817 research outputs found
Thermal energy storage sizing for industrial waste-heat utilization in district heating: A model predictive control approach
Thermal energy storage (TES) is a key technology for enabling increased utilization of industrial waste heat in district heating. The ability of TES to equalize offsets in demand and supply depends strongly on the sizing, control and integration in a heating plant. We consider the problem of sizing TES in heating plants utilizing a varying waste-heat source. To this end, we propose a combined dynamic simulation and model predictive control approach that accounts for the dynamics and optimal control of the heating plant with TES. A case study has been carried out on a district-heating plant located in Norway, with 90% of its annual heat production being heat recovered from the off-gas from a ferrosilicon plant. We evaluate the effective peak-heating reduction with different TES sizes and the energy-to-heat-flow-ratio for the TES discharging periods as performance metrics. For the case study, our results suggest that a modest TES tank volume of 1500 m3 is sufficient to achieve a half-year peak-heating reduction of 12% and comparable performance with larger volumes. The proposed methodology constitutes a numerically tractable means of incorporating the impact of model predictive control on the sizing of TES for heating plants with time-varying waste-heat supply and demand. Keywords Thermal energy storageWaste-heat utilizationDistrict heatingModel predictive controlpublishedVersio
Server-Setup
Eine Zope/Plone-Installation hängt stark von den Anforderungen ab, die diese Installation erfüllen soll. Anhand der an der Humboldt-Universität zu Berlin verwendeten Konfiguration sollen die damit gelösten, aber auch die dadurch neu entstandenen Probleme hier näher betrachtet werden. Einige Aspekte dieser Probleme und Lösungen treffen nicht nur die Server-Administratoren, sondern auch die Entwickler und Autoren von Zope/Plone
Concepts in Animal Parasitology, Chapter 01: Introduction to Animal Parasitology
Chapter 1 in Concepts in Animal Parasitology, an introduction to the topic, by Scott L. Gardner, Daniel R. Brooks, and Klaus Rohde. 2024. S. L. Gardner and S. A. Gardner, editors. Zea Books, Lincoln, Nebraska, United States. doi: 10.32873/unl.dc.ciap00
Query Optimization Techniques For Scaling Up To Data Variety
Even though Data Lakes are efficient in terms of data storage, they increase the complexity of query processing; this can lead to expensive query execution. Hence, novel techniques for generating query execution plans are demanded. Those techniques have to be able to exploit the main characteristics of Data Lakes. Ontario is a federated query engine capable of processing queries over heterogeneous data sources. Ontario uses source descriptions based on RDF Molecule Templates, i.e., an
abstract description of the properties belonging to the entities in the unified schema of the data in the Data Lake. This thesis proposes new heuristics tailored to the problem of query processing over heterogeneous data sources including heuristics specifically designed for certain data models. The proposed heuristics are integrated into the Ontario query optimizer. Ontario is compared to state-of-the-art RDF query engines in order to study the overhead introduced by considering heterogeneity during query processing. The results of the empirical evaluation suggest that there is no significant overhead when considering heterogeneity. Furthermore, the baseline version of Ontario is compared to two different sets of additional heuristics, i.e., heuristics specifically designed for certain data models and heuristics that do not consider the data model. The analysis of the obtained experimental results shows that source-specific heuristics are able to improve query performance. Ontario optimization techniques are able to generate effective and efficient query plans that can be executed over heterogeneous data sources in a Data Lake
Comorbidity Between Major Depression and Alcohol Use Disorder From Adolescence to Adulthood
Background—Limited information exists regarding the long-term development of comorbidity
between Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD; abuse/dependence).
Using a representative prospective study, we examine multiple aspects pertaining to MDD+AUD
comorbidity, with a focus on the relation between disorders across periods (adolescence, early
adulthood, adulthood) and cumulative impairments by age 30.
Method—816 participants were diagnostically interviewed at ages 16, 17, 24, and 30.
Results—Rates of comorbid MDD+AUD were low in adolescence (2%), but increased in early
adulthood (10%) and adulthood (7%). Rates of cumulative comorbidity were elevated (21%).
Most individuals with a history of MDD or AUD had the other disorder, except for women with
MDD. Prospectively, adolescent AUD predicted early adult MDD, while early adult MDD
predicted adult AUD. Compared to pure disorders, MDD+AUD was associated with higher risk of
alcohol dependence, suicide attempt, lower global functioning, and life dissatisfaction.
Conclusions—Lifetime rates of comorbid MDD+AUD were considerably higher than in crosssectional
studies. Comorbidity was partly explained by bidirectional and developmentally-specific
associations and predicted selected rather than generalized impairments. Clinically, our findings
emphasize the need to always carefully assess comorbidity in patients with MDD or AUD, taking
into account concurrency and developmental timing
Adolescent suicide attempts and adult adjustment
Background: Adolescent suicide attempts are disproportionally prevalent and
frequently of low severity, raising questions regarding their long-term prognostic
implications. In this study, we examined whether adolescent attempts were asso-
ciated with impairments related to suicidality, psychopathology, and psychosocial
functioning in adulthood (objective 1) and whether these impairments were better
accounted for by concurrent adolescent confounders (objective 2).
