A cluster randomised controlled trial of a comprehensive accreditation intervention to reduce alcohol consumption at community sports clubs: study protocol

Introduction: Excessive alcohol consumption isresponsible for considerable harm from chronicdisease and injury. Within most developed countries,members of sporting clubs consume alcohol at levels above that of communities generally. Despite the potential benefits of interventions to address alcohol consumption in sporting clubs, there have been no randomised controlled trials to test the effectiveness of these interventions. The aim of this study is to examine the effectiveness of a comprehensive accreditation intervention with community football clubs (Rugby League, Rugby Union, soccer/association football and Australian Rules football) in reducing excessive alcohol consumption by club members.Methods and analysis: The study will be conducted in New South Wales, Australia, and employ a cluster randomised controlled trial design. Half of the football clubs recruited to the trial will be randomised to receive an intervention implemented over two and a half winter sporting seasons. The intervention is based on social ecology theory and is comprehensive in nature, containing multiple elements designed to decrease the supply of alcohol to intoxicated members, cease the provision of cheap and free alcohol, increase the availability and costattractiveness of non-alcoholic and low-alcoholic beverages, remove high alcohol drinks and cease drinking games. The intervention utilises a three-tiered accreditation framework designed to motivate intervention implementation. Football clubs in the control group will receive printed materials on topics unrelated to alcohol. Outcome data will be collected pre- and postintervention through cross-sectional telephone surveys of club members. The primary outcome measure will be alcohol consumption by club members at the club, assessed using a graduated frequency index and a seven day diary.Ethics and dissemination: The study was approved by The University of Newcastle Human Research Ethics Committee (reference: H-2008-0432). Study findings will be disseminated widely through peer-reviewed publications and conference presentations.<br /

Adaptive Management of Winter Elk Feedgrounds in Western Wyoming as a Long-Term Strategy for Reducing Brucellosis in Elk While Maintaining Separation from Cattle: A Work in Progress

Brucellosis is of large economic and management concern in the Greater Yellowstone Ecosystem (GYE) where wildlife remain the last reservoir of the disease in the United States. Wyoming Game and Fish Department (WGFD) management of brucellosis has focused on separation of elk (Cervus elaphus) and cattle (Bos taurus) through operation of 22 winter feedgrounds, which originated to prevent elk starvation and elk damage. Although feedgrounds perpetuate the spread of brucellosis among elk, they are largely maintained to prevent disease spillover to cattle. Despite efforts, recent brucellosis occurrences in Wyoming cattle during 2004-2008 were linked to feedground elk. Therefore, numerous research projects conducted during 2006-2008 were aimed at developing feedground management strategies that lead to long-term brucellosis reductions in elk. Major research results lead the WGFD to development of the Target Feedground Project, which manipulates feeding management to reduce brucellosis in elk. This project was first implemented in winter 2007-08 and is conducted exclusively at target feedgrounds, where perceived elk-cattle commingling risk is low and there is a high potential for elk to free range in late winter/early spring. The first objective is to reduce elk densities while on feedgrounds by using low-density feeding. The second objective is to reduce duration of high elk concentration by manipulating end-feeding season date through systematic reductions in hay rations in late winter and early spring, with the goal of ending an average of 3-4 weeks earlier than long-term means. Advantages of this project, if successful, are sustainable reductions in elk brucellosis and decreased risk to cattle, lower elk feeding costs, and continued operation of feedgrounds to minimize elk-cattle commingling, elk damage, and sustain elk numbers that meet public expectation. Disadvantages are that the project is not suitable for all feedgrounds and elk on target feedgrounds remain susceptible to new diseases that may arise

