2,831 research outputs found
Fission decay of N = Z nuclei at high angular momentum: Zn
Using a unique two-arm detector system for heavy ions (the BRS, binary
reaction spectrometer) coincident fission events have been measured from the
decay of Zn compound nuclei formed at 88MeV excitation energy in the
reactions with Ar beams on a Mg target at Ar) =
195 MeV. The detectors consisted of two large area position sensitive (x,y) gas
telescopes with Bragg-ionization chambers. From the binary coincidences in the
two detectors inclusive and exclusive cross sections for fission channels with
differing losses of charge were obtained. Narrow out-of-plane correlations
corresponding to coplanar decay are observed for two fragments emitted in
binary events, and in the data for ternary decay with missing charges from 4 up
to 8. After subtraction of broad components these narrow correlations are
interpreted as a ternary fission process at high angular momentum through an
elongated shape. The lighter mass in the neck region consists dominantly of two
or three-particles. Differential cross sections for the different mass splits
for binary and ternary fission are presented. The relative yields of the binary
and ternary events are explained using the statistical model based on the
extended Hauser-Feshbach formalism for compound nucleus decay. The ternary
fission process can be described by the decay of hyper-deformed states with
angular momentum around 45-52 .Comment: 23 pages, 25 figure
Nucleon electromagnetic form factors in two-flavour QCD
We present results for the nucleon electromagnetic form factors, including
the momentum transfer dependence and derived quantities (charge radii and
magnetic moment). The analysis is performed using O(a) improved Wilson fermions
in Nf=2 QCD measured on the CLS ensembles. Particular focus is placed on a
systematic evaluation of the influence of excited states in three-point
correlation functions, which lead to a biased evaluation, if not accounted for
correctly. We argue that the use of summed operator insertions and fit
ans\"atze including excited states allow us to suppress and control this
effect. We employ a novel method to perform joint chiral and continuum
extrapolations, by fitting the form factors directly to the expressions of
covariant baryonic chiral effective field theory. The final results for the
charge radii and magnetic moment from our lattice calculations include, for the
first time, a full error budget. We find that our estimates are compatible with
experimental results within their overall uncertainties.Comment: 22 pages, 10 figures, citations modifie
The EMT-activator ZEB1 is unrelated to platinum drug resistance in ovarian cancer but is predictive of survival
The IGROVCDDP cisplatin-resistant ovarian cancer cell line is an unusual model, as it is also cross-resistant to paclitaxel. IGROVCDDP, therefore, models the resistance phenotype of serous ovarian cancer patients who have failed frontline platinum/taxane chemotherapy. IGROVCDDP has also undergone epithelial-mesenchymal transition (EMT). We aim to determine if alterations in EMT-related genes are related to or independent from the drug-resistance phenotypes. EMT gene and protein markers, invasion, motility and morphology were investigated in IGROVCDDP and its parent drug-sensitive cell line IGROV-1. ZEB1 was investigated by qPCR, Western blotting and siRNA knockdown. ZEB1 was also investigated in publicly available ovarian cancer gene-expression datasets. IGROVCDDP cells have decreased protein levels of epithelial marker E-cadherin (6.18-fold, p = 1.58e−04) and higher levels of mesenchymal markers vimentin (2.47-fold, p = 4.43e−03), N-cadherin (4.35-fold, p = 4.76e−03) and ZEB1 (3.43-fold, p = 0.04). IGROVCDDP have a spindle-like morphology consistent with EMT. Knockdown of ZEB1 in IGROVCDDP does not lead to cisplatin sensitivity but shows a reversal of EMT-gene signalling and an increase in cell circularity. High ZEB1 gene expression (HR = 1.31, n = 2051, p = 1.31e−05) is a marker of poor overall survival in high-grade serous ovarian-cancer patients. In contrast, ZEB1 is not predictive of overall survival in high-grade serous ovarian-cancer patients known to be treated with platinum chemotherapy. The increased expression of ZEB1 in IGROVCDDP appears to be independent of the drug-resistance phenotypes. ZEB1 has the potential to be used as biomarker of overall prognosis in ovarian-cancer patients but not of platinum/taxane chemoresistance
Nucleon axial form factors from two-flavour Lattice QCD
We present preliminary results on the axial form factor and the
induced pseudoscalar form factor of the nucleon. A systematic
