms responsible for the fibrotic process have not been fully elucidated, one important observation from a large US population study was the demonstration of a late onset of SSc with a peak incidence between 45 and 54 years of age in African-American females and between 65 and 74 years of age in white females. Although it is not appropriate to consider SSc as a disease of aging, the possibility that senescence changes in the cellular elements involved in its pathogenesis may play a role has not been thoroughly examined. The process of cellular senescence is extremely complex, and the mechanisms, molecular events, and signaling pathways involved have not been fully elucidated; however, there is strong evidence to support the concept that oxidative stress caused by the excessive generation of reactive oxygen species may be one important mechanism involved. On the other hand, numerous studies have implicated oxidative stress in SSc pathogenesis, thus, suggesting a plausible mechanism in which excessive oxidative stress induces cellular senescence and that the molecular events associated with this complex process play an important role in the fibrotic and fibroproliferative vasculopathy characteristic of SSc. Here, recent studies examining the role of cellular senescence and of oxidative stress in SSc pathogenesis will be reviewed

Characterization and application of a sterol esterase immobilized on polyacrylate epoxy-activated carriers (DilbeadsTM)

The sterol esterase from the ascomycete Ophiostoma piceae was immobilized on novel polyacrylate-based epoxy-activated carriers (DilbeadsTM). Six supports with particle sizes between 120-165 micrometers were prepared varying the composition of monomers, crosslinkers and porogens. Their surface areas and porosities were determined by N2 adsorption and mercury intrusion porosimetry. The pore volumes ranged from 0.63 to 1.32 cm3/g, but only DilbeadsTM RS and NK had narrow pore size distributions (with maxima at 33.5 and 67.0 nm, respectively). The distribution of the enzyme in the support was studied by fluorescence confocal microscopy. The immobilized esterase on DilbeadsTM TA showed a significant pH and thermal stability and was assayed in the continuous hydrolysis of cholesteryl esters -present in the pulp industry process waters-.We thank Mª Teresa Seisdedos (Centro de Investigaciones Biologicas, CSIC) for help with the confocal microscopy. This research was supported by the Spanish Ministry of Education and Science (Projects BIO2002-00337 and BIO2003-00621) and Comunidad de Madrid (Project S-0505/AMB0100). We thank CSIC for a research fellowshipPeer reviewe