Voyager Interstellar Mission (VIM)

The DSN (Deep Space Network) mission support requirements for the Voyager Interstellar Mission (VIM) are summarized. The general objectives of the VIM are to investigate the interplanetary and interstellar media and to continue the Voyager program of ultraviolet astronomy. The VIM will utilize both Voyager spacecraft for the period from January 1990 through December 2019. The mission objectives are outlined and the DSN support requirements are defined through the presentation of tables and narratives describing the spacecraft flight profile; DSN support coverage; frequency assignments; support parameters for telemetry, control and support systems; and tracking support responsibility

Topographic Map Acquisition In U.S. Academic Libraries

published or submitted for publicatio

First-principles calculation of mechanical properties of Si <001> nanowires and comparison to nanomechanical theory

We report the results of first-principles density functional theory calculations of the Young's modulus and other mechanical properties of hydrogen-passivated Si nanowires. The nanowires are taken to have predominantly {100} surfaces, with small {110} facets according to the Wulff shape. The Young's modulus, the equilibrium length and the constrained residual stress of a series of prismatic beams of differing sizes are found to have size dependences that scale like the surface area to volume ratio for all but the smallest beam. The results are compared with a continuum model and the results of classical atomistic calculations based on an empirical potential. We attribute the size dependence to specific physical structures and interactions. In particular, the hydrogen interactions on the surface and the charge density variations within the beam are quantified and used both to parameterize the continuum model and to account for the discrepancies between the two models and the first-principles results.Comment: 14 pages, 10 figure

On-line transformer condition monitoring through diagnostics and anomaly detection

This paper describes the end-to-end components of an on-line system for diagnostics and anomaly detection. The system provides condition monitoring capabilities for two in- service transmission transformers in the UK. These transformers are nearing the end of their design life, and it is hoped that intensive monitoring will enable them to stay in service for longer. The paper discusses the requirements on a system for interpreting data from the sensors installed on site, as well as describing the operation of specific diagnostic and anomaly detection techniques employed. The system is deployed on a substation computer, collecting and interpreting site data on-line

Khapra beetle, Trogoderma granarium, Everts, intercepted at Vancouver, B.C.

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Cellular and biochemical characterisation of PrimPol, a novel eukaryotic primase-polymerase involved in DNA damage tolerance

Genome stability is of upmost importance to life. DNA polymerases are essential for the duplication and maintenance of the genome but they cannot themselves begin synthesis of a DNA chain, and require the activity of specialised RNA polymerases called primases. In eukaryotic cells distinct enzymes catalyse these two essential processes. This thesis contains the characterisation of coiled-coil domain containing protein (CCDC)111, a previously uncharacterised protein conserved in a broad range of unicellular and multicellular eukaryotes including humans. CCDC111 is a member of the archaeaoeukaroytic primase (AEP) superfamily and uniquely for a eukaryotic enzyme possesses both primase and polymerase activities, and was thus renamed PrimPol. The work in this thesis implicates PrimPol in the process of DNA damage tolerance, a universal mechanism by which cells complete genome duplication in spite of potentially lethal DNA damage. The first results chapters detail the essential role of a PrimPol homologue (TbPrimPol2) in the important protozoan pathogen Trypanosoma brucei. A combination of molecular, cell biology, and biochemical analyses indicate a role for TbPrimPol2 in the post-replication tolerance of endogenously occurring DNA damage using its trans-lesion DNA synthesis activity. The remaining results chapters characterise PrimPol in human cultured cells, and demonstrate that this enzyme is present in both the nucleus and mitochondria. In the nucleus PrimPol functions in the cellular tolerance of ultraviolet (UV)- induced DNA damage, and is required to protect xeroderma pigmentosum variant (XP-V) cells, deficient in the UV lesion bypass polymerase Pol !, from the cytotoxic affects of UV radiation. Together, this thesis establishes the involvement of PrimPol in DNA damage tolerance from one of the earliest diverging eukaryotic organisms to man

Measuring recovery in deaf, hard-of-hearing, and tinnitus patients in a mental health care setting:validation of the I.ROC

This study was aimed at validating the Individual Recovery Outcomes Counter (I.ROC) for deaf, hard-of-hearing, and tinnitus patients in a mental health care setting. There is a need for an accessible instrument to monitor treatment effects in this population. The I.ROC measures recovery, seeing recovery as a process of experiencing a meaningful life, despite the limitations caused by illness or disability. A total of 84 adults referred to 2 specialist mental health centers for deaf, hard-of-hearing, and tinnitus adults in the Netherlands completed the Dutch version of I.ROC and 3 other instruments. A total of 25 patients refused or did not complete the instruments: 50% of patients using sign language and 18% of patients using spoken language. Participants completed the measures at intake and then every 3 months. In this sample I.ROC demonstrated good internal consistency and convergent validity. Sensitivity to change was good, especially over a period of 6 or 9 months. This study provides preliminary evidence that the I.ROC is a valid instrument measuring recovery for hard-of-hearing and tinnitus patients using spoken language. For deaf patients using sign language, specifically those with limited language skills in spoken and written Dutch, more research is needed.</p

A Less Than Perfect Game, in a Less Than Perfect Place: The Critical Turn in Baseball Film

He can\u27t speak much English, but that\u27s the beauty of baseball. If he can go to his right and hit the broad side of a barn, that\u27ll do all his talking for him. — Big Leaguer, 1953 This reassuring voice-over, in reference to New York Giants minor league prospect Chuy Ramon Santiago Aguilar, sums up nicely fundamental tenet of baseball ideology: race, ethnicity, and cultural heritage do not matter. All are welcome to participate in the national pastime. All will be treated equally. All that matters is how one plays the game. Such has been the promise of America, as well, articulated in the values and aspirations of this, its national pastime

Ingot Hard Red Spring Wheat

This bulletin provides a brief overview of Ingot Hard Red Spring Wheat. Information regarding its origin, disease resistance, and other traits is provided

Oxen Hard Red Spring Wheat

This bulletin provides a brief overview of Oxen Hard Red Spring Wheat. Information regarding its origin, disease resistance, and other traits is provided