3,502 research outputs found
Temporal Model Adaptation for Person Re-Identification
Person re-identification is an open and challenging problem in computer
vision. Majority of the efforts have been spent either to design the best
feature representation or to learn the optimal matching metric. Most approaches
have neglected the problem of adapting the selected features or the learned
model over time. To address such a problem, we propose a temporal model
adaptation scheme with human in the loop. We first introduce a
similarity-dissimilarity learning method which can be trained in an incremental
fashion by means of a stochastic alternating directions methods of multipliers
optimization procedure. Then, to achieve temporal adaptation with limited human
effort, we exploit a graph-based approach to present the user only the most
informative probe-gallery matches that should be used to update the model.
Results on three datasets have shown that our approach performs on par or even
better than state-of-the-art approaches while reducing the manual pairwise
labeling effort by about 80%
Vectorial Control of Magnetization by Light
Coherent light-matter interactions have recently extended their applications
to the ultrafast control of magnetization in solids. An important but
unrealized technique is the manipulation of magnetization vector motion to make
it follow an arbitrarily designed multi-dimensional trajectory. Furthermore,
for its realization, the phase and amplitude of degenerate modes need to be
steered independently. A promising method is to employ Raman-type nonlinear
optical processes induced by femtosecond laser pulses, where magnetic
oscillations are induced impulsively with a controlled initial phase and an
azimuthal angle that follows well defined selection rules determined by the
materials' symmetries. Here, we emphasize the fact that temporal variation of
the polarization angle of the laser pulses enables us to distinguish between
the two degenerate modes. A full manipulation of two-dimensional magnetic
oscillations is demonstrated in antiferromagnetic NiO by employing a pair of
polarization-twisted optical pulses. These results have lead to a new concept
of vectorial control of magnetization by light
Effects of a 1-Week Inpatient Course Including Information, Physical Activity, and Group Sessions for Prostate Cancer Patients
This study aims to explore the effects of a 1-week inpatient course including information, physical activity (PA), and group sessions on physical and mental health-related outcomes for prostate cancer (PCa) patients. Further to assess the patients’ satisfaction with the course. PCa patients completed a questionnaire assessing PA, fatigue, mental distress, and quality of life 1 month before (T0) and 3 months after (T1) the course. Total fatigue, physical fatigue, and PSA anxiety decreased significantly from T0 to T1. No significant changes were observed in the other measures. The majority of the participants were satisfied with the course. In spite of minor reductions in fatigue and PSA anxiety and satisfied patients, the findings indicate that a 1-week inpatient course does not influence substantially on most of the health-related outcomes in PCa patients 3 months after the course
Exploring a Potential Interaction Between the Effect of Specific Maternal Smoking Patterns and Comorbid Antenatal Depression in Causing Postpartum Depression
Anthony J Kondracki,1 John R Attia,2 Matthew J Valente,3 Kimberly B Roth,1 Marshall Akin,4 Claire A McCarthy,5 Jennifer L Barkin1 1Department of Community Medicine, Mercer University School of Medicine, Savannah and Macon, GA, USA; 2School of Medicine and Public Health, The University of Newcastle, Callaghan, New South Wales, Australia; 3College of Public Health, University of South Florida, Tampa, FL, USA; 4Memorial Health University Medical Center, Savannah, GA, USA; 5School of Medicine, Mercer University, Savannah, GA, USACorrespondence: Anthony J Kondracki, Mercer University School of Medicine, Department of Community Medicine, 1250 East 66th Street, Savannah, GA, 31404, USA, Tel +1 912-721-8227, Fax +1 912-721-8267, Email [email protected]: To explore a potential interaction between the effect of specific maternal smoking patterns and the presence of antenatal depression, as independent exposures, in causing postpartum depression (PPD).Methods: This case–control study of participants with singleton term births (N = 51220) was based on data from the 2017– 2018 Pregnancy Risk Assessment Monitoring System. Multivariable log-binomial regression models examined the main effects of smoking patterns and self-reported symptoms of antenatal depression on the risk of PPD on the adjusted risk ratio (aRR) scale and tested a two-way interaction adjusting for covariates selected in a directed acyclic graph (DAG). The interaction effects were measured on the additive scale using relative excess risk due to interaction (RERI), the attributable proportion of interaction (AP), and the synergy index (SI). Causal effects were defined in a counterfactual framework. The E-value quantified the potential impact of unobserved/unknown covariates, conditional on observed covariates.Results: Among 6841 women in the sample who self-reported PPD, 35.7% also reported symptoms of antenatal depression. Out of 3921 (7.7%) women who reported smoking during pregnancy, 32.6% smoked at high intensity (≥ 10 cigarettes/day) in all three trimesters and 36.6% had symptoms of antenatal depression. The main effect of PPD was the strongest for women who smoked at high intensity throughout pregnancy (aRR 1.65; 95% CI: 1.63, 1.68). A synergistic interaction was detected, and the effect of all maternal smoking patterns was augmented, particularly in late pregnancy for Increasers and Reducers.Conclusion: Strong associations and interaction effects between maternal smoking patterns and co-occurring antenatal depression support smoking prevention and cessation interventions during pregnancy to lower the likelihood of PPD.Keywords: maternal smoking patterns, antenatal depression, postpartum depression, interaction, directed acyclic graph, DA
