Atlantic mountain grassland-heathlands: structure and feeding value

Atlantic mountain pastures are composed by mosaics of semi-natural grasslands and heathlands. A knowledge of their structure and feeding value is useful to understand their livestock use and improve management of these communities. This study was carried out in the Gorbeia Natural Park in northern Spain. Pasture composition, sward height and nutritive value were measured over four grazing seasons (spring, summer, late summer and autumn) in three plant communities: grassland (GR), open heathland (OH) and dense heathland (DH). The grassland community had lower sward height and better nutritive value. In less favoured grazing periods, when sward height in GR becomes limiting livestock move to OH with higher pasture height and lower sward cover and nutritive value. Even both heathlands have similar height and quality, the selection of OH, and avoiding of the dense one, could be due to its higher sward cover, which could make it easier to look for feed. Moreover, considering the woody component the estimated nutritive value of DH does not cover the minimum required for livestock production

Development of a Sentinel-2 burned area algorithm: Generation of a small fire database for sub-Saharan Africa

A locally-adapted multitemporal two-phase burned area (BA) algorithm has been developed using as inputs Sentinel-2 MSI reflectance measurements in the short and near infrared wavebands plus the active fires detected by Terra and Aqua MODIS sensors. An initial burned area map is created in the first step, from which tile dependent statistics are extracted for the second step. The whole Sub-Saharan Africa (around 25 M km(2)) was processed with this algorithm at a spatial resolution of 20 m, from January to December 2016. This period covers two half fire seasons on the Northern Hemisphere and an entire fire season in the South. The area was selected as existing BA products account it to include around 70% of global BA. Validation of this product was based on a two-stage stratified random sampling of Landsat multitemporal images. Higher accuracy values than existing global BA products were observed, with Dice coefficient of 77% and omission and commission errors of 26.5% and 19.3% respectively. The standard NASA BA product (MCD64A1 c6) showed a similar commission error (20.4%), but much higher omission errors (59.6%), with a lower Dice coefficient (53.6%). The BA algorithm was processed over > 11,000 Sentinel-2 images to create a database that would also include small fires (< 100 ha). This is the first time a continental BA product is generated from medium resolution sensors (spatial resolution = 20 m), showing their operational potential for improving our current understanding of global fire impacts. Total BA estimated from our product was 4.9 M km(2), around 80% larger area than what the NASA BA product (MCD64A1 c6) detected in the same period (2.7 M km(2)). The main differences between the two products were found in regions where small fires (< 100 ha) account for a significant proportion of total BA, as global products based on coarse pixel sizes (500 m for MCD64A1) unlikely detect them. On the negative side, Sentinel-2 based products have lower temporal resolution and consequently are more affected by cloud/cloud shadows and have less temporal reporting accuracy than global BA products. The product derived from S2 imagery would greatly contribute to better understanding the impacts of small fires in global fire regimes, particularly in tropical regions, where such fires are frequent. This product is named FireCCISFD11 and it is publicly available at: https://www.esa-fire-cci.org/node/262, last accessed on November 2018.This research was carried out within the Fire_cci project (https://www.esa-fire-cci.org/, last accessed on November 2018), contract no. 4000115006/15/I-NB, which has been funded by the European Space Agency (ESA) under the Climate Change Initiative Programme. The FireCCISFD11 product can be downloaded at https://www.esa-fire-cci.org/node/262 (last accessed on November 2018)

[(4R,5R)-(2,2-Dimethyl-1,3-dioxolane-4,5-di­yl)bis­(diphenyl­methano­lato)-κ2 O:O′]bis(N-methyl­methanamin­ato)titanium(IV)

In the title four-coordinate complex, [Ti(C2H6N)2(C31H28O4)], two symmetry-independent mol­ecules are present in the asymmetric unit. The TiIV atom displays a distorted tetra­hedral geometry, with Ti—O bond lengths ranging from 1.805 (3) to 1.830 (3) Å and O—Ti—O ligand bite angles of 100.16 (12) and 101.36 (12)°. The short Ti—N bond distances, ranging from 1.877 (4) to 1.905 (4) Å, indicate strong bonding between the TiIV atom and the dimethyl­amide ligands

