30 research outputs found
Avaliação da pós-graduação na UFC: as críticas dos coordenadores de programas à CAPES
A presente pesquisa buscou identificar a percepção dos coordenadores de pós-graduação de uma universidade em relação à avaliação de seus programas de pós-graduação promovido pela Capes. O estudo realiza uma incursão na legislação norteadora sobre o tema e nas abordagens teóricas acerca da avaliação educacional e, em específico, da pós-graduação stricto sensu. Trata-se de pesquisa descritiva, qualitativa delineando-se como estudo de caso. Os dados são provenientes de survey que foram submetidos a análise descritiva e análise de conteúdo (qualitativa). O lócus da pesquisa é a UFC e seus programas de pós-graduação avaliados em 2010 e 2013, tendo a participação dos respectivos coordenadores. Os resultados revelam que o modelo de avaliação adotado pela Capes, com base na classificação de programas hierarquizados por notas e peso, é bem aceito. As críticas ao modelo de avaliação concentram-se na padronização dos critérios de avaliação da Capes, que desconsidera as diferenças regionais e com relação ao estímulo à competitividade positiva entre as áreas de conhecimento
Efficacy of 30% and 38% Silver Diamine Fluoride in Arresting Caries Lesions After Different Application Times: An in Vitro Study
Objective: To evaluate the efficacy of silver diamine fluoride (SDF) in arresting dentin caries lesions when applied under different concentrations and times. Material and Methods: Forty-two bovine blocks were selected and fixed in 24-well plates. Each well received a mixed bacterial inoculum added to the culture medium with 5% sucrose. The plates were incubated in microaerophilia (7 days) for caries formation, confirmed by micro-CT (M1). SDF was applied over the carious lesions for different times and concentrations (n=6): SDF 30% - immediate removal, 1 minute and 3 minutes; SDF 38%, - immediate removal, 1 minute and 3 minutes. The group without treatment was the control. Then, the samples were again scanned by micro-CT (M2) and submitted to a second cariogenic challenge for 21 days. Then, a final scan was performed (M3). Results: Mean pH at the culture medium and lesion depth were compared using Kruskal-Wallis and Wilcoxon tests. 38% SDF showed the lowest metabolic activity of the biofilm. All 38% groups and 30% 1 and 3 minutes did not show an increase in mean lesion depth comparing M3 with M1. However, only 30% 3 minutes and 38% 1 and 3 minutes showed a significant reduction of lesion depth. Conclusion: The minimum application time of 30% SDF to arrest dentin caries lesion was 1 minute, while 38% SDF arrested with application and immediate removal
Amblyomma sculptum Salivary PGE2 Modulates the Dendritic Cell-Rickettsia rickettsii Interactions in vitro and in vivo
Amblyomma sculptum is an important vector of Rickettsia rickettsii, causative agent of Rocky Mountain spotted fever and the most lethal tick-borne pathogen affecting humans. To feed on the vertebrate host's blood, A. sculptum secretes a salivary mixture, which may interact with skin resident dendritic cells (DCs) and modulate their function. The present work was aimed at depicting the A. sculptum saliva-host DC network and the biochemical nature of the immunomodulatory component(s) involved in this interface. A. sculptum saliva inhibits the production of inflammatory cytokines by murine DCs stimulated with LPS. The fractionation of the low molecular weight salivary content by reversed-phase chromatography revealed active fractions eluting from 49 to 55% of the acetonitrile gradient. Previous studies suggested that this pattern of elution matches with that observed for prostaglandin E2 (PGE2) and the molecular identity of this lipid mediator was unambiguously confirmed by a new high-resolution mass spectrometry methodology. A productive infection of murine DCs by R. rickettsii was demonstrated for the first time leading to proinflammatory cytokine production that was inhibited by both A. sculptum saliva and PGE2, a result also achieved with human DCs. The adoptive transfer of murine DCs incubated with R. rickettsii followed by treatment with A. sculptum saliva or PGE2 did not change the cytokine profile associated to cellular recall responses while IgG2a-specific antibodies were decreased in the serum of these mice. Together, these findings emphasize the role of PGE2 as a universal immunomodulator of tick saliva. In addition, it contributes to new approaches to explore R. rickettsii-DC interactions both in vitro and in vivo
Anais do V Encontro Brasileiro de Educomunicação: Educação midiática e políticas públicas
A presente coletânea, que chega ao público através de um suporte digital, tem como objetivo disponibilizar os papers, bem como os relatos de experiências educomunicativas apresentados durante o V ENCONTRO BRASILEIRO DE EDUCOMUNICAÇÃO, que teve como tema central: “Educação Midiática e Políticas Públicas”. O evento foi realizado em São Paulo, entre 19 e 21 de setembro de 2013, a partir de uma parceria entre o NCE/USP - Núcleo de Comunicação e Educação da USP, a Licenciatura em Educomunicação da ECA/USP, a ABPEducom – Associação Brasileira de Pesquisadores e Profissionais da Educomunicação e a FAPCOM – Faculdade Paulus de Tecnologia e Comunicação, que ofereceu seu campus, na Vila Mariana, para os atos do evento.