A systematic review of biomarkers for disease progression in Parkinson's disease
Peer reviewedPublisher PD
Towards learning and verifying invariants of cyber-physical systems by code mutation
Cyber-physical systems (CPS), which integrate algorithmic control with
physical processes, often consist of physically distributed components
communicating over a network. A malfunctioning or compromised component in such
a CPS can lead to costly consequences, especially in the context of public
infrastructure. In this short paper, we argue for the importance of
constructing invariants (or models) of the physical behaviour exhibited by CPS,
motivated by their applications to the control, monitoring, and attestation of
components. To achieve this despite the inherent complexity of CPS, we propose
a new technique for learning invariants that combines machine learning with
ideas from mutation testing. We present a preliminary study on a water
treatment system that suggests the efficacy of this approach, propose
strategies for establishing confidence in the correctness of invariants, then
summarise some research questions and the steps we are taking to investigate
them.Comment: Short paper accepted by the 21st International Symposium on Formal
Methods (FM 2016
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Feasibility of use of the anxiety thermometer in antenatal services
Of the 102 women approached, 101 (99%) completed the anxiety thermometer (AnxT). The women were aged between 22–44 years (mean age 34.5 years); about half were primigravida and half multigravida. Almost two-thirds rated their current anxiety as four or above out of a maximum of 10. The most frequently reported concern was health of baby, followed by fears and worries, tiredness, and sleep problems. The high participation rate suggests that the AnxT can be developed to screen anxiety and elicit perinatal and related concerns to facilitate consultation and appropriate triaging. The problem checklist was refined based on the current results
Cancer cells exploit an orphan RNA to drive metastatic progression.
Here we performed a systematic search to identify breast-cancer-specific small noncoding RNAs, which we have collectively termed orphan noncoding RNAs (oncRNAs). We subsequently discovered that one of these oncRNAs, which originates from the 3' end of TERC, acts as a regulator of gene expression and is a robust promoter of breast cancer metastasis. This oncRNA, which we have named T3p, exerts its prometastatic effects by acting as an inhibitor of RISC complex activity and increasing the expression of the prometastatic genes NUPR1 and PANX2. Furthermore, we have shown that oncRNAs are present in cancer-cell-derived extracellular vesicles, raising the possibility that these circulating oncRNAs may also have a role in non-cell autonomous disease pathogenesis. Additionally, these circulating oncRNAs present a novel avenue for cancer fingerprinting using liquid biopsies
Spatially Explicit Data: Stewardship and Ethical Challenges in Science
Scholarly communication is at an unprecedented turning point created in part by the increasing saliency of data stewardship and data sharing. Formal data management plans represent a new emphasis in research, enabling access to data at higher volumes and more quickly, and the potential for replication and augmentation of existing research. Data sharing has recently transformed the practice, scope, content, and applicability of research in several disciplines, in particular in relation to spatially specific data. This lends exciting potentiality, but the most effective ways in which to implement such changes, particularly for disciplines involving human subjects and other sensitive information, demand consideration. Data management plans, stewardship, and sharing, impart distinctive technical, sociological, and ethical challenges that remain to be adequately identified and remedied. Here, we consider these and propose potential solutions for their amelioration
Anthropometric indices of Gambian children after one or three annual rounds of mass drug administration with azithromycin for trachoma control.
BACKGROUND: Mass drug administration (MDA) with azithromycin, carried out for the control of blinding trachoma, has been linked to reduced mortality in children. While the mechanism behind this reduction is unclear, it may be due, in part, to improved nutritional status via a potential reduction in the community burden of infectious disease. To determine whether MDA with azithromycin improves anthropometric indices at the community level, we measured the heights and weights of children aged 1 to 4 years in communities where one (single MDA arm) or three annual rounds (annual MDA arm) of azithromycin had been distributed. METHODS: Data collection took place three years after treatment in the single MDA arm and one year after the final round of treatment in the annual MDA arm. Mean height-for-age, weight-for-age and weight-for-height z scores were compared between treatment arms. RESULTS: No significant differences in mean height-for-age, weight-for-age or weight-for-height z scores were found between the annual MDA and single MDA arms, nor was there a significant reduction in prevalence of stunting, wasting or underweight between arms. CONCLUSIONS: Our data do not provide evidence that community MDA with azithromycin improved anthropometric outcomes of children in The Gambia. This may suggest reductions in mortality associated with azithromycin MDA are due to a mechanism other than improved nutritional status
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