437 research outputs found

    TOWARDS ASSESSING PASSWORD WORKAROUNDS AND PERCEIVED RISK TO DATA BREACHES FOR ORGANIZATIONAL CYBERSECURITY RISK MANAGEMENT TAXONOMY

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    Cybersecurity involves a broad range of techniques, including cyber-physical, managerial, and technical, while authentication provides a layer of protection for Information Systems (IS) against data breaches. The recent COVID-19 pandemic brought a tsunami of data breach incidents worldwide. Authentication serves as a mechanism for IS against unauthorized access utilizing various defense techniques, with the most popular and frequently used technique being passwords. However, the dramatic increase of user accounts over the past few decades has exposed the realization that technological measures alone cannot ensure high level of IS security; this leaves the end-users holding a critical role in protecting their organization and personal information. Despite users being more aware of password entropy, users still often participate in deviant password behaviors also known as ‘password workarounds’ or ‘shadow security’. These deviant password behaviors can put individuals and organizations at risk resulting in data privacy issues, data loss, and ultimately a data breach incident. In this paper, we outline a research-in-progress study to build a risk taxonomy for organizations based on the to identify the risks associated with deviant password behaviors technique based on the constructs of users’ perceived cybersecurity risk of data breaches resulting from PassWord WorkArounds (PWWA) techniques. Additionally, this study aims to empirically assess significant mean difference between Subject Matter Experts (SMEs) and employees on their perceived cybersecurity risk of data breaches resulting from the deviant password behaviors and frequency of PWWA techniques usage

    An ethical matrix for the reintroduction of trafficked primates:a platyrrhine case study

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    The illegal primate trade is one of the major drivers of the decline of nonhuman primate populations and a threat to their wellbeing. Thousands of trafficked primates enter rescue centers every year, and their destiny (release back into the wild, long-term captivity, or euthanasia) involves controversial decisions and complex ethical considerations. To navigate these issues, we developed an ethical matrix, an ethical framework previously used to address conservation-related issues. We gathered information from studies on the reintroduction of trafficked platyrrhines in Latin America from 1990 to 2022 to develop the matrix. We found 22 studies performed in eight Latin American countries, which included howler monkeys, spider monkeys, woolly monkeys, capuchin monkeys, squirrel monkeys, marmosets, and tamarins. We found that the reintroduction of trafficked platyrrhines may yield positive results for the welfare of individuals and for the conservation of their taxa and some of the potential negative effects, such as spillover of infectious agents to free-ranging populations or to human populations, or competition for resources between reintroduced monkeys and resident conspecifics have not yet been documented in the scientific literature, although this does not mean that they do not occur. We conclude that the ethical matrix is a useful method to consider the interests of all potential stakeholders and that the reintroduction of trafficked primates may be a viable management option if the individual welfare of the animals is considered, programs comply with the IUCN and government guidelines, and the objective and justification of the reintroduction are clear

    Distributed under Creative Commons CC-BY 4.0 OPEN ACCESS Deer herbivory reduces web-building spider abundance by simplifying forest vegetation structure

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    ABSTRACT Indirect ecological effects are a common feature of ecological systems, arising when one species affects interactions among two or more other species. We examined how browsing by white-tailed deer (Odocoileus virginianus) indirectly affected the abundance and composition of a web-building spider guild through their effects on the structure of the ground and shrub layers of northern hardwood forests. We examined paired plots consisting of deer-free and control plots in the Allegheny Plateau region Pennsylvania and Northern Highlands region of Wisconsin. We recorded the abundance of seven types of webs, each corresponding to a family of web-building spiders. We quantified vegetation structure and habitat suitability for the spiders by computing a web scaffold availability index (WSAI) at 0.5 m and 1.0 m above the ground. At Northern Highlands sites, we recorded prey availability. Spider webs were twice as abundant in deer-free plots compared to control plots, while WSAI was 7-12 times greater in deerfree plots. Prey availability was lower in deer-free plots. With the exception of funnel web-builders, all spider web types were significantly more abundant in deer-free plots. Both deer exclusion and the geographic region of plots were significant predictors of spider community structure. In closed canopy forests with high browsing pressure, the low density of tree saplings and shrubs provides few locations for web-building spiders to anchor webs. Recruitment of these spiders may become coupled with forest disturbance events that increase tree and shrub recruitment. By modifying habitat structure, deer appear to indirectly modify arthropod food web interactions. As deer populations have increased in eastern North America over the past several decades, the effects of deer on web-building spiders may be widespread

    The XMM Cluster Survey: Evidence for energy injection at high redshift from evolution of the X-ray luminosity-temperature relation

