The concept of neutrality : a new approach

Purpose: Neutrality is a much debated value in Library and Information Science. The ‘neutrality debate’ is characterised by opinionated discussions in contrasting contexts. The study reported here fills a gap in the literature by bringing these conceptions together holistically, with potential to deepen understanding of LIS neutrality. Methodology: Firstly, a literature review identified conceptions of neutrality reported in LIS literature. Secondly, seven phenomenographic interviews with LIS professionals were conducted across three professional sectors. To maximise variation, each sector comprised at least one interview with a professional of five or fewer years’ experience and one with ten or more years’ experience. Thirdly, conceptions from the literature and interviews were compared for similarities and disparities. Findings: Four conceptions each were found in literature and interviews. In the literature these were labelled: ‘Favourable’, ‘Tacit Value’, ‘Social Institutions’ and ‘Value Laden Profession’, whilst in interviews they were labelled: ‘Core Value’, 'Subservient’, ‘Ambivalent’, and ‘Hidden Values’. The study’s main finding notes the ‘Ambivalent’ conception in interviews is not captured by a largely polarised literature which oversimplifies neutrality’s complexity. To accommodate this complexity, it is suggested that future research should look to reconcile perceptions from either side of the ‘neutral non-neutral divide’ through an inclusive normative framework. Value: This study’s value lies in its descriptive methodology which brings LIS neutrality together in a holistic framework. This framework brings a contextual awareness to LIS neutrality lacking in previous research. This awareness has the potential to change the tone of the LIS neutrality debate

Interlending and resource-sharing in UK public libraries: a mixed methods study

This paper presents the results of a mixed methods study of interlending and resource sharing in UK public libraries, based on the results of a survey distributed to both senior library managers and interlending staff, and in-depth follow-up interviews with twenty respondents. We present an analysis of perspectives towards rates of interlending, the rationales and strategies for providing the service, the perceived value for money offered by various interlending schemes, the impact of the current digital environment, and views on the future of interlending in the UK. Our findings suggest that while interlending services are undoubtedly threatened by the drastic cuts to public library funding, and that demand for the service is more generally in decline, resource sharing is viewed by some as a potential means of mitigating the effects of increasingly limited acquisitions budgets, and ensuring the public library system continues to provide access to a wide range of resources for its users

Developmental delay and progressive seizures in 2-month-old child with diffuse MRI abnormalities

2 month-old infant presented with seizures, radiological findings of diffuse elevated T2 signal with frontal lobe sparing and extensive symmetrical post contrast enhancement. At autopsy, the brain stem was pale and atrophic, with areas of cystic degeneration. Medullary sections showed perivascular Rosenthal fibre deposition

Dietary interventions for maintaining cognitive function in cognitively healthy people in mid life

This is the protocol for a review and there is no abstract. The objectives are as follows: In this review we will set out to evaluate the effects of dietary interventions for maintaining cognitive function in cognitively healthy people in mid-life and preventing cognitive decline in late life

Scanning Quantum Decoherence Microscopy

The use of qubits as sensitive magnetometers has been studied theoretically and recent demonstrated experimentally. In this paper we propose a generalisation of this concept, where a scanning two-state quantum system is used to probe the subtle effects of decoherence (as well as its surrounding electromagnetic environment). Mapping both the Hamiltonian and decoherence properties of a qubit simultaneously, provides a unique image of the magnetic (or electric) field properties at the nanoscale. The resulting images are sensitive to the temporal as well as spatial variation in the fields created by the sample. As an example we theoretically study two applications of this technology; one from condensed matter physics, the other biophysics. The individual components required to realise the simplest version of this device (characterisation and measurement of qubits, nanoscale positioning) have already been demonstrated experimentally.Comment: 11 pages, 5 low quality (but arXiv friendly) image

Fluorescence resonance energy transfer between organic dyes adsorbed onto nano-clay and Langmuir-Blodgett (LB) films

In this communication we investigate two dyes N,N' -dioctadecyl thiacyanine perchlorate (NK) and octadecyl rhodamine B chloride (RhB) in Langmuir and Langmuir-Blodgett (LB) films with or with out a synthetic clay laponite. Observed changes in isotherms of RhB in absence and presence of nano-clay platelets indicate the incorporation of clay platelets onto RhB-clay hybrid films. AFM image confirms the incorporation of clay in hybrid films. FRET was observed in clay dispersion and LB films with and without clay. Efficiency of energy transfer was maximum in LB films with clay.Comment: 15 pages 5 figures, 1 tabl

Topography and instability of monolayers near domain boundaries

We theoretically study the topography of a biphasic surfactant monolayer in the vicinity of domain boundaries. The differing elastic properties of the two phases generally lead to a nonflat topography of ``mesas'', where domains of one phase are elevated with respect to the other phase. The mesas are steep but low, having heights of up to 10 nm. As the monolayer is laterally compressed, the mesas develop overhangs and eventually become unstable at a surface tension of about K(dc)^2 (dc being the difference in spontaneous curvature and K a bending modulus). In addition, the boundary is found to undergo a topography-induced rippling instability upon compression, if its line tension is smaller than about K(dc). The effect of diffuse boundaries on these features and the topographic behavior near a critical point are also examined. We discuss the relevance of our findings to several experimental observations related to surfactant monolayers: (i) small topographic features recently found near domain boundaries; (ii) folding behavior observed in mixed phospholipid monolayers and model lung surfactants; (iii) roughening of domain boundaries seen under lateral compression; (iv) the absence of biphasic structures in tensionless surfactant films.Comment: 17 pages, 9 figures, using RevTeX and epsf, submitted to Phys Rev

Development of a Nanoparticle-Embedded Chitosan Sponge for Topical and Local Administration of Chemotherapeutic Agents

The following work describes the development of a novel noninvasive transmucosal drug delivery system, the chitosan sponge matrix (CSM). It is composed of cationic chitosan (CS) nanoparticles (NPs) that encapsulate cisplatin (CDDP) embedded within a polymeric mucoadhesive CS matrix. CSM is designed to swell up when exposed to moisture, facilitating release of the NPs via diffusion across the matrix. CSM is intended to be administered topically and locally to mucosal tissues, with its initial indication being oral cancer (OC). Currently, intravenous (IV) administered CDDP is the gold standard chemotherapeutic agent used in the treatment of OC. However, its clinical use has been limited by its renal and hemotoxicity profile. We aim to locally administer CDDP via encapsulation in CS NPs and deliver them directly to the oral cavity with CSM. It is hypothesized that such a delivery device will greatly reduce any systemic toxicity and increase antitumor efficacy. This paper describes the methods for developing CSM and maintaining the integrity of CDDP NPs embedded in the CSM