Geo-Statistical Methods for Detecting Elk Parturition Sites from GPS Collar Data

There is an increasing awareness of the importance of juvenile survival in ungulate population dynamics, and the accurate prediction of parturition habitat may allow for more effective management. Detecting birth sites in a statistically rigorous way, however, often requires intensive field efforts that may not be possible for all studies. We developed a hierarchical two-stage clustering analysis for identifying elk parturition locations, which can be conducted retrospectively using only GPS location data. We validated our approach using a dataset of 59 adult female elk ( Cervus elaphus) fitted with both a Global Positioning System (GPS) collar (30-minute sampling interval) and vaginal implant transmitter (VIT) For the top parameter set, approximately 80% of estimable parturition sites were within 1 km of their respective VIT location. Roughly 10 % of our predicted birthing locations were over 2 km away from the VIT location, but many of these events could be filtered from the analyses due to their clustering attributes. Designed to minimize Type II errors this filtering also removes a subset of birthing sites that close to VIT locations, and magnitude of this effect varied across parameter sets. Sub-sampling of the GPS dataset from 30 min to 1, 2, 3, and 6 hour intervals resulted in modest reductions in the efficacy of our approach. With the use of GPS collars in ungulate studies on the rise, our approach provides managers with additional information on birth site locations at no additional cost over and above a typical GPS study

Population Hemoglobin Mean and Anemia Prevalence in Papua New Guinea: New Metrics for Defining Malaria Endemicity?

The hypothesis is that hemoglobin-based metrics are useful tools for estimating malaria endemicity and for monitoring malaria control strategies. The aim of this study is to compare population hemoglobin mean and anemia prevalence to established indicators of malaria endemicity, including parasite rates, rates of enlarged spleens in children, and records of (presumptive) malaria diagnosis among populations living with different levels of malaria transmission. Convenience sample, multisite cross-sectional household surveys conducted in Papua New Guinea. Correlations (r(2)) between population Hb mean and anemia prevalence and altitude, parasite rate, and spleen rate were investigated in children ages 2 to 10 years, and in the general population; 21,664 individuals from 156 different communities were surveyed. Altitude ranged from 5 to 2120 meters. In young children, correlations between altitude and parasite rate, population Hb mean, anemia prevalence, and spleen rate were high (r(2): -0.77, 0.73, -0.81, and -0.68; p&lt;0.001). In the general population, correlations between altitude and population Hb mean and anemia prevalence were 0.83 and 0.85, respectively. Among young children, parasite rate correlated highly with anemia prevalence, population Hb mean, and spleen rate (r(2): 0.81, -0.81, and 0.86; p&lt;0.001). Population Hb mean (corrected for direct altitude effects) increased with altitude, from 10.5 g/dl at &lt;500 m to 12.8 g/dl at &gt;1500 m (p&lt;0.001). In PNG, where Plasmodium vivax accounts for an important part of all malaria infections, population hemoglobin mean and anemia prevalence correlate well with altitude, parasite, and spleen rates. Hb measurement is simple and affordable, and may be a useful new tool, alone or in association with other metrics, for estimating malaria endemicity and monitoring effectiveness of malaria control programs. Further prospective studies in areas with different malaria epidemiology and different factors contributing to the burden of anemia are warranted to investigate the usefulness of Hb metrics in monitoring malaria transmission intensity

Raising rivals’ fixed costs

This article demonstrates that raising fixed costs can serve as a credible mechanism for a well placed firm to exclude its rivals. We identify a number of credible avenues, such as increased regulation, vexatious litigation and increased prices for essential inputs, through which such a firm can raise fixed costs. We show that for a wide range of oligopoly models this may be a profitable strategy, even if the firm’s own fixed costs are affected as much (or even more) than its rivals and even if it is less efficient. The resulting reduction in the number of firms in the market is detrimental to consumer welfare and hence worthy of scrutiny by competition and regulatory authorities

Effectiveness of Artemether/Lumefantrine for the Treatment of Uncomplicated Plasmodium vivax and P. falciparum Malaria in Young Children in Papua New Guinea

This study shows that artemether/lumefantrine provides a rapid clinical response against both Plasmodium falciparum and Plasmodium vivax clinical malaria, but is associated with a high rate of P. vivax recurrent clinical episodes due to relapsing infections from long-lasting hypnozoite

Tackling risky alcohol consumption in sport: a cluster randomised controlled trial of an alcohol management intervention with community football clubs