The Importance Of Monoclonal Proteins Determination For The Correct Diagnosis Of Transthyretin Cardiac Amyloidosis By [Tc-99m]Tc-diphosphonates

EPS-066 Aim/Introduction: To analyze the influence of the determination of free monoclonal proteins in blood and urine in the final diagnosis of Transthyretin Cardiac Amyloidosis (TTRA). Materials and Methods: We have analyzed 200 [99mTc]Tc-diphosphonates scans: 192 performed on 190 patients under suspicion of TTRA and 7 patients with grade II-III radiotracer myocardial deposit as a casual finding (November/2013 - January/2020). Likewise, clinical and laboratory characteristics (heart failure, LVEF, proBNP levels, immunofixation in serum and/or urine for the detection of monoclonal chains and chronic renal failure) have been evaluated. A positive case has been considered for TTRAwt or senile (Score Perugini II-III scan, negative immunofixation in serum and/or urine, negative genetic study), positive case for hereditary TTRA (Score Perugini II-III scan, negative immunofixation and positive genetic study), positive case for secondary amyloidosis (positive immunofixation and presence of hematologic malignancy) and undetermined amyloidosis (immunofixation not performed or positive and absence of haematologic malignancies at follow-up). Results: 59 positive scans have been detected, 47 men (79’7%) and 12 women (20’3%). The mean age of the group of positives was 82’66 years, while that of the negatives was 72’15. The mean proBNP levels in the positives are 7561, compared to 5869 in the negative group. Immunofixation (serum and/or urine for detection of kappa or lambda monoclonal chains at 30 (50.8%) has been performed on these patients. Finally, 37.2% (22/59) resulted in ATTRwt, 3.4% (2/59) hereditary ATTR (genetic study: variant E54Q and mutation c.424> A (p.Va.122Ile) in exon 4 of TTR) and 1.7% (1/59) secondary amyloidosis. The remaining 34/59 (57.7%) cases were undetermined amyloidosis (6 positive immunofixation and 27 without monoclonal proteins determination). Conclusion: Determination of monoclonal bands in blood and urine is mandatory to correctly characterize cases of cardiac amyloidosis and, in presence of monoclonal bands, to assess the existence of underlying haematological malignancies

Impact Of Sentinel Lymph Node Biopsy In Breast Cancer Patients Treated With Neoadjuvant Chemotherapy

EPS 196 Aim/Introduction: To analyze how many of the patients undergoing neoadjuvant chemotherapy (NCT) may benefit from SLNB, as well as the impact on patient management, especially in those with early axillary involvement. Materials and Methods: We included patients with breast carcinoma candidates to NCT discussed at the Tumor Committee of our hospital (April/2017-August/2019). All of them were subjected to clinical assessment, ultrasound and, if appropriate, histological analysis, axillary pre and post- NCT. Sentinel lymph node detection was performed after periareolar injection of [99mTc]Tc-nanocoloid (74 MBq) the day before surgery. In some cases, blue dye was injected and/or a pre-NPC metal clip was placed in the affected node. Results: Sixty-two patients were included. NCT achieved a complete breast response in 12 patients, partial in 46 and non-response in 4. Initially, 31 patients were classified as N0 and 31 as N+ (28 N1 and 3 N2), achieving a complete axillary response in 58% of N+ (18). SLNB was performed in 49 patients (79%; 100% in N0 and 58% in N+ from baseline). The gamma detection rate of the sentinel lymph node was 91.8% (93.5% in N0 and 88.9% in N+). 28 lymphadenectomies were undergone (45.2%; 22.5% in N0 and 67.7% in N+), 11 due to positive SLNB (5 N0 and 6 N1), 13 owing to lack of axillary response and 4 caused by the non-localization of the sentinel lymph node. SLNB was performed in 58% of N+ patients, of which 44.4% were negative, avoiding lymphadenectomy. Metal clip and/or blue dye techniques were used in 31 cases (50%). Conclusion: SLNB is viable in a high percentage of patients with previous NCT, with a high detection rate, even in patients with early affected axilla, avoiding lymphadenectomy to patients who achieve a complete response of the axillary lymph node

