3,089 research outputs found

    Plasduino: an inexpensive, general purpose data acquisition framework for educational experiments

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    Based on the Arduino development platform, Plasduino is an open-source data acquisition framework specifically designed for educational physics experiments. The source code, schematics and documentation are in the public domain under a GPL license and the system, streamlined for low cost and ease of use, can be replicated on the scale of a typical didactic lab with minimal effort. We describe the basic architecture of the system and illustrate its potential with some real-life examples.Comment: 11 pages, 10 figures, presented at the XCIX conference of the Societ\`a Italiana di Fisic

    Liquefaction Hazard Mitigation by Prefabricated Vertical Drains

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    Liquefaction has typically been mitigated by in-situ densification; however vertical composite drains offer the possibility of preventing liquefaction and associated settlement while reducing the cost and time required for treatment. Three case histories are presented which describe the use of vertical drains to mitigate liquefaction hazard and techniques to control the flow of water exiting the drains. In addition, results from a test case are presented where controlled blasting techniques were used to evaluate drain performance in-situ. Blasting was successful in liquefying loose sand in an untreated test site. Similar blast charges were then detonated at adjacent sites treated with drains. Measurements demonstrated that the drains significantly increased the rate of pore pressure dissipation. In addition, the installation process typically densified the surrounding soil, thereby decreasing the liquefaction potential. Computer analyses successfully matched the measured response and suggest that the drains could be effective for earthquake events

    Involvement of Thyroid Hormones in the Expression of MHC class I Antigens During Ontogeny in Xenopus

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    The major histocompatibility complex (MHC) is a cluster of genes encoding products central to all major functions of the vertebrate immune system. Evidence for an MHC can be found in all vertebrate groups that have been examined except the jawless fishes. Expression of MHC class I and class II antigens early in ontogeny is critically important for development of T lymphocytes capable of discriminating self from nonself. Because of this essential role in T-cell development, the ontogeny of MHC expression in the South African clawed frog, Xenopus laevis, was studied. Previous studies of MHC class I expression in Xenopus laevis suggested that class I antigens are virtually absent from tadpole tissues until climax of metamorphosis. We therefore examined the possible role of thyroid hormones (TH) in the induction of class I. By flow cytometry, a small amount of class I expression was detectable on splenocytes and erythrocytes in untreated frogs at prometamorphic stages 55-58, and the amount increased significantly at the conclusion of metamorphic climax. Thus, metamorphosis is associated with increased intensity of class I expression. Neither inhibition nor acceleration of metamorphosis altered the timing of onset of class I expression. However, inhibition of metamorphosis prevented the increase in class I expression characteristic of adult cell populations. Because expression was not accelerated in TH-treated frogs or delayed in metamorphosis-inhibited frogs, it is unlikely that TH are the direct developmental cues that induce expression, although they seem to be required for the upregulation of class I expression occurring at metamorphosis. Differences in the pattern of expression in different subpopulations of cells suggest a complex pattern of regulation of expression of class I antigens during ontogeny

    Involvement of Thyroid Hormones in the Expression of MHC class I Antigens During Ontogeny in Xenopus

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    The major histocompatibility complex (MHC) is a cluster of genes encoding products central to all major functions of the vertebrate immune system. Evidence for an MHC can be found in all vertebrate groups that have been examined except the jawless fishes. Expression of MHC class I and class II antigens early in ontogeny is critically important for development of T lymphocytes capable of discriminating self from nonself. Because of this essential role in T-cell development, the ontogeny of MHC expression in the South African clawed frog, Xenopus laevis, was studied. Previous studies of MHC class I expression in Xenopus laevis suggested that class I antigens are virtually absent from tadpole tissues until climax of metamorphosis. We therefore examined the possible role of thyroid hormones (TH) in the induction of class I. By flow cytometry, a small amount of class I expression was detectable on splenocytes and erythrocytes in untreated frogs at prometamorphic stages 55-58, and the amount increased significantly at the conclusion of metamorphic climax. Thus, metamorphosis is associated with increased intensity of class I expression. Neither inhibition nor acceleration of metamorphosis altered the timing of onset of class I expression. However, inhibition of metamorphosis prevented the increase in class I expression characteristic of adult cell populations. Because expression was not accelerated in TH-treated frogs or delayed in metamorphosis-inhibited frogs, it is unlikely that TH are the direct developmental cues that induce expression, although they seem to be required for the upregulation of class I expression occurring at metamorphosis. Differences in the pattern of expression in different subpopulations of cells suggest a complex pattern of regulation of expression of class I antigens during ontogeny

    Parametric Amplification of Nonlinear Response of Single Crystal Niobium

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    Giant enhancement of the nonlinear response of a single crystal Nb sample, placed in {\it a pumping ac magnetic field}, has been observed experimentally. The experimentally observed amplitude of the output signal is about three orders of magnitude higher than that seen without parametric pumping. The theoretical analysis based on the extended double well potential model provides a qualitative explanation of the experimental results as well as new predictions of two bifurcations for specific values of the pumping signal.Comment: 6 pages, 10 figure

    Benefits of Artificially Generated Gravity Gradients for Interferometric Gravitational-Wave Detectors

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    We present an approach to experimentally evaluate gravity gradient noise, a potentially limiting noise source in advanced interferometric gravitational wave (GW) detectors. In addition, the method can be used to provide sub-percent calibration in phase and amplitude of modern interferometric GW detectors. Knowledge of calibration to such certainties shall enhance the scientific output of the instruments in case of an eventual detection of GWs. The method relies on a rotating symmetrical two-body mass, a Dynamic gravity Field Generator (DFG). The placement of the DFG in the proximity of one of the interferometer's suspended test masses generates a change in the local gravitational field detectable with current interferometric GW detectors.Comment: 16 pages, 4 figure

    Development of a lightweight cryogenic insulating system Final report, 30 Jun. 1964 - 31 May 1966

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    Lightweight external panel insulation systems for thermal protection of cryogenic launch vehicle propellant tank

    Heat and water transport in soils and across the soil-atmosphere interface: 1. Theory and different model concepts

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    Evaporation is an important component of the soil water balance. It is composed of water flow and transport processes in a porous medium that are coupled with heat fluxes and free air flow. This work provides a comprehensive review of model concepts used in different research fields to describe evaporation. Concepts range from nonisothermal two-phase flow, two-component transport in the porous medium that is coupled with one-phase flow, two-component transport in the free air flow to isothermal liquid water flow in the porous medium with upper boundary conditions defined by a potential evaporation flux when available energy and transfer to the free airflow are limiting or by a critical threshold water pressure when soil water availability is limiting. The latter approach corresponds with the classical Richards equation with mixed boundary conditions. We compare the different approaches on a theoretical level by identifying the underlying simplifications that are made for the different compartments of the system: porous medium, free flow and their interface, and by discussing how processes not explicitly considered are parameterized. Simplifications can be grouped into three sets depending on whether lateral variations in vertical fluxes are considered, whether flow and transport in the air phase in the porous medium are considered, and depending on how the interaction at the interface between the free flow and the porous medium is represented. The consequences of the simplifications are illustrated by numerical simulations in an accompanying paper
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