Verbal Memory and IQ Predict Adaptive Behavior in Children and Adolescents with High-Functioning Autism Spectrum Disorders

Adaptive deficits are commonly found in high functioning autism spectrum disorders (HF-ASD) despite of cognitive potential. Most studies have focused on the relationships between adaptive behavior and intellectual quotient (IQ) and have used correlations to study relationships between them. Few studies have analyzed cognitive variables other than IQ as potential predictors of adaptive behavior in HF-ASD using regression methods. This study aimed to analyze the impact of several cognitive variables on adaptive behavior in a sample of children and adolescents with HF-ASD. METHODS: Sample included 16 child and adolescent boys with HF-ASD (age between 7-17 years). Cognitive assessment included measures of general intelligence, visual memory, verbal memory, working memory and problem solving/flexibility tests. Vineland Adaptive Behavior Scales (VABS) was used to evaluate adaptive behavior. To establish the predictive capacity of the cognitive variables for adaptive functioning, linear regression models were fitted for each adaptive domain using a stepwise method. RESULTS: Verbal memory and IQ emerged as the main independent predictors for VABS adaptive scores. The 41% of the variance in Communication was predicted by IQ. The 35% of the variance in Daily Living Skills was predicted by verbal memory. Almost half of the variance in Socialization was predicted by both, verbal memory and IQ (49%). No other cognitive functions were associated with adaptive scores. CONCLUSIONS: The results highlight the strong impact of IQ and verbal memory on adaptive behavior in HF-ASD patients. These findings could contribute to identify potential targets of intervention

Conscientious Objection in Spanish Podiatrists Students: A Questionnaire Survey

[Abstract] Objective: To explore attitudes towards conscientious objections among podiatrists students in Spain. Methods: Podiatrists students at University of A Coruña, King Rey Juan Carlos University, University of Sevilla and Complutense University of Madrid were emailed a link to complete an anonymous online questionnaire, hosted by an online survey company. A total of 432 podiatrists students responded. Results: Nearly half of the students in this survey stated that they believed in the right of podiatrist to conscientiously object to any procedure. Demand for the right to conscientiously object is greater in Roman Catholic podiatrists students when compared with other groups of religious podiatrists students. Discussion: Examining patients and podiatric treatments continues to be controversy issues among podiatrists students and this may contribute to the looming crisis in podiatry services over next years. This project sheds some light on how future podiatrist view some of their ethical rights and obligations. Using empirical evidence, it reveals that conscientious objection is an issue in the Spain podiatrists student body today. These data could help anticipate problems that may arise when these podiatrists students qualify and practice podiatry in the community. Conclusion: Clearer guidance is needed for podiatrists students about the issue of conscientious objection at podiatry school.[Resumen] Objetivo: Explorar actitudes hacia la objeción de conciencia entre estudiantes de podología en España. Métodos: Se realizó un cuestionario anónimo online vía email a estudiantes de podología de la Universidad del Rey Juan Carlos de la Coruña, la Universidad de Sevilla y la Universidad Complutense de Madrid, organizado por una empresa de encuestas online. Respondieron un total de 432 estudiantes de podología. Resultados: Casi la mitad de los estudiantes afirmaron en la encuesta que creían en el derecho del podólogo a la objeción de conciencia en cualquier procedimiento. La exigencia del derecho a objeción de conciencia fue mayor en estudiantes de podología católicos que en otros grupos de otras religiones. Discusión: Examinar a pacientes y los tratamientos de podología continúan siendo temas controversiales entre los estudiantes de podología y esto puede que contribuya a la inminente crisis en servicios de pedicura en los próximos años. Este proyecto derrama algo de luz sobre como futuros podólogos ven algunos de sus derechos y obligaciones éticas. Usando evidencia científica, revela que la objeción de conciencia es un tema para los estudiantes de podología en España hoy día. Estos datos pueden ayudar a anticipar problemas que puedan surgir cuando estos estudiantes de podología califiquen y practiquen podología en la comunidad. Conclusión: Se necesitan pautas más claras para estudiantes de podología sobre el tema de objeción de conciencia en la Escuela de Podología.[Resumo] Objetivo: Explorar atitudes com relação à objeção de consciência entre os estudantes de podologia na Espanha. Método: Aos estudantes de podologia da Universidade Universidade Rei Juan Carlos, de Corunha, da Universidade de Sevilla e da Universidade Complutense de Madri foram enviados por email um link para completar um questionário online anônimo, hospedado por uma empresa de pesquisa on-line. Um total de 432 alunos de podologia responderam. Resultados: Quase metade dos alunos nesta pesquisa afirmaram que acreditavam no direito de podólogo se opor conscientemente a qualquer procedimento. A demanda para o direito de se opor conscientemente é maior em estudantes católicos romanos, quando comparado com outros grupos religiosos de estudantes. Discussão: O exame de pacientes e tratamentos podiátricos continuam a ser problema de controvérsia entre os alunos de podologia e isso pode contribuir para a crise iminente nos serviços de podologia para os próximos anos. Este projeto lança alguma luz sobre a forma de o futuro podólogo conhecer alguns dos seus direitos e obrigações éticas. Usando a evidência empírica, revela que a objeção de consciência é um problema no corpo discente de podologia da Espanha, hoje. Estes dados poderiam ajudar a antecipar problemas que podem surgir quando esses estudantes de podología se qualificarem e praticarem a podologia na comunidade. Conclusão: Orientação mais esclarecida é necessária para alunos de podologia sobre a questão da objeção de consciência no curso de graduação

