XMM-Newton Spectra of Intermediate-Mass Black Hole Candidates: Application of a Monte-Carlo Simulated Model

We present a systematic spectral analysis of six ultraluminous X-ray sources (NGC1313 X-1/X-2, IC342 X-1, HoIX X-1, NGC5408 X-1 and NGC3628 X-1) observed with XMM-Newton Observatory. These extra-nuclear X-ray sources in nearby late-type galaxies have been considered as intermediate-mass black hole candidates. We have performed Monte-Carlo simulations of Comptonized multi-color black-body accretion disks. This unified and self-consistent spectral model assumes a spherically symmetric, thermal corona around each disk and accounts for the radiation transfer in the Comptonization. We find that the model provides satisfactory fits to the XMM-Newton spectra of thesources. The characteristic temperatures of the accretion disks (T_in), for example, are in the range of ~ 0.05-0.3 keV, consistent with the intermediate-mass black hole interpretation. We find that the black hole mass is typically about a few times 10^3 M_\odot and has an accretion rate ~ 10^{-6} - 10^{-5} M_\odot yr^{-1}. For the spectra considered here, we find that the commonly used multi-color black-body accretion disk model with an additive power law component, though not physical, provides a good mathematical approximation to the Monte-Carlo simulated model. However, the latter model provides additional constraints on the properties of the accretion systems, such as the disk inclination angles and corona optical depths.Comment: 23 pages, 4 figures, 5 tables. ApJ accepted, July 2004 issu

An Optical Study of Stellar and Interstellar Environments of Seven Luminous and Ultraluminous X-Ray Sources

We have studied the stellar and interstellar environments of two luminous X-ray sources and five ultraluminous X-ray sources (ULXs) in order to gain insight into their nature. Archival Hubble Space Telescope images were used to identify the optical counterparts of the ULXs Ho IX X-1 and NGC 1313 X-2, and to make photometric measurements of the local stellar populations of these and the luminous source IC 10 X-1. We obtained high-dispersion spectroscopic observations of the nebulae around these seven sources to search for He II lambda-4686 emission and to estimate the expansion velocities and kinetic energies of these nebulae. Our observations did not detect nebular He II emission from any source, with the exception of LMC X-1; this is either because we missed the He III regions or because the nebulae are too diffuse to produce He II surface brightnesses that lie within our detection limit. We compare the observed ionization and kinematics of the supershells around the ULXs Ho IX X-1 and NGC 1313 X-2 with the energy feedback expected from the underlying stellar population to assess whether additional energy contributions from the ULXs are needed. In both cases, we find insufficient UV fluxes or mechanical energies from the stellar population; thus these ULXs may be partially responsible for the ionization and energetics of their supershells. All seven sources we studied are in young stellar environments and six of them have optical counterparts with masses >~7 M_sun; thus, these sources are most likely high-mass X-ray binaries.Comment: 30 pages, 9 figures. Numerous minor revisions, primarily to more accurately cite earlier work by Pakull and Mirioni, and to correct typographical errors. Removed a misleading sentence in the Introduction (re: X-ray photoionization by ULXs). Accepted for publication in The Astrophysical Journal. Figures have been reduced in resolution for space requirements; full-resolution figures may be requested by email to [email protected]

An Optical Study of Stellar and Interstellar Environments of Seven Luminous and Ultraluminous X-Ray Sources

We have studied the stellar and interstellar environments of two luminous X-ray sources and five ultraluminous X-ray sources (ULXs) in order to gain insight into their nature. Archival Hubble Space Telescope images were used to identify the optical counterparts of the ULXs Ho IX X-1 and NGC 1313 X-2, and to make photometric measurements of the local stellar populations of these and the luminous source IC 10 X-1. We obtained high-dispersion spectroscopic observations of the nebulae around these seven sources to search for He II lambda-4686 emission and to estimate the expansion velocities and kinetic energies of these nebulae. Our observations did not detect nebular He II emission from any source, with the exception of LMC X-1; this is either because we missed the He III regions or because the nebulae are too diffuse to produce He II surface brightnesses that lie within our detection limit. We compare the observed ionization and kinematics of the supershells around the ULXs Ho IX X-1 and NGC 1313 X-2 with the energy feedback expected from the underlying stellar population to assess whether additional energy contributions from the ULXs are needed. In both cases, we find insufficient UV fluxes or mechanical energies from the stellar population; thus these ULXs may be partially responsible for the ionization and energetics of their supershells. All seven sources we studied are in young stellar environments and six of them have optical counterparts with masses >~7 M_sun; thus, these sources are most likely high-mass X-ray binaries.Comment: 30 pages, 9 figures. Numerous minor revisions, primarily to more accurately cite earlier work by Pakull and Mirioni, and to correct typographical errors. Removed a misleading sentence in the Introduction (re: X-ray photoionization by ULXs). Accepted for publication in The Astrophysical Journal. Figures have been reduced in resolution for space requirements; full-resolution figures may be requested by email to [email protected]

Crew Procedures for Continuous Descent Arrivals Using Conventional Guidance

This paper presents results from a simulation study which investigated the use of Continuous Descent Arrival (CDA) procedures for conducting a descent through a busy terminal area, using conventional transport-category automation. This research was part of the Low Noise Flight Procedures (LNFP) element within the Quiet Aircraft Technology (QAT) Project, that addressed development of flight guidance, and supporting pilot and Air Traffic Control (ATC) procedures for low noise operations. The procedures and chart were designed to be easy to understand, and to make it easy for the crew to make changes via the Flight Management Computer Control-Display Unit (FMC-CDU) to accommodate changes from ATC. The test runs were intended to represent situations typical of what exists in many of today's terminal areas, including interruptions to the descent in the form of clearances issued by ATC

Neuroprotective efficacy of P7C3 compounds in primate hippocampus.

