Observation of a tricritical wedge filling transition in the 3D Ising model

In this Letter we present evidences of the occurrence of a tricritical filling transition for an Ising model in a linear wedge. We perform Monte Carlo simulations in a double wedge where antisymmetric fields act at the top and bottom wedges, decorated with specific field acting only along the wegde axes. A finite-size scaling analysis of these simulations shows a novel critical phenomenon, which is distinct from the critical filling. We adapt to tricritical filling the phenomenological theory which successfully was applied to the finite-size analysis of the critical filling in this geometry, observing good agreement between the simulations and the theoretical predictions for tricritical filling.Comment: 5 pages, 3 figure

Aggregate and Welfare Effects of Redistribution of Wealth Under Inflation and Price-Level Targeting

Since the work of Doepke and Schneider (2006a) and Meh and Terajima (2008), we know that inflation causes major redistribution of wealth - between households and the government, between nationals and foreigners, and between households within the same country. Two types of monetary policy, inflation targeting (IT) and price level targeting (PT), have very different implications for the price level path subsequent to a price-level shock, and consequently, have different redistributional properties which is what we explore in this paper. For Canada, we show that the magnitude of redistributions of an unexpected 1% price-level increase under IT is about three times larger than under PT. Households' and foreigners' wealth losses from a price level increase is matched by the gains of the government. Even though this redistribution is zero-sum, we observe positive effects on GDP due to the wealth loss, the lower value of the debt and its associated fiscal adjustment, and the non-linear effects on work effort of the redistribution of wealth across households. Finally, the direction of the change in the weighted welfare of households depends on the fiscal policy.Economic models; Monetary policy framework; Sectoral balance sheet; Inflation: costs and benefits; Inflation targets; Inflation and prices

Phenological and molecular studies on the introduced seaweed Dictyota cyanoloma (Dictyotales, Phaeophyceae) along the Mediterranean coast of the Iberian Peninsula

Dictyota cyanoloma, a distinctive brown algal species characterized by a blue-iridescent margin, was recently reported as an introduced species in the Mediterranean Sea but little is known about its distribution dynamics, morphological plasticity and genetic structure. In this integrative study, we evaluate its past and present occurrence along the Mediterranean Iberian coast, assess the species' phenology in Palamos (Girona, Spain) and analyze the haplotype diversity by sequencing 49 individuals from nine sampling sites for different chloroplast and mitochondrial DNA regions. Although D. cyanoloma currently occurs along all the Mediterranean Iberian coasts (in 19 of 36 localities sampled, mostly in marinas and harbour environments), we were not able to find any herbarium material of this species (at BCN-Phyc and MA) predating the year 1987. In Palamos, D. cyanoloma is present all through the year, with a maximum development in winter and a minimum in summer. Fertile specimens are absent during summer (July and August). Sporophytes are dominant from January to June and gametophytes were found only in February, March and June. Information about the antheridia, which has never been described before, is provided. Two chloroplast and three mitochondrial haplotypes were observed, indicating that multiple introductions of D. cyanoloma occurred in the study area. Additionally, the genetic structure suggests that spread did not occur through simple advancing wave fronts but by several longdistance dispersal events. Further studies employing microsatellite markers could potentially offer a better resolution to unravel expansion and colonisation dynamics of D. cyanoloma in the Mediterranean Sea

Closed-loop phase equilibria of a symmetrical associating mixture of square-well molecules examined by Gibbs ensemble Monte Carlo simulation

