The Influence of The Use of Digital Comics Vs E-Books and Learning Motivation on The Learning Outcomes of History of Class XI Social Studies Students of SMA Negeri 2 and 4 Probolinggo

The quality of learning is largely determined by teachers. They are required to be skilled in bringing and guiding their students so that they can learn optimally. The objectives of this study are: (1) To find out how much influence the use of digital comics vs. e-books has on the learning outcomes of class XI social studies students at SMA Negeri 2 and SMA Negeri 4 Probolinggo. (2) To find out how much influence of the use of digital comics vs e-books and high and low student motivation is on the learning outcomes of class XI social studies students at SMA Negeri 2 and SMA Negeri 4 Probolinggo. (3) To find out whether or not there is interaction in the use of digital comic media vs e-books and learning motivation towards the learning outcomes of class XI social studies students at SMA Negeri 2 and SMA Negeri 4 Probolinggo. The data collection technique is learning outcomes using tests and for motivation using questionnaires, and data analysis using 2-pathway variance analysis (Anava). The conclusions of this study are: 1) There is an influence on the use of digital comics vs e-books on learning outcomes 2) There is an influence on the use of digital comics vs e-books and high and low student motivation on learning outcomes. 3) There is an interaction in the use of digital comic media vs e-books and learning motivation towards learning outcomes. In learning activities in the 21st century era, teachers are advised to provide and use digital media such as digital comics, so that students are interested in learning. Thus, students can be active and understand the material taught by the teacher and can improve their learning achievement.Kualitas pembelajaran sangat ditentukan oleh guru, guru dituntut untuk terampil dalam membawa dan membimbing siswanya agar mereka bisa belajar secara optimal. Tujuan dari penelitian ini adalah: (1) Untuk mengetahui seberapa besar pengaruh penggunaan komik digital vs e-book terhadap hasil belajar siswa kelas XI IPS di SMA Negeri 2 dan SMAN 4 Probolinggo. (2) Untuk mengetahui seberapa besar pengaruh motivasi siswa terhadap hasil belajar siswa kelas XI IPS di SMAN 2 dan SMA Negeri 4 Probolinggo. (3) Untuk mengetahui pengaruh interaksi penggunaan media komik digital vs e-book dan motivasi belajar terhadap hasil belajar siswa kelas XI IPS di SMAN 2 dan 4 Probolinggo. Adapun kesimpulan hasil penelitian ini adalah: (1) Ada perbedaan hasil belajar sejarah antara kelompok siswa yang mengikuti pembelajaran dengan menggunakan komik digital dan kelompok siswa yang mengikuti pembelajaran dengan menggunakan e-book. (2) Ada perbedaan hasil belajar sejarah antara kelompok siswa yang mengikuti pembelajaran menggunakan komik digital dan e-book dengan motivasi belajar siswa. Dengan demikian penggunaan komik digital dan e-book berpengaruh pada hasil belajar sejarah. (3) Ada interaksi antara kelompok siswa yang mengikuti pembelajaran dengan menggunakan komik digital dan kelompok siswa yang mengikuti pembelajaran dengan menggunakan e-book dengan motivasi belajar siswa. Siswa yang memiliki motivasi tinggi nilai belajarnya tinggi sedang yang memiliki motivasi rendah hasil belajarnya rendah. Dalam kegiatan pembelajaran di era abad 21 guru disarankan menyediakan dan menggunakan media digital seperti komik gital ini, agar siswa tertarik dalam pembelajaran. Dengan demikian siswa bisa aktif dan memahami materi yang diajarkan oleh guru dan dapat meningkatkan prestasi belajarnya

Is there an optimal strategy for real-time continuous glucose monitoring in pediatrics? A 12-month French multi-center, prospective, controlled randomized trial (Start-In!)