BACKGROUND: An increased prevalence of risky alcohol consumption and alcohol-related harm has been reported for members of sporting groups and at sporting venues compared with non-sporting populations. While sports clubs and venues represent opportune settings to implement strategies to reduce such risks, no controlled trials have been reported. The purpose of the study was to examine the effectiveness of an alcohol management intervention in reducing risky alcohol consumption and the risk of alcohol-related harm among community football club members. METHOD: A cluster randomised controlled trial of an alcohol management intervention was undertaken with non-elite, community football clubs and their members in New South Wales, Australia. Risky alcohol consumption (5+ drinks) at the club and risk of alcohol-related harm using the Alcohol Use Disorders Identification Test (AUDIT) were measured at baseline and postintervention. RESULTS: Eighty-eight clubs participated in the trial (n=43, INTERVENTION; n=45, CONTROL) and separate cross-sectional samples of club members completed the baseline (N=1411) and postintervention (N=1143) surveys. Postintervention, a significantly lower proportion of intervention club members reported: risky alcohol consumption at the club ( INTERVENTION: 19%; CONTROL: 24%; OR: 0.63 (95% CI 0.40 to 1.00); p=0.05); risk of alcohol-related harm ( INTERVENTION: 38%; CONTROL: 45%; OR: 0.58 (95% CI 0.38 to 0.87); p&lt;0.01); alcohol consumption risk ( INTERVENTION: 47%; CONTROL: 55%; OR: 0.60 (95% CI 0.41 to 0.87); p&lt;0.01) and possible alcohol dependence ( INTERVENTION: 1%; CONTROL: 4%; OR: 0.20 (95% CI 0.06 to 0.65); p&lt;0.01). CONCLUSIONS: With large numbers of people worldwide playing, watching and sports officiating, enhancing club-based alcohol management interventions could make a substantial contribution to reducing the burden of alcohol misuse in communities.<br /

Elk Contact Patterns and Potential Disease Transmission

Understanding the drivers of contact rates among individuals is critical to understanding disease dynamics and implementing targeted control measures. We studied the interaction patterns of 149 female elk (Cervus elaphus) distributed across five different regions of western Wyoming over three years, defining a contact as an approach within one body length (~2m). Using hierarchical models that account for correlations within individuals, pairs and groups, we found that pairwise contact rates within a group declined by a factor of three as group sizes increased 30-fold. Meanwhile, per capita contact rates increased with group size due to the increasing number of potential pairs. We found similar patterns for the duration of contacts. Supplemental feeding of elk had a limited impact on pairwise interaction rates and durations, but increased per capita rates more than two times higher. Variation in contact patterns were driven more by environmental factors such as group size than either individual or pairwise differences. Female elk in this region fall between the expectation of contact rates that linearly increase with group size (as assumed by pseudo-mass action models of disease transmission) or are constant with changes in group size (as assumed by frequency dependent transmission models). Our statistical approach decomposes the variation in contact rate into individual, dyadic, and environmental effects, which provides insight into those factors that are important for effective disease control programs

CEO pay, shareholder returns, and accounting profits

We assess the impact on CEO pay (including salary, cash bonus, and benefits in kind) of changes in both accounting and shareholder returns in 99 British companies in the years 1972-89. After correcting for heterogeneity biases inherent in the standard specifications of the problem, we find a strong positive relationship between CEO pay and within-company changes in shareholder returns, and no statistically significant relationship between CEO pay and within-company changes in accounting returns. Differences between firms in long-term average profitability do appear to have a substantial effect on CEO pay, while differences between firms in shareholder returns add nothing to the within-firm pay dynamics.These findings call into question the rationale for explicitly share-based incentive schemes

Coastally Trapped Wind Reversals: Progress toward Understanding

Coastally trapped wind reversals along the U.S. west coast, which are often accompanied by a northward surge of fog or stratus, are an important warm-season forecast problem due to their impact on coastal maritime activities and airport operations. Previous studies identified several possible dynamic mechanisms that could be responsible for producing these events, yet observational and modeling limitations at the time left these competing interpretations open for debate. In an effort to improve our physical understanding, and ultimately the prediction, of these events, the Office of Naval Research sponsored an Accelerated Research Initiative in Coastal Meteorology during the years 1993â 98 to study these and other related coastal meteorological phenomena. This effort included two field programs to study coastally trapped disturbances as well as numerous modeling studies to explore key dynamic mechanisms. This paper describes the various efforts that occurred under this program to provide an advancement in our understanding of these disturbances. While not all issues have been solved, the synoptic and mesoscale aspects of these events are considerably better understood.Most of the authors were supported through the Office of Naval Research Coastal Meteorology Accelerated Research Initiative, one of the authors (WTT) was supported by Program Element 0601153N, Naval Research Laboratory