Distortion-free sensing of neural activity using graphene transistors

Graphene solution-gated field-effect transistors (g-SGFETs) are promising sensing devices to transduce electrochemical potential signals in an electrolyte bath. However, distortion mechanisms in g-SGFET, which can affect signals of large amplitude or high frequency, have not been evaluated. Here, a detailed characterization and modeling of the harmonic distortion and non-ideal frequency response in g-SGFETs is presented. This accurate description of the input-output relation of the g-SGFETs allows to define the voltage- and frequency-dependent transfer functions, which can be used to correct distortions in the transduced signals. The effect of signal distortion and its subsequent calibration are shown for different types of electrophysiological signals, spanning from large amplitude and low frequency cortical spreading depression events to low amplitude and high frequency action potentials. The thorough description of the distortion mechanisms presented in this article demonstrates that g-SGFETs can be used as distortion-free signal transducers not only for neural sensing, but also for a broader range of applications in which g-SGFET sensors are used

The QUIJOTE experiment: project overview and first results

QUIJOTE (Q-U-I JOint TEnerife) is a new polarimeter aimed to characterize the polarization of the Cosmic Microwave Background and other Galactic and extragalactic signals at medium and large angular scales in the frequency range 10-40 GHz. The multi-frequency (10-20~GHz) instrument, mounted on the first QUIJOTE telescope, saw first light on November 2012 from the Teide Observatory (2400~m a.s.l). During 2014 the second telescope has been installed at this observatory. A second instrument at 30~GHz will be ready for commissioning at this telescope during summer 2015, and a third additional instrument at 40~GHz is now being developed. These instruments will have nominal sensitivities to detect the B-mode polarization due to the primordial gravitational-wave component if the tensor-to-scalar ratio is larger than r=0.05.Comment: To appear in "Highlights of Spanish Astrophysics VIII", Proceedings of the XI Scientific Meeting of the Spanish Astronomical Society, Teruel, Spain (2014

QUIJOTE-CMB experiment: a technical overview

The QUIJOTE-CMB experiment (Q-U-I JOint TEnerife CMB experiment) is an ambitious project to obtain polarization measurements of the sky microwave emission in the 10 to 47 GHz range. With this aim, a pair of 2,5m telescopes and three instruments are being sited at the Teide Observatory, in Tenerife (Canary Islands, Spain). The first telescope and the first instrument (the MFI: Multi Frequency Instrument) are both already operating in the band from 10 to 20 GHz, since November 2012. The second telescope and the second instrument (TGI: Thirty GHz instrument) is planned to be in commissioning by the end of summer 2014, covering the range of 26 to 36 GHz. After that, a third instrument named FGI (Forty GHz instrument) will be designed and manufactured to complete the sky survey in the frequency range from 37 to 47 GHz. In this paper we present an overview of the whole project current status, from the technical point of view

The QUIJOTE TGI

The QUIJOTE TGI instrument is currently being assembled and tested at the IAC in Spain. The TGI is a 31 pixel 26-36 GHz polarimeter array designed to be mounted at the focus of the second QUIJOTE telescope. This follows a first telescope and multi-frequency instrument that have now been observing almost 2 years. The polarimeter design is based on the QUIET polarimeter scheme but with the addition of an extra 90º phase switch which allows for quasiinstantaneous complete QUI measurements through each detector. The advantage of this is a reduction in the systematics associated with differencing two independent radiometer channels. The polarimeters are split into a cold front end and a warm back end. The back end is a highly integrated design by engineers at DICOM. It is also sufficiently modular for testing purposes. In this presentation the high quality wide band components used in the optical design (also designed in DICOM) are presented as well as the novel cryogenic modular design. Each polarimeter chain is accessible individually and can be removed from the cryostat and replaced without having to move the remaining pixels. The optical components work over the complete Ka band showing excellent performance. Results from the sub unit measurements are presented and also a description of the novel calibration technique that allows for bandpass measurement and polar alignment. Terrestrial Calibration for this instrument is very important and will be carried out at three points in the commissioning phase: in the laboratory, at the telescope site and finally a reduce set of calibrations will be carried out on the telescope before measurements of extraterrestrial sources begin. The telescope pointing model is known to be more precise than the expected calibration precision so no further significant error will be added through the telescope optics. The integrated back-end components are presented showing the overall arrangement for mounting on the cryostat. Many of the microwave circuits are in-house designs with performances that go beyond commercially available products. Individual component performance is be presented showing for each of the sub modules

