Use of record-linkage to handle non-response and improve alcohol consumption estimates in health survey data: a study protocol

<p>Introduction: Reliable estimates of health-related behaviours, such as levels of alcohol consumption in the population, are required to formulate and evaluate policies. National surveys provide such data; validity depends on generalisability, but this is threatened by declining response levels. Attempts to address bias arising from non-response are typically limited to survey weights based on sociodemographic characteristics, which do not capture differential health and related behaviours within categories. This project aims to explore and address non-response bias in health surveys with a focus on alcohol consumption.</p> <p>Methods and analysis: The Scottish Health Surveys (SHeS) aim to provide estimates representative of the Scottish population living in private households. Survey data of consenting participants (92% of the achieved sample) have been record-linked to routine hospital admission (Scottish Morbidity Records (SMR)) and mortality (from National Records of Scotland (NRS)) data for surveys conducted in 1995, 1998, 2003, 2008, 2009 and 2010 (total adult sample size around 40 000), with maximum follow-up of 16 years. Also available are census information and SMR/NRS data for the general population. Comparisons of alcohol-related mortality and hospital admission rates in the linked SHeS-SMR/NRS with those in the general population will be made. Survey data will be augmented by quantification of differences to refine alcohol consumption estimates through the application of multiple imputation or inverse probability weighting. The resulting corrected estimates of population alcohol consumption will enable superior policy evaluation. An advanced weighting procedure will be developed for wider use.</p> <p>Ethics and dissemination: Ethics approval for SHeS has been given by the National Health Service (NHS) Multi-Centre Research Ethics Committee and use of linked data has been approved by the Privacy Advisory Committee to the Board of NHS National Services Scotland and Registrar General. Funding has been granted by the MRC. The outputs will include four or five public health and statistical methodological international journal and conference papers.</p&gt

River Restoration Effects on Steelhead Populations in the Manistee River, Michigan: Analysis Using an Individual‐Based Model

The Manistee River, Michigan, watershed includes two dams as well as residential and agricultural development, and the river itself contains a sizeable population of steelhead Oncorhynchus mykiss that supports a valuable recreational fishery. Restoration of the Manistee River and its flow regime may improve steelhead habitat and the fishery. We developed an individual‐based model of steelhead in the Manistee River to assess the population effects of changes in the number of spawners, water discharge from Tippy Dam, and water temperature. The model follows steelhead from spring spawning to the end of the growing season in early fall and depicts the river environment as a series of cells that vary in dimension, water velocity, and substrate. Simulated water discharge, temperature, and prey availability changed daily based on observations from Tippy Dam. Empirically based models describe individual steelhead fry and parr foraging and growth. In the model, steelhead select habitats and maximize individual fitness while accounting for dominance and the availability of feeding territories. We calibrated the model to replicate fish growth, mortality, and population size. Simulation experiments manipulated the number of spawning females, water discharge, and water temperature. The results suggest that Manistee River steelhead incur density limitations in the fry and parr stages and that water discharge and temperature changes affect the number and biomass of parr. Increasing river discharge negatively affected parr numbers and weight. Decreasing maximum midsummer temperature increased parr numbers and weight when the change was large, but otherwise had little effect. These results indicate that restoration of the natural flow regime in the Manistee River will probably increase the quality of the habitat for steelhead but that density limitations in the fry and parr stages may ultimately limit population growth.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141355/1/tafs1654.pd

Reaching older people with PA delivered in football clubs: the reach, adoption and implementation characteristics of the Extra Time Programme.

Background Older adults (OA) represent a core priority group for physical activity and Public Health policy. As a result, significant interest is placed on how to optimise adherence to interventions promoting these approaches. Extra Time (ET) is an example of a national programme of physical activity interventions delivered in professional football clubs for OA aged 55+ years. This paper aims to examine the outcomes from ET, and unpick the processes by which these outcomes were achieved. Methods This paper represents a secondary analysis of data collected during the evaluation of ET. From the 985 OA reached by ET, n=486 adopted the programme and completed post-intervention surveys (typically 12 weeks). We also draw on interview data with 18 ET participants, and 7 staff who delivered the programme. Data were subject to thematic analysis to generate overarching and sub themes. Results Of the 486 participants, the majority 95%, (n= 462) were White British and 59.7% (n=290) were female. Most adopters (65.4%/n=318) had not participated in previous interventions in the host clubs. Social interaction was the most frequently reported benefit of participation (77.2%, n=375). While the reach of the club badge was important in letting people know about the programme, further work enhanced adoption and satisfaction. These factors included (i) listening to participants, (ii) delivering a flexible age-appropriate programme of diverse physical and social activities, (iii) offering activities which satisfy energy drives and needs for learning and (iv) extensive opportunities for social engagement. Conclusions Findings emerging from this study indicate that physical activity and health interventions delivered through professional football clubs can be effective for engaging OA

Treatment of Scarlatina.

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The Pandemic and its Impacts

The Pandemic has a long history, but the term of “pandemic” is still not been defined by many medical texts. There have been many significant pandemics recorded in human history, and the pandemic related crises have caused enormous negative impacts on health, economies, and even national security in the world. This article will explore the literature for the concept and history of pandemics; summarises the key features of a pandemics, and discusses the negative impacts on health, economy, social and global security of pandemics and disease outbreaks

No classical limit of quantum decay for broad states

Though the classical treatment of spontaneous decay leads to an exponential decay law, it is well known that this is an approximation of the quantum mechanical result which is a non-exponential at very small and large times for narrow states. The non exponential nature at large times is however hard to establish from experiments. A method to recover the time evolution of unstable states from a parametrization of the amplitude fitted to data is presented. We apply the method to a realistic example of a very broad state, the sigma meson and reveal that an exponential decay is not a valid approximation at any time for this state. This example derived from experiment, shows the unique nature of broad resonances

Lord Rutherford of Nelson, His 1908 Nobel Prize in Chemistry and Why He Didn't Get a Second Prize

"I have dealt with many different transformations with various periods of time, but the quickest that I have met was my own transformation in one moment from a physicist to a chemist." Ernest Rutherford (Nobel Banquet, 1908) This article is about how Ernest Rutherford (1871-1937) got the 1908 Nobel Prize in Chemistry and why he did not get a second Prize for his subsequent outstanding discoveries in physics, specially the discovery of the atomic nucleus and the proton. Who were those who nominated him and who did he nominate for the Nobel Prizes. In order to put the Prize issue into its proper context, I will briefly describe Rutherford's whereabouts. Rutherford, an exceptionally gifted scientist who revolutionized chemistry and physics, was moulded in the finest classical tradition. What were his opinions on some scientific issues such as Einstein's photon, uncertainty relations and the future prospects for atomic energy? What would he have said about the "Theory of Everything"?Comment: Extended version of an invited talk presented at the neutrino conference "Neutrino 2008", Christchurch, New Zealand, 25-31 May 200

The Impact of Border Carbon Adjustments under Alternative Producer Responses

Abstract and PDF report are also available on the MIT Joint Program on the Science and Policy of Global Change website (http://globalchange.mit.edu/)Border carbon adjustments (BCAs) have been proposed to address leakage and competitiveness concerns. In traditional assessments, firms regard BCAs as output taxes rather than implicit emissions taxes. Using a stylized energy-economic model, we analyze the impact of BCAs for alternative producer responses. When firms view BCAs as an implicit emissions tax, the outcome depends on whether or not firms can differentiate production across destination markets. If firms are able to produce a low-emissions variety for regions imposing BCAs, results are similar to when firms regard BCAs as an output tax. If firms produce a single variety for all markets, BCAs result in larger leakage reductions than in standard approaches. We also find that BCAs are less effective at addressing competitive concerns in scenarios that result in larger leakage reductions.This study received support from the MIT Joint Program on the Science and Policy of Global Change, which is funded by a consortium of government, industry and foundation sponsors

Speaker Sex Influences Processing of Grammatical Gender

A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author’s publication fees in this Open Access journal. The Open Access Fund, administered by librarians from the KU, KU Law, and KUMC libraries, is made possible by contributions from the offices of KU Provost, KU Vice Chancellor for Research & Graduate Studies, and KUMC Vice Chancellor for Research. For more information about the Open Access Fund, please see http://library.kumc.edu/authors-fund.xml.Spoken words carry linguistic and indexical information to listeners. Abstractionist models of spoken word recognition suggest that indexical information is stripped away in a process called normalization to allow processing of the linguistic message to proceed. In contrast, exemplar models of the lexicon suggest that indexical information is retained in memory, and influences the process of spoken word recognition. In the present study native Spanish listeners heard Spanish words that varied in grammatical gender (masculine, ending in -o, or feminine, ending in -a) produced by either a male or a female speaker. When asked to indicate the grammatical gender of the words, listeners were faster and more accurate when the sex of the speaker “matched” the grammatical gender than when the sex of the speaker and the grammatical gender “mismatched.” No such interference was observed when listeners heard the same stimuli, but identified whether the speaker was male or female. This finding suggests that indexical information, in this case the sex of the speaker, influences not just processes associated with word recognition, but also higher-level processes associated with grammatical processing. This result also raises questions regarding the widespread assumption about the cognitive independence and automatic nature of grammatical processes