How to determine fining behaviour in court? Game theoretical and empirical analysis

We build a structural model to understand the fine set in court, which is described as the outcome of a two-stage game between defendant, public prosecutor and judge. The equilibrium fine depends on the harm caused, the costs to society and the probalility that the quilty party is punished. This fine influences the severity of prosecution and the defence expenditures. Next we empirically analyse the fines pronounced by the Court of Appeal in Ghent (Belgium) for water related criminal offences. We investigate whether the seriousness of the violation and past convictions, as well as some other characteristics, increase the penalty.

Using emission standards under incomplete compliance

Using the case study of water pollution in the Flemish textile industry, we discuss three empirical questions concerning the use of emission standards. We find that the Becker result ("maximal fine / minimal inspection") does not hold if we include rule making, implementation and enforcement costs into the model. There is a balance between the fine and the inspection variables. Making enforcement more stringent does not mean to put the fine levels as high as possible and only then increase the inspections. We have also shown that is extremely important to have correct estimates of people's willingness to pay for environmental improvement. These WTP estimates determine in great part the optimal environmental strategy and its associated optimal monitoring and enforcement policy. Moreover, it really pays off to optimise the monitoring and enforcement strategy associated with an emission standard. This optimisation does not necessarily mean that monitoring and enforcement should be as stringent as possible. It is often possible to obtain the desired result by some intermediate value of the monitoring and enforcement parameters. This is due to the balancing of costs and benefits associated with monitoring and enforcement.Environmental Law; Illegal behaviour; Enforcement of Law

Judicial policy lines in the criminal sanctioning of environmental offenses: an empirical study.

We analyze judicial policy lines concerning criminal environmental sanctioning using a unique European dataset of individual criminal cases, including case-specific information on offenses and offenders. We investigate policy choices made by criminal judges in lower courts as well as the relevant court of appeal. The sanctioning policy of judges proofs to be varied as well as consistent. Judges decide to postpone convictions for cases they deem less important. They carefully balance effective and suspended sanctions, in general using them as substitutes, but in specific cases opting to use them cumulatively. Overall, judges in lower courts balance environmental and classic criminal law and aim at protecting individuals and their possessions as well as the environment.

Sanctioning of environmental crime in the European Union : the case of Flanders, Belgium

© 2018, Springer Science+Business Media B.V., part of Springer Nature. The development of the criminal sanctioning track in the EU is a prominent policy issue. Studies of the actual use of criminal sanctions in the member states are very important since the gap between the law and practice can be very wide. Policy makers and law enforcers are confronted with a lack of empirical data on the actual use of criminal law to sanction environmental offenses. In this paper, we use information stored in the Environmental LawForce database, which is a database of environmental sanctioning by criminal courts in Flanders, Belgium. The study distinguishes three types of offenders: companies, individuals prosecuted for acts committed as part of their professional activities, and individuals prosecuted for acts committed as part of their private lives. Based on previous theoretical insights, we investigate when we expect the environmental sanctions to be similar or different across the three groups of offenders. In particular, we assess the differences and similarities across the sanctioning of environmental offenses committed by companies, professional individuals and private individuals in Flanders.status: publishe

Pourquoi commencer ? L’initiation à l’injection de drogues selon les jeunes de la rue

Dans le cadre du développement d’une campagne de prévention du passage à l’injection de drogues chez les jeunes de la rue, nous avons mené sept groupes de discussion auprès de 37 d’entre eux âgés de 15 à 23 ans. L’analyse, à la fois déductive et inductive, a permis d’identifier les dimensions reflétant le point de vue des jeunes à propos de l’injection de drogues et des éléments qui favorisent le passage à l’injection dans leur milieu. Les résultats montrent que l’injection est généralement désapprouvée par les jeunes de la rue. Plusieurs ont des réserves, celles-ci étant liées aux conséquences négatives de l’injection. Ce que les jeunes redoutent le plus, c’est de devenir « accro », un risque qu’ils associent davantage à l’injection qu’aux autres modes de consommation. Malgré la désapprobation générale, au contact des utilisateurs de drogues par injection (UDI), il se produit une sorte de désensibilisation qui entraîne vers l’injection les plus vulnérables, soit les plus jeunes, surtout ceux qui satisfont leur besoin de sensations fortes à travers la drogue et recherchent une valorisation dans le monde de la rue. Divers éléments d’ordre individuel et social agissent alors pour amener ces jeunes à s’initier à l’injection. Plusieurs de ces éléments peuvent être modifiables par des interventions préventives.During the development of a media campaign, aimed at preventing initiation into injection drug use among street youth, we conducted seven focus groups with 37 youth aged between 15 and 23 years. The analysis process, at the same time deductive and inductive, permitted us to identify dimensions reflecting the viewpoint of street youth concerning injection drug use and the factors that favour initiation in their milieu. The results show that injection is generally disapproved of among street youth. Many have reservations because of the negative consequences linked to this behaviour. What youth fear most is becoming “an addict”, a risk that they associate especially with injection compared with other forms of drug use. Despite widespread disapproval, with continuing contact with injection drug user (IDUs), a kind of desensitization occurs which affects the most vulnerable youth, mainly the youngest, mostly those who satisfy their need for strong sensations through drugs and seek social valorisation in the street scene. Different factors, both on an individual level as well as a social level, influence these youth to start injecting. Some of these factors may be modifiable through preventive interventions.En el marco del desarrollo de una campaña de prevención del pasaje a la inyección de drogas en los jóvenes de la calle, hemos dirigido siete grupos de discusión en los que participaron 37 jóvenes de 15 a 23 años. El análisis, a la vez deductivo e inductivo, ha permitido identificar las dimensiones que reflejan el punto de vista de los jóvenes sobre la inyección de drogas y los elementos que favorecen el pasaje a la inyección en su medio. Los resultados muestran que los jóvenes de la calle desaprueban en general el uso de la inyección. Muchos de ellos tienen reservas sobre las consecuencias negativas de la inyección y lo que más temen es devenir adictos, riesgo que asocian a la inyección de drogas más que a cualquier otro modo de consumo. A pesar del rechazo general, en el contacto con los usuarios de droga por inyección (UDI) se produce un tipo de desensibilización que atrae hacia la inyección a los más vulnerables, es decir, a los más jóvenes, sobre todo los que satisfacen su necesidad de sensaciones fuertes a través de la droga y que buscan una valorización en el mundo de la calle. Actúan entonces diversos elementos de naturaleza individual y social que llevan a estos jóvenes a iniciarse en las drogas inyectables. Muchos de estos elementos pueden modificarse mediante intervenciones preventivas

Applicability of the bulk-transfer approach to estimate evapotranspiration from boreal peatlands

In northern landscapes, peatlands are widespread and their hydrological processes are complex. Furthermore, they are typically remote, limiting the amount and accuracy of in situ measurements. This is especially the case for evapotranspiration ET, which strongly influences watershed hydrology. The objective of this paper is to demonstrate the validity of the bulk-transfer approach to estimate ET over boreal peatlands. The simplicity of the model relies on four assumptions: (i) near-neutral atmospheric conditions; (ii) wet surface; (iii) constant momentum roughness length depending on vegetation height; and (iv) constant water vapor roughness length, with the last two assumptions implying a constant water vapor transfer coefficient CE. Using eddy covariance data from three Canadian peatlands—Necopastic (James Bay, Québec), Mer Bleue (Ottawa, Ontario), and Western Peatland (Athabasca, Alberta)—this paper shows that these sites are characterized by frequent occurrences of near-neutral atmospheric conditions, especially the Necopastic site, with nearly 76% of the 30-min data segments occurring under near-neutral stratification. The analysis suggests these near-neutral conditions occur as a result of strong mechanical turbulence and weak buoyancy effects. The bulk-transfer approach gives promising results for 30-min and daily ET in terms of mean error and correlation, with performances similar to the Penman equation, without requiring net radiation data. The accuracy of the approach is likely related to the number of near-neutral periods and the elevated position of the water table, which backs up the wet surface assumption

Establishment and development of the intestinal microbiota of preterm infants in a Lebanese tertiary hospital

© 2016 The Authors The establishment and development of the intestinal microbiota is known to be associated with profound short- and long-term effects on the health of full-term infants (FTI), but studies are just starting for preterm infants (PTI). The data also mostly come from western countries and little information is available for the Middle East. Here, we determined the composition and dynamics of the intestinal microbiota during the first month of life for PTI (n = 66) and FTI (n = 17) in Lebanon. Fecal samples were collected weekly and analyzed by quantitative PCR (q-PCR) and temporal temperature gradient gel electrophoresis (TTGE). We observed differences in the establishment and composition of the intestinal microbiota between the two groups. q-PCR showed that PTI were more highly colonized by Staphylococcus than FTI in the first three weeks of life; whereas FTI were more highly colonized by Clostridium clusters I and XI. At one month of life, PTI were mainly colonized by facultative anaerobes and a few strict anaerobes, such as Clostridium cluster I and Bifidobacterium. The type of feeding and antibiotic treatments significantly affected intestinal colonization. TTGE revealed low species diversity in both groups and high inter-individual variability in PTI. Our findings show that PTI had altered intestinal colonization with a higher occurrence of potential pathogens (Enterobacter, Clostridium sp) than FTI. This suggests the need for intervention strategies for PTI to modulate their intestinal microbiota and promote their health

ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target

<p>Abstract</p> <p>Background</p> <p>ASPM (<it>Abnormal Spindle-like Microcephaly associated</it>) over-expression was recently implicated in the development of malignant gliomas.</p> <p>Results</p> <p>To better characterize the involvement of ASPM in gliomas, we investigated the mRNA expression in 175 samples, including 8 WHO Grade II, 75 WHO Grade III and 92 WHO Grade IV tumors. <it>Aspm </it>expression was strongly correlated with tumor grade and increased at recurrence when compared to the initial lesion, whatever the initial grade of the primary tumor. ASPM expression also increased over serial passages in gliomaspheres <it>in vitro </it>and in mouse xenografts <it>in vivo</it>. Lentivirus-mediated shRNA silencing of ASPM resulted in dramatic proliferation arrest and cell death in two different gliomasphere models.</p> <p>Conclusion</p> <p>These data suggest that ASPM is involved in the malignant progression of gliomas, possibly through expansion of a cancer stem cell compartment, and is an attractive therapeutic target in glioblastoma multiforme.</p

The Biobanque québécoise de la COVID-19 (BQC19)—A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories

SARS-CoV-2 infection causing the novel coronavirus disease 2019 (COVID–19) has been responsible for more than 2.8 million deaths and nearly 125 million infections worldwide as of March 2021. In March 2020, the World Health Organization determined that the COVID–19 outbreak is a global pandemic. The urgency and magnitude of this pandemic demanded immediate action and coordination between local, regional, national, and international actors. In that mission, researchers require access to high-quality biological materials and data from SARS-CoV-2 infected and uninfected patients, covering the spectrum of disease manifestations. The “Biobanque québécoise de la COVID-19” (BQC19) is a pan–provincial initiative undertaken in Québec, Canada to enable the collection, storage and sharing of samples and data related to the COVID-19 crisis. As a disease-oriented biobank based on high-quality biosamples and clinical data of hospitalized and non-hospitalized SARS-CoV-2 PCR positive and negative individuals. The BQC19 follows a legal and ethical management framework approved by local health authorities. The biosamples include plasma, serum, peripheral blood mononuclear cells and DNA and RNA isolated from whole blood. In addition to the clinical variables, BQC19 will provide in-depth analytical data derived from the biosamples including whole genome and transcriptome sequencing, proteome and metabolome analyses, multiplex measurements of key circulating markers as well as anti-SARS-CoV-2 antibody responses. BQC19 will provide the scientific and medical communities access to data and samples to better understand, manage and ultimately limit, the impact of COVID-19. In this paper we present BQC19, describe the process according to which it is governed and organized, and address opportunities for future research collaborations. BQC19 aims to be a part of a global communal effort addressing the challenges of COVID–19