324 research outputs found
Interannual to decadal time-scale variations in glacier mass balance [abstract]
EXTRACT (SEE PDF FOR FULL ABSTRACT):
The mass balance of glaciers depends on the seasonal variation in precipitation, temperature, and insolation. For glaciers in western North America, these meteorological variables are influenced by the large-scale atmospheric circulation over the northern Pacific Ocean. The purpose of this study is to gain a better understanding of the relationship between mass balance at glaciers in western North America and the large-scale atmospheric effects at interannual and decadal time scales
Determination of energy barrier profiles for high-k dielectric materials utilizing bias-dependent internal photoemission
We utilize bias-dependent internal photoemission spectroscopy to determine the metal/dielectric/silicon energy barrier profiles for Au/HfO2/Si and Au/Al2O3/Si structures. The results indicate that the applied voltage plays a large role in determining the effective barrier height and we attribute much of the variation in this case to image potential barrier lowering in measurements of single layers. By measuring current at both positive and negative voltages, we are able to measure the band offsets from Si and also to determine the flatband voltage and the barrier asymmetry at 0 V. Our SiO2 calibration sample yielded a conduction band offset value of 3.03+/-0.1 eV. Measurements on HfO2 give a conduction band offset value of 2.7+/-0.2 eV (at 1.0 V) and Al2O3 gives an offset of 3.3+/-0.1 (at 1.0 V). We believe that interfacial SiO2 layers may dominate the electron transport from silicon for these films. The Au/HfO2 barrier height was found to be 3.6+/-0.1 eV while the Au/Al2O3 barrier is 3.5+/-0.1 eV
Time Series Measurements of Chlorophyll Fluorescence in the Oceanic Bottom Boundary Layer With a Multisensor Fiber-Optic Fluorometer
An in situ multisensor fiber-optic fluorometer (MFF) has been developed to acquire long-term chlorophyll fluorescence measurements in the oceanic bottom boundary layer to characterize the finescale pigment structure at vertical spatial scales comparable to physical measurements. The eight fluorescence sensors of the MFF are composed of dual optical fibers of varying lengths (1.5-8 m), with the fiber ends oriented at 30 degrees to each other and enclosed by a small light baffle. Strobe excitation blue light is passed through one of each pair of optical fibers and stimulated chlorophyll fluorescence is carried back to a photomultiplier. Two sets of four fluorescence sensors assigned to high- and low-sensitivity photomultiplier detectors enable chlorophyll a measurements in two ranges, 0-50 mg m(-3) and 0-200 mg m(-3), respectively. Aspects of the design of the fiber-optic sensor are described that were intended to optimize detection of fluorescence signals and minimize interference by ambient light. The fiber-optic sensor outputs were stable with minimal instrument drift during long-term field operations, and measurements were not affected by turbidity and ambient light. A vertical array of fiber-optic fluorescence sensors supported on a tripod has been deployed at coastal sites for up to seven weeks and chlorophyll fluorescence was obtained with sufficiently high vertical spatial and temporal resolution
Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial
Date of acceptance: 01/07/2015 © 2015 Witham et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Acknowledgements UK NIHR HTA grant 10/71/01. We acknowledge the financial support of NHS Research Scotland in conducting this trial.Peer reviewedPublisher PD
Linguistic measures of chemical diversity and the "keywords" of molecular collections
Computerized linguistic analyses have proven of immense value in comparing and searching through large text collections ("corpora"), including those deposited on the Internet-indeed, it would nowadays be hard to imagine browsing the Web without, for instance, search algorithms extracting most appropriate keywords from documents. This paper describes how such corpus-linguistic concepts can be extended to chemistry based on characteristic "chemical words" that span more than traditional functional groups and, instead, look at common structural fragments molecules share. Using these words, it is possible to quantify the diversity of chemical collections/databases in new ways and to define molecular "keywords" by which such collections are best characterized and annotated
Recommended from our members
The stability of ecosystems: a brief overview of the paradox of enrichment
In theory, enrichment of resource in a predator-prey model leads to destabilization of the system, thereby collapsing the trophic interaction, a phenomenon referred to as "the paradox of enrichment". After it was first proposed by Rosenzweig (1971), a number of subsequent studies were carried out on this dilemma over many decades. In this article, we review these theoretical and experimental works and give a brief overview of the proposed solutions to the paradox. The mechanisms that have been discussed are modifications of simple predator-prey models in the presence of prey that is inedible, invulnerable, unpalatable and toxic. Another class of mechanisms includes an incorporation of a ratio-dependent functional form, inducible defence of prey and density-dependent mortality of the predator. Moreover, we find a third set of explanations based on complex population dynamics including chaos in space and time. We conclude that, although any one of the various mechanisms proposed so far might potentially prevent destabilization of the predator-prey dynamics following enrichment, in nature different mechanisms may combine to cause stability, even when a system is enriched. The exact mechanisms, which may differ among systems, need to be disentangled through extensive field studies and laboratory experiments coupled with realistic theoretical models
Exhumed hydrocarbon-seep authigenic carbonates from Zakynthos island (Greece): Concretions not archaeological remains
In Zakynthos Island (Greece), authigenic cementation of marine sediment has formed pipelike, disc and doughnut-shaped concretions. The concretions are mostly composed of authigenic ferroan dolomite accompanied by pyrite. Samples with >80% dolomite, have stable isotope compositions in two groups. The more indurated concretions have δ 18O around +4‰ and δ 13C values between -8 and -29‰ indicating dolomite forming from anaerobic oxidation of thermogenic methane (hydrocarbon seep), in the sulphate-methane transition zone. The outer surfaces of some concretions, and the less-cemented concretions, typically have slightly heavier isotopic compositions and may indicate that concretion growth progressed from the outer margin in the ambient microbially-modified marine pore fluids, inward toward the central conduit where the isotopic compositions were more heavily influenced by the seep fluid. Sr isotope data suggest the concretions are fossil features, possibly of Pliocene age and represent an exhumed hydrocarbon seep plumbing system. Exposure on the modern seabed in the shallow subtidal zone has caused confusion, as concretion morphology resembles archaeological stonework of the Hellenic period
Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries.
Distributing junctional components around the cell periphery is key for epithelial tissue morphogenesis and homeostasis. We discovered that positioning of dynamic microtubules controls the asymmetric accumulation of E-cadherin. Microtubules are oriented preferentially along the dorso-ventral axis in Drosophila melanogaster embryonic epidermal cells, and thus more frequently contact E-cadherin at dorso-ventral cell-cell borders. This inhibits RhoGEF2, reducing membrane recruitment of Rho-kinase, and increasing a specific E-cadherin pool that is mobile when assayed by fluorescence recovery after photobleaching. This mobile E-cadherin is complexed with Bazooka/Par-3, which in turn is required for normal levels of mobile E-cadherin. Mobile E-cadherin-Bazooka prevents formation of multicellular rosette structures and cell motility across the segment border in Drosophila embryos. Altogether, the combined action of dynamic microtubules and Rho signaling determines the level and asymmetric distribution of a mobile E-cadherin-Bazooka complex, which regulates cell behavior during the generation of a patterned epithelium
- …