Interview with Michael Kirby: Commonwealth Oral History Project

Interview with Michael Kirby carried out in Sydney on Friday, 28th March, 2014 as part of the Commonwealth Oral History Project. The project aims to produce a unique digital research resource on the oral history of the Commonwealth since 1965 through sixty oral history interviews with leading figures in the recent history of the organisation. It will provide an essential research tool for anyone investigating the history of the Commonwealth and will serve to promote interest in and understanding of the organisation. Biography: Kirby, Michael, 1939-. Deputy President of the Australian Conciliation & Arbitration Commission, 1974-1975; inaugural Chairman of the Australian Law Reform Commission, 1975-84. Judge of the Federal Court of Australia, 1983-1984; President of the New South Wales Court of Appeal, 1984-1996; Judge on the Court of Appeal of Solomon Islands, 1995-1996; Australian High Court Judge, 1996-2009; Commonwealth Eminent Persons' Group 2010-2011; UNDP Global Commission of HIV and the Law, 2010-2012; Commissioner of the UNAIDS Commission on Sustainable Health, 2013-2014; Head of the Commission of Inquiry on Alleged Human Rights Violations in the Democratic People's Republic of Korea, 2013-2014

Rapid and punctuated Late Holocene recession of Siling Co, central Tibet

This work was supported by a National Science Foundation grant from the Tectonics program (EAR-0911587) to E.K. and K.P.F. Additional support to E.W. was provided by grants from the Chinese Academy of Sciences (XDB03010500). X.S. also thanks the support from the Earth Observatory of Singapore, Nanyang Technological University through its funding from the National Research Foundation Singapore and the Singapore Ministry of Education under the Research Centers of Excellence initiative.Variations in the strength of the Asian monsoon during Holocene time are thought to have been associated with widespread changes in precipitation across much of Tibet. Local records of monsoon strength from cave deposits, ice cores, and lake sediments typically rely on proxy data that relate isotopic variations to changes in precipitation. Lake expansion and contraction in response to changing water balance are likewise inferred from sedimentologic, isotopic and paleobiologic proxies, but relatively few direct records of changes in lake volume from preserved shorelines exist. Here we utilize relict shoreline deposits and associated alluvial fan features around Siling Co, the largest lake in central Tibet, to reconstruct centennial-to-millennial-scale variations in lake area and volume over the Holocene. Mapping and surveying of lacustrine shorelines coupled with optically stimulated luminescence dating of associated deposits indicate protracted occupation of a highstand elevation from >8 ka to 4 ka, followed by rapid recession that was likely punctuated by several stillstands of centennial-scale duration. Calculation of the changes in lake surface area and past hydrologic indices of the Siling Co basin suggests the effective moisture during the early Holocene highstand was approximately three times greater than today. In contrast to other lakes in central and western Tibet, our results suggest that Siling Co did not begin to recede synchronously with decreasing solar insolation at ca. 9–8 ka. Rather, initial recession of Siling Co appears to correspond to a time period of enhanced aridity and weakened monsoon in both Africa and Asia at ca. 4.2 ka. Our results add to a growing body of literature that suggest a period of relatively severe aridity on the Tibetan Plateau at this time. We suggest that subsequent punctuated recession of Siling Co was punctuated by similar periods of abrupt climate change during the Late Holocene.Publisher PDFPeer reviewe

A Learning Community for New Chairs

Key elements of an effective professional learning community will be discussed, including readings, peer mentoring, meeting structure, composition, and timing of topics. Presenters will discuss the challenges of their first years as chairs, particularly finding their individual leadership styles and a balance between professional and personal lives

Field Pea Variety Trial Archive

This report features the available pea data from 2003-2017. Crop performance testing results are released annually through the activities of SDSU Extension and the South Dakota Agricultural Experiment Station at SDSU

A tailored compassion-focused therapy program for sexual minority young adults with depressive symotomatology: study protocol for a randomized controlled trial.

Background: Lesbian, gay, and bisexual (LGB) men and women represent one of the highest-risk populations for depressive symptomatology and disorders, with young LGB adults being at greatest risk. To date, there have been no randomized controlled trials (RCT) to specifically target depressive symptoms in young LGB adults. This is despite research highlighting unique predictors of depressive symptomatology in this population. Here we outline a protocol for an RCT that will test the preliminary efficacy of a tailored compassion-focused therapy (CFT) intervention for young LGB adults compared with a self-directed cognitive behavioral therapy (CBT) program with no specific tailoring for LGB individuals.N/

Crustal strength in central Tibet determined from Holocene shoreline deflection around Siling Co

Controversial end member models for the growth and evolution of the Tibetan Plateau demand quantitative constraints of the lithospheric rheology. Direct determinations of bulk crustal rheology, however, remain relatively sparse. Here we use the flexural rebound of lacustrine shorelines developed during the Lingtong highstand around Siling Co, in central Tibet, to place bounds on the effective elastic thickness (T[subscript e]) and viscosity of Tibetan crust. Shoreline features associated with the Lingtong highstand complex ∼60 meters above present lake level are deflected from horizontal by 2–4 meters over wavelengths of ∼200 kilometers. Optically stimulated luminescence dating of aggradational shoreline deposits indicate that these lake levels were reached at 6–4 ka. Assuming that surface loads were entirely supported by an elastic layer overlying an inviscid fluid, the range and spatial distribution of variations in shoreline elevation are consistent with deflections predicted by a uniform elastic plate with thickness, T[subscript e] of 20–30 km. If viscoelastic relaxation in response to lake withdrawal is complete, our data suggest an average viscosity ≤10¹⁹ Pa s. These results imply that the apparent viscosity of the lower crust inferred over millennial timescales is comparable with that estimated from post-seismic relaxation over decadal timescale.This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier and can be found at: http://www.journals.elsevier.com/earth-and-planetary-science-letters/,The author has provided the additional file, "Reply to Comment on “Crustal strength in central Tibet determined from Holocene shoreline deflection around Siling Co.” The published versions of the "Reply to Comment ..." and the "Comment on ... " to which the reply refers are available on the publisher's journal site as listed above.Keywords: Tibetan Plateau, Effective elastic thickness, Lake shoreline, Crustal strength, Viscosit

The Lantern Vol. 12, No. 2, March 1944

• Save in His Own Country • Philosopher and Soldier • Soap Bubbles • Who is my Brother? • A Real Sea-Captain • Quatrain on Solitude • Wind Ahead • Jewel Song • The Sail, a Translation • They Also Serve • Ever the Twain • After the Rain • The Low-Down on Electronics • Sing, My Heart • Interlude • Unconquerable Soul • The Covenant • The Lost Warriors • Fragment • Arrivalhttps://digitalcommons.ursinus.edu/lantern/1032/thumbnail.jp

Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study.

Variation in response to biologic therapy for inflammatory diseases, such as psoriasis, is partly driven by variation in drug exposure. Real-world psoriasis data were used to develop a pharmacokinetic/pharmacodynamic (PK/PD) model for the first-line therapeutic antibody ustekinumab. The impact of differing dosing strategies on response was explored. Data were collected from a UK prospective multicenter observational cohort (491 patients on ustekinumab monotherapy, drug levels, and anti-drug antibody measurements on 797 serum samples, 1,590 measurements of Psoriasis Area Severity Index (PASI)). Ustekinumab PKs were described with a linear one-compartment model. A maximum effect (Emax ) model inhibited progression of psoriatic skin lesions in the turnover PD mechanism describing PASI evolution while on treatment. A mixture model on half-maximal effective concentration identified a potential nonresponder group, with simulations suggesting that, in future, the model could be incorporated into a Bayesian therapeutic drug monitoring "dashboard" to individualize dosing and improve treatment outcomes