QUIJOTE Experiment: status of telescopes and instrumentation

The QUIJOTE Experiment (Q-U-I JOint TEnerife) is a combined operation of two telescopes and three instruments working in the microwave band to measure the polarization of the Cosmic Microwave Background (CMB) from the northern hemisphere, at medium and large angular scales. The experiment is located at the Teide Observatory in Tenerife, one of the seven Canary Islands (Spain). The project is a consortium maintained by several institutions: the Instituto de Astrofísica de Canarias (IAC), the Instituto de Física de Cantabria (IFCA), the Communications Engineering Department (DICOM) at Universidad de Cantabria, and the Universities of Manchester and Cambridge. The consortium is led by the IAC

Treatment of symptomatic macromastia in a breast unit

BACKGROUND: Patients suffering from symptomatic macromastia are usually underserved, as they have to put up with very long waiting lists and are usually selected under restrictive criteria. The Oncoplastic Breast Surgery subspeciality requires a cross-specialty training, which is difficult, in particular, for trainees who have a background in general surgery, and not easily available. The introduction of reduction mammaplasty into a Breast Cancer Unit as treatment for symptomatic macromastia could have a synergic effect, making the scarce therapeutic offer at present available to these patients, who are usually treated in Plastic Departments, somewhat larger, and accelerating the uptake of oncoplastic training as a whole and, specifically, the oncoplastic breast conserving procedures based on the reduction mammaplasty techniques such as displacement conservative techniques and onco-therapeutic mammaplasty. This is a retrospective study analyzing the outcome of reduction mammaplasty for symptomatic macromastia in our Breast Cancer Unit. METHODS: A cohort study of 56 patients who underwent bilateral reduction mammaplasty at our Breast Unit between 2005 and 2009 were evaluated; morbidity and patient satisfaction were considered as end points. Data were collected by reviewing medical records and interviewing patients. RESULTS: Eight patients (14.28%) presented complications in the early postoperative period, two of them being reoperated on. The physical symptoms disappeared or significantly improved in 88% of patients and the degree of satisfaction with the care process and with the overall outcome were really high. CONCLUSION: Our experience of the introduction of reduction mammaplasty in our Breast Cancer Unit has given good results, enabling us to learn the use of different reduction mammaplasty techniques using several pedicles which made it possible to perform oncoplastic breast conserving surgery. In our opinion, this management policy could bring clear advantages both to patients (large-breasted and those with a breast cancer) and surgeons

Seasonal and spatial variability in condition of age-0+ Argentine hake Merluccius hubbsi Marini, 1933, in the San Jorge Gulf (Argentina): A bottom-up perspective

In the north Patagonian region of the Argentinean Continental Shelf, the San Jorge Gulf (SJG; 45°‐47°S, 65°30ʹ‐67°30ʹW) is the main nursery ground of age‐0+ Argentine hake Merluccius hubbsi Marini, 1933, one of the most important fishery resources in Argentina. The gulf exhibits strong seasonal and spatial fluctuations in environmental features, which might affect survival of age‐0+ individuals and recruitment to the adult population. Our main goal was to evaluate the seasonal and spatial dynamics of their nutritional status within the SJG in winter 2016, spring 2016 and summer 2017. Condition indices (relative condition factor Kn, hepatosomatic index HSI and liver lipid content %L) and diet information (feeding incidence and relative importance of prey) were combined with physical (temperature and salinity) and biological (satellite chlorophyll‐a concentration; chl‐a) data. Age‐0+ condition indices and prey intake showed significant seasonal variations, with minimum values in winter, intermediate in summer and maximum in spring, strongly coupled to the mean chl‐a concentration in each season. Herbivorous euphausiids Euphausia spp. were the preferred prey along the study period. A bottom‐up effect on condition of age‐0+ hake is suggested, manifested as lower condition values in winter, the less productive season. Spatially, better conditioned individuals matched sectors of the gulf where chl‐a concentrations were higher, coupled to the presence of frontal systems. Monitoring age‐0+ hake nutritional status is relevant in the current global change scenario, which might modify phytoplankton biomass and composition and, consequently, the herbivorous zooplankton abundances.Fil: Temperoni, Brenda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigaciones Marinas y Costeras. Subsede Instituto Nacional de Investigación y Desarrollo Pesquero; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Marinas y Costeras. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Marinas y Costeras; ArgentinaFil: Massa, Agueda Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mar del Plata. Instituto de Investigaciones Marinas y Costeras. Subsede Instituto Nacional de Investigación y Desarrollo Pesquero; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Marinas y Costeras. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Marinas y Costeras; ArgentinaFil: Martos, Patricia. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Ciencias Marinas; ArgentinaFil: Marrari, Marina. Ministerio de Defensa. Armada Argentina. Servicio de Hidrografía Naval. Departamento Oceanografía; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin