137 research outputs found

    A possible cosmological application of some thermodynamic properties of the black body radiation in n−n-dimensional Euclidean spaces

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    In this work we present the generalization of some thermodynamic properties of the black body radiation (BBR) towards an n−n-dimensional Euclidean space. For this case the Planck function and the Stefan-Boltzmann law have already been given by Landsberg and de Vos and some adjustments by Menon and Agrawal. However, since then no much more has been done on this subject and we believe there are some relevant aspects yet to explore. In addition to the results previously found we calculate the thermodynamic potentials, the efficiency of the Carnot engine, the law for adiabatic processes and the heat capacity at constant volume. There is a region at which an interesting behavior of the thermodynamic potentials arise, maxima and minima appear for the n−dn-d BBR system at very high temperatures and low dimensionality, suggesting a possible application to cosmology. Finally we propose that an optimality criterion in a thermodynamic framework could have to do with the 3−d3-d nature of the universe.Comment: 9 pages, 8 figure

    Stem and immune cells in colorectal primary tumour: Number and function of subsets may diagnose metastasis

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    An important percentage of colorectal cancer (CRC) patients will develop metastasis, mainly in the liver, even after a successful curative resection. This leads to a very high mortality rate if metastasis is not detected early on. Disseminated cancer cells develop from metastatic stem cells (MetSCs). Recent knowledge has accumulated about these cells particularly in CRC, so they may now be tracked from the removed primary tumour. This approach could be especially important in prognosis of metastasis because it is becoming clear that metastasis does not particularly rely on testable driver mutations. Among the many traits supporting an epigenetic amplification of cell survival and self-renewal mechanisms of MetSCs, the role of many immune cell populations present in tumour tissues is becoming clear. The amount of tumour-infiltrating lymphocytes (T, B and natural killer cells), dendritic cells and some regulatory populations have already shown prognostic value or to be correlated with disease-free survival time, mainly in immunohistochemistry studies of unique cell populations. Parallel analyses of these immune cell populations together with MetSCs in the primary tumour of patients, with later follow-up data of the patients, will define the usefulness of specific combinations of both immune and MetSCs cell populations. It is expected that these combinations, together to different biomarkers in the form of an immune score, may predict future tumour recurrences, metastases and/or mortality in CRC. It will also support the future design of improved immunotherapeutic approaches against metastasisS

    Oral hygiene might prevent cancer

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    Many evidences support that species from the Human Oral Microbiome Database such as Fusobacterium nucleatum or Bacteroides, linked previously to periodontitis and appendicitis, play a role in colorectal cancer (CRC), including metastasis. These typically oral species are invasive anaerobes that form biofilms in their virulent state. Aspirin (a NSAID) has been recently included into routine CRC prevention rationale. NSAIDs can prevent the growth of neoplastic lesions by inhibiting COX enzymes and another set of recently identified COX-independent targets, which include the WNT, AMPK and MTOR signaling pathways, the crosstalk between nucleoli and NF-κB transcriptional activity in apoptosis, and the biochemistry of platelets. These are signaling pathways related to tumor-promoting inflammation. In this process, pathogens or simple deregulation of the microbiota play an important role in CRC. Aspirin and other NSAIDs are efficient inhibitors of biofilm formation and able to control periodontitis development preventing inflammation related to the microbiota of the gingival tissue, so its seems plausible to include this pathway in the mechanisms that aspirin uses to prevent CRC. We propose arguments suggesting that current oral hygiene methods and other future developments against periodontitis might prevent CRC and probably other cancers, alone or in combination with other options; and that the multidisciplinary studies needed to prove this hypothesis might be relevant for cancer preventionThis work was supported by the FEDER and Xunta de Galicia [grant number ED431D 2017/23 to the Galician Network for Colorectal Cancer Research (REGICC)]S

    Conversión de un motor marino diesel lento de control electrónico en motor dual

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    El objetivo del siguiente trabajo fin de grado es reconvertir un motor MAN ME o de control electrónico a inyección de gas o MAN ME-GI, dado que todo motor MAN ME puede ser reconvertido, analizaremos los elementos necesarios a mayores que necesita un motor electrónicamente controlado para su reconversión a motor dual. Este TFG comprende la modificación de todo motor marino diésel de dos tiempos, de bajas revoluciones, cruceta y sobrealimentado de la marca MAN Diesel & Turbo, bien sea controlado por eje de camones (MAN MC) o por control electrónico (MAN ME).Traballo fin de grao (UDC.ETSNEM). Tecnoloxías Mariñas. Enerxía e Propulsión. Curso 2014/201

    Análisis de las relaciones sociales del alumnado a través del juego cooperativo

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    Las relaciones sociales que se establecen entre niños y niñas en las sesiones de Educación Física son escasas, ya que los niños tienen mayor protagonismo y las niñas ocupan un segundo plano. Por ello, desde el principio de igualdad, consideramos importante desarrollar diferentes habilidades sociales a través del juego cooperativo, ya que es un recurso que, según diversos autores, implica la participación de todo el alumnado y transmite valores como la solidaridad, la ayuda mutua o la empatía. Aunque por un lado hemos analizado las distintas conductas que se generan a través del juego cooperativo, no hemos podido detectar diferencias en las relaciones sociales antes y después de nuestra intervención.Grado en Educación Primari

    Supertubes versus superconducting tubes

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    In this paper we show the relationship between cylindrical D2-branes and cylindrical superconducting membranes described by a generic effective action at the bosonic level. In the first case the extended objects considered, arose as blown up type IIA superstrings to D2-branes, named supertubes. In the second one, the cosmological objects arose from some sort of field theories. The Dirac-Born-Infeld action describing supertubes is shown to be equivalent to the generic effective action describing superconducting membranes via a special transformation.Comment: Version with minor text changes with respect to the already publishe

    European Spallation Source as a searching tool for an ultralight scalar field

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    Dark matter (DM) nature is one of the major issues in physics. The search for a DM candidate has motivated the known proposal of an ultralight scalar field (ULSF). We explore the possibility to search for this ULSF at the upcoming European Spallation Source neutrino Super-Beam experiment. We have considered the recent study case in which there could be an interaction between the ULSF and active neutrinos. We have found that in this future experimental setup, the sensitivity is competitive with other neutrino physics experiments. We show the expected future sensitivity for the main parameter modeling the interaction between ULSF and neutrinos.Comment: 27 pages, 3 figures. Section added, extended discussion. To appear in PR

    Radiation damping of a Yang–Mills particle revisited

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    The problem of a colour-charged point particle interacting with a four-dimensional Yang–Mills gauge theory is revisited. The radiation damping is obtained inspired in Dirac’s computation. The difficulties in the non-abelian case were solved by using an ansatz for the Liénard–Wiechert potentials already used in the literature (Ö. Sarıoğlu. Phys. Rev. D, 66, 085005 (2002). doi:10.1103/PhysRevD.66.085005) for finding solutions to the Yang–Mills equations. Three non-trivial examples of radiation damping for a non-abelian particle are discussed in detail
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