Recent advances in digital coincidence counting for Radionuclide Metrology

Conference of 2013 3rd International Conference on Advancements in Nuclear Instrumentation, Measurement Methods and Their Applications, ANIMMA 2013 ; Conference Code:102802International audienceThe radioactivity measurement techniques developed within the EURAMET EMRP 'MetroFission' Joint Research Project, were aimed at performing on-site activity measurements at the primary standard level (4πβ-γ coincidence counting) for a wide range of radionuclides utilizing recent advances in high-speed digital sampling and digital signal processing. The state-of-the-art technology employed within this project provides up to 14-bit digitizer systems operating with sampling rates in the order of 108 to 109 samples-per-second, incorporating on-board FPGA devices, which greatly enhances the application of digital signal processing for the implementation of digital coincidence counting. These devices when coupled to suitable analysis software, demonstrate a significant improvement in the provision of primary standards of radioactivity. This manuscript provides a description of the systems employed, along with recommendations regarding optimization of the digital sampling of signals from photo-multiplier tubes and pre-amplifiers and compare the benefits of 'off-line' versus 'on-line' 4πβ-γ digital coincidence counting systems

Development of a Sentinel-2 burned area algorithm: Generation of a small fire database for sub-Saharan Africa

A locally-adapted multitemporal two-phase burned area (BA) algorithm has been developed using as inputs Sentinel-2 MSI reflectance measurements in the short and near infrared wavebands plus the active fires detected by Terra and Aqua MODIS sensors. An initial burned area map is created in the first step, from which tile dependent statistics are extracted for the second step. The whole Sub-Saharan Africa (around 25 M km(2)) was processed with this algorithm at a spatial resolution of 20 m, from January to December 2016. This period covers two half fire seasons on the Northern Hemisphere and an entire fire season in the South. The area was selected as existing BA products account it to include around 70% of global BA. Validation of this product was based on a two-stage stratified random sampling of Landsat multitemporal images. Higher accuracy values than existing global BA products were observed, with Dice coefficient of 77% and omission and commission errors of 26.5% and 19.3% respectively. The standard NASA BA product (MCD64A1 c6) showed a similar commission error (20.4%), but much higher omission errors (59.6%), with a lower Dice coefficient (53.6%). The BA algorithm was processed over > 11,000 Sentinel-2 images to create a database that would also include small fires (< 100 ha). This is the first time a continental BA product is generated from medium resolution sensors (spatial resolution = 20 m), showing their operational potential for improving our current understanding of global fire impacts. Total BA estimated from our product was 4.9 M km(2), around 80% larger area than what the NASA BA product (MCD64A1 c6) detected in the same period (2.7 M km(2)). The main differences between the two products were found in regions where small fires (< 100 ha) account for a significant proportion of total BA, as global products based on coarse pixel sizes (500 m for MCD64A1) unlikely detect them. On the negative side, Sentinel-2 based products have lower temporal resolution and consequently are more affected by cloud/cloud shadows and have less temporal reporting accuracy than global BA products. The product derived from S2 imagery would greatly contribute to better understanding the impacts of small fires in global fire regimes, particularly in tropical regions, where such fires are frequent. This product is named FireCCISFD11 and it is publicly available at: https://www.esa-fire-cci.org/node/262, last accessed on November 2018.This research was carried out within the Fire_cci project (https://www.esa-fire-cci.org/, last accessed on November 2018), contract no. 4000115006/15/I-NB, which has been funded by the European Space Agency (ESA) under the Climate Change Initiative Programme. The FireCCISFD11 product can be downloaded at https://www.esa-fire-cci.org/node/262 (last accessed on November 2018)