A closed loop of liquid-liquid immiscibility for a simple model binary symmetrical mixture of square-well monomers with a single short-ranged interaction site has been recently observed using the Gibbs ensemble Monte Carlo technique @L. A. Davies, G. Jackson, and L. F. Rull, Phys. Rev. Lett. 82, 5285 ~1999!#. This model system has unfavorable mean-field interactions between unlike components which leads to phase separation at intermediate temperatures; the addition of a directional bonding site leads to association and miscibilty of the system at low temperatures. In this work we present a detailed study of the effect of a variation in pressure and of the strength of the bonding interaction on the phase equilibria of such a model system by Gibbs ensemble simulation. The phase diagram is dominated by regions of liquid-liquid immiscibility which are bounded at high temperatures by an upper critical solution temperature and by a lower critical solution temperature ~LCST! for specific values of the pressure and association strength. This closed-loop region is seen to increase in size as the pressure of the system is increased. For weak bonding interaction strengths the system does not possess a LCST and is seen to exhibit regions of two-phase vapor-liquid coexistence which are separated from the region of liquid-liquid immiscibility by a three-phase line. The phase equilibria of the same model system is also determined using the statistical associating fluid theory as adapted for potentials of variable range; the theory provides a good description of the closed-loop immiscibility and other features of the phase diagram

Engineering physiological environments to advance kidney organoid models from human pluripotent stem cells

During embryogenesis, the mammalian kidney arises because of reciprocal interactions between the ureteric bud (UB) and the metanephric mesenchyme (MM), driving UB branching and nephron induction. These morphogenetic processes involve a series of cellular rearrangements that are tightly controlled by gene regulatory networks and signaling cascades. Here, we discuss how kidney developmental studies have informed the definition of procedures to obtain kidney organoids from human pluripotent stem cells (hPSCs). Moreover, bioengineering techniques have emerged as potential solutions to externally impose controlled microenvironments for organoid generation from hPSCs. Next, we summarize some of these advances with major focus On recent works merging hPSC-derived kidney organoids (hPSC-kidney organoids) with organ-on-chip to develop robust models for drug discovery and disease modeling applications. We foresee that, in the near future, coupling of different organoid models through bioengineering approaches will help advancing to recreate organ-to-organ crosstalk to increase our understanding on kidney disease progression in the human context and search for new therapeutics

Observation of a tricritical wedge filling transition in the 3D Ising model

In this letter we present evidences of the occurrence of a tricritical filling transition for an Ising model in a linear wedge. We perform Monte Carlo simulations in a double wedge where antisymmetric fields act at the top and bottom wedges, decorated with specific field act- ing only along the wegde axes. A finite-size scaling analysis of these simulations shows a novel critical phenomenon, which is distinct from the critical filling. We adapt to tricritical filling the phenomenological theory which successfully was applied to the finite-size analysis of the critical filling in this geometry, observing good agreement between the simulations and the theoretical predictions for tricritical filling

La Termogènesi als calorímetres per conducció: característiques dinàmiques i possibilitats deconvolutives

Es descriuen les característiques generals dels dispositius calorimètrics, les possibilitats de tractament mitjançant models i els mètodes per aproximar-se a la termogènesi o dissipació instantània al si de la cèl•lula laboratori. La descripció dinàmica es fa dins de l'espai freqüencial, que permet introduir de manera natural diferents límits de freqüència segons les característiques dels dispositius i del procés que vol estudiar-se. Per al tractament global dels calorímetres s'utilitza una escala relativa de temps i de freqüència. Això permet tractar sistemàticament les condicions imposades per les tècniques deconvolutives, l'aparellatge experimental i els propis fenòmens físics.General features of flow or conduction calorimeters are briefly described together with several methods to obtain the thermogenesis or instantaneous power dissipated inside the laboratory cell. The possibi l ities of solvable models are also discussed. The dynamic behaviour of the calorimeter is readily described in frequency space, thus allowing the intrcduction of several frequential limits depending on the characteristics both of the device and of the phenomenon under study. A systematic treatment of conduction calorimeters may be attained if relative scales, i n time (t/τ1) and frequency (θ τ1), are considered. Now, the efficiency of a given deconvolutive technique and the limits imposed by the experimental device itself or by the physical phenomena studied are easily evaluated

Computer simulations of nematic drops: Coupling between drop shape and nematic order

