54 research outputs found
Los juegos de cooperación como estrategia metodológica para la disminución de la agresividad en los niños de grado cuarto del IED Tabora Sede B
Se presenta un documento dividido en diez capítulos en los que se aborda un análisis profundo de las teorías desarrolladas a partir de la agresividad manifiesta en los escenarios educativos y las alternativas que se han creado y probado a lo largo de la historia para reducir los niveles de agresividad. El primer elemento que se encuentra es la descripción del problema de investigación, en donde se presentan los antecedentes y la el problema para terminar con la formulación de una pregunta problema que fue la que se intentó resolver a lo largo de la investigación. En seguida se muestra la justificación y los objetivos que se consideraron en la resolución de la pregunta para dar paso al cuarto capítulo que reúne los conceptos definidos para el trabajo de investigación en un aparte denominado Marco teórico; en éste se aborda el concepto de agresión desde los aspectos relacionados con los tipos de agresión, las posibles causas de la misma y los escenarios de la sociedad en donde se da con mayor frecuencia; continúa con los elementos de la sociomotricidad analizados desde la estrategia motriz y lo que esta corriente ha representado como alternativa desde la educación física para la educación de la no violencia, este capítulo finaliza con los juegos de cooperación como una de las mejores alternativas para aplicar en la clase de educación física.
El capítulo cinco describe el marco institucional que no es más que la política educativa de la Institución Educativa Distrital Tabora Sede B- Santa María del Lago, que fue el lugar en donde se desarrolló la investigación. El capítulo seis presenta la estrategia metodológica desde el planteamiento teórico de la investigación holística, pasando por el diseño de los instrumentos, las categorías de análisis, la población y el proceso general de la investigación. El siguiente aparte presenta la propuesta sociomotriz para reducir la agresividad, que se constituye en el elemento innovador de este trabajo analizado. Esta propuesta se presenta a partir de la justificación, los objetivos, los contenidos, la evaluación y los recursos necesarios para la implementación de la propuesta en cualquier centro educativo. La recolección de la información se describe en un capítulo distinto y en ella relacionan las fases que se deben considerar si se hace uso de la investigación holística para concluir en el análisis de la información y dar así por terminado el documento con unas conclusiones y la bibliografía revisada
Toxicidad relacionada con el tratamiento para el cáncer en adultos mayores. Revisión de la literatura
Las patologías de origen tumoral son más frecuentes en la población adulta
mayor; no obstante, el que dicha población tenga menos oportunidades de
acceder a estudios diagnósticos e intervenciones terapéuticas impacta en
la respuesta clínica a las distintas terapias que existen para tratar el cáncer,
sumado al riesgo de toxicidad con la quimioterapia tradicional o con los
esquemas de la inmunoterapia o terapia dirigida, que pueden generar
toxicidad en menor grado, principalmente cardiovascular, hematológica,
gastrointestinal y de piel. Teniendo en cuenta lo anterior se ha intentado avanzar en la predicción del riesgo de toxicidad a la quimiorradioterapia
con diferentes modelos basados en cálculos clínicos y paraclínicos, muchos
de los cuales se desprenden de la valoración geriátrica. Sin embargo, de
manera global, estas herramientas de predicción del riesgo de toxicidad
tienen varias limitaciones, como la falta de precisión al calcular el riesgo
de toxicidad grave asociada a la quimiorradioterapia y muchas no están
validadas, por lo que muchos estudios concluyen que se necesitan modelos
más precisos a la hora de predecir dicho riesgo. No obstante, se ha
evidenciado que combinar varias herramientas (funcionales y clínicas)
mejora los resultados al modificar el plan de atención del paciente adulto
mayor con cáncer.Pathologies of tumor origin are more frequent in the older adult
population, however said population has fewer opportunities to access
diagnostic studies and therapeutic interventions, not only due to the
age and stage of the cancer, but also because they have conditions of
aging such as decreased functional reserve, multiple pathologies, cognitive
disorders, or lack of social support that impact on the clinical response
to the different therapies that exist to treat cancer. In addition to this,
the risk of toxicity conferred by the various cancer treatments, which
leads to a more careful evaluation of the type of therapy, the dose,
and the benefit of starting it. With the discovery of new therapies for cancer management, we not only face the risk of toxicity
with traditional chemotherapy, but also the schemes
developed in recent times, such as immunotherapy or
targeted therapy, which can mainly generate toxicity to
a lesser degree. cardiovascular, gastrointestinal and skin
hematological. Taking into account the above, an attempt
has been made to advance in the prediction of the
risk of toxicity to chemo-radiotherapy, counting to date
with different models based on clinical and paraclinical
calculations, many of these criteria that come out of
these tools are derived from the assessment geriatric
(GV), we find tools to evaluate functional performance,
cognitive status, social support, which provides valuable
and comprehensive information for decision-making not
only therapeutic, as well as models that include clinical
and paraclinical parameters such as the CRASH tool
which predicts non-hematological and joint hematological
toxicity and the CARG tool that predicts joint toxicity.