There is a critical need for translating basic science discoveries into new therapeutics for patients suffering from difficult to treat neuropsychiatric and neurodegenerative conditions. Previously, a target-agnostic in vivo screen in mice identified P7C3 aminopropyl carbazole as capable of enhancing the net magnitude of postnatal neurogenesis by protecting young neurons from death. Subsequently, neuroprotective efficacy of P7C3 compounds in a broad spectrum of preclinical rodent models has also been observed. An important next step in translating this work to patients is to determine whether P7C3 compounds exhibit similar efficacy in primates. Adult male rhesus monkeys received daily oral P7C3-A20 or vehicle for 38 weeks. During weeks 2-11, monkeys received weekly injection of 5'-bromo-2-deoxyuridine (BrdU) to label newborn cells, the majority of which would normally die over the following 27 weeks. BrdU+ cells were quantified using unbiased stereology. Separately in mice, the proneurogenic efficacy of P7C3-A20 was compared to that of NSI-189, a proneurogenic drug currently in clinical trials for patients with major depression. Orally-administered P7C3-A20 provided sustained plasma exposure, was well-tolerated, and elevated the survival of hippocampal BrdU+ cells in nonhuman primates without adverse central or peripheral tissue effects. In mice, NSI-189 was shown to be pro-proliferative, and P7C3-A20 elevated the net magnitude of hippocampal neurogenesis to a greater degree than NSI-189 through its distinct mechanism of promoting neuronal survival. This pilot study provides evidence that P7C3-A20 safely protects neurons in nonhuman primates, suggesting that the neuroprotective efficacy of P7C3 compounds is likely to translate to humans as well

Is there a fetal origin of depression? Evidence from the Mater University Study of Pregnancy and its outcomes

It is unclear whether there is a fetal origin of adult depression. In particular, previous studies have been unable to adjust for the potential effect of maternal depression during pregnancy on any association. The association of birth weight with adult symptoms of depression was examined in an Australian prospective birth cohort, the Mater University Study of Pregnancy and its outcomes. Depressive symptoms were assessed with the Center for Epidemiologic Studies Depression Scale among 3,719 participants at the 21-year follow-up in 2002-2005. In multivariable analyses, there were a weak inverse association between birth weight and symptoms of depression in the whole cohort and some evidence of sex differences in this association. Among females, there was a graded inverse association: In the fully adjusted model, the odds ratio for a high level of depressive symptoms for a 1-standard deviation increase in birth weight (gestational age-standardized z score) was 0.82 (95% confidence interval: 0.73, 0.92). Among males, there was no association (with sex in all models: p(interaction) < 0.004). Study results provide some support for a fetal origin of adult depression and suggest that the association is not explained by maternal mental health characteristics during pregnancy. Further research is needed to better understand the mechanisms underlying the association

The constant-velocity highly collimated outflows of the planetary nebula He 2-90

We present high-dispersion echelle spectroscopic observations and a narrow-band [N II] image of the remarkable jet-like features of He 2-90. They are detected in the echelle spectra in the H-alpha and [N II] lines but not in other nebular lines. The [N II]/H-alpha ratio is uniformly high, ~1. The observed kinematics reveals bipolar collimated outflows in the jet-like features and shows that the southeast (northwest) component expands towards (away from) the observer at a remarkably constant line-of-sight velocity, 26.0+-0.5 km/s. The observed expansion velocity and the opening angle of the jet-like features are used to estimate an inclination angle of ~5 degrees with respect to the sky plane and a space expansion velocity of ~290 km/s. The spectrum of the bright central nebula reveals a profusion of Fe lines and extended wings of the H-alpha line, similar to those seen in symbiotic stars and some young planetary nebulae that are presumed to host a mass-exchanging binary system. If this is the case for He 2-90, the constant velocity and direction of the jets require a very stable dynamic system against precession and warping.Comment: 8 pages (emulate ApJ), 5 figure, 1 tabl

Diffuse Dark and Bright Objects in the Hubble Deep Field

In the Hubble Deep Field (HDF) we have identified candidate regions where primordial galaxies might be forming. These regions are identified from negative or positive peaks in the difference maps obtained from the HDF maps smoothed over 0.8'' and 4''. They have apparent V magnitudes typically between 29 and 31 (missing flux below the local average level for the dark objects). The identified objects are shown to be real by two ways. First, the cross-correlations of these peaks detected in different filters are strong. Second, their auto-correlation functions indicate that these faint diffuse objects are self-clustered. The subset of objects dark in the F450W and F606W bandpasses, but bright in F814W, also shows stronger correlation compared to the whole dark sample. This further supports that our samples are indeed physical objects. The amplitude and slope of the angular correlation function of the bright objects indicates that these objects are ancestors of the present nearby bright galaxies. We have inspected individual bright objects and noted that they have several tiny spots embedded in extended backgrounds. They are likely to be the primordial galaxies at high redshifts in the process of active star formation and merging. Our subset of dark objects is thought to be the `intergalactic dark clouds' he blocking the background far UV light (at the rest frame) at high redshifts instead of empty spaces between the first galaxies at the edge of the universe of galaxies.Comment: ApJ, submitted.10 pages including 8 figures(1 large postscript figure file) uses kjhantwo.sty .Also available at http://astro.snu.ac.kr/preprint1997.htm

Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults

Context: Prospective cohort studies have identified an association between cannabis use and later psychosis-related outcomes, but concerns remain about unmeasured confounding variables. The use of sibling pair analysis reduces the influence of unmeasured residual confounding