A Review of \u3ci\u3eMinilimosina (Svarciella) \u3c/i\u3e Rohacek, with Descriptions of Fourteen New Species (Diptera: Sphaeroceridae)

A worldwide review of Minilimosina (Svarciella) Rohicek 1983, comprising 27 species, is provided, with data about the primary types, published descriptions and figures, synonyms and distribution including new records. A key to Svarciella species is presented and 14 new species are described and illustrated: M. floreni (Sweden), M. aterga, M. fanta, M. furculipexa, M. brachyptera, M. amphicuspa (all Nepal), M. triplex, M. comigera (both Malaysia), M. concinna, M. hastata (both Philippines), M. spinifera (Papua New Guinea), M. flagrella (Bismarck Is.), M. xanthosceles (Ecuador) and M. xestops (USA: Florida). M. furculisterna (Deeming 1969) is redescribed, including the previously undescribed female, and recorded from Japan. The female of M. unica (Papp 1973) is described for the first time and the species is recorded from northern Europe. M. hackmani (Rohicek 1977) is removed from synonymy with M. dissimilicosta (Spuler 1925) and synonymized under M. unica (Papp). M. paravitripennis (Papp 1973) is a new synonym of M. vitripennis (Zetterstedt 1847). The egg of M. concinna sp.n. is described and illustrated. The phylogeny and biogeography of world Svarciella species are discussed

A Review of \u3ci\u3eMinilimosina (Svarciella) \u3c/i\u3e Rohacek, with Descriptions of Fourteen New Species (Diptera: Sphaeroceridae)

A worldwide review of Minilimosina (Svarciella) Rohicek 1983, comprising 27 species, is provided, with data about the primary types, published descriptions and figures, synonyms and distribution including new records. A key to Svarciella species is presented and 14 new species are described and illustrated: M. floreni (Sweden), M. aterga, M. fanta, M. furculipexa, M. brachyptera, M. amphicuspa (all Nepal), M. triplex, M. comigera (both Malaysia), M. concinna, M. hastata (both Philippines), M. spinifera (Papua New Guinea), M. flagrella (Bismarck Is.), M. xanthosceles (Ecuador) and M. xestops (USA: Florida). M. furculisterna (Deeming 1969) is redescribed, including the previously undescribed female, and recorded from Japan. The female of M. unica (Papp 1973) is described for the first time and the species is recorded from northern Europe. M. hackmani (Rohicek 1977) is removed from synonymy with M. dissimilicosta (Spuler 1925) and synonymized under M. unica (Papp). M. paravitripennis (Papp 1973) is a new synonym of M. vitripennis (Zetterstedt 1847). The egg of M. concinna sp.n. is described and illustrated. The phylogeny and biogeography of world Svarciella species are discussed

The Chronic Diseases Clinic of Ifakara (CDCI)- establishing a model clinic for chronic care delivery in rural sub-Saharan Africa

The rollout of antiretroviral drugs in sub-Saharan Africa to address the huge health impact of the HIV pandemic has been one of the largest projects undertaken in medical history and is an unprecedented medical success story. However, the path has been and still is characterized by many far reaching implementational challenges. Here, we report on the building and maintaining of a role model clinic in Ifakara, rural Southwestern Tanzania, within a collaborative project to support HIV services within the national program, training for staff and integrated research to better understand local needs and improve patients' outcomes

Inflammatory myopathy and severe rhabdomyolysis induced by leuprolide acetate therapy for prostate cancer: a case report

<p>Abstract</p> <p>Introduction</p> <p>Leuprolide acetate is a synthetic analog of gonadotropin-releasing hormone used for the treatment of prostate cancer. Its side effects are hot flashes, nausea, and fatigue. We report a case of a patient with proximal inflammatory myopathy accompanied by severe rhabdomyolysis and renal failure following the second application of leuprolide acetate. Drug withdrawal and steroid therapy resulted in remission within six weeks of the diagnosis. To the best of our knowledge, our case report describes the second case of leuprolide acetate-induced inflammatory myopathy and the first case of severe leuprolide acetate-induced rhabdomyolysis and renal failure in the literature.</p> <p>Case presentation</p> <p>A 64-year-old Swiss Caucasian man was admitted to the hospital because of progressive proximal muscle weakness, dyspnea, and oliguria. He had been treated twice with leuprolide acetate in monthly doses. We performed a muscle biopsy, which excluded other causes of myopathy. The patient's renal failure and rhabdomyolysis were treated with rehydration and steroid therapy.</p> <p>Conclusion</p> <p>The aim of our case report is to highlight the rare but severe side effects associated with leuprolide acetate therapy used to treat patients with inflammatory myopathy: severe rhabdomyolysis and renal failure.</p

A portable prototype magnetometer to differentiate ischemic and non-ischemic heart disease in patients with chest pain

Background: Magnetocardiography (MCG) is a non-invasive technique used to measure and map cardiac magnetic fields. We describe the predictive performance of a portable prototype magnetometer designed for use in acute and routine clinical settings. We assessed the predictive ability of the measurements derived from the magnetometer for the ruling-out of healthy subjects and patients whose chest pain has a non-ischemic origin from those with ischemic heart disease (IHD). Methods: MCG data were analyzed from a technical performance study, a pilot clinical study, and a young healthy reference group. Participants were grouped to enable differentiation of those with IHD versus non-IHD versus controls: Group A (70 IHD patients); Group B (69 controls); Group C (37 young healthy volunteers). Scans were recorded in an unshielded room. Between-group differences were explored using analysis of variance. The ability of 10 candidate MCG predictors to predict normal/abnormal cases was analyzed using logistic regression. Predictive performance was internally validated using repeated five-fold cross-validation. Results: Three MCG predictors showed a significant difference between patients and age-matched controls (P<0.001); eight predictors showed a significant difference between patients and young healthy volunteers (P<0.001). Logistic regression comparing patients with controls yielded a specificity of 35.0%, sensitivity of 95.4%, and negative predictive value for the ruling-out of IHD of 97.8% (area under the curve 0.78). Conclusion: This analysis represents a preliminary indication that the portable magnetometer can help rule-out healthy subjects and patients whose chest pain has a non-ischemic origin from those with IHD

Should adrenaline be used in patients with hemodynamically stable anaphylaxis? Incident case control study nested within a retrospective cohort study

Although adrenaline (epinephrine) is a cornerstone of initial anaphylaxis treatment, it is not often used. We sought to assess whether use of adrenaline in hemodynamically stable patients with anaphylaxis could prevent the development of hypotension. We conducted a retrospective cohort study of 761 adult patients with anaphylaxis presenting to the emergency department (ED) of a tertiary care hospital over a 10-year period. We divided the patients into two groups according to the occurrence of hypotension and compared demographic characteristics, clinical features, treatments and outcomes. Of the 340 patients with anaphylaxis who were normotensive at first presentation, 40 patients experienced hypotension during their ED stay. The ED stay of the hypotension group was significantly longer than that of patients who did not experience hypotension (496 min vs 253 min, P = 0.000). Adrenaline use in hemodynamically stable anaphylaxis patient was independently associated with a lower risk of developing in-hospital occurrence of hypotension: OR, 0.254 [95% CI, 0.091-0.706]. Adrenaline use in hemodynamically stable anaphylaxis patients was associated with a reduced risk of developing in-hospital occurrence of hypotension. Adverse events induced by adrenaline were rare when the intramuscular route was used