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    We measure the evolution of the X-ray luminosity-temperature (L_X-T) relation since z~1.5 using a sample of 211 serendipitously detected galaxy clusters with spectroscopic redshifts drawn from the XMM Cluster Survey first data release (XCS-DR1). This is the first study spanning this redshift range using a single, large, homogeneous cluster sample. Using an orthogonal regression technique, we find no evidence for evolution in the slope or intrinsic scatter of the relation since z~1.5, finding both to be consistent with previous measurements at z~0.1. However, the normalisation is seen to evolve negatively with respect to the self-similar expectation: we find E(z)^{-1} L_X = 10^{44.67 +/- 0.09} (T/5)^{3.04 +/- 0.16} (1+z)^{-1.5 +/- 0.5}, which is within 2 sigma of the zero evolution case. We see milder, but still negative, evolution with respect to self-similar when using a bisector regression technique. We compare our results to numerical simulations, where we fit simulated cluster samples using the same methods used on the XCS data. Our data favour models in which the majority of the excess entropy required to explain the slope of the L_X-T relation is injected at high redshift. Simulations in which AGN feedback is implemented using prescriptions from current semi-analytic galaxy formation models predict positive evolution of the normalisation, and differ from our data at more than 5 sigma. This suggests that more efficient feedback at high redshift may be needed in these models.Comment: Accepted for publication in MNRAS; 12 pages, 6 figures; added references to match published versio

    Expression of Epstein–Barr Virus–Encoded Small RNA (by the EBER-1 Gene) in Liver Specimens from Transplant Recipients with Post-Transplantation Lymphoproliferative Disease

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    Epstein-Barr virus (EBV)—associated post-transplantation lymphoproliferative disease (PTLD) develops in 1 to 10 percent of transplant recipients, in whom it can be treated by a reduction in the level of immunosuppression. We postulated that the tissue expression of the small RNA transcribed by the EBER-1 gene during latent EBV infection would identify patients at risk for PTLD. We studied EBER-1 gene expression in liver specimens obtained from 24 patients 2 days to 22 months before the development of PTLD, using in situ hybridization with an oligonucleotide probe. Control specimens were obtained from 20 recipients of allografts with signs of injury due to organ retrieval, acute graft rejection, or viral hepatitis in whom PTLD had not developed 9 to 71 months after the biopsy. Of the 24 patients with PTLD, 17 (71 percent) had specimens in which 1 to 40 percent of mononuclear cells were positive for the EBER-1 gene. In addition, 10 of these 17 patients (59 percent) had specimens with histopathological changes suggestive of EBV hepatitis. In every case, EBER-1—positive cells were found within the lymphoproliferative lesions identified at autopsy. Only 2 of the 20 controls (10 percent) had specimens with EBER-1—positive cells (P<0.001), and such cells were rare. EBER-1 gene expression in liver tissue precedes the occurrence of clinical and histologic PTLD. The possibility of identifying patients at risk by the method we describe here and preventing the occurrence of PTLD by a timely reduction of immunosuppression needs to be addressed by future prospective studies. (N Engl J Med 1992;327:1710–4.), POST-TRANSPLANTATION lymphoproliferative disease (PTLD), either polyclonal or monoclonal, complicates the clinical course of 1 to 10 percent of organ-transplant recipients.123 Immunohistochemical studies have demonstrated that the lymphoid cells within the lesions of PTLD almost invariably contain Epstein–Barr virus (EBV), primarily in a state of latent infection.4,5 The EBER-1 gene is expressed early during latent EBV infection and codes for a small messenger RNA (mRNA) expressed at up to 107 copies per cell.6 We and others have previously demonstrated the value of the detection of EBER-1 RNA for identifying EBV-infected cells in formalin-fixed paraffin-embedded tissues.7,8 In the current investigation, we used… © 1992, Massachusetts Medical Society. All rights reserved

    High-Resolution Sequencing and Modeling Identifies Distinct Dynamic RNA Regulatory Strategies

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    Cells control dynamic transitions in transcript levels by regulating transcription, processing, and/or degradation through an integrated regulatory strategy. Here, we combine RNA metabolic labeling, rRNA-depleted RNA-seq, and DRiLL, a novel computational framework, to quantify the level; editing sites; and transcription, processing, and degradation rates of each transcript at a splice junction resolution during the LPS response of mouse dendritic cells. Four key regulatory strategies, dominated by RNA transcription changes, generate most temporal gene expression patterns. Noncanonical strategies that also employ dynamic posttranscriptional regulation control only a minority of genes, but provide unique signal processing features. We validate Tristetraprolin (TTP) as a major regulator of RNA degradation in one noncanonical strategy. Applying DRiLL to the regulation of noncoding RNAs and to zebrafish embryogenesis demonstrates its broad utility. Our study provides a new quantitative approach to discover transcriptional and posttranscriptional events that control dynamic changes in transcript levels using RNA sequencing data.National Human Genome Research Institute (U.S.) (Centers for Excellence in Genomics Science 1P50HG006193-01)Howard Hughes Medical InstituteNational Institutes of Health (U.S.) (Pioneer Award)Massachusetts Institute of Technology. William Asbjornsen Albert Memorial FellowshipXerox Fellowship Progra