However, globally, these toxicity risk prediction tools have
several limitations, such as the lack of precision when
calculating the risk of severe toxicity associated with
chemo-radiotherapy, many are not validated, so many
studies conclude that models are needed more accurate
when predicting such risk. However, it has been shown that
combining various tools (functional and clinical) improves
results on many occasions by modifying the care plan for
the elderly patient with cancer.Revista Nacional - Indexad
Evaluación económica y propuesta de desarrollo logístico para la factibilidad de montaje de un centro de distribución y comercialización de elementos de seguridad industrial en la ciudad de Yopal-Casanare.
El presente proyecto va dirigido con el fin básico de generar una propuesta a la empresa Dotacenter S.A.S, para la implementación de un centro de distribución y comercialización de sus productos en la ciudad de Yopal.Especialista en Gerencia LogísticaEspecializació
CONFIGURACIÓN DE NETHSERVER PARA LA INSTALACIÓN DE SERVICIOS
En este artículo, se detalla el proceso
de instalación y configuración de diversos servicios en una
distribución Nethserver 7.8.2003. Este paso a paso aborda la
puesta en marcha de cada servicio solicitado en los módulos
temáticos del curso del diplomado Linux, que comprenden
desde el 1 hasta el 5.
Las temáticas cubiertas incluyen la configuración de
servicios fundamentales, como DHCP Server, DNS Server y
Controlador de Dominio, así como la implementación de
servicios adicionales como Proxy, Cortafuegos, File Server,
Print Server y servicios de VPN. Este artículo proporciona
una guía detallada para lograr una configuración exitosa de
cada servicio, facilitando la comprensión y aplicación
práctica de los conceptos aprendidos en el diplomado Linux.This article outlines the process of
installing and configuring various services on a Nethserver
7.8.2003 distribution. This step-by-step guide addresses the
implementation of each requested service in the thematic
modules of the Linux diploma course, covering modules 1
through 5.
The covered topics include the configuration of
fundamental services such as DHCP Server, DNS Server, and
Domain Controller, as well as the implementation of additional
services like Proxy, Firewall, File Server, Print Server, and
VPN services. This article provides a detailed guide for
achieving a successful configuration of each service,
facilitating the understanding and practical application of the
concepts learned in the Linux diploma course
An 8-gene qRT-PCR-based gene expression score that has prognostic value in early breast cancer
<p>Abstract</p> <p>Background</p> <p>Gene expression profiling may improve prognostic accuracy in patients with early breast cancer. Our objective was to demonstrate that it is possible to develop a simple molecular signature to predict distant relapse.</p> <p>Methods</p> <p>We included 153 patients with stage I-II hormonal receptor-positive breast cancer. RNA was isolated from formalin-fixed paraffin-embedded samples and qRT-PCR amplification of 83 genes was performed with gene expression assays. The genes we analyzed were those included in the 70-Gene Signature, the Recurrence Score and the Two-Gene Index. The association among gene expression, clinical variables and distant metastasis-free survival was analyzed using Cox regression models.</p> <p>Results</p> <p>An 8-gene prognostic score was defined. Distant metastasis-free survival at 5 years was 97% for patients defined as low-risk by the prognostic score versus 60% for patients defined as high-risk. The 8-gene score remained a significant factor in multivariate analysis and its performance was similar to that of two validated gene profiles: the 70-Gene Signature and the Recurrence Score. The validity of the signature was verified in independent cohorts obtained from the GEO database.</p> <p>Conclusions</p> <p>This study identifies a simple gene expression score that complements histopathological prognostic factors in breast cancer, and can be determined in paraffin-embedded samples.</p
Influence of obstructive sleep apnea on systemic inflammation in pregnancy
Background: Obstructive sleep apnea (OSA) is prevalent in pregnancy and it is associated with adverse pregnancy-related outcomes such as gestational diabetes, pre-eclampsia, and low birth weight. Maternal systemic inflammation is proposed to be one of the main intermediate mechanisms. However, the effects of OSA on systemic inflammation are unknown in normal pregnancy. Methods: Women in the 3rd trimester underwent hospital polysomnography to evaluate whether OSA increases systemic inflammation in normal pregnancy and its potential association with adverse fetal outcomes. OSA was defined as an apnea–hypopnea index (AHI) of = 5 h-1. Plasma cytokines levels (TNF-a, IL-1ß, IL-6, IL-8, and IL-10) were determined by multiple immunoassays. Results: We included 11 patients with OSA and 22 women with AHI < 5 h-1, who were homogeneous in age, and body mass index (BMI). Women with OSA had significant higher levels of TNF-a, IL-1ß, IL-8, and