Os presentes anais disponibilizam o texto de abertura, de autoria do coordenador geral do evento, denominado “Educação midiática e políticas públicas: vertentes históricas da emergência da Educomunicação na América Latina”. Na sequência, apresentam 61 papers sobre aspectos específicos da temática geral, resultantes de pesquisas na área, seguidos de 27 relatos de práticas educomunicativas, em nível nacional
I Fórum CIDTFF: livro de posters
O CIDTFF [https://www.ua.pt/cidtff] é uma Unidade de Investigação da FCT criada em 1994 e localizada no
Departamento de Educação e Psicologia (DEP) da Universidade de Aveiro. Integra membros do DEP, de
outros departamento da Universidade e de outras Instituições de Ensino Superior.
O seu quadro epistemológico é definido na interação entre a formação de formadores e supervisão, em
conjunto com didáticas específicas (ciências, matemáticas, línguas, etc.) e Tecnologias da Informação e
Comunicação (TIC).
As áreas de investigação incluem processos de ensino/aprendizagem, as suas condições de regulação
(discursos institucionais), as circunstâncias em que tais processos ocorrem (atores, perfis, relações,
representações, recursos) e espaços de comunicação onde emergem (presencial, virtual, público, privado)
numa perspetiva de aprendizagem ao longo da vida, incluindo educação formal/tradicional, não-formal e
informal.
Os públicos-alvo do CIDTFF são escolas (diferentes níveis de educação, estudantes, professores e
educadores), outros educadores e stakeholders educacionais (por exemplo, decisores políticos, cuidadores,
municípios, bibliotecas).
O CIDTFF é a única Unidade de Investigação portuguesa com tal matriz, o que promove o seu prestígio
nacional e internacional.
O I Fórum do CIDTFF, cujos posters se encontram reunidos neste livro, tem como principais objetivos
divulgar internamente a investigação realizada no centro e criar oportunidades de partilha de ideias e troca
de conhecimento entre os seus investigadores.CIDTFF [https://www.ua.pt/cidtff] is an FCT Research Unit created in 1994 located at the Department of
Education and Psychology (DEP), University of Aveiro. It integrates members from the DEP, other UA
Departments and other Higher Education Institutions.
Its epistemological framework is defined on the interface between education of trainers and supervision,
together with Specific Didactics (Sciences, Maths, Languages, etc.) and ICT.
Research areas include processes of teaching/learning, their regulation conditions (institutional discourses),
the circumstances in which such processes occur (actors, profiles, relationships, representations, resources)
and communication spaces where they emerge (f2f, virtual, public, private) from a lifelong learning perspective,
including formal/traditional, non-formal and informal educational areas.
The targets of this R&D Centre are schools (different levels of education, students, teachers and trainers),
other educators and educational stakeholders (e.g. policy makers, caregivers, municipalities, libraries).
CIDTFF is the only Portuguese Research Unit with such a matrix, which promotes its national and
international prestige.
CIDTFF first forum, which posters are gathered on this book, has the main objectives of internally disseminating
the research conducted within the Research Unit and creating opportunities for sharing ideas and exchanging
knowledge among its researchers
Novo índice biológico para o diagnóstico da fibrose hepática na Esquistossomose mansoni
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Previous issue date: 2017Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, BrasilBackground – Periportal fibrosis is the major pathological consequence of the Schistosoma mansoni infection. Objective – To evaluate the
accuracy of serum markers and to construct an index to assess fibrosis. Methods – Patients (n=116) with schistosomiasis were evaluated by ultrasound
scan and measurements of serum levels of aminotransferases, γ-glutamyl transferase, alkaline phosphatase, hyaluronic acid, cytokines and platelets.
Ultrasound images were used to evaluate the fibrosis using Niamey’s classification and identified 19 patients without periportal fibrosis (patterns A
and B), 48 with mild to moderate fibrosis (C and D) and 49 with advanced fibrosis (E and F). Results – Using multivariate analysis, a model was
created, which involved alkaline phosphatase and platelets and could separate patients with different patterns of fibrosis. This index showed a better
performance in separating patients without fibrosis from with advanced periportal fibrosis. The biological index showed an area under the ROC
curve of 1.000. Using values below the lowest or above the highest cut-off point, the presence or absence of advanced fibrosis could be predicted
in all patients. Conclusion – The index constructed can be used to separate patients with different patterns of periportal fibrosis, specially to predict
advanced fibrosis in schistosomiasis patients