AIM: To compare the efficacy of three strategies for real-time continuous glucose monitoring (RT-CGM) over 12 months in children and adolescents with type 1 diabetes. METHODS: A French multicenter trial (NCT00949221) with a randomized, controlled, prospective, open, and parallel-group design was conducted. After 3 months of RT-CGM, patients were allocated to one of three groups: return to self-monitoring of blood glucose, continuous CGM (80% of the time), or discontinuous CGM (40% of the time). The primary outcome was hemoglobin A1c (HbA1c) levels from 3 to 12 months. The secondary outcomes were acute metabolic events, hypoglycemia, satisfaction with CGM and cost. RESULTS: We included 151 subjects, aged 2 to 17 years, with a mean HbA1c level of 8.5% (SD0.7; 69 mmol/mol). The longitudinal change in HbA1c levels was similar in all three groups, at 3, 6, 9 and 12 months. The medical secondary endpoints did not differ between groups. The rate of severe hypoglycemia was significantly lower than that for the pretreatment year for the entire study population. Subjects reported consistent use and good tolerance of the device, regardless of age or insulin treatment. The use of full-time RT-CGM for 3 months costs the national medical insurance system €2629 per patient. CONCLUSION: None of the three long-term RT-CGM strategies evaluated in pediatric type 1 diabetes was superior to the others in terms of HbA1c levels. CGM-use for 3 months decreased rates of severe hypoglycemia. Our results confirm the feasibility of long-term RT-CGM-use and the need to improve educational support for patients and caregivers

Establishing glycaemic control with continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes: experience of the PedPump Study in 17 countries

AIMS/HYPOTHESIS: To assess the use of paediatric continuous subcutaneous infusion (CSII) under real-life conditions by analysing data recorded for up to 90 days and relating them to outcome. METHODS: Pump programming data from patients aged 0-18 years treated with CSII in 30 centres from 16 European countries and Israel were recorded during routine clinical visits. HbA(1c) was measured centrally. RESULTS: A total of 1,041 patients (age: 11.8 +/- 4.2 years; diabetes duration: 6.0 +/- 3.6 years; average CSII duration: 2.0 +/- 1.3 years; HbA(1c): 8.0 +/- 1.3% [means +/- SD]) participated. Glycaemic control was better in preschool (n = 142; 7.5 +/- 0.9%) and pre-adolescent (6-11 years, n = 321; 7.7 +/- 1.0%) children than in adolescent patients (12-18 years, n = 578; 8.3 +/- 1.4%). There was a significant negative correlation between HbA(1c) and daily bolus number, but not between HbA(1c) and total daily insulin dose. The use of 7.5%. The incidence of severe hypoglycaemia and ketoacidosis was 6.63 and 6.26 events per 100 patient-years, respectively. CONCLUSIONS/INTERPRETATION: This large paediatric survey of CSII shows that glycaemic targets can be frequently achieved, particularly in young children, and the incidence of acute complications is low. Adequate substitution of basal and prandial insulin is associated with a better HbA(1c)

The mediating role of shared flow and perceived emotional synchrony on compassion for others in a mindful-dancing program

While there is a growing understanding of the relationship between mindfulness and compassion, this largely relates to the form of mindfulness employed in first-generation mindfulness-based interventions such as Mindfulness-Based Stress Reduction. Consequently, there is limited knowledge of the relationship between mindfulness and compassion in respect of the type of mindfulness employed in second-generation mindfulness-based interventions (SG-MBIs), including those that employ the principle of working harmoniously as a “secular sangha.” Understanding this relationship is important because research indicates that perceived emotional synchrony (PES) and shared flow—that often arise during participation in harmonized group contemplative activities—can enhance outcomes relating to compassion, subjective well-being, and group identity fusion. This pilot study analyzed the effects of participation in a mindful-dancing SG-MBI on compassion and investigated the mediating role of shared flow and PES. A total of 130 participants were enrolled into the study that followed a quasi-experimental design with an intervention and control group. Results confirmed the salutary effect of participating in a collective mindful-dancing program, and demonstrated that shared flow and PES fully meditated the effects of collective mindfulness on the kindness and common humanity dimensions of compassion. Further research is warranted to explore whether collective mindfulness approaches, such as mindful dancing, may be a means of enhancing compassion and subjective well-being outcomes due to the mediating role of PES and shared flow.N/

Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers

Modern humans have populated Europe for more than 45,000 years1,2. Our knowledge of the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to the scarceness and poor molecular preservation of human remains from that period3. Here we analyse 356 ancient hunter-gatherer genomes, including new genomic data for 116 individuals from 14 countries in western and central Eurasia, spanning between 35,000 and 5,000 years ago. We identify a genetic ancestry profile in individuals associated with Upper Palaeolithic Gravettian assemblages from western Europe that is distinct from contemporaneous groups related to this archaeological culture in central and southern Europe4, but resembles that of preceding individuals associated with the Aurignacian culture. This ancestry profile survived during the Last Glacial Maximum (25,000 to 19,000 years ago) in human populations from southwestern Europe associated with the Solutrean culture, and with the following Magdalenian culture that re-expanded northeastward after the Last Glacial Maximum. Conversely, we reveal a genetic turnover in southern Europe suggesting a local replacement of human groups around the time of the Last Glacial Maximum, accompanied by a north-to-south dispersal of populations associated with the Epigravettian culture. From at least 14,000 years ago, an ancestry related to this culture spread from the south across the rest of Europe, largely replacing the Magdalenian-associated gene pool. After a period of limited admixture that spanned the beginning of the Mesolithic, we find genetic interactions between western and eastern European hunter-gatherers, who were also characterized by marked differences in phenotypically relevant variants

Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers

Modern humans have populated Europe for more than 45,000 years(1,2). Our knowledge of the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to the scarceness and poor molecular preservation of human remains from that period(3). Here we analyse 356 ancient hunter-gatherer genomes, including new genomic data for 116 individuals from 14 countries in western and central Eurasia, spanning between 35,000 and 5,000 years ago. We identify a genetic ancestry profile in individuals associated with Upper Palaeolithic Gravettian assemblages from western Europe that is distinct from contemporaneous groups related to this archaeological culture in central and southern Europe(4), but resembles that of preceding individuals associated with the Aurignacian culture. This ancestry profile survived during the Last Glacial Maximum (25,000 to 19,000 years ago) in human populations from southwestern Europe associated with the Solutrean culture, and with the following Magdalenian culture that re-expanded northeastward after the Last Glacial Maximum. Conversely, we reveal a genetic turnover in southern Europe suggesting a local replacement of human groups around the time of the Last Glacial Maximum, accompanied by a north-to-south dispersal of populations associated with the Epigravettian culture. From at least 14,000 years ago, an ancestry related to this culture spread from the south across the rest of Europe, largely replacing the Magdalenian-associated gene pool. After a period of limited admixture that spanned the beginning of the Mesolithic, we find genetic interactions between western and eastern European hunter-gatherers, who were also characterized by marked differences in phenotypically relevant variants.Molecular Technology and Informatics for Personalised Medicine and Healt

Kemandirian Belajar dan Resiliensi Mahasiswa Tingkat Awal Pendidikan Matematika Selama Masa Pandemi COVID-19

Kemandirian belajar dan resiliensi merupakan aspek pendorong mahasiswa dalam melakukan pembelajaran daring seperti saat ini.  Penelitian ini dilakukan karena peneliti ingin menggambarkan bagaimana kemandirian belajar dan resiliensi mahasiswa pendidikan matematika tingkat awal Universitas Muhammadiyah Prof. Dr. Hamka selama pembelajaran daring. Penelitian ini bertujuan untuk memberikan gambaran atau informaasi mengenai tingkat kemandirian belajar dan resiliensi mahasiswa pendidikan matematika tingkat awal di Universitas Muhammadiyah Prof. Dr. Hamka. Riset yang dilakukan memakai pendekatan deskriptif kuantitatif. Instrumen yang digunakan berupa angket tertutup. Jumlah sampel dalam riset ini merupakan 61 mahasiswa semester 2 dari pendidikan Matematika. Hasil penelitian menunjukan bahwa 22,95% dari seluruh sampel mahasiswa mempunyai tingkat kemandirian belajar yang sangat tinggi, 52,46% mempunyai tingkat kemandirian yang baik serta 24,59% mahasiswa memiliki tingkat kemandirian yang cukup baik. Selanjutnya didapatkan bahwa 9,84% mahasiswa memiliki tingkat resiliensi yang sangat baik, 70,49% memiliki tingkat resiliensi yang baik dan 19,60% mahasiswa memiliki tingkat resiliensi yang cukup baik. Kesimpulan dari penelitian ini menunjukan bahwa tingkat kemandirian belajar dan resiliensi mahasiswa tingkat awal pendidikan matematika Universitas Muhammadiyah Prof. Dr. Hamka sudah baik dengan masing – masing rata – rata adalah 79,82 dan 73,67