IL-10. We found significant correlations between AHI during REM and TNF-a (r = 0.40), IL-1ß (r = 0.36), IL-6 (r = 0.52), IL-8 (r = 0.43), between obstructive apnea index and TNF-a (r = 0.46) and between AHI and IL-1ß (r = 0.43). We also found that CT90% was related to IL-8 (r = 0.37). There were no significant differences in neonatal characteristics; however, we found inverse correlations between TNF-a and IL-8 with birth weight (both r = -0.48), while IL-8 showed a significant inverse relationship with neonatal gestational age (r = -0.48). Conclusions: OSA in our normal pregnancy population was associated with higher systemic inflammation, which was related to obstructive events, especially during REM sleep. Moreover, systemic inflammation was inversely correlated with neonatal birth weight and age
Consumption of caffeinated beverages and kidney function decline in an elderly Mediterranean population with metabolic syndrome
It remains unclear whether caffeinated beverages could have deleterious renal effects in elderly population with underlying comorbid conditions. We investigated the associations between coffee, tea, or caffeine intake and 1-year changes in glomerular filtration rate (eGFR) in a large Spanish cohort of overweight/obese elderly with metabolic syndrome (MetS). This prospective analysis includes 5851 overweight/obese adults (55-75 years) with MetS from the PREDIMED-Plus study. We assessed coffee, tea, and caffeine consumption from a validated food-frequency questionnaire and creatinine-based eGFR using the Chronic Kidney Disease Epidemiology Collaboration equation. Multivariate-adjusted regression models were applied to test associations between baseline coffee, tea, or caffeine intake and 1-year eGFR changes. Caffeinated coffee (> 2 cups/day) and tea (at least 1 cup/day) drinkers had 0.88 and 0.93 mL/min/1.73 m2 greater eGFR decrease respectively, compared to those with less than 1 cup/day of coffee consumption or non-tea drinkers. Furthermore, caffeinated coffee consumption of > 2 cups/day was associated with 1.19-fold increased risk of rapid eGFR decline > 3 mL/min/1.73 m2 (95% CI 1.01-1.41). Similarly, individuals in the highest (median, 51.2 mg/day) tertile of caffeine intake had a 0.87 mL/min/1.73 m2 greater eGFR decrease. Decaffeinated coffee was not associated with eGFR changes. In conclusion, higher consumption of caffeinated coffee, tea, and caffeine was associated with a greater 1-year eGFR decline in overweight/obese adults with MetS
Long daytime napping is associated with increased adiposity and type 2 diabetes in an elderly population with metabolic syndrome
Research examining associations between objectively-measured napping time and type
2 diabetes (T2D) is lacking. This study aimed to evaluate daytime napping in relation to T2D and
adiposity measures in elderly individuals from the Mediterranean region. A cross-sectional analysis of
baseline data from 2190 elderly participants with overweight/obesity and metabolic syndrome, in the
PREDIMED-Plus trial, was carried out. Accelerometer-derived napping was measured. Prevalence
ratios (PR) and 95% confidence intervals (CI) for T2D were obtained using multivariable-adjusted
Cox regression with constant time. Linear regression models were fitted to examine associations of
napping with body mass index (BMI) and waist circumference (WC). Participants napping ≥90 min
had a higher prevalence of T2D (PR 1.37 (1.06, 1.78)) compared with those napping 5 to <30 min per
day. Significant positive associations with BMI and WC were found in those participants napping
≥30 min as compared to those napping 5 to <30 min per day. The findings of this study suggest that
longer daytime napping is associated with higher T2D prevalence and greater adiposity measures in
an elderly Spanish population at high cardiovascular risk
La función ecológica de la propiedad colectiva en los territorios colectivos de las comunidades negras. Caso Yuto cabecera municipal del Atrato, Chocó. Colombia
El trabajo de investigación, fue realizado en el departamento del Chocó, en el municipio del Atrato, su cabecera municipal Yuto: con el objetivo de describir y analizar los determinantes socio-económicos adversos a la posibilidad de garantizar el cumplimiento de la función ecológica de la propiedad, desarrollando 3 objetivos específicos, el primero, diagnosticar participativamente las condiciones actuales del territorio en términos económicos, comunitarios, políticos, institucionales y ambientales, analizar la realidad territorial teniendo en cuenta la normativa respecto al cumplimiento de la función ecológica de la propiedad, y por último, se propuso elementos que faciliten la vinculación de la función ecológica de la propiedad a procesos de ordenamiento territorial| mediante un enfoque participativo en el cual se genero un sentido de pertenencia en las organizaciones, comunidades e instituciones, fortaleciendo la gestión local y haciendo efectiva la participación con responsabilidades compartidas, sujetas de ser evaluadas con resultados en la perspectiva del mejoramiento