    Perceptions of health and wellbeing among employees in a work integration social enterprise in Sweden

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    Background: Work Integration Social Enterprises (WISEs) constitute an important vehiclefor providing employment opportunities for disadvantaged groups.Objective: The goal of this qualitative case study is to explore perceptions of health andwellbeing among employees working in a WISE located in the Gävleborg region, in eastcentral Sweden.Methods: Data were gathered using 16 in-depth, semi-structured interviews with thesocial enterprise employees.Results: Findings were categorized into three main categories: the importance of financialindependence and societal benefits; team spirit and a sense of belonging; and improvedquality of life and wellbeing.Conclusion: The participants perceived that working in the WISE gave them a feeling offreedom and increased their self-esteem because of the possibility to earn an income.Also, they were satisfied with their job (e.g., with regard to work quality and flexibility)and believed that their work contributed to society. Moreover, through working in a WISE,the participants felt a sense of belonging and togetherness through interaction with coworkersand managers, and an improved quality of life for themselves and their families

    A Report Card on Urban Erosion and Sedimentation Control in North Carolina

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    In 1973 North Carolina enacted what has become one of the most stringent erosion and sedimentation control programs in the nation. This article discusses how a survey of 128 construction sites in North Carolina turned up evidence that practice falls short of state goals to curb urban erosion and sedimentation. The authors then discuss policy options to remedy these shortcomings

    S100A8 & S100A9: alarmin mediated inflammation in tendinopathy

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    Alarmins S100A8 and S100A9 are endogenous molecules released in response to environmental triggers and cellular damage. They are constitutively expressed in immune cells such as monocytes and neutrophils and their expression is upregulated under inflammatory conditions. The molecular mechanisms that regulate inflammatory pathways in tendinopathy are largely unknown therefore identifying early immune effectors is essential to understanding the pathology. Based on our previous investigations highlighting tendinopathy as an alarmin mediated pathology we sought evidence of S100A8 &amp; A9 expression in a human model of tendinopathy and thereafter, to explore mechanisms whereby S100 proteins may regulate release of inflammatory mediators and matrix synthesis in human tenocytes. Immunohistochemistry and quantitative RT-PCR showed S100A8 &amp; A9 expression was significantly upregulated in tendinopathic tissue compared with control. Furthermore, treating primary human tenocytes with exogenous S100A8 &amp; A9 significantly increased protein release of IL-6, IL-8, CCL2, CCL20 and CXCL10; however, no alterations in genes associated with matrix remodelling were observed at a transcript level. We propose S100A8 &amp; A9 participate in early pathology by modulating the stromal microenvironment and influencing the inflammatory profile observed in tendinopathy. S100A8 and S100A9 may participate in a positive feedback mechanism involving enhanced leukocyte recruitment and release of pro-inflammatory cytokines from tenocytes that perpetuates the inflammatory response within the tendon in the early stages of disease

    Spatial Guilds in the Serengeti Food Web Revealed by a Bayesian Group Model

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    Food webs, networks of feeding relationships among organisms, provide fundamental insights into mechanisms that determine ecosystem stability and persistence. Despite long-standing interest in the compartmental structure of food webs, past network analyses of food webs have been constrained by a standard definition of compartments, or modules, that requires many links within compartments and few links between them. Empirical analyses have been further limited by low-resolution data for primary producers. In this paper, we present a Bayesian computational method for identifying group structure in food webs using a flexible definition of a group that can describe both functional roles and standard compartments. The Serengeti ecosystem provides an opportunity to examine structure in a newly compiled food web that includes species-level resolution among plants, allowing us to address whether groups in the food web correspond to tightly-connected compartments or functional groups, and whether network structure reflects spatial or trophic organization, or a combination of the two. We have compiled the major mammalian and plant components of the Serengeti food web from published literature, and we infer its group structure using our method. We find that network structure corresponds to spatially distinct plant groups coupled at higher trophic levels by groups of herbivores, which are in turn coupled by carnivore groups. Thus the group structure of the Serengeti web represents a mixture of trophic guild structure and spatial patterns, in contrast to the standard compartments typically identified in ecological networks. From data consisting only of nodes and links, the group structure that emerges supports recent ideas on spatial coupling and energy channels in ecosystems that have been proposed as important for persistence.Comment: 28 pages, 6 figures (+ 3 supporting), 2 tables (+ 4 supporting
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