We perform Monte Carlo computer simulations of nematic drops in equilibrium with their vapor using a Gay-Berne interaction between the rod-like molecules. To generate the drops, we initially perform NPT simulations close to the nematic-vapor coexistence region, allow the system to equilibrate and subsequently induce a sudden volume expansion, followed with NVT simulations. The resultant drops coexist with their vapor and are generally not spherical but elongated, have the rodlike particles tangentially aligned at the surface and an overall nematic orientation along the main axis of the drop. We find that the drop eccentricity increases with increasing molecular elongation, κ. For small κ the nematic texture in the drop is bipolar with two surface defects, or boojums, maximizing their distance along this same axis. For sufficiently high κ, the shape of the drop becomes singular in the vicinity of the defects, and there is a crossover to an almost homogeneous texture; this reflects a transition from a spheroidal to a spindle-like dro

Phase equilibria and critical behavior of square‐well fluids of variable width by Gibbs ensemble Monte Carlo simulation

The vapor–liquid phase equilibria of square†well systems with hard†sphere diameters σ, well†depths ε, and ranges λ=1.25, 1.375, 1.5, 1.75, and 2 are determined by Monte Carlo simulation. The two bulk phases in coexistence are simulated simultaneously using the Gibbs ensemble technique. Vapor–liquid coexistence curves are obtained for a series of reduced temperatures between about Tr=T/Tc=0.8 and 1, where Tc is the critical temperature. The radial pair distribution functions g(r) of the two phases are calculated during the simulation, and the results extrapolated to give the appropriate contact values g(σ), g(λσ−), and g(λσ+). These are used to calculate the vapor†pressure curves of each system and to test for equality of pressure in the coexisting vapor and liquid phases. The critical points of the square†well fluids are determined by analyzing the density†temperature coexistence data using the first term of a Wegner expansion. The dependence of the reduced critical temperature T* c=kTc/ε, pressure P* c=Pcσ3/ε, number density Ï * c=Ï cσ3, and compressibility factor Z=P/(Ï kT), on the potential range λ, is established. These results are compared with existing data obtained from perturbation theories. The shapes of the coexistence curves and the approach to criticality are described in terms of an apparent critical exponent β. The curves for the square†well systems with λ=1.25, 1.375, 1.5, and 1.75 are very nearly cubic in shape corresponding to near†universal values of β (β≊0.325). This is not the case for the system with a longer potential range; when λ=2, the coexistence curve is closer to quadratic in shape with a near†classical value of β (β≊0.5). These results seem to confirm the view that the departure of β from a mean†field or classical value for temperatures well below critical is unrelated to long†range, near†critical fluctuations

Sex-specific phenotypic integration: Endocrine profiles, coloration, and behavior in fledgling boobies

The intensity of color expression in animals plays a key role in social environments as a mechanism to signal individual capacities in competitive contests. Selective pressures for resource competition differ at different stages of life and between sexes; therefore, coloration is expected to vary between juveniles and adults and between males and females. Exploring the covariance between coloration and other traits may help to understand the functional significance of color and the action of natural selection on multivariate phenotypes. Melanin-based plumage coloration was investigated in the masked booby Sula dactylatra in relation to melanin concentration, sex, hormone levels, and shy-bold behavior of chicks close to fledging. Darker brown boobies showed higher levels of both eumelanin and pheomelanin concentration and lower body mass. Males behaved bolder than females and showed on average 8% larger brown patches. Bolder females had smaller brown patches. Bolder individuals also had lower levels of circulating testosterone, but no differences in corticosterone levels were found. Stronger phenotypic integration was observed in females than males. Our study suggests that juvenile melanic coloration may reflect behavioral strategies by sex, endocrine profiles, and body mass indicating the convergence of different adaptive functions in a given phenotype, this being more evident in females. Direction of correlations differed from those predicted under the pleiotropic idea for color-related traits. These results suggest the possibility that juvenile plumage acts as a signaling system in a social context within the age class and suggest that plumage coloration may indicate different behavioral strategies. © The Author 2013.The study was supported by Spanish Ministerio de Ciencia e Innovación (CGL2009-10883-C02-01; CGL2012-40229-C02-02).Peer Reviewe