de las condiciones de vida y la preservación de la naturaleza, teniendo en cuenta, que es un tema no conocido y poco estudiado en el caso de la Comunidades negras, donde no se ha comprendido el valor ecológico, económico y cultural de estos espacios, los cuales son un pilar no solo para el desarrollo sostenible del país so no, para el resto del planeta.The research was conducted in the department of Chocó, in the municipality of Atrato, the municipal Yuto: In order to describe and analyze the socio-economic impacts to the possibility of ensuring compliance with the ecological function of the property, developing 3 specific objectives, the first participatory diagnose the current conditions of the territory in economic, community, political, institutional and environmental, the spatial analysis taking into account the rules regarding compliance with the ecological function of the property, and Finally, it was proposed to facilitate the linking elements of the ecological function of ownership to land use planning processes, through a participatory approach in which generated a sense of ownership in organizations, communities and institutions, strengthening the local management and making effective engagement with shared responsibilities, subject to be evaluated results in the perspective of improving living conditions and preservation of nature, taking into account, which is a subject not known and little studied in the case of the black Communities where no one understands the ecological, economic and cultural development of these spaces, which are a mainstay not only for sustainable development of the country so not for the rest of the planet
Diseño de plan estratégico de comunicación para el gimnasio de crossfit tropa Bogotá
98 páginasEn el presente trabajo se propone desarrollar un plan de comunicaciones para el gimnasio de Crossfit Tropa de la ciudad de Bogotá con el fin de mejorar la comunicación a través de los canales digitales de la organización para la capitalización de públicos objetivos y fortalecimiento de la comunidad de miembros. Para alcanzar este propósito en primer lugar se realizó un diagnóstico con el objetivo de identificar todo tipo de fallas comunicativas tanto a nivel interno como externo. De allí se estableció la necesidad de planear estrategias comunicativas para solucionar y mejorar específicamente sus prácticas de comunicación externa. El desarrollo de este proyecto consta de una investigación de tipo exploratoria y descriptiva de métodos mayormente cuantitativos. Sin embargo, hay espacios en los que los datos cualitativos justifican parte de las estrategias y tácticas propuestas. Las fuentes de información fueron primarias: La fundadora del gimnasio, empleados, atletas e integrantes del lugar y, por último, se realizó una encuesta masiva a personas que se ejercitan en otros espacios o practican diferentes disciplinas. Al igual, se incluyeron personas que residen cerca a la zona del establecimiento para conocer los hábitos de ejercicio que tienen. Por otra parte, fuentes secundarias, libros, investigaciones en internet y archivos físicos y digitales.In the present work is proposed to develop a communications plan for the Crossfit Tropa gym in the city of Bogota in order to improve communication through the organization’s digital channels for the capitalization of target audiences and strengthening of the community of members. In order to achieve this goal, a diagnosis was carried out with the aim of identifying all types of communication failures, both internally and externally. This established the need to plan communication strategies to specifically address and improve their external communication practices. The development of this project consists of exploratory and descriptive research of mostly quantitative methods.
However, there are spaces in which qualitative data justify part of the proposed strategies and tactics. The sources of information were primary: the founder of the gym, employees, athletes and members of the place and, finally, a massive survey was conducted of people who exercise in other spaces or practice different disciplines. Likewise, people who live near the establishment area were included to learn about their exercise habits. On the other hand, secondary sources, books, internet research and physical and digital files.
This work takes 6 fitness centers located in Bogotá as a research reference, especially in places that are close to the Tropa gym, one in the city of Medellín and other establishments that provide aesthetic services. This analysis in order to know and compare the communication strategies, especially in social networks, that they have developed to attract customers. The foregoing, in order to obtain references and make new proposals to the Bogotá Tropa strategy. In addition, the communication strategies of these physical conditioning centers against the conjuncture of COVID - 19 with their clients and target audiences were evaluated.Comunicación Social y PeriodismoComunicador Social y Periodist
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