Method: Eight
hundred and sixteen adolescents were assessed using interviews and question-
naires at four time points from adolescence to adulthood. We examined whether
lifetime suicide attempts in adolescence (by T2, mean age 17) predicted adult out-
comes (by T4, mean age 30) using linear and logistic regressions in unadjusted
models (objective 1) and adjusting for sociodemographic background, adolescent
psychopathology, and family risk factors (objective 2).
Results: In unadjusted
analyses, adolescent suicide attempts predicted poorer adjustment on all outcomes,
except those related to social role status. After adjustment, adolescent attempts
remained predictive of axis I and II psychopathology (anxiety disorder, antisocial
and borderline personality disorder symptoms), global and social adjustment,
risky sex, and psychiatric treatment utilization. However, adolescent attempts
no longer predicted most adult outcomes, notably suicide attempts and major
depressive disorder. Secondary analyses indicated that associations did not differ
by sex and attempt characteristics (intent, lethality, recurrence).
Conclusions:
Adolescent suicide attempters are at high risk of protracted and wide-ranging im-
pairments, regardless of the characteristics of their attempt. Although attempts
specifically predict (and possibly influence) several outcomes, results suggest that
most impairments reflect the confounding contributions of other individual and
family problems or vulnerabilites in adolescent attempters
The impact of endovascular rescue therapy on the clinical and radiological outcome after aneurysmal subarachnoid hemorrhage: a safe and effective treatment option for hemodynamically relevant vasospasm?
OBJECTIVE: Cerebral vasospasm (CVS) represents one of the multiple contributors to delayed cerebral ischemia (DCI) in patients with aneurysmal subarachnoid hemorrhage (aSAH). Especially the management of CVS, refractory to medical treatment, is a challenging task during the acute phase after aSAH. Endovascular rescue therapies (ERT), such as medical and mechanical dilation, are possible treatment options on an individual basis. However, data about the influence on the patients' functional outcomes are limited. This study aims to assess the impact of ERT on the long-term functional outcome in aSAH-patients with refractory CVS. METHODS: We performed a retrospective analysis of aSAH patients treated between 2012 and 2018. CVS was considered refractory, if it persisted despite oral/intravenous nimodipine application and induced hypertension. The decision to perform ETR was made on an individual basis, according to the detection of “tissue at risk” on computed tomography perfusion (CTP) scans and CVS on computed tomography angiography (CTA) or digital subtraction angiography (DSA). The functional outcome was assessed according to the modified Rankin scale (mRS) 3 months after the ictus, whereas an mRS ≤ 2 was considered as a good outcome. RESULTS: A total of 268 patients were included. Out of these, 205 patients (76.5%) were treated without ERT (group 1) and 63 patients (23.5%) with ERT (group 2). In 20 patients (31.8%) balloon dilatation was performed, in 23 patients (36.5%) intra-arterial nimodipine injection alone, and in 20 patients (31.8%) both procedures were combined. Considering only the patient group with DCI, the patients who were treated with ERT had a significantly better outcome compared to the patients without ERT (Mann–Whitney test, p = 0.02). CONCLUSION: Endovascular rescue therapies resulted in a significantly better functional outcome in patients with DCI compared to the patient group treated without ETR. CTP and CTA-based identification of “tissue at risk” might be a reliable tool for patient selection for performing ERT
Angioplasty with the scepter C dual lumen balloon catheter and postprocedural result evaluation in patients with subarachnoid hemorrhage related vasospasms
Open-Access-Publikationsfonds 202
Verbundmöglichkeiten von Kindergarten, Grundschule und Sekundarstufe I im Hinblick auf den Einsatz von bilingualem Unterricht
Die zentralen Ziele dürften heutzutage kaum mehr kontrovers sein. Junge Europäer sollten
zusätzlich zu ihrer Muttersprache (L1) mindestens zwei Sprachen so weit lernen, dass sie
funktional für die Ansprüche des späteren Lebens ausreichen. Um einem differenzierten
Arbeitsmarkt gerecht werden zu können, sollte das Sprachenangebot so vielfältig wie möglich
gestaltet werden und in allen Schulformen möglichst flächendeckend zur Verfügung stehen.
Eine Elitebildung ist dabei unbedingt zu vermeiden. FĂĽr jede der unterrichteten Sprachen
sollte ein ausreichend hohes Schriftlichkeitsniveau gewährleistet werden, die betreffende
Sprache sollte also hinreichend lange gefördert werden. Wichtig ist vor allem, dass in Zukunft
die regional vorhandenen kleineren Sprachen verstärkt einbezogen werden. Wer die
Sprachenvielfalt in Europa wirklich erhalten will, muss dafĂĽr sorgen, dass z. B. in
multilingualen Gebieten auch jene Sprachen schulisch gefördert werden, die bislang gar nicht
oder nur marginal im öffentlichen Erziehungssystem berücksichtigt wurden (ausführlicher z.
B. Wode, 1990, 1992, 1995, 1998a). Eine integrierte Konzeption von bilingualem Unterricht
(BIU) im Verbund von Kindergarten, Grundschule und Sekundarstufe I könnte all diesen
Anforderungen gerecht werden
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