analysis of the excited-state contributions to form factors is performed on the
CLS ensemble `N6' with and lattice spacing . The relevant three-point functions were computed with
source-sink separations ranging from to $t_s \sim \
1.4 \ \text{fm}$. We observe that the form factors suffer from non-trivial
excited-state contributions at the source-sink separations available to us. It
is noted that naive plateau fits underestimate the excited-state contributions
and that the method of summed operator insertions correctly accounts for these
effects.Comment: 7 pages, 12 figures; talk presented at Lattice 2014 -- 32nd
International Symposium on Lattice Field Theory, 23-28 June, 2014, Columbia
University New York, N
Constraining quasar host halo masses with the strength of nearby Lyman-alpha forest absorption
Using cosmological hydrodynamic simulations we measure the mean transmitted
flux in the Lyman alpha forest for quasar sightlines that pass near a
foreground quasar. We find that the trend of absorption with pixel-quasar
separation distance can be fitted using a simple power law form including the
usual correlation function parameters r_{0} and \gamma so that ( = \sum
exp(-tau_eff*(1+(r/r_{0})^(-\gamma)))). From the simulations we find the
relation between r_{0} and quasar mass and formulate this as a way to estimate
quasar host dark matter halo masses, quantifying uncertainties due to
cosmological and IGM parameters, and redshift errors. With this method, we
examine data for ~3000 quasars from the Sloan Digital Sky Survey (SDSS) Data
Release 3, assuming that the effect of ionizing radiation from quasars (the
so-called transverse proximity effect) is unimportant (no evidence for it is
seen in the data.) We find that the best fit host halo mass for SDSS quasars
with mean redshift z=3 and absolute G band magnitude -27.5 is log10(M/M_sun) =
12.48^{+0.53}_{-0.89}. We also use the Lyman-Break Galaxy (LBG) and Lyman alpha
forest data of Adelberger et al in a similar fashion to constrain the halo mass
of LBGs to be log10(M/M_sun) = 11.13^{+0.39}_{-0.55}, a factor of ~20 lower
than the bright quasars. In addition, we study the redshift distortions of the
Lyman alpha forest around quasars, using the simulations. We use the quadrupole
to monopole ratio of the quasar-Lyman alpha forest correlation function as a
measure of the squashing effect. We find that this does not have a measurable
dependence on halo mass, but may be useful for constraining cosmic geometry.Comment: 10 pages, 11 figures, submitted to MNRA
Quantum Theory of Cavity-Assisted Sideband Cooling of Mechanical Motion
We present a fully quantum theory describing the cooling of a cantilever
coupled via radiation pressure to an illuminated optical cavity. Applying the
quantum noise approach to the fluctuations of the radiation pressure force, we
derive the opto-mechanical cooling rate and the minimum achievable phonon
number. We find that reaching the quantum limit of arbitrarily small phonon
numbers requires going into the good cavity (resolved phonon sideband) regime
where the cavity linewidth is much smaller than the mechanical frequency and
the corresponding cavity detuning. This is in contrast to the common assumption
that the mechanical frequency and the cavity detuning should be comparable to
the cavity damping.Comment: 5 pages, 2 figure
Plasma-Induced Frequency Chirp of Intense Femtosecond Lasers and Its Role in Shaping High-Order Harmonic Spectral Lines
We investigate the self-phase modulation of intense femtosecond laser pulses
propagating in an ionizing gas and its effects on collective properties of
high-order harmonics generated in the medium. Plasmas produced in the medium
are shown to induce a positive frequency chirp on the leading edge of the
propagating laser pulse, which subsequently drives high harmonics to become
positively chirped. In certain parameter regimes, the plasma-induced positive
chirp can help to generate sharply peaked high harmonics, by compensating for
the dynamically-induced negative chirp that is caused by the steep intensity
profile of intense short laser pulses.Comment: 5 pages, 5 figure
The high-lying Li levels at excitation energy around 21 MeV
The H+He cluster structure in Li was investigated by the
H(,H He)n kinematically complete experiment at the incident
energy = 67.2 MeV. We have observed two resonances at =
21.30 and 21.90 MeV which are consistent with the He(H, )Li
analysis in the Ajzenberg-Selove compilation. Our data are compared with the
previous experimental data and the RGM and CSRGM calculations.Comment: 12 pages, 6 figures. Accepted for publication in J. Phys. Soc. Jp
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