1,420 research outputs found
Anthropometric changes and fluid shifts
Several observations of body size, shape, posture, and configuration were made to document changes resulting from direct effects of weightlessness during the Skylab 4 mission. After the crewmen were placed in orbit, a number of anatomical and anthropometric changes occurred including a straightening of the thoracolumbar spine, a general decrease in truncal girth, and an increase in height. By the time of the earliest in-flight measurement on mission day 3, all crewmen had lost more than two liters of extravascular fluid from the calf and thigh. The puffy facies, the bird legs effect, the engorgement of upper body veins, and the reduced volume of lower body veins were all documented with photographs. Center-of-mass measurements confirmed a fluid shift cephalad. This shift remained throughout the mission until recovery, when a sharp reversal occurred; a major portion of the reversal was completed in a few hours. The anatomical changes are of considerable scientific interest and of import to the human factors design engineer, but the shifts of blood and extravascular fluid are of more consequence. It is hypothesized that the driving force for the fluid shift is the intrinsic and unopposed lower limb elasticity that forces venous blood and then other fluid cephalad
Skylab medical data evaluation program (SMEDEP)
A day-by-day summary of selected data collected during the experiment is presented. The clinical and environmental data are presented in a mission-day format along with a tabulation of biomedical measurements whose values exceed three standard deviations from the preflight measurements
Automated detection of time-dependent cross-correlation clusters in nonstationary time series
A novel method for the detection of cross-correlation clusters in multivariate time series is suggested. It is based on linear combinations of the eigenvectors corresponding to the largest eigenvalues of the equal-time cross-correlation matrix. The linear combinations are found in a systematic way by maximizing an appropriate distance measure. The performance of the algorithm is evaluated with a flexible time-seriesbased test framework for cluster algorithms. Attribution errors are investigated quantitatively in model data and a comparison with three alternative approaches is made. As the algorithm is suitable for unsupervised online application we demonstrate its time-resolved use in the example of cluster detection in time series from human electroencephalogram
Standard Glass Container Association cost system
Your Committee has viewed the subject in the light that it is desirable and essential that each manufacturer of glass containers should know his own costs and that his costs actually include all proper elements of cost, and that these elements be properly allocated. That it is further desirable and essential that each manufacturer of glass containers should, as far as it is possible, know that all other manufacturers of glass containers are running their respective businesses with proper knowledge of their costs. It has not been the intention of your Committe to lay down any hard and fast rule, but rather to set out a general plan which could be generally adopted by all the members of the Glass Container Association with perfect propriety, but perhaps with certain necessary and relatively immaterial modifications in individual instances
Design, Tests, and Repair Procedures for the Electrical Insulation of the Superconducting W7-X Magnets
HDLs protect the MIN6 insulinoma cell line against tunicamycin-induced apoptosis without inhibiting ER stress and without restoring ER functionality.
HDLs protect pancreatic beta cells against apoptosis induced by several endoplasmic reticulum (ER) stressors, including thapsigargin, cyclopiazonic acid, palmitate and insulin over-expression. This protection is mediated by the capacity of HDLs to maintain proper ER morphology and ER functions such as protein folding and trafficking. Here, we identified a distinct mode of protection exerted by HDLs in beta cells challenged with tunicamycin (TM), a protein glycosylation inhibitor inducing ER stress. HDLs were found to inhibit apoptosis induced by TM in the MIN6 insulinoma cell line and this correlated with the maintenance of a normal ER morphology. Surprisingly however, this protective response was neither associated with a significant ER stress reduction, nor with restoration of protein folding and trafficking in the ER. These data indicate that HDLs can use at least two mechanisms to protect beta cells against ER stressors. One that relies on the maintenance of ER function and one that operates independently of ER function modulation. The capacity of HDLs to activate several anti-apoptotic pathways in beta cells may explain their ability to efficiently protect these cells against a variety of insults
Chemical Vapor Deposition Model of Polysilicon in a Trichlorosilane and Hydrogen System
The traditional polysilicon processes should be refined when addressing the low energy consumption requirement for the production of solar grade silicon. This paper addresses the fluid dynamic conditions required to deposit polysilicon in the traditional Siemens reactor. Analytical solutions for the deposition process are presented, providing information on maximizing the rate between the amount of polysilicon obtained and the energy consumed during the deposition process. The growth rate, deposition efficiency, and power-loss dependence on the gas velocity, the mixture of gas composition, the reactor pressure, and the surface temperature have been analyzed. The analytical solutions have been compared to experimental data and computational solutions presented in the literature. At atmospheric pressure, the molar fraction of hydrogen at the inlet should be adjusted to the range of 0.85–0.90, the gas inlet temperature should be raised within the interval of 673 and 773 K, and the gas velocity should reach the Reynolds number 800. The resultant growth rate will be between 6 and 6.5 _m min−1. Operation above atmospheric pressure is strongly recommended to achieve growth rates of 20 _m min−1 at 6 atm
Guide for Controlling Cotton Insects in the High Plains, Rolling Plains and Trans-